|
LT2557517T
(lt)
*
|
2007-07-23 |
2023-01-10 |
The Chinese University Of Hong Kong |
Nukleino rūgščių sekos disbalanso nustatymas
|
|
CA2717320A1
(en)
|
2008-03-11 |
2009-09-17 |
Sequenom, Inc. |
Nucleic acid-based tests for prenatal gender determination
|
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
|
LT3783110T
(lt)
|
2009-11-05 |
2023-01-25 |
The Chinese University Of Hong Kong |
Vaisiaus genomo analizė iš motinos biologinio mėginio
|
|
EA034241B1
(ru)
*
|
2009-11-06 |
2020-01-21 |
Те Чайниз Юниверсити Ов Гонконг |
Способ пренатальной диагностики дисбаланса последовательности
|
|
EP3088532B1
(en)
|
2009-12-22 |
2019-10-30 |
Sequenom, Inc. |
Processes and kits for identifying aneuploidy
|
|
CN101921874B
(zh)
*
|
2010-06-30 |
2013-09-11 |
深圳华大基因科技有限公司 |
基于Solexa测序法的检测人类乳头瘤病毒的方法
|
|
US10167508B2
(en)
|
2010-08-06 |
2019-01-01 |
Ariosa Diagnostics, Inc. |
Detection of genetic abnormalities
|
|
US11203786B2
(en)
|
2010-08-06 |
2021-12-21 |
Ariosa Diagnostics, Inc. |
Detection of target nucleic acids using hybridization
|
|
US20140342940A1
(en)
|
2011-01-25 |
2014-11-20 |
Ariosa Diagnostics, Inc. |
Detection of Target Nucleic Acids using Hybridization
|
|
US20130040375A1
(en)
|
2011-08-08 |
2013-02-14 |
Tandem Diagnotics, Inc. |
Assay systems for genetic analysis
|
|
US11031095B2
(en)
|
2010-08-06 |
2021-06-08 |
Ariosa Diagnostics, Inc. |
Assay systems for determination of fetal copy number variation
|
|
US8700338B2
(en)
|
2011-01-25 |
2014-04-15 |
Ariosa Diagnosis, Inc. |
Risk calculation for evaluation of fetal aneuploidy
|
|
US20130261003A1
(en)
|
2010-08-06 |
2013-10-03 |
Ariosa Diagnostics, In. |
Ligation-based detection of genetic variants
|
|
US10533223B2
(en)
|
2010-08-06 |
2020-01-14 |
Ariosa Diagnostics, Inc. |
Detection of target nucleic acids using hybridization
|
|
US20120034603A1
(en)
|
2010-08-06 |
2012-02-09 |
Tandem Diagnostics, Inc. |
Ligation-based detection of genetic variants
|
|
MX349568B
(es)
|
2010-11-30 |
2017-08-03 |
Univ Hong Kong Chinese |
Deteccion de aberraciones geneticas o moleculares asociadas con el cancer.
|
|
US11270781B2
(en)
|
2011-01-25 |
2022-03-08 |
Ariosa Diagnostics, Inc. |
Statistical analysis for non-invasive sex chromosome aneuploidy determination
|
|
US9994897B2
(en)
|
2013-03-08 |
2018-06-12 |
Ariosa Diagnostics, Inc. |
Non-invasive fetal sex determination
|
|
US10131947B2
(en)
|
2011-01-25 |
2018-11-20 |
Ariosa Diagnostics, Inc. |
Noninvasive detection of fetal aneuploidy in egg donor pregnancies
|
|
US8756020B2
(en)
|
2011-01-25 |
2014-06-17 |
Ariosa Diagnostics, Inc. |
Enhanced risk probabilities using biomolecule estimations
|
|
WO2012149339A2
(en)
|
2011-04-29 |
2012-11-01 |
Sequenom, Inc. |
Quantification of a minority nucleic acid species
|
|
US8712697B2
(en)
|
2011-09-07 |
2014-04-29 |
Ariosa Diagnostics, Inc. |
Determination of copy number variations using binomial probability calculations
|
|
US10424394B2
(en)
|
2011-10-06 |
2019-09-24 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
WO2013060762A1
(en)
*
|
2011-10-25 |
2013-05-02 |
Roche Diagnostics Gmbh |
Method for diagnosing a disease based on plasma-dna distribution
|
|
HK1206055A1
(en)
|
2012-03-02 |
