JP2013507922A5 - - Google Patents

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Publication number
JP2013507922A5
JP2013507922A5 JP2012534269A JP2012534269A JP2013507922A5 JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5 JP 2012534269 A JP2012534269 A JP 2012534269A JP 2012534269 A JP2012534269 A JP 2012534269A JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5
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JP
Japan
Prior art keywords
cell
cell culture
trough
micrometers
chamber
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2012534269A
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English (en)
Japanese (ja)
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JP2013507922A (ja
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Publication date
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Priority claimed from PCT/US2010/052212 external-priority patent/WO2011046884A2/en
Publication of JP2013507922A publication Critical patent/JP2013507922A/ja
Publication of JP2013507922A5 publication Critical patent/JP2013507922A5/ja
Abandoned legal-status Critical Current

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JP2012534269A 2009-10-12 2010-10-12 細胞培養用マイクロ流体デバイス Abandoned JP2013507922A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25075409P 2009-10-12 2009-10-12
US61/250,754 2009-10-12
PCT/US2010/052212 WO2011046884A2 (en) 2009-10-12 2010-10-12 Microfluidic device for cell culture

Publications (2)

Publication Number Publication Date
JP2013507922A JP2013507922A (ja) 2013-03-07
JP2013507922A5 true JP2013507922A5 (https=) 2013-05-30

Family

ID=43855151

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012534269A Abandoned JP2013507922A (ja) 2009-10-12 2010-10-12 細胞培養用マイクロ流体デバイス

Country Status (5)

