JP2013507922A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013507922A5 JP2013507922A5 JP2012534269A JP2012534269A JP2013507922A5 JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5 JP 2012534269 A JP2012534269 A JP 2012534269A JP 2012534269 A JP2012534269 A JP 2012534269A JP 2013507922 A5 JP2013507922 A5 JP 2013507922A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cell culture
- trough
- micrometers
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004113 cell culture Methods 0.000 claims description 22
- 230000010412 perfusion Effects 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 6
- 239000006143 cell culture medium Substances 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 claims 16
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 230000002262 irrigation Effects 0.000 claims 1
- 238000003973 irrigation Methods 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25075409P | 2009-10-12 | 2009-10-12 | |
| US61/250,754 | 2009-10-12 | ||
| PCT/US2010/052212 WO2011046884A2 (en) | 2009-10-12 | 2010-10-12 | Microfluidic device for cell culture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013507922A JP2013507922A (ja) | 2013-03-07 |
| JP2013507922A5 true JP2013507922A5 (https=) | 2013-05-30 |
Family
ID=43855151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534269A Abandoned JP2013507922A (ja) | 2009-10-12 | 2010-10-12 | 細胞培養用マイクロ流体デバイス |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8481303B2 (https=) |
| EP (1) | EP2488628A2 (https=) |
| JP (1) | JP2013507922A (https=) |
| CN (1) | CN102612554A (https=) |
| WO (1) | WO2011046884A2 (https=) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7534601B2 (en) * | 2002-08-27 | 2009-05-19 | Vanderbilt University | Capillary perfused bioreactors with multiple chambers |
| EP2358860A1 (en) * | 2008-11-21 | 2011-08-24 | Corning Incorporated | Spaced projection substrates and devices for cell culture |
| JP5879267B2 (ja) * | 2009-10-29 | 2016-03-08 | ザ・チャールズ・スターク・ドレイパ・ラボラトリー・インコーポレイテッド | 血液透析用マイクロ流体装置 |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| CN102234614B (zh) * | 2011-05-30 | 2013-02-13 | 中国科学院苏州纳米技术与纳米仿生研究所 | 微流控细胞悬浮培养芯片及其应用 |
| KR101970634B1 (ko) | 2011-06-02 | 2019-04-19 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 생체외 조직 배양 시스템을 위한 방법 및 용도 |
| WO2012174460A1 (en) * | 2011-06-15 | 2012-12-20 | The Charles Stark Draper Laboratory, Inc. | Systems, methods, and devices relating to a biomimetic cellularized nephron unit |
| JP2014516582A (ja) * | 2011-06-15 | 2014-07-17 | ザ チャールズ スターク ドレイパー ラボラトリー インク | 生体模倣環境において細胞を培養するためのデバイスおよび方法 |
| US10640807B2 (en) | 2011-12-29 | 2020-05-05 | S.D. Sight Diagnostics Ltd | Methods and systems for detecting a pathogen in a biological sample |
| WO2014031523A2 (en) * | 2012-08-19 | 2014-02-27 | University Of Rochester | Method for preparing microfluidic device with reduced channel height |
| US20140127733A1 (en) * | 2012-11-01 | 2014-05-08 | Moffit Cancer Center | Ex vivo microfluidic analysis of biologic samples |
| EP2972313B1 (en) | 2013-03-15 | 2018-01-03 | Rinker, Kristina, D. | Ported parallel plate flow chamber and methods for use thereof |
| EP2999988A4 (en) | 2013-05-23 | 2017-01-11 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| EP3024921B1 (en) | 2013-07-22 | 2025-12-10 | The Regents of The University of California | Microfluidics cell culture device |
| WO2015029032A1 (en) | 2013-08-26 | 2015-03-05 | Parasight Ltd. | Digital microscopy systems, methods and computer program products |
| US20150064689A1 (en) * | 2013-08-29 | 2015-03-05 | The Charles Stark Draper Laboratory, Inc. | System and method for analyzing transmissibility of influenza |
| CN103627635B (zh) * | 2013-11-18 | 2015-05-20 | 辽宁中医药大学 | 一种用于细胞迁移和侵袭实验的多功能微流控芯片 |