2015-12-31 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US9892230B2
(en)
*
|
2012-03-08 |
2018-02-13 |
The Chinese University Of Hong Kong |
Size-based analysis of fetal or tumor DNA fraction in plasma
|
|
JP6411995B2
(ja)
*
|
2012-03-13 |
2018-10-24 |
ザ チャイニーズ ユニバーシティー オブ ホンコン |
非侵襲的出生前診断のために大量並列シークエンシング・データを分析する方法
|
|
US10289800B2
(en)
|
2012-05-21 |
2019-05-14 |
Ariosa Diagnostics, Inc. |
Processes for calculating phased fetal genomic sequences
|
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
|
US10504613B2
(en)
|
2012-12-20 |
2019-12-10 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US11261494B2
(en)
|
2012-06-21 |
2022-03-01 |
The Chinese University Of Hong Kong |
Method of measuring a fractional concentration of tumor DNA
|
|
US20140093873A1
(en)
|
2012-07-13 |
2014-04-03 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
JP2015522293A
(ja)
|
2012-07-19 |
2015-08-06 |
アリオサ ダイアグノスティックス インコーポレイテッドＡｒｉｏｓａ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． |
多重化連続ライゲーションに基づく遺伝子変異体の検出
|
|
GB201215449D0
(en)
*
|
2012-08-30 |
2012-10-17 |
Zoragen Biotechnologies Llp |
Method of detecting chromosonal abnormalities
|
|
BR122021021823B1
(pt)
|
2012-09-20 |
2023-04-25 |
The Chinese University Of Hong Kong |
Método para determinar um primeiro perfil de metilação de uma amostra biológica de um organismo, e, meio de armazenamento de memória
|
|
US10482994B2
(en)
|
2012-10-04 |
2019-11-19 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
HK1216655A1
(zh)
|
2013-03-13 |
2016-11-25 |
Sequenom, Inc. |
用於dna甲基化分析的引物
|
|
TWI637058B
(zh)
|
2013-03-15 |
2018-10-01 |
香港中文大學 |
測定多胞胎妊娠之胎兒基因組
|
|
CN112037860B
(zh)
*
|
2013-06-13 |
2024-02-23 |
豪夫迈·罗氏有限公司 |
用于非入侵性性染色体非整倍性确定的统计分析
|
|
HUE042654T2
(hu)
*
|
2013-06-21 |
2019-07-29 |
Sequenom Inc |
Eljárás genetikai variációk nem-invazív megállapítására
|
|
KR102429186B1
(ko)
|
2013-10-21 |
2022-08-03 |
베리나타 헬스, 인코포레이티드 |
사본수 변동을 결정함에 있어서 검출의 감수성을 향상시키기 위한 방법
|
|
US11365447B2
(en)
|
2014-03-13 |
2022-06-21 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
CA2950596C
(en)
|
2014-05-30 |
2023-10-31 |
Verinata Health, Inc. |
Detecting fetal sub-chromosomal aneuploidies and copy number variations
|
|
AU2015269103B2
(en)
|
2014-06-06 |
2021-12-23 |
Cornell University |
Method for identification and enumeration of nucleic acid sequence, expression, copy, or DNA methylation changes, using combined nuclease, ligase, polymerase, and sequencing reactions
|
|
ES2741400T3
(es)
|
2014-07-18 |
2020-02-10 |
Univ Hong Kong Chinese |
Análisis de patrones de metilación de tejidos en mezcla de ADN
|
|
CN107002122B
(zh)
|
2014-07-25 |
2023-09-19 |
华盛顿大学 |
确定导致无细胞dna的产生的组织和/或细胞类型的方法以及使用其鉴定疾病或紊乱的方法
|
|
EP3175236B1
(en)
*
|
2014-08-01 |
2019-08-21 |
Ariosa Diagnostics, Inc. |
Detection of target nucleic acids using hybridization
|
|
EP3502273B1
(en)
|
2014-12-12 |
2020-07-08 |
Verinata Health, Inc. |
Cell-free dna fragment
|
|
US11242559B2
(en)
|
2015-01-13 |
2022-02-08 |
The Chinese University Of Hong Kong |
Method of nuclear DNA and mitochondrial DNA analysis
|
|
US10364467B2
(en)
|
2015-01-13 |
2019-07-30 |
The Chinese University Of Hong Kong |
Using size and number aberrations in plasma DNA for detecting cancer
|
|
US10319463B2
(en)
*
|
2015-01-23 |
2019-06-11 |
