JP2013509168A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013509168A5 JP2013509168A5 JP2012535849A JP2012535849A JP2013509168A5 JP 2013509168 A5 JP2013509168 A5 JP 2013509168A5 JP 2012535849 A JP2012535849 A JP 2012535849A JP 2012535849 A JP2012535849 A JP 2012535849A JP 2013509168 A5 JP2013509168 A5 JP 2013509168A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- expression cassette
- vector
- seq
- acid expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09174519 | 2009-10-29 | ||
| EP09174519.0 | 2009-10-29 | ||
| PCT/EP2010/066474 WO2011051450A1 (en) | 2009-10-29 | 2010-10-29 | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013509168A JP2013509168A (ja) | 2013-03-14 |
| JP2013509168A5 true JP2013509168A5 (https=) | 2013-12-19 |
| JP5823969B2 JP5823969B2 (ja) | 2015-11-25 |
Family
ID=43414855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012535849A Expired - Fee Related JP5823969B2 (ja) | 2009-10-29 | 2010-10-29 | 心臓特異的核酸調節因子ならびにこの方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9353164B2 (https=) |
| EP (1) | EP2494058B1 (https=) |
| JP (1) | JP5823969B2 (https=) |
| AU (1) | AU2010311376B2 (https=) |
| CA (1) | CA2778945A1 (https=) |
| WO (1) | WO2011051450A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011051450A1 (en) | 2009-10-29 | 2011-05-05 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
| US8859517B2 (en) | 2011-08-08 | 2014-10-14 | Fondazione Salvatore Maugeri Clinica Del Lavoro E Della Riabilitazione | Method of gene transfer for the treatment of recessive catecholaminergic polymorphic ventricular tachycardia (CPVT) |
| US20130136729A1 (en) * | 2011-11-11 | 2013-05-30 | University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group | Compositions and methods for targeting and treating diseases and injuries using adeno-associated virus vectors |
| WO2014077863A1 (en) * | 2012-11-19 | 2014-05-22 | Nature Technology Corporation | Replicative minicircle vectors with improved expression |
| JP6707028B2 (ja) | 2013-12-09 | 2020-06-10 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 心筋細胞新生におけるｈｉｐｐｏ及びジストロフィン複合体シグナル伝達 |
| PL3097197T3 (pl) | 2014-01-21 | 2021-06-28 | Vrije Universiteit Brussel | Mięśniowo-specyficzne elementy regulatorowe kwasów nukleinowych oraz sposoby i ich zastosowanie |
| US10570183B2 (en) * | 2016-04-19 | 2020-02-25 | The Board Of Regents Of The University Of Texas System | Use of a small native peptide activator of SERCA pump for treatment of heart failure and other disorders characterized by cytosolic calcium overload |
| WO2018178067A1 (en) | 2017-03-27 | 2018-10-04 | Vrije Universiteit Brussel | Diaphragm-specific nucleic acid regulatory elements and methods and use thereof |
| US20210343368A1 (en) * | 2018-09-05 | 2021-11-04 | Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft | Method for Engineering Synthetic Cis-Regulatory DNA |
| JP7529286B2 (ja) | 2018-10-26 | 2024-08-06 | フリーイェ・ユニヴェルシテイト・ブリュッセル | 肝特異的核酸調節エレメント並びにその方法及び使用 |
| EP4073257A1 (en) * | 2019-12-09 | 2022-10-19 | UCL Business Ltd | Gene therapy composition and treatment for myh7-linked cardiomyopathy |
| EP4081643A1 (en) * | 2019-12-24 | 2022-11-02 | Asklepios Biopharmaceutical, Inc. | Regulatory nucleic acid sequences |
| EP4087489B1 (en) | 2020-01-08 | 2025-05-14 | Vitruvia Holdings Inc. | Methods and computing system for processing ultrasound image to determine health of subdermal tissue |
| JP7744027B2 (ja) | 2020-02-18 | 2025-09-25 | フレイエ ユニヴェルシテイト ブリュッセル | 核酸調節エレメントの新規な組合せ並びにその方法及び使用 |
| JP2024502257A (ja) * | 2020-12-21 | 2024-01-18 | フレイエ ユニヴェルシテイト ブリュッセル | 心筋細胞由来核酸調節エレメント並びにその方法及び使用 |
| KR20240032971A (ko) | 2021-07-08 | 2024-03-12 | 테나야 테라퓨틱스, 인코포레이티드 | 유전자 요법을 위한 최적화된 발현 카세트 |
