JP2013505255A5 - - Google Patents
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- Publication number
- JP2013505255A5 JP2013505255A5 JP2012529909A JP2012529909A JP2013505255A5 JP 2013505255 A5 JP2013505255 A5 JP 2013505255A5 JP 2012529909 A JP2012529909 A JP 2012529909A JP 2012529909 A JP2012529909 A JP 2012529909A JP 2013505255 A5 JP2013505255 A5 JP 2013505255A5
- Authority
- JP
- Japan
- Prior art keywords
- digestive enzyme
- multiparticulate
- coating
- enzyme composition
- lipase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000038379 digestive enzymes Human genes 0.000 claims 42
- 108091007734 digestive enzymes Proteins 0.000 claims 42
- 239000011324 bead Substances 0.000 claims 24
- 239000000203 mixture Substances 0.000 claims 24
- 108091005804 Peptidases Proteins 0.000 claims 15
- 239000004365 Protease Substances 0.000 claims 15
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 15
- 239000011248 coating agent Substances 0.000 claims 13
- 238000000576 coating method Methods 0.000 claims 13
- 239000002702 enteric coating Substances 0.000 claims 10
- 238000009505 enteric coating Methods 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 9
- 235000019626 lipase activity Nutrition 0.000 claims 9
- 102000004882 Lipase Human genes 0.000 claims 7
- 108090001060 Lipase Proteins 0.000 claims 7
- 239000004367 Lipase Substances 0.000 claims 6
- 235000019421 lipase Nutrition 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 4
- 208000035467 Pancreatic insufficiency Diseases 0.000 claims 2
- 206010033645 Pancreatitis Diseases 0.000 claims 2
- 235000012054 meals Nutrition 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 206010000087 Abdominal pain upper Diseases 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24346709P | 2009-09-17 | 2009-09-17 | |
| US61/243,467 | 2009-09-17 | ||
| PCT/US2010/049203 WO2011035079A1 (en) | 2009-09-17 | 2010-09-17 | Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013505255A JP2013505255A (ja) | 2013-02-14 |
| JP2013505255A5 true JP2013505255A5 (cg-RX-API-DMAC7.html) | 2013-11-07 |
| JP5877399B2 JP5877399B2 (ja) | 2016-03-08 |
Family
ID=43730817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012529909A Expired - Fee Related JP5877399B2 (ja) | 2009-09-17 | 2010-09-17 | 膵炎及び膵不全を治療するための膵酵素組成物及び方法 |
Country Status (23)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
| CN101686943B (zh) | 2007-02-20 | 2014-03-26 | 阿普塔利斯制药有限公司 | 稳定的消化酶组合物 |
| US10087493B2 (en) | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
| EP2818160B1 (en) * | 2010-10-01 | 2017-11-08 | Aptalis Pharma Limited | Enteric coated, low-strength pancrelipase formulations |
| KR101953413B1 (ko) | 2011-08-08 | 2019-02-28 | 앨러간 파마슈티컬스 인터내셔널 리미티드 | 소화효소들을 함유하는 고형 조성물들의 용해 시험 방법 |
| ES2784227T3 (es) | 2013-08-09 | 2020-09-23 | Allergan Pharmaceuticals Int Ltd | Composición de enzimas digestivos adecuada para la administración entérica |
| WO2015193730A1 (en) | 2014-06-19 | 2015-12-23 | Aptalis Pharma Ltd. | Methods for removing viral contaminants from pancreatic extracts |
| FR3079146B1 (fr) * | 2018-03-23 | 2020-04-17 | Karim Ioualalen | Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive. |
| WO2021202363A1 (en) * | 2020-03-30 | 2021-10-07 | Wall Jai | Combined animal-derived and synthetically produced pancreatic enzyme replacement therapy |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509866A (en) | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
| US4447412A (en) * | 1983-02-01 | 1984-05-08 | Bilton Gerald L | Enzyme-containing digestive aid compostions |
| US5578304A (en) | 1992-06-22 | 1996-11-26 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5260074A (en) | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5460812A (en) | 1992-06-22 | 1995-10-24 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
| US5302400A (en) | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
| DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
| EP0879048B2 (en) | 1996-02-09 | 2009-07-29 | Quadrant Drug Delivery Limited | Method for making tablets using trehalose |
| US5750104A (en) | 1996-05-29 | 1998-05-12 | Digestive Care Inc. | High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith |
| US20010046493A1 (en) | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
| CN1156308C (zh) * | 2002-04-19 | 2004-07-07 | 北京世诺医药科技有限公司 | 多酶组合胶囊 |