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US (2) US8481303B2 (https=)
EP (1) EP2488628A2 (https=)
JP (1) JP2013507922A (https=)
CN (1) CN102612554A (https=)
WO (1) WO2011046884A2 (https=)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534601B2 (en) * 2002-08-27 2009-05-19 Vanderbilt University Capillary perfused bioreactors with multiple chambers
EP2358860A1 (en) * 2008-11-21 2011-08-24 Corning Incorporated Spaced projection substrates and devices for cell culture
JP5879267B2 (ja) * 2009-10-29 2016-03-08 ザ・チャールズ・スターク・ドレイパ・ラボラトリー・インコーポレイテッド 血液透析用マイクロ流体装置
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
CN102234614B (zh) * 2011-05-30 2013-02-13 中国科学院苏州纳米技术与纳米仿生研究所 微流控细胞悬浮培养芯片及其应用
KR101970634B1 (ko) 2011-06-02 2019-04-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 생체외 조직 배양 시스템을 위한 방법 및 용도
WO2012174460A1 (en) * 2011-06-15 2012-12-20 The Charles Stark Draper Laboratory, Inc. Systems, methods, and devices relating to a biomimetic cellularized nephron unit
JP2014516582A (ja) * 2011-06-15 2014-07-17 ザ チャールズ スターク ドレイパー ラボラトリー インク 生体模倣環境において細胞を培養するためのデバイスおよび方法
US10640807B2 (en) 2011-12-29 2020-05-05 S.D. Sight Diagnostics Ltd Methods and systems for detecting a pathogen in a biological sample
WO2014031523A2 (en) * 2012-08-19 2014-02-27 University Of Rochester Method for preparing microfluidic device with reduced channel height
US20140127733A1 (en) * 2012-11-01 2014-05-08 Moffit Cancer Center Ex vivo microfluidic analysis of biologic samples
EP2972313B1 (en) 2013-03-15 2018-01-03 Rinker, Kristina, D. Ported parallel plate flow chamber and methods for use thereof
EP2999988A4 (en) 2013-05-23 2017-01-11 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
EP3024921B1 (en) 2013-07-22 2025-12-10 The Regents of The University of California Microfluidics cell culture device
WO2015029032A1 (en) 2013-08-26 2015-03-05 Parasight Ltd. Digital microscopy systems, methods and computer program products
US20150064689A1 (en) * 2013-08-29 2015-03-05 The Charles Stark Draper Laboratory, Inc. System and method for analyzing transmissibility of influenza
CN103627635B (zh) * 2013-11-18 2015-05-20 辽宁中医药大学 一种用于细胞迁移和侵袭实验的多功能微流控芯片
US20150247112A1 (en) * 2014-03-03 2015-09-03 Kiyatec Inc. 3D Tissue Culture Devices and Systems
US9631167B2 (en) * 2014-03-21 2017-04-25 Iontox, Llc Dynamic multi organ plate
EP3177709B1 (en) 2014-08-07 2022-05-18 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Reversible stencils for fabricating micro-tissues
US10482595B2 (en) 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
CN104293666B (zh) * 2014-09-11 2016-06-22 大连理工大学 两种不同单细胞之间相互作用的微流控芯片装置
CN105713835B (zh) * 2014-12-05 2018-11-09 中国科学院大连化学物理研究所 一种基于微流控芯片的多功能区域细胞三维共培养方法
US10279345B2 (en) 2014-12-12 2019-05-07 Opko Diagnostics, Llc Fluidic systems comprising an incubation channel, including fluidic systems formed by molding
US10723988B2 (en) 2015-04-22 2020-07-28 Berkeley Lights, Inc. Microfluidic cell culture
GB201512600D0 (en) * 2015-07-17 2015-08-26 Koniku Ltd Cell culture, transport and investigation
US10488644B2 (en) 2015-09-17 2019-11-26 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
US10799865B2 (en) 2015-10-27 2020-10-13 Berkeley Lights, Inc. Microfluidic apparatus having an optimized electrowetting surface and related systems and methods
GB2560290B (en) 2015-12-04 2022-03-09 Emulate Inc Open-Top Microfluidic Device With Structural Anchors
US11744708B2 (en) * 2016-02-16 2023-09-05 Koninklijke Philips N.V. Surface topographies for altering the physiology of living cells
WO2017172638A1 (en) * 2016-03-29 2017-10-05 Smsbiotech, Inc. Compositions and methods for using small mobile stem cells
CA3018536A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinguishing between blood sample components
US11414635B2 (en) 2016-04-18 2022-08-16 Saint Louis University Integration of three dimensional cell culture scaffolds in microfluidic devices by direct fiber spinning
EP3455626B1 (en) 2016-05-11 2025-08-06 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
WO2017195205A1 (en) 2016-05-11 2017-11-16 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
IL263274B2 (en) 2016-05-26 2023-10-01 Berkeley Lights Inc Covalently adapted surfaces, kits and methods for their production and uses
CN105838606B (zh) * 2016-06-08 2018-10-02 牛海涛 一种高通量细胞联合培养芯片
US10243097B2 (en) * 2016-09-09 2019-03-26 eLux Inc. Fluidic assembly using tunable suspension flow
WO2018080308A2 (en) * 2016-10-28 2018-05-03 Materiomics B.V. Surface topographies for stimulating endothelialization
US11474103B2 (en) 2017-02-17 2022-10-18 Koniku Inc. Systems for detection
CA3055767A1 (en) * 2017-03-31 2018-10-04 Dana-Farber Cancer Institute, Inc. Methods for evaluating tumor cell spheroids using 3d microfluidic cell culture device
EP3606669A1 (en) 2017-04-03 2020-02-12 The Charles Stark Draper Laboratory, Inc. Microfluidic system for evaluation of chemotherapeutic and immunotherapeutic drugs
CN111788471B (zh) 2017-11-14 2023-12-12 思迪赛特诊断有限公司 用于光学测量的样品载体
KR101979145B1 (ko) * 2018-01-30 2019-05-15 서강대학교산학협력단 신경줄기세포 배양용 미세유체칩 및 이의 용도
WO2020081288A1 (en) * 2018-10-14 2020-04-23 Arizona Board Of Regents On Behalf Of Arizona State University Microfluidic devices and methods incorporating organized three-dimensional tissue constructs
KR102170851B1 (ko) * 2018-11-13 2020-10-27 엠비디 주식회사 세포 배양 플레이트
US12305153B2 (en) * 2019-05-13 2025-05-20 Newsouth Innovations Pty Limited Microfluidic device and method of use for cell culture
