JP2013503888A - 癌を治療するための化合物および組成物 - Google Patents
癌を治療するための化合物および組成物 Download PDFInfo
- Publication number
- JP2013503888A JP2013503888A JP2012528029A JP2012528029A JP2013503888A JP 2013503888 A JP2013503888 A JP 2013503888A JP 2012528029 A JP2012528029 A JP 2012528029A JP 2012528029 A JP2012528029 A JP 2012528029A JP 2013503888 A JP2013503888 A JP 2013503888A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- cell
- cancer
- independently selected
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27575409P | 2009-09-02 | 2009-09-02 | |
US61/275,754 | 2009-09-02 | ||
PCT/US2010/047615 WO2011028860A2 (en) | 2009-09-02 | 2010-09-02 | Compounds and compositions for treating cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2013503888A true JP2013503888A (ja) | 2013-02-04 |
Family
ID=43625764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012528029A Pending JP2013503888A (ja) | 2009-09-02 | 2010-09-02 | 癌を治療するための化合物および組成物 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2473506A4 (zh) |
JP (1) | JP2013503888A (zh) |
KR (1) | KR20120104165A (zh) |
CN (1) | CN102625805A (zh) |
AU (1) | AU2010289493A1 (zh) |
BR (1) | BR112012004701A2 (zh) |
CA (1) | CA2772614A1 (zh) |
IN (1) | IN2012DN01878A (zh) |
WO (1) | WO2011028860A2 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020535125A (ja) * | 2017-09-18 | 2020-12-03 | インスティテュート デ メディシナ モレキュラー ジョアオ ロボ アントゥネスInstituto de Medicina Molecular Joao Lobo Antunes | Trpv2アンタゴニスト |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101629642B1 (ko) | 2014-06-25 | 2016-06-13 | 서울대학교산학협력단 | 피퍼롱구민을 유효성분으로 함유하는 지방간 예방용 식품 조성물, 지방간 치료용 약학 조성물, 지방간 치료용 동물 의약품 및 사료 조성물 |
KR20200081633A (ko) | 2018-12-27 | 2020-07-08 | 주식회사 티에스디라이프사이언스 | 피퍼롱구민을 함유하는 담도폐쇄증 치료 또는 예방용 의약 조성물 |
CN110002987B (zh) * | 2019-03-22 | 2020-09-15 | 南通大学 | 苯基亚烯丙基环己烯酮衍生物及制备方法和用途 |
CN117229205A (zh) * | 2023-09-14 | 2023-12-15 | 中国医学科学院基础医学研究所 | 苯基丙烯酰胺类rhbdd1抑制剂制备方法及制药用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2478901A3 (en) | 2007-02-14 | 2012-11-14 | Mars Incorporated | Neurogenic compounds |
EP2135078B1 (en) * | 2007-03-09 | 2013-08-21 | DiscoveRx Corporation | Methods for identifying agents and their use for the prevention or stabilization of fibrosis |
CN102146054A (zh) * | 2010-02-10 | 2011-08-10 | 新昌县来益科技开发有限公司 | 荜茇酰胺衍生物及其药物组合物和在制备抑制肿瘤生长的药物中的用途 |
-
2010
- 2010-09-02 KR KR1020127007113A patent/KR20120104165A/ko not_active Application Discontinuation
- 2010-09-02 JP JP2012528029A patent/JP2013503888A/ja active Pending
- 2010-09-02 CA CA2772614A patent/CA2772614A1/en not_active Abandoned
- 2010-09-02 AU AU2010289493A patent/AU2010289493A1/en not_active Abandoned
- 2010-09-02 WO PCT/US2010/047615 patent/WO2011028860A2/en active Application Filing
- 2010-09-02 EP EP10814469A patent/EP2473506A4/en not_active Withdrawn
- 2010-09-02 CN CN2010800418987A patent/CN102625805A/zh active Pending
- 2010-09-02 BR BR112012004701A patent/BR112012004701A2/pt not_active IP Right Cessation
- 2010-09-02 IN IN1878DEN2012 patent/IN2012DN01878A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020535125A (ja) * | 2017-09-18 | 2020-12-03 | インスティテュート デ メディシナ モレキュラー ジョアオ ロボ アントゥネスInstituto de Medicina Molecular Joao Lobo Antunes | Trpv2アンタゴニスト |
JP7255785B2 (ja) | 2017-09-18 | 2023-04-11 | インスティテュート デ メディシナ モレキュラー ジョアオ ロボ アントゥネス | Trpv2アンタゴニスト |
Also Published As
Publication number | Publication date |
---|---|
EP2473506A4 (en) | 2013-03-06 |
IN2012DN01878A (zh) | 2015-08-21 |
AU2010289493A1 (en) | 2012-04-19 |
WO2011028860A2 (en) | 2011-03-10 |
CN102625805A (zh) | 2012-08-01 |
KR20120104165A (ko) | 2012-09-20 |
BR112012004701A2 (pt) | 2018-06-12 |
CA2772614A1 (en) | 2011-03-10 |
WO2011028860A3 (en) | 2011-07-21 |
EP2473506A2 (en) | 2012-07-11 |
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