| AR126660A1 (es) | 2021-07-28 | 2023-11-01 | Univ Brussel Vrije | Mejorando la eficacia de la terapia génica dirigida a músculos |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2797273B1 (fr) | 1999-08-06 | 2004-01-02 | Pasteur Institut | Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique |
| JP2003530086A (ja) | 2000-01-14 | 2003-10-14 | ベス イスラエル ディーコネス メディカル センター | 心臓細胞特異的エンハンサー因子とその使用 |
| ATE373095T1 (de) * | 2000-07-14 | 2007-09-15 | Univ Michigan | Mutierte muskelspezifische enhancer |
| US20050004058A1 (en) * | 2000-12-07 | 2005-01-06 | Patrick Benoit | Sequences upstream of the carp gene, vectors containing them and uses thereof |
| US7714100B2 (en) * | 2004-01-27 | 2010-05-11 | Compugen Ltd | Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease |
| BRPI0513897A (pt) * | 2004-07-29 | 2008-05-20 | Stem Cell Innovations Inc | diferenciação de células-tronco |
| US20080081354A1 (en) * | 2006-10-02 | 2008-04-03 | Cardiac Pacemakers, Inc. | Devices, vectors and methods for inducible ischemia cardioprotection |
| WO2008054713A2 (en) | 2006-10-30 | 2008-05-08 | Thomas Jefferson University | Tissue specific gene therapy treatment |
| US20110027234A1 (en) * | 2007-04-11 | 2011-02-03 | Technion Research & Development Foundation Ltd. | Methods for identification and selection of human embryonic stem cell derived cells |
| CA2722238C (en) | 2008-04-22 | 2017-11-28 | Life Sciences Research Partners Vzw | Liver-specific nucleic acid regulatory elements and methods and use thereof |
| WO2011051450A1 (en) | 2009-10-29 | 2011-05-05 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
-
2010
- 2010-10-29 WO PCT/EP2010/066474 patent/WO2011051450A1/en not_active Ceased
- 2010-10-29 US US13/504,614 patent/US9353164B2/en not_active Expired - Fee Related
- 2010-10-29 AU AU2010311376A patent/AU2010311376B2/en not_active Ceased
- 2010-10-29 JP JP2012535849A patent/JP5823969B2/ja not_active Expired - Fee Related
- 2010-10-29 CA CA2778945A patent/CA2778945A1/en not_active Abandoned
- 2010-10-29 EP EP10771459.4A patent/EP2494058B1/en not_active Not-in-force
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013509168A5 (https=) | ||
| JP2015521465A5 (https=) | ||
| JP2021505133A5 (https=) | ||
| US9353164B2 (en) | Cardiac-specific nucleic acid regulatory elements and methods and use thereof | |
| JP2020518268A5 (https=) | ||
| ITTO20130669A1 (it) | Vettore adeno-associato ricombinante muscolo-specifico e suo impiego nel trattamento di patologie muscolari | |
| JP2020054367A (ja) | 改変ｇ６ｐｃをコードするアデノ随伴ウイルスベクターおよびその使用 | |
| IL316189A (en) | Treatment of complement-mediated disorders | |
| JP2013518599A5 (https=) | ||
| CN111235158B (zh) | 用于表达重组人β-珠蛋白的病毒载体及其应用 | |
| TW202421787A (zh) | 保護心臟之心臟病療法 | |
| WO2014036524A4 (en) | Genetically modified msc and therapeutic methods | |
| AU2021358413B2 (en) | Nucleic acid constructs, viral vectors and viral particles | |
| US20240350666A1 (en) | Compositions and methods for high efficiency genome editing | |
| WO2023147558A2 (en) | Crispr methods for correcting bag3 gene mutations in vivo | |
| JP6473438B2 (ja) | プロモーター組成物 | |
| JP2016512028A5 (https=) | ||
| US20260027236A1 (en) | Guide rnas, vectors, and virions for targeting mutations in the pln gene | |
| Lai et al. | Design of muscle gene therapy expression cassette | |
| AU2014240247B2 (en) | Cardiac-specific nucleic acid regulatory elements and methods and use thereof | |
| Ryu et al. | Activation of the LMO2 gene in human lymphoid cells by targeted insertion of a single retroviral LTR expression cassette into the first intron | |
| NZ761706A (en) | Compositions useful in treatment of ornithine transcarbamylase (otc) deficiency | |
| RU2013148606A (ru) | Универсальный промотор для экспрессии терапевтических генов в клетках млекопитающих | |
| NZ761706B2 (en) | Compositions useful in treatment of ornithine transcarbamylase (otc) deficiency | |
| HK1220486B (en) | Promoter compositions |