| US20040121010A1 (en) * | 2002-10-25 | 2004-06-24 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| EP1596838A2 (en) | 2003-02-11 | 2005-11-23 | Torrent Pharmaceuticals Ltd | Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent |
| AU2004285558A1 (en) | 2003-10-29 | 2005-05-12 | Altus Pharmaceuticals Inc. | Non-pancreatic proteases for controlling plasma cholecystokinin (CCK) concentration and for treating pain |
| US7387793B2 (en) | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
| US7470435B2 (en) | 2003-11-17 | 2008-12-30 | Andrx Pharmaceuticals, Llc | Extended release venlafaxine formulation |
| RU2381813C2 (ru) | 2004-03-22 | 2010-02-20 | Зольвай Фармасьютиклз Гмбх | Пероральные фармацевтические композиции на основе продуктов, содержащих липазы, прежде всего панкреатин, и пав |
| WO2005115445A1 (en) * | 2004-05-24 | 2005-12-08 | Novozymes A/S | Enzymes for pharmaceutical use |
| DE602005022471D1 (de) * | 2004-10-14 | 2010-09-02 | Altus Pharmaceuticals Inc | Zusammensetzungen enthaltend lipase, protease und amylase zur behandlung von pankreasinsuffizienz |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| MX2007015472A (es) * | 2005-06-24 | 2008-04-17 | Novozymes As | Lipasas para uso farmaceutico. |
| US20070025977A1 (en) | 2005-07-21 | 2007-02-01 | Mulberg Andrew E | Method of treating steatorrhea in infants |
| CA2616943C (en) | 2005-07-29 | 2016-04-12 | Solvay Pharmaceuticals Gmbh | Processes for the manufacture of sterilized pancreatin powder |
| US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
| US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
| WO2007053619A2 (en) * | 2005-11-01 | 2007-05-10 | Bio-Cat, Inc. | A composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrous as well as people suffering from pancreatic lipase insufficiency |
| MX2008015031A (es) * | 2006-05-26 | 2008-12-05 | Nestec Sa | Metodos de uso y composiciones nutritivas de extracto de touchi. |
| US20080199448A1 (en) * | 2007-02-16 | 2008-08-21 | Ross Mairi R | Enzyme composition for improving food digestion |
| CN101686943B (zh) | 2007-02-20 | 2014-03-26 | 阿普塔利斯制药有限公司 | 稳定的消化酶组合物 |
| US20090117180A1 (en) * | 2007-02-20 | 2009-05-07 | Giovanni Ortenzi | Stable digestive enzyme compositions |
| EP2328566A1 (en) | 2008-09-30 | 2011-06-08 | DSM IP Assets B.V. | Enzyme composition and application thereof in the treatment of pancreatic insufficiency |
-
2009
- 2009-09-28 US US12/568,064 patent/US8784884B2/en active Active
-
2010
- 2010-09-16 TW TW105126319A patent/TW201639545A/zh unknown
- 2010-09-16 TW TW099131496A patent/TWI572372B/zh not_active IP Right Cessation
- 2010-09-17 JP JP2012529909A patent/JP5877399B2/ja not_active Expired - Fee Related
- 2010-09-17 BR BR112012005837A patent/BR112012005837A8/pt not_active Application Discontinuation
- 2010-09-17 AR ARP100103408A patent/AR078291A1/es not_active Application Discontinuation
- 2010-09-17 NZ NZ599143A patent/NZ599143A/en not_active IP Right Cessation
- 2010-09-17 WO PCT/US2010/049203 patent/WO2011035079A1/en not_active Ceased
- 2010-09-17 KR KR1020127009516A patent/KR101771752B1/ko not_active Expired - Fee Related
- 2010-09-17 MX MX2012003214A patent/MX2012003214A/es active IP Right Grant
- 2010-09-17 CA CA2774269A patent/CA2774269C/en not_active Expired - Fee Related
- 2010-09-17 MY MYPI2012001215A patent/MY161843A/en unknown
- 2010-09-17 AU AU2010295494A patent/AU2010295494B2/en not_active Ceased
- 2010-09-17 CN CN201510490337.XA patent/CN105214073A/zh active Pending
- 2010-09-17 UY UY0001032896A patent/UY32896A/es not_active Application Discontinuation
- 2010-09-17 RU RU2012113253/15A patent/RU2570376C2/ru active
- 2010-09-17 ES ES10817867.4T patent/ES2690661T3/es active Active
- 2010-09-17 EP EP10817867.4A patent/EP2477645B1/en not_active Revoked
- 2010-09-17 CN CN201080041366.3A patent/CN102630164B/zh not_active Expired - Fee Related
- 2010-09-18 SA SA110310695A patent/SA110310695B1/ar unknown
-
2012
- 2012-03-15 CL CL2012000658A patent/CL2012000658A1/es unknown
- 2012-03-15 IL IL218656A patent/IL218656A/en active IP Right Grant
- 2012-03-26 CO CO12050658A patent/CO6531419A2/es unknown
- 2012-04-16 ZA ZA2012/02761A patent/ZA201202761B/en unknown
-
2014
- 2014-06-05 US US14/296,832 patent/US20160051472A9/en not_active Abandoned
-
2016
- 2016-05-26 IL IL245875A patent/IL245875A0/en unknown
- 2016-06-17 HK HK16107000.5A patent/HK1218886A1/zh unknown
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