The Chinese University Of Hong Kong |
Combined size- and count-based analysis of maternal plasma for detection of fetal subchromosomal aberrations
|
|
EP3256605B1
(en)
|
2015-02-10 |
2022-02-09 |
The Chinese University Of Hong Kong |
Detecting mutations for cancer screening and fetal analysis
|
|
CN104789686B
(zh)
*
|
2015-05-06 |
2018-09-07 |
浙江安诺优达生物科技有限公司 |
检测染色体非整倍性的试剂盒和装置
|
|
PL3666902T3
(pl)
|
2015-05-22 |
2025-02-03 |
Medicover Public Co Ltd |
Multipleksowa równoległa analiza docelowych regionów genomowych do nieinwazyjnych badań prenatalnych
|
|
EP4063517B1
(en)
|
2015-07-20 |
2026-01-07 |
The Chinese University Of Hong Kong |
Methylation pattern analysis of haplotypes in cell-free dna mixtures of maternal and fetal dna
|
|
IL305462A
(en)
|
2015-07-23 |
2023-10-01 |
Univ Hong Kong Chinese |
DNA fragmentation pattern analysis suitable clean
|
|
CA2995422A1
(en)
|
2015-08-12 |
2017-02-16 |
The Chinese University Of Hong Kong |
Single-molecule sequencing of plasma dna
|
|
US10095831B2
(en)
|
2016-02-03 |
2018-10-09 |
Verinata Health, Inc. |
Using cell-free DNA fragment size to determine copy number variations
|
|
KR20190017738A
(ko)
*
|
2016-04-11 |
2019-02-20 |
퀀텀 바이오시스템즈 가부시키가이샤 |
생물학적 데이터 관리를 위한 시스템 및 방법
|
|
EP3518974A4
(en)
|
2016-09-29 |
2020-05-27 |
Myriad Women's Health, Inc. |
NON-INVASIVE PRENATAL SCREENING USING DYNAMIC ITERATIVE DEEP OPTIMIZATION
|
|
EP4209598A1
(en)
|
2016-10-19 |
2023-07-12 |
The Chinese University of Hong Kong |
Gestational age assessment by methylation and size profiling of maternal plasma dna
|
|
TWI797095B
(zh)
|
2016-10-24 |
2023-04-01 |
美商格瑞爾有限責任公司 |
腫瘤檢測之方法及系統
|
|
CN106591451B
(zh)
*
|
2016-12-14 |
2020-06-23 |
北京贝瑞和康生物技术有限公司 |
测定胎儿游离dna含量的方法及其用于实施该方法的装置
|
|
EP4421489B1
(en)
|
2017-01-25 |
2026-03-11 |
The Chinese University of Hong Kong |
Diagnostic applications using nucleic acid fragments
|
|
JP7370862B2
(ja)
|
2017-03-17 |
2023-10-30 |
セクエノム， インコーポレイテッド |
遺伝子モザイク症のための方法およびプロセス
|
|
CN110914456A
(zh)
*
|
2017-03-31 |
2020-03-24 |
普莱梅沙有限公司 |
检测胎儿染色体异常的方法
|
|
US11342047B2
(en)
|
2017-04-21 |
2022-05-24 |
Illumina, Inc. |
Using cell-free DNA fragment size to detect tumor-associated variant
|
|
IL316163A
(en)
|
2017-07-26 |
2024-12-01 |
Univ Hong Kong Chinese |
Enhancement of cancer screening using cell-free viral nucleic acids
|
|
US11168356B2
(en)
|
2017-11-02 |
2021-11-09 |
The Chinese University Of Hong Kong |
Using nucleic acid size range for noninvasive cancer detection
|
|
CN108827887B
(zh)
*
|
2018-03-19 |
2021-05-18 |
陕西学前师范学院 |
一种商陆基因组大小估计方法及基因组大小测量系统
|
|
KR20210014111A
(ko)
|
2018-05-03 |
2021-02-08 |
더 차이니즈 유니버시티 오브 홍콩 |
세포-무함유 혼합물의 특성을 측정하기 위한 크기-태깅된 바람직한 말단 및 배향-인지 분석
|
|
WO2020192680A1
(en)
|
2019-03-25 |
2020-10-01 |
The Chinese University Of Hong Kong |
Determining linear and circular forms of circulating nucleic acids
|
|
CA3147613A1
(en)
*
|
2019-08-19 |
2021-02-25 |
Chang-Seok Ki |
Method for detecting chromosomal abnormality by using information about distance between nucleic acid fragments
|
|
BR112022015073A2
(pt)
|
2020-02-05 |
2022-11-16 |
Univ Hong Kong Chinese |
Método de análise de uma amostra biológica, produto de programa de computador, mídia de armazenamento, e, sistema de computação
|