JP2013506837A5 - - Google Patents
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- JP2013506837A5 JP2013506837A5 JP2012532147A JP2012532147A JP2013506837A5 JP 2013506837 A5 JP2013506837 A5 JP 2013506837A5 JP 2012532147 A JP2012532147 A JP 2012532147A JP 2012532147 A JP2012532147 A JP 2012532147A JP 2013506837 A5 JP2013506837 A5 JP 2013506837A5
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- Prior art keywords
- test sample
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- target antigens
- target
- antigens
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- 239000000427 antigen Substances 0.000 claims description 40
- 102000038129 antigens Human genes 0.000 claims description 38
- 108091007172 antigens Proteins 0.000 claims description 38
- 206010004661 Biliary cirrhosis primary Diseases 0.000 claims description 16
- 201000002728 primary biliary cirrhosis Diseases 0.000 claims description 16
- 102000003852 Autoantibodies Human genes 0.000 claims description 7
- 108090000206 Autoantibodies Proteins 0.000 claims description 7
- 210000001124 Body Fluids Anatomy 0.000 claims description 5
- 239000010839 body fluid Substances 0.000 claims description 5
- 210000004369 Blood Anatomy 0.000 claims description 4
- 210000002381 Plasma Anatomy 0.000 claims description 4
- 210000002966 Serum Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 210000004027 cells Anatomy 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 210000001519 tissues Anatomy 0.000 claims description 4
- 101700038001 GLK1 Proteins 0.000 claims 4
- 101700042033 HK1 Proteins 0.000 claims 4
- 102100008927 HK1 Human genes 0.000 claims 4
- 101700067830 HXK1 Proteins 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- 102000004965 antibodies Human genes 0.000 description 4
- 108090001123 antibodies Proteins 0.000 description 4
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24876809P | 2009-10-05 | 2009-10-05 | |
US61/248,768 | 2009-10-05 | ||
PCT/US2010/051475 WO2011044125A1 (en) | 2009-10-05 | 2010-10-05 | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015041977A Division JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変(pbc)を診断するための方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2013506837A JP2013506837A (ja) | 2013-02-28 |
JP2013506837A5 true JP2013506837A5 (US07794700-20100914-C00194.png) | 2013-10-17 |
JP5710623B2 JP5710623B2 (ja) | 2015-04-30 |
Family
ID=43857083
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012532147A Active JP5710623B2 (ja) | 2009-10-05 | 2010-10-05 | 自己抗原を使用する原発性胆汁性肝硬変(pbc)を診断するための方法 |
JP2015041977A Active JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変(pbc)を診断するための方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015041977A Active JP6012794B2 (ja) | 2009-10-05 | 2015-03-04 | 自己抗原を使用する原発性胆汁性肝硬変(pbc)を診断するための方法 |
Country Status (7)
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2965189C (en) * | 2009-10-05 | 2020-06-30 | Ambergen, Inc. | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
CN102627695B (zh) * | 2012-03-23 | 2014-10-22 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
CN104292323B (zh) * | 2012-03-23 | 2017-04-05 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
CN104292322A (zh) * | 2012-03-23 | 2015-01-21 | 中国医学科学院北京协和医院 | 原发性胆汁性肝硬化特异性自身抗原及其应用 |
US20220196662A1 (en) * | 2019-03-15 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | Autoantibodies as biomarker of paraneoplastic encephalitis associated with testicular cancer |
WO2022150536A1 (en) * | 2021-01-08 | 2022-07-14 | Inova Diagnostics, Inc. | Compositions and methods for diagnosing primary biliary cirrhosis |
CN113009148A (zh) * | 2021-02-10 | 2021-06-22 | 中国医学科学院北京协和医院 | 用于诊断抗sp100抗体阳性与阴性pbc患者的糖链标志物及其用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
CA1341231C (en) | 1986-12-16 | 2001-05-15 | Ross Leon Coppel | Primary biliary cirrhosis autoantigen |
JPH03291568A (ja) * | 1990-04-09 | 1991-12-20 | Igaku Seibutsugaku Kenkyusho:Kk | 抗ミトコンドリアm↓2抗体の検出用試薬及び測定法 |
JP3472048B2 (ja) * | 1995-10-09 | 2003-12-02 | 鐘淵化学工業株式会社 | 自己免疫疾患の診断薬 |
CA2256684A1 (en) * | 1996-06-24 | 1997-12-31 | Patrick Leung | Recombinant fusion protein comprising pdc-e2, bcoadc-e2, and ogdc-e2 and uses thereof |
JPH1138008A (ja) * | 1997-07-16 | 1999-02-12 | Sumitomo Electric Ind Ltd | 自己抗体の検出方法および検出試薬 |
WO2002008383A2 (en) * | 2000-07-24 | 2002-01-31 | The General Hospital Corporation | Sp110, a polypeptide component of the nuclear body |
AU2002254431A1 (en) * | 2001-03-27 | 2002-10-08 | M. Eric Gershwin | Antibodies against autoantigens of primary biliary cirrhosis and methods of making and using them |
NZ548532A (en) * | 2004-01-21 | 2009-09-25 | Gilead Sciences Inc | Use of adefovir or tenofovir for inhibiting MMTV-like viruses involved in breast cancer and primary biliary cirrhosis |
JP2006071409A (ja) * | 2004-09-01 | 2006-03-16 | Kansai Tlo Kk | シェーグレン症候群診断キット |
WO2007043103A1 (ja) * | 2005-09-30 | 2007-04-19 | Kansai Technology Licensing Organization Co., Ltd. | シェーグレン症候群診断法及び診断キット |
JP2007245505A (ja) | 2006-03-15 | 2007-09-27 | Fujifilm Corp | 平版印刷版原版、平版印刷版およびその作製方法 |
US20090047689A1 (en) * | 2007-06-20 | 2009-02-19 | John Kolman | Autoantigen biomarkers for early diagnosis of lung adenocarcinoma |
JP5471724B2 (ja) | 2009-09-30 | 2014-04-16 | 大日本印刷株式会社 | 化粧シート |
CA2965189C (en) * | 2009-10-05 | 2020-06-30 | Ambergen, Inc. | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
JP2012206482A (ja) | 2011-03-30 | 2012-10-25 | Daikyonishikawa Corp | 樹脂成形品の組付け構造 |
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2010
- 2010-10-05 CA CA2965189A patent/CA2965189C/en active Active
- 2010-10-05 ES ES15194007.9T patent/ES2681839T3/es active Active
- 2010-10-05 EP EP15194007.9A patent/EP3012631B1/en active Active
- 2010-10-05 US US13/500,411 patent/US8852956B2/en active Active
- 2010-10-05 EP EP10822527.7A patent/EP2486407B1/en active Active
- 2010-10-05 WO PCT/US2010/051475 patent/WO2011044125A1/en active Application Filing
- 2010-10-05 ES ES10822527.7T patent/ES2566762T3/es active Active
- 2010-10-05 AU AU2010303628A patent/AU2010303628B2/en active Active
- 2010-10-05 JP JP2012532147A patent/JP5710623B2/ja active Active
- 2010-10-05 CA CA2776688A patent/CA2776688C/en active Active
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2014
- 2014-06-27 US US14/318,498 patent/US20150057170A1/en not_active Abandoned
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2015
- 2015-03-04 JP JP2015041977A patent/JP6012794B2/ja active Active
- 2015-10-07 AU AU2015238816A patent/AU2015238816B2/en active Active
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2017
- 2017-03-24 US US15/469,350 patent/US11885802B2/en active Active
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2023
- 2023-11-28 US US18/522,114 patent/US20240159749A1/en active Pending