JP2013509360A5 - - Google Patents

Download PDF

Info

Publication number
JP2013509360A5
JP2013509360A5 JP2012535616A JP2012535616A JP2013509360A5 JP 2013509360 A5 JP2013509360 A5 JP 2013509360A5 JP 2012535616 A JP2012535616 A JP 2012535616A JP 2012535616 A JP2012535616 A JP 2012535616A JP 2013509360 A5 JP2013509360 A5 JP 2013509360A5
Authority
JP
Japan
Prior art keywords
taxol
steroid
complex according
organic solvent
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012535616A
Other languages
English (en)
Japanese (ja)
Other versions
JP6158513B2 (ja
JP2013509360A (ja
Filing date
Publication date
Priority claimed from CN200910236960.7A external-priority patent/CN102048725B/zh
Application filed filed Critical
Publication of JP2013509360A publication Critical patent/JP2013509360A/ja
Publication of JP2013509360A5 publication Critical patent/JP2013509360A5/ja
Application granted granted Critical
Publication of JP6158513B2 publication Critical patent/JP6158513B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012535616A 2009-10-29 2010-10-28 タクソール/ステロイド化合物 Active JP6158513B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN200910236960.7A CN102048725B (zh) 2009-10-29 2009-10-29 紫杉醇胆固醇复合物
CN200910236960.7 2009-10-29
PCT/CN2010/078202 WO2011050735A1 (zh) 2009-10-29 2010-10-28 紫杉醇/类固醇复合物

Publications (3)

Publication Number Publication Date
JP2013509360A JP2013509360A (ja) 2013-03-14
JP2013509360A5 true JP2013509360A5 (https=) 2017-01-12
JP6158513B2 JP6158513B2 (ja) 2017-07-12

Family

ID=43921347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012535616A Active JP6158513B2 (ja) 2009-10-29 2010-10-28 タクソール/ステロイド化合物

Country Status (9)

Country Link
US (1) US20130150335A1 (https=)
EP (1) EP2494956A4 (https=)
JP (1) JP6158513B2 (https=)
KR (1) KR20120091258A (https=)
CN (2) CN102048725B (https=)
AU (1) AU2010312017B2 (https=)
BR (1) BR112012010149A2 (https=)
CA (1) CA2779316C (https=)
WO (1) WO2011050735A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102048688B (zh) * 2009-10-29 2014-03-05 中国医学科学院药物研究所 以胆固醇复合物为中间载体的紫杉醇亚微乳
EP2679225A1 (de) * 2012-06-26 2014-01-01 Universitätsklinikum Freiburg Pharmazeutische Zusammensetzung mit synergistischer Wirkung von direkten Katalaseinhibitoren und zur Katalasezerstörung führenden Modulatoren des NO-Stoffwechsels oder der extrazellulären Superoxidanionenproduktion
US11273105B2 (en) * 2017-06-16 2022-03-15 Sorse Technology Corporation Method for preparing solid forms of plant extract
CN108272747B (zh) * 2018-03-16 2020-02-18 武汉百纳礼康生物制药有限公司 一种非那雄胺溶致液晶凝胶制剂前体及其制备方法
KR20210078505A (ko) 2018-10-16 2021-06-28 유에스 나노 푸드 앤 드럭 인코포레이티드 종양내 주사 제형
WO2021211294A1 (en) 2020-04-13 2021-10-21 US Nano Food & Drug INC Basic chemotherapeutic intratumour injection formulation
KR102789632B1 (ko) * 2021-04-01 2025-04-01 에스엔제이 파마 인크 생활성물질의 경구용 나노입자 및 이의 제조방법
CN115177589B (zh) * 2021-04-07 2024-02-06 中国医学科学院药物研究所 一种紫杉醇脑靶向脂质体和其制备方法及应用
CN115463110B (zh) * 2021-06-10 2023-12-15 中国医学科学院药物研究所 一种胆酸修饰的口服紫杉醇纳米粒、其制备方法及应用
CN115737654B (zh) * 2021-09-03 2025-11-21 成都瑞沐生物医药科技有限公司 一种滴眼给药预防和/或治疗白内障的眼用制剂
CN116196283A (zh) * 2021-11-30 2023-06-02 深圳玖星制药有限公司 一种注射用紫杉烷类药物脂质体冻干粉剂的制备方法及原料组方
CN117482052A (zh) * 2023-11-29 2024-02-02 中国药科大学 一种口服紫杉醇三元递药系统及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
CN1116875C (zh) * 2000-10-19 2003-08-06 南京振中生物工程有限公司 紫杉醇脂质组合物及其制备方法
US20090110739A1 (en) * 2007-05-15 2009-04-30 University Of North Texas Health Science Center At Forth Worth Targeted cancer chemotherapy using synthetic nanoparticles
CN101396343B (zh) * 2007-09-26 2011-12-07 中国医学科学院药物研究所 以脂质复合物为中间载体的紫杉醇亚微乳
CN102048688B (zh) * 2009-10-29 2014-03-05 中国医学科学院药物研究所 以胆固醇复合物为中间载体的紫杉醇亚微乳

Similar Documents

Publication Publication Date Title
JP2013509360A5 (https=)
Hanson Steroids: partial synthesis in medicinal chemistry
JP5918170B2 (ja) Cns疾患治療用医薬組成物の製造のためのプレグナンおよびアンドロスタンステロイドの使用
CN101522703B (zh) 胆酸派生物及其在制备预防或治疗fxr介导的疾病或状况的药物中的应用
CN104721160B (zh) 一种醋酸泼尼松片剂及其制备方法
JP2010510210A5 (https=)
JP2011522836A (ja) 17−アルキニル−7−ヒドロキシステロイドおよび関連する化合物の調製方法
CN110028547B (zh) 一种薯蓣皂苷元3-oh衍生物及其制备方法和医药用途
CN105348351B (zh) 制备甲基四烯物的方法
CN105143241A (zh) 用于制备固体形式的乙酸阿比特龙的方法
CN102532246B (zh) 一种齐墩果酸衍生物及其制备方法和应用
CN102558256B (zh) 从远志中分离制备细叶远志皂苷的方法
DE2529521C2 (de) Verfahren zur Gewinnung von 3-Hydroxysteroiden und 3-Oxosteroiden
CH630334A5 (de) Verfahren zur herstellung von carbonsaeureestern.
JP2011511823A5 (https=)
Wang et al. First synthesis of 22-oxa-chenodeoxycholic acid analogue
CN104059118B (zh) 立体选择性一步还原甾体骨架中的4-烯-3-酮为3α-羟基-5β-氢A/B顺式结构的方法
CN102885061A (zh) β-环糊精包合的甾体类植物生长激素可湿粉的制备方法
EP2506855A1 (en) Anticancer compounds and screening method
EP0875515B1 (en) Sulfatation of estrogen mixtures
CN113501854B (zh) 一种从蛞蝓中制备胆甾醇基十七酸酯的方法
Reyes-Moreno et al. Synthesis and anabolic/androgenic evaluation of novel 9α-fluorosteroids
DE1643010A1 (de) Verfahren zur Herstellung von 17alpha-Alkinyl-17ss-alkanoyloxy-Steroiden der Andostran- und Oestranreihe
Morzycki et al. 13C NMR study of spirostanes and furostanes in solution and solid state
CN104974209B (zh) 一种17,21‑双羟基甾体衍生物的合成方法