AU2020370212B2 (en) 2019-10-22 2025-09-25 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
CN114787625B (zh) 2019-12-12 2026-01-13 思迪赛特诊断有限公司 检测血液样品中的血小板
BR112022011312A2 (pt) 2019-12-12 2022-08-23 S D Sight Diagnostics Ltd Análise de um analito disposto dentro de um meio
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス.ディー.サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成
CN111068516B (zh) * 2020-01-18 2023-11-14 浙江大学 多元强化耦合智能调控防止高粘性灰在催化剂表面沉积的系统及方法
GB202002010D0 (en) * 2020-02-13 2020-04-01 Univ Of Nottingham Research Microtopographies and uses thereof
US20240034973A1 (en) * 2020-12-02 2024-02-01 Ushio Denki Kabushiki Kaisha Culture vessel, and method of using culture vessel
EP4281534A4 (en) * 2021-01-22 2024-03-13 Hewlett-Packard Development Company, L.P. MICROFLUIDIC DEVICE CHAMBER PILLARS
US20240299942A1 (en) * 2021-06-30 2024-09-12 Hewlett-Packard Development Company, L.P. Microfluidic device chamber pillars
CN114453039B (zh) * 2022-02-08 2025-09-30 浙江扬清芯片技术有限公司 一种离心式微流控芯片点阵阀结构
US12186748B2 (en) 2022-06-24 2025-01-07 Hewlett-Packard Development Company, L.P. Self-priming microfluidic structures
CN115742293A (zh) * 2022-11-01 2023-03-07 福建星海通信科技有限公司 一种基于dlp3d打印的生物应用微流体器件制备方法
CN121446571A (zh) * 2026-01-05 2026-02-03 四川迪亚生物科技集团有限公司 一种基于乏氧微环境的微流控芯片制备方法及其应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437404A (en) 1973-09-24 1976-05-26 Kaye S Method and means for assaying biological factors demonstrating quantal response
DE3275216D1 (en) 1981-09-18 1987-02-26 Bbc Brown Boveri & Cie Storage cavern for air under constant pressure with a hydraulic pressure compensation for a gas turbine power plant
DE4116727C2 (de) 1991-05-17 1995-09-07 Uwe Dr Marx Verfahren und Vorrichtung zur gleichzeitigen Kultivierung unterschiedlicher Säugerzellen
DE4132379A1 (de) 1991-09-28 1993-04-08 Kernforschungsz Karlsruhe Substrat fuer zellkulturen und kultur von zellen oder zellaggregaten
CA2175660C (en) 1993-11-02 2005-07-05 Charles S. Naiman Control of cell growth
FR2741357B1 (fr) 1995-11-22 1998-01-16 Corning Inc Procede de fabrication d'une plaquette de support d'un reseau bidimensionnel de micropuits, notamment pour essais ou cultures biologiques
US6391578B2 (en) 1997-04-09 2002-05-21 3M Innovative Properties Company Method and devices for partitioning biological sample liquids into microvolumes
CH692583A5 (de) 1998-03-03 2002-08-15 Weidmann H Ag Kulturgefäss.
GB9805214D0 (en) 1998-03-11 1998-05-06 Univ Glasgow Cell adhesion
WO1999047922A2 (en) 1998-03-18 1999-09-23 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
JP2000231007A (ja) 1999-02-09 2000-08-22 Ricoh Opt Ind Co Ltd 凹型微細形状のアレイ状パターン形成方法及びその形成方法を用いて製作される平板型レンズアレイ及び液晶表示素子及び平板型オイルトラップ
US7033821B2 (en) 2000-11-08 2006-04-25 Surface Logix, Inc. Device for monitoring cell motility in real-time
US7211209B2 (en) 2000-11-08 2007-05-01 Surface Logix, Inc. Method of making device for arraying biomolecules and for monitoring cell motility in real-time
US6653124B1 (en) 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
US7018418B2 (en) 2001-01-25 2006-03-28 Tecomet, Inc. Textured surface having undercut micro recesses in a surface
US7288405B2 (en) 2001-04-25 2007-10-30 Cornell Research Foundation, Inc. Devices and methods for pharmacokinetic-based cell culture system
ATE406436T1 (de) 2001-07-26 2008-09-15 Transparent Inc Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon
US20030064000A1 (en) 2001-09-24 2003-04-03 Wilson Burgess Methods of sterilizing biological mixtures using stabilizer mixtures
WO2003101618A1 (en) 2002-05-31 2003-12-11 Cancer Research Technology Ltd Substrate for holding an array of experimental samples
US20040067585A1 (en) 2002-10-07 2004-04-08 Yu-Chi Wang Cell cultivation surface and method of making the same
US7190449B2 (en) 2002-10-28 2007-03-13 Nanopoint, Inc. Cell tray
EP2233564A3 (en) 2002-10-30 2012-11-21 Hitachi, Ltd. Cell culture sheet comprising a functional substrate with a group of columnar micro-pillars and its manufacturing method
US7799378B2 (en) 2002-11-27 2010-09-21 Japan Science And Technology Agency Process for producing micropillar structure
US7329537B2 (en) 2003-04-17 2008-02-12 Nexcelom Bioscience, Llc Micro-pattern embedded plastic optical film device for cell-based assays
EP1636332A4 (en) 2003-05-06 2007-08-29 Bellbrook Labs Llc THREE DIMENSIONAL CELL CULTURES IN A MICROMASSIFICATION FLUID PROCESSING SYSTEM
EP1626278A3 (en) 2004-08-03 2006-06-21 OnChip Cellomics Consortium Cellomics system
WO2006052223A1 (en) 2004-11-11 2006-05-18 Agency For Science, Technology And Research Cell culture device
US20060228386A1 (en) 2005-02-22 2006-10-12 University Of Tennessee Research Foundation Polymeric microstructures
US20080227656A1 (en) 2005-04-26 2008-09-18 Flemming Besenbacher Biosurface Structure Array
GB2427688A (en) 2005-06-28 2007-01-03 Inogen S A Microwell plate
CA2621658C (en) 2005-09-15 2012-10-23 Sweet Power Inc. Microbial fuel cell with flexible substrate and micro-pillar structure
US20070249044A1 (en) 2006-01-30 2007-10-25 University Of Illinois At Chicago Microstructures in three dimensional gel suspensions for growth of cells
JP4506987B2 (ja) 2006-07-21 2010-07-21 株式会社日立ハイテクノロジーズ エネルギ線硬化型樹脂の転写方法、転写装置及びディスクまたは半導体デバイス
JP5013584B2 (ja) 2006-08-30 2012-08-29 株式会社日立製作所 軟骨細胞の培養方法および軟骨細胞

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