| US20150247112A1 (en) * | 2014-03-03 | 2015-09-03 | Kiyatec Inc. | 3D Tissue Culture Devices and Systems |
| US9631167B2 (en) * | 2014-03-21 | 2017-04-25 | Iontox, Llc | Dynamic multi organ plate |
| EP3177709B1 (en) | 2014-08-07 | 2022-05-18 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Reversible stencils for fabricating micro-tissues |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| CN104293666B (zh) * | 2014-09-11 | 2016-06-22 | 大连理工大学 | 两种不同单细胞之间相互作用的微流控芯片装置 |
| CN105713835B (zh) * | 2014-12-05 | 2018-11-09 | 中国科学院大连化学物理研究所 | 一种基于微流控芯片的多功能区域细胞三维共培养方法 |
| US10279345B2 (en) | 2014-12-12 | 2019-05-07 | Opko Diagnostics, Llc | Fluidic systems comprising an incubation channel, including fluidic systems formed by molding |
| US10723988B2 (en) | 2015-04-22 | 2020-07-28 | Berkeley Lights, Inc. | Microfluidic cell culture |
| GB201512600D0 (en) * | 2015-07-17 | 2015-08-26 | Koniku Ltd | Cell culture, transport and investigation |
| US10488644B2 (en) | 2015-09-17 | 2019-11-26 | S.D. Sight Diagnostics Ltd. | Methods and apparatus for detecting an entity in a bodily sample |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| GB2560290B (en) | 2015-12-04 | 2022-03-09 | Emulate Inc | Open-Top Microfluidic Device With Structural Anchors |
| US11744708B2 (en) * | 2016-02-16 | 2023-09-05 | Koninklijke Philips N.V. | Surface topographies for altering the physiology of living cells |
| WO2017172638A1 (en) * | 2016-03-29 | 2017-10-05 | Smsbiotech, Inc. | Compositions and methods for using small mobile stem cells |
| CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
| US11414635B2 (en) | 2016-04-18 | 2022-08-16 | Saint Louis University | Integration of three dimensional cell culture scaffolds in microfluidic devices by direct fiber spinning |
| EP3455626B1 (en) | 2016-05-11 | 2025-08-06 | S.D. Sight Diagnostics Ltd. | Performing optical measurements on a sample |
| WO2017195205A1 (en) | 2016-05-11 | 2017-11-16 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
| IL263274B2 (en) | 2016-05-26 | 2023-10-01 | Berkeley Lights Inc | Covalently adapted surfaces, kits and methods for their production and uses |
| CN105838606B (zh) * | 2016-06-08 | 2018-10-02 | 牛海涛 | 一种高通量细胞联合培养芯片 |
| US10243097B2 (en) * | 2016-09-09 | 2019-03-26 | eLux Inc. | Fluidic assembly using tunable suspension flow |
| WO2018080308A2 (en) * | 2016-10-28 | 2018-05-03 | Materiomics B.V. | Surface topographies for stimulating endothelialization |
| US11474103B2 (en) | 2017-02-17 | 2022-10-18 | Koniku Inc. | Systems for detection |
| CA3055767A1 (en) * | 2017-03-31 | 2018-10-04 | Dana-Farber Cancer Institute, Inc. | Methods for evaluating tumor cell spheroids using 3d microfluidic cell culture device |
| EP3606669A1 (en) | 2017-04-03 | 2020-02-12 | The Charles Stark Draper Laboratory, Inc. | Microfluidic system for evaluation of chemotherapeutic and immunotherapeutic drugs |
| CN111788471B (zh) | 2017-11-14 | 2023-12-12 | 思迪赛特诊断有限公司 | 用于光学测量的样品载体 |
| KR101979145B1 (ko) * | 2018-01-30 | 2019-05-15 | 서강대학교산학협력단 | 신경줄기세포 배양용 미세유체칩 및 이의 용도 |
| WO2020081288A1 (en) * | 2018-10-14 | 2020-04-23 | Arizona Board Of Regents On Behalf Of Arizona State University | Microfluidic devices and methods incorporating organized three-dimensional tissue constructs |
| KR102170851B1 (ko) * | 2018-11-13 | 2020-10-27 | 엠비디 주식회사 | 세포 배양 플레이트 |
| US12305153B2 (en) * | 2019-05-13 | 2025-05-20 | Newsouth Innovations Pty Limited | Microfluidic device and method of use for cell culture |
| AU2020370212B2 (en) | 2019-10-22 | 2025-09-25 | S.D. Sight Diagnostics Ltd | Accounting for errors in optical measurements |
| CN114787625B (zh) | 2019-12-12 | 2026-01-13 | 思迪赛特诊断有限公司 | 检测血液样品中的血小板 |
