JP2013503603A5 - - Google Patents
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- Publication number
- JP2013503603A5 JP2013503603A5 JP2012512108A JP2012512108A JP2013503603A5 JP 2013503603 A5 JP2013503603 A5 JP 2013503603A5 JP 2012512108 A JP2012512108 A JP 2012512108A JP 2012512108 A JP2012512108 A JP 2012512108A JP 2013503603 A5 JP2013503603 A5 JP 2013503603A5
- Authority
- JP
- Japan
- Prior art keywords
- differentiation
- cells
- retinoic acid
- undifferentiated
- control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 9
- 230000004069 differentiation Effects 0.000 claims 8
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 6
- 229930002330 retinoic acid Natural products 0.000 claims 6
- 229960001727 tretinoin Drugs 0.000 claims 6
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 4
- 238000012258 culturing Methods 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 2
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000012423 maintenance Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23929709P | 2009-09-02 | 2009-09-02 | |
| US61/239,297 | 2009-09-02 | ||
| PCT/JP2010/065453 WO2011027908A1 (en) | 2009-09-02 | 2010-09-02 | Method of selecting safe pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013503603A JP2013503603A (ja) | 2013-02-04 |
| JP2013503603A5 true JP2013503603A5 (enExample) | 2013-10-17 |
| JP5682043B2 JP5682043B2 (ja) | 2015-03-11 |
Family
ID=43649441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012512108A Expired - Fee Related JP5682043B2 (ja) | 2009-09-02 | 2010-09-02 | 安全な多能性幹細胞の選択方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8871504B2 (enExample) |
| JP (1) | JP5682043B2 (enExample) |
| WO (1) | WO2011027908A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5936134B2 (ja) * | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
| ES2884838T3 (es) | 2015-04-06 | 2021-12-13 | Univ Leland Stanford Junior | ARN guía químicamente modificados para la regulación génica mediada por CRISPR/CAS |
| WO2018049168A1 (en) | 2016-09-09 | 2018-03-15 | The Board Of Trustees Of The Leland Stanford Junior University | High-throughput precision genome editing |
| EP3643780A4 (en) * | 2017-06-19 | 2021-04-07 | Foundation for Biomedical Research and Innovation at Kobe | METHOD FOR PREDICTING THE DIFFERENTIATION CAPACITY OF PLURIPOTENT STEM CELLS, AND ASSOCIATED REAGENT |
| CN108103027B (zh) * | 2018-02-02 | 2021-12-24 | 中国医学科学院血液病医院（血液学研究所） | 高效率血细胞重编程同时实现基因编辑的方法 |
| US11884915B2 (en) | 2021-09-10 | 2024-01-30 | Agilent Technologies, Inc. | Guide RNAs with chemical modification for prime editing |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2438159B1 (en) | 2009-05-29 | 2018-10-03 | Kyoto University | Method for selecting clone of induced pluripotent stem cells |
| JP5936134B2 (ja) * | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
-
2010
- 2010-09-02 WO PCT/JP2010/065453 patent/WO2011027908A1/en not_active Ceased
- 2010-09-02 US US13/393,103 patent/US8871504B2/en not_active Expired - Fee Related
- 2010-09-02 JP JP2012512108A patent/JP5682043B2/ja not_active Expired - Fee Related
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