JP2013508400A5 - - Google Patents

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Publication number
JP2013508400A5
JP2013508400A5 JP2012535373A JP2012535373A JP2013508400A5 JP 2013508400 A5 JP2013508400 A5 JP 2013508400A5 JP 2012535373 A JP2012535373 A JP 2012535373A JP 2012535373 A JP2012535373 A JP 2012535373A JP 2013508400 A5 JP2013508400 A5 JP 2013508400A5
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JP
Japan
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composition
weeks
days
cancer
administered
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Withdrawn
Application number
JP2012535373A
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English (en)
Japanese (ja)
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JP2013508400A (ja
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Priority claimed from PCT/US2010/053579 external-priority patent/WO2011050180A1/en
Publication of JP2013508400A publication Critical patent/JP2013508400A/ja
Publication of JP2013508400A5 publication Critical patent/JP2013508400A5/ja
Withdrawn legal-status Critical Current

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JP2012535373A 2009-10-21 2010-10-21 新規な投与レジメンおよび治療法 Withdrawn JP2013508400A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25380409P 2009-10-21 2009-10-21
US61/253,804 2009-10-21
PCT/US2010/053579 WO2011050180A1 (en) 2009-10-21 2010-10-21 Novel dosing regimen and method of treatment

Publications (2)

Publication Number Publication Date
JP2013508400A JP2013508400A (ja) 2013-03-07
JP2013508400A5 true JP2013508400A5 (https=) 2013-12-05

Family

ID=43898626

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012535373A Withdrawn JP2013508400A (ja) 2009-10-21 2010-10-21 新規な投与レジメンおよび治療法

Country Status (13)

Country Link
US (1) US20110097345A1 (https=)
EP (1) EP2490715A4 (https=)
JP (1) JP2013508400A (https=)
KR (1) KR20120094472A (https=)
CN (1) CN102630165A (https=)
AU (1) AU2010310577A1 (https=)
BR (1) BR112012009250A2 (https=)
CA (1) CA2775806A1 (https=)
IL (1) IL219279A0 (https=)
IN (1) IN2012DN02826A (https=)
MX (1) MX2012004406A (https=)
RU (1) RU2012120691A (https=)
WO (1) WO2011050180A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
EP2526118A4 (en) * 2010-01-21 2013-11-13 Immunogen Inc COMPOSITIONS AND METHOD FOR THE TREATMENT OF EGG CANCER
EP2524929A1 (en) 2011-05-17 2012-11-21 Sanofi Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
WO2014018563A2 (en) * 2012-07-23 2014-01-30 The Board Of Trustees Of The Leland Stanford Junior University Methods for the treatment of cancer
WO2014052876A1 (en) * 2012-09-28 2014-04-03 Immunogen Inc. Methods for increasing efficacy of cd56- based therapy
WO2014089177A2 (en) 2012-12-04 2014-06-12 Massachusetts Institute Of Technology Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
CA2911499A1 (en) * 2013-05-14 2014-11-20 Immunogen, Inc. Anti-folr1 immunoconjugate dosing regimens
IL298044B2 (en) * 2013-10-08 2024-11-01 Immunogen Inc Dosing regimens of anti-FOLR1 immunoconjugate
ES3012974T3 (en) * 2014-01-08 2025-04-10 Univ Leland Stanford Junior Targeted therapy for lung cancer
EP3160513B1 (en) 2014-06-30 2020-02-12 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
US10918627B2 (en) 2016-05-11 2021-02-16 Massachusetts Institute Of Technology Convergent and enantioselective total synthesis of Communesin analogs
IL303436A (en) * 2016-08-10 2023-08-01 Celgene Quanticel Res Inc Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas
AU2017360346B2 (en) 2016-11-21 2023-11-23 Eirion Therapeutics, Inc. Transdermal delivery of large agents
WO2018209239A1 (en) 2017-05-11 2018-11-15 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
SG11202012257VA (en) * 2018-06-26 2021-01-28 Immunogen Inc Immunoconjugates targeting adam9 and methods of use thereof
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
TW202210104A (zh) * 2020-06-04 2022-03-16 瑞典商生物創新國際有限公司 皮下抗體調配物
WO2022182415A1 (en) 2021-02-24 2022-09-01 Massachusetts Institute Of Technology Himastatin derivatives, and processes of preparation thereof, and uses thereof
EP4709485A1 (en) * 2023-05-10 2026-03-18 Legend Biotech Ireland Limited Chimeric antigen receptors and methods of use thereof
CN120053673A (zh) * 2025-02-11 2025-05-30 暨南大学 纳米前药及其制备方法和用途
CN120173115A (zh) * 2025-05-20 2025-06-20 苏州欣协生物科技有限公司 一种抗人cd56蛋白工程抗体及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208020A (en) * 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
US5639641A (en) * 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US7303749B1 (en) * 1999-10-01 2007-12-04 Immunogen Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
AU775373B2 (en) * 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IL159422A0 (en) * 2001-09-20 2004-06-01 Cornell Res Foundation Inc Methods and compositions for treating or preventing skin disorders using binding agents specific for prostate-specific membrane antigen
US20040126379A1 (en) * 2002-08-21 2004-07-01 Boehringer Ingelheim International Gmbh Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents
KR101424624B1 (ko) * 2003-05-14 2014-07-31 이뮤노젠 아이엔씨 약물 콘쥬게이트 조성물
CA2525987A1 (en) * 2003-06-05 2005-01-06 Charles Achkar Methods of treating hyperproliferative cell disorders
US8101720B2 (en) * 2004-10-21 2012-01-24 Xencor, Inc. Immunoglobulin insertions, deletions and substitutions
ZA200708694B (en) * 2005-04-15 2009-01-28 Immunogen Inc Elimination of heterogeneous or mixed cell population in tumors
EP3569245A1 (en) * 2006-09-26 2019-11-20 Genmab A/S Combination treatment of cd38-expressing tumors
WO2010008726A1 (en) * 2008-06-16 2010-01-21 Immunogen Inc. Novel synergistic effects
EP2526118A4 (en) * 2010-01-21 2013-11-13 Immunogen Inc COMPOSITIONS AND METHOD FOR THE TREATMENT OF EGG CANCER
AU2012240448A1 (en) * 2011-04-01 2013-03-28 Immunogen, Inc. Compositions and methods for treatment of ovarian, peritoneal, and fallopian tube cancer

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