| BR112022011312A2 (pt) | 2019-12-12 | 2022-08-23 | S D Sight Diagnostics Ltd | Análise de um analito disposto dentro de um meio |
| JP7677972B2 (ja) | 2019-12-12 | 2025-05-15 | エス.ディー.サイト ダイアグノスティックス リミテッド | カラー血液スミア画像の人工的な生成 |
| CN111068516B (zh) * | 2020-01-18 | 2023-11-14 | 浙江大学 | 多元强化耦合智能调控防止高粘性灰在催化剂表面沉积的系统及方法 |
| GB202002010D0 (en) * | 2020-02-13 | 2020-04-01 | Univ Of Nottingham Research | Microtopographies and uses thereof |
| US20240034973A1 (en) * | 2020-12-02 | 2024-02-01 | Ushio Denki Kabushiki Kaisha | Culture vessel, and method of using culture vessel |
| EP4281534A4 (en) * | 2021-01-22 | 2024-03-13 | Hewlett-Packard Development Company, L.P. | MICROFLUIDIC DEVICE CHAMBER PILLARS |
| US20240299942A1 (en) * | 2021-06-30 | 2024-09-12 | Hewlett-Packard Development Company, L.P. | Microfluidic device chamber pillars |
| CN114453039B (zh) * | 2022-02-08 | 2025-09-30 | 浙江扬清芯片技术有限公司 | 一种离心式微流控芯片点阵阀结构 |
| US12186748B2 (en) | 2022-06-24 | 2025-01-07 | Hewlett-Packard Development Company, L.P. | Self-priming microfluidic structures |
| CN115742293A (zh) * | 2022-11-01 | 2023-03-07 | 福建星海通信科技有限公司 | 一种基于dlp3d打印的生物应用微流体器件制备方法 |
| CN121446571A (zh) * | 2026-01-05 | 2026-02-03 | 四川迪亚生物科技集团有限公司 | 一种基于乏氧微环境的微流控芯片制备方法及其应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1437404A (en) | 1973-09-24 | 1976-05-26 | Kaye S | Method and means for assaying biological factors demonstrating quantal response |
| DE3275216D1 (en) | 1981-09-18 | 1987-02-26 | Bbc Brown Boveri & Cie | Storage cavern for air under constant pressure with a hydraulic pressure compensation for a gas turbine power plant |
| DE4116727C2 (de) | 1991-05-17 | 1995-09-07 | Uwe Dr Marx | Verfahren und Vorrichtung zur gleichzeitigen Kultivierung unterschiedlicher Säugerzellen |
| DE4132379A1 (de) | 1991-09-28 | 1993-04-08 | Kernforschungsz Karlsruhe | Substrat fuer zellkulturen und kultur von zellen oder zellaggregaten |
| CA2175660C (en) | 1993-11-02 | 2005-07-05 | Charles S. Naiman | Control of cell growth |
| FR2741357B1 (fr) | 1995-11-22 | 1998-01-16 | Corning Inc | Procede de fabrication d'une plaquette de support d'un reseau bidimensionnel de micropuits, notamment pour essais ou cultures biologiques |
| US6391578B2 (en) | 1997-04-09 | 2002-05-21 | 3M Innovative Properties Company | Method and devices for partitioning biological sample liquids into microvolumes |
| CH692583A5 (de) | 1998-03-03 | 2002-08-15 | Weidmann H Ag | Kulturgefäss. |
| GB9805214D0 (en) | 1998-03-11 | 1998-05-06 | Univ Glasgow | Cell adhesion |
| WO1999047922A2 (en) | 1998-03-18 | 1999-09-23 | Massachusetts Institute Of Technology | Vascularized perfused microtissue/micro-organ arrays |
| JP2000231007A (ja) | 1999-02-09 | 2000-08-22 | Ricoh Opt Ind Co Ltd | 凹型微細形状のアレイ状パターン形成方法及びその形成方法を用いて製作される平板型レンズアレイ及び液晶表示素子及び平板型オイルトラップ |
| US7033821B2 (en) | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | Device for monitoring cell motility in real-time |
| US7211209B2 (en) | 2000-11-08 | 2007-05-01 | Surface Logix, Inc. | Method of making device for arraying biomolecules and for monitoring cell motility in real-time |
| US6653124B1 (en) | 2000-11-10 | 2003-11-25 | Cytoplex Biosciences Inc. | Array-based microenvironment for cell culturing, cell monitoring and drug-target validation |
| US7018418B2 (en) | 2001-01-25 | 2006-03-28 | Tecomet, Inc. | Textured surface having undercut micro recesses in a surface |
| US7288405B2 (en) | 2001-04-25 | 2007-10-30 | Cornell Research Foundation, Inc. | Devices and methods for pharmacokinetic-based cell culture system |
| ATE406436T1 (de) | 2001-07-26 | 2008-09-15 | Transparent Inc | Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon |
| US20030064000A1 (en) | 2001-09-24 | 2003-04-03 | Wilson Burgess | Methods of sterilizing biological mixtures using stabilizer mixtures |
