JP2014505056A5 - - Google Patents

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Publication number
JP2014505056A5
JP2014505056A5 JP2013548613A JP2013548613A JP2014505056A5 JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5 JP 2013548613 A JP2013548613 A JP 2013548613A JP 2013548613 A JP2013548613 A JP 2013548613A JP 2014505056 A5 JP2014505056 A5 JP 2014505056A5
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JP
Japan
Prior art keywords
antibody
tlr4
immunologically active
active fragment
amino acid
Prior art date
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Application number
JP2013548613A
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English (en)
Japanese (ja)
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JP6289098B2 (ja
JP2014505056A (ja
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Priority claimed from PCT/US2012/020717 external-priority patent/WO2012096917A1/en
Publication of JP2014505056A publication Critical patent/JP2014505056A/ja
Publication of JP2014505056A5 publication Critical patent/JP2014505056A5/ja
Application granted granted Critical
Publication of JP6289098B2 publication Critical patent/JP6289098B2/ja
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JP2013548613A 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法 Active JP6289098B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161431191P 2011-01-10 2011-01-10
US61/431,191 2011-01-10
PCT/US2012/020717 WO2012096917A1 (en) 2011-01-10 2012-01-10 Anti-tlr4 antibodies and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017027473A Division JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法

Publications (3)

Publication Number Publication Date
JP2014505056A JP2014505056A (ja) 2014-02-27
JP2014505056A5 true JP2014505056A5 (https=) 2015-02-26
JP6289098B2 JP6289098B2 (ja) 2018-03-07

Family

ID=46455425

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013548613A Active JP6289098B2 (ja) 2011-01-10 2012-01-10 抗ｔｌｒ４抗体およびその使用法
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017027473A Pending JP2017137319A (ja) 2011-01-10 2017-02-17 抗ｔｌｒ４抗体およびその使用法
JP2019035074A Pending JP2019081796A (ja) 2011-01-10 2019-02-28 抗ｔｌｒ４抗体およびその使用法

Country Status (7)

Country Link
US (4) US8734790B2 (https=)
EP (2) EP3539987A1 (https=)
JP (3) JP6289098B2 (https=)
AU (2) AU2012205763B2 (https=)
CA (1) CA2824060C (https=)
ES (1) ES2721378T3 (https=)
WO (1) WO2012096917A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2173381T1 (sl) * 2007-05-14 2014-01-31 Novimmune Sa Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami
WO2012096917A1 (en) * 2011-01-10 2012-07-19 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
EP2831117B1 (en) * 2012-03-29 2017-11-01 NovImmune SA Anti-tlr4 antibodies and uses thereof
WO2015059168A1 (en) 2013-10-22 2015-04-30 Novimmune S.A. Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers
WO2015082716A1 (en) * 2013-12-06 2015-06-11 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof
US20170038381A1 (en) * 2015-08-06 2017-02-09 Novimmune Sa Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders
WO2017160599A1 (en) 2016-03-14 2017-09-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of cd300b antagonists to treat sepsis and septic shock
CN109481666B (zh) * 2018-12-21 2020-11-03 江苏省中医院 一种人体血液肿瘤pdx模型的建立方法
EP4138912A4 (en) * 2020-04-20 2024-08-07 Edesa Biotech Research Inc. COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME
WO2022112198A1 (en) 2020-11-24 2022-06-02 Worldwide Innovative Network Method to select the optimal immune checkpoint therapies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5151510A (en) 1990-04-20 1992-09-29 Applied Biosystems, Inc. Method of synethesizing sulfurized oligonucleotide analogs
US5624946A (en) * 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
CA2824167C (en) * 2002-09-06 2018-09-25 Amgen Inc. Therapeutic human anti-il-1r1 monoclonal antibody
US7312320B2 (en) 2003-12-10 2007-12-25 Novimmune Sa Neutralizing antibodies and methods of use thereof
EP1711531B9 (en) 2003-12-10 2012-07-25 Novimmune SA Neutralizing anti tlr4/md-2 antibodies and methods of use thereof
US7674884B2 (en) 2003-12-10 2010-03-09 Novimmune S.A. Neutralizing antibodies and methods of use thereof
DK2311873T3 (en) * 2004-01-07 2018-11-26 Novartis Vaccines & Diagnostics Inc M-CSF-SPECIFIC MONOCLONAL ANTIBODY AND APPLICATIONS THEREOF
EP1929032A4 (en) * 2005-09-30 2009-11-04 Oklahoma Med Res Found REGULATION OF GOOD LIKE RECEPTORS ON STEM CELLS
SI2173381T1 (sl) * 2007-05-14 2014-01-31 Novimmune Sa Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami
WO2009013848A1 (ja) 2007-07-24 2009-01-29 Panasonic Corporation ニッケル水素電池用負極材料とその処理方法およびニッケル水素電池
WO2009138494A2 (en) 2008-05-15 2009-11-19 Ablynx N.V. Amino acid sequences directed against toll-like receptors and polypeptides comprising the same for the treatment of diseases related to toll-like receptors
JP5685535B2 (ja) * 2008-08-18 2015-03-18 ファイザー インコーポレイティッド Ｃｃｒ２に対する抗体
WO2012096917A1 (en) * 2011-01-10 2012-07-19 Novimmune S.A. Anti-tlr4 antibodies and methods of use thereof

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