| WO2003101618A1 (en) | 2002-05-31 | 2003-12-11 | Cancer Research Technology Ltd | Substrate for holding an array of experimental samples |
| US20040067585A1 (en) | 2002-10-07 | 2004-04-08 | Yu-Chi Wang | Cell cultivation surface and method of making the same |
| US7190449B2 (en) | 2002-10-28 | 2007-03-13 | Nanopoint, Inc. | Cell tray |
| EP2233564A3 (en) | 2002-10-30 | 2012-11-21 | Hitachi, Ltd. | Cell culture sheet comprising a functional substrate with a group of columnar micro-pillars and its manufacturing method |
| US7799378B2 (en) | 2002-11-27 | 2010-09-21 | Japan Science And Technology Agency | Process for producing micropillar structure |
| US7329537B2 (en) | 2003-04-17 | 2008-02-12 | Nexcelom Bioscience, Llc | Micro-pattern embedded plastic optical film device for cell-based assays |
| EP1636332A4 (en) | 2003-05-06 | 2007-08-29 | Bellbrook Labs Llc | THREE DIMENSIONAL CELL CULTURES IN A MICROMASSIFICATION FLUID PROCESSING SYSTEM |
| EP1626278A3 (en) | 2004-08-03 | 2006-06-21 | OnChip Cellomics Consortium | Cellomics system |
| WO2006052223A1 (en) | 2004-11-11 | 2006-05-18 | Agency For Science, Technology And Research | Cell culture device |
| US20060228386A1 (en) | 2005-02-22 | 2006-10-12 | University Of Tennessee Research Foundation | Polymeric microstructures |
| US20080227656A1 (en) | 2005-04-26 | 2008-09-18 | Flemming Besenbacher | Biosurface Structure Array |
| GB2427688A (en) | 2005-06-28 | 2007-01-03 | Inogen S A | Microwell plate |
| CA2621658C (en) | 2005-09-15 | 2012-10-23 | Sweet Power Inc. | Microbial fuel cell with flexible substrate and micro-pillar structure |
| US20070249044A1 (en) | 2006-01-30 | 2007-10-25 | University Of Illinois At Chicago | Microstructures in three dimensional gel suspensions for growth of cells |
| JP4506987B2 (ja) | 2006-07-21 | 2010-07-21 | 株式会社日立ハイテクノロジーズ | エネルギ線硬化型樹脂の転写方法、転写装置及びディスクまたは半導体デバイス |
| JP5013584B2 (ja) | 2006-08-30 | 2012-08-29 | 株式会社日立製作所 | 軟骨細胞の培養方法および軟骨細胞 |
-
2010
- 2010-03-03 US US12/716,680 patent/US8481303B2/en not_active Expired - Fee Related
- 2010-10-12 EP EP10766202A patent/EP2488628A2/en not_active Withdrawn
- 2010-10-12 JP JP2012534269A patent/JP2013507922A/ja not_active Abandoned
- 2010-10-12 WO PCT/US2010/052212 patent/WO2011046884A2/en not_active Ceased
- 2010-10-12 CN CN2010800468967A patent/CN102612554A/zh active Pending
-
2013
- 2013-06-06 US US13/911,490 patent/US8679843B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013507922A5 (https=) | ||
| WO2011046884A3 (en) | Microfluidic device for cell culture | |
| WO2010056750A3 (en) | Battery system with heat exchanger | |
| JP2013526269A5 (https=) | ||
| WO2011129545A3 (ko) | 신규한 구조의 전지팩 케이스 | |
| WO2011141512A3 (en) | Apparatus and methods for cell culture | |
| CN202745020U (zh) | 一种用于洄游性鱼类过坝保护的透水式鱼道 | |
| WO2012115351A3 (ko) | 냉각 효율성이 향상된 냉각부재와 이를 포함하는 전지모듈 | |
| WO2010014902A8 (en) | Horizontal plate microbial support media | |
| TR201911112T4 (tr) | Geliştirilmiş akışa sahip ısı değiştirici. | |
| JP2013522461A5 (https=) | ||
| ATE486376T1 (de) | Generator von elektrischer energie basiert auf den thermoelektrischen effekt | |
| CN201796995U (zh) | 用于燃料电池的极板及其燃料电池 | |
| CN104885271B (zh) | 便于除水的反应物流动通道构造 | |
| JP2013529361A5 (https=) | ||
| CA2925051C (en) | Reactant flow channels for electrolyzer applications | |
| CN102983343A (zh) | 带有亲水导流针的质子交换膜燃料电池流道 | |
| TW201130190A (en) | Bipolar plate structure of fuel cell | |
| CN202217645U (zh) | 一种多晶硅湿刻机的抽风盖板 | |
| CN206361863U (zh) | 一种可以消除布水阴影区的水蓄冷布水器 | |
| CN104058502A (zh) | 一种均压紊流型布水器 | |
| WO2011149243A3 (ko) | 성형용 금형 및 이를 갖는 성형 시스템 | |
| CN110970648A (zh) | 一种液流电池电堆 | |
| CN202272763U (zh) | 小分子水发生器的导流盘 | |
| CN202907652U (zh) | 滩涂贝类围塘养殖微孔底增氧装置 |