JP5682043B2 - 安全な多能性幹細胞の選択方法 - Google Patents

安全な多能性幹細胞の選択方法 Download PDF

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Publication number
JP5682043B2
JP5682043B2 JP2012512108A JP2012512108A JP5682043B2 JP 5682043 B2 JP5682043 B2 JP 5682043B2 JP 2012512108 A JP2012512108 A JP 2012512108A JP 2012512108 A JP2012512108 A JP 2012512108A JP 5682043 B2 JP5682043 B2 JP 5682043B2
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cells
cell
differentiation
pluripotent stem
undifferentiated
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Japanese (ja)
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JP2013503603A5 (enExample
JP2013503603A (ja
Inventor
伸弥 山中
伸弥 山中
茉里 大貫
茉里 大貫
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Kyoto University NUC
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Kyoto University NUC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2012512108A 2009-09-02 2010-09-02 安全な多能性幹細胞の選択方法 Expired - Fee Related JP5682043B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23929709P 2009-09-02 2009-09-02
US61/239,297 2009-09-02
PCT/JP2010/065453 WO2011027908A1 (en) 2009-09-02 2010-09-02 Method of selecting safe pluripotent stem cells

Publications (3)

Publication Number Publication Date
JP2013503603A JP2013503603A (ja) 2013-02-04
JP2013503603A5 JP2013503603A5 (enExample) 2013-10-17
JP5682043B2 true JP5682043B2 (ja) 2015-03-11

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ID=43649441

Family Applications (1)

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JP2012512108A Expired - Fee Related JP5682043B2 (ja) 2009-09-02 2010-09-02 安全な多能性幹細胞の選択方法

Country Status (3)

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US (1) US8871504B2 (enExample)
JP (1) JP5682043B2 (enExample)
WO (1) WO2011027908A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5936134B2 (ja) * 2010-06-15 2016-06-15 国立大学法人京都大学 ヒト人工多能性幹細胞の選択方法
ES2884838T3 (es) 2015-04-06 2021-12-13 Univ Leland Stanford Junior ARN guía químicamente modificados para la regulación génica mediada por CRISPR/CAS
WO2018049168A1 (en) 2016-09-09 2018-03-15 The Board Of Trustees Of The Leland Stanford Junior University High-throughput precision genome editing
EP3643780A4 (en) * 2017-06-19 2021-04-07 Foundation for Biomedical Research and Innovation at Kobe METHOD FOR PREDICTING THE DIFFERENTIATION CAPACITY OF PLURIPOTENT STEM CELLS, AND ASSOCIATED REAGENT
CN108103027B (zh) * 2018-02-02 2021-12-24 中国医学科学院血液病医院（血液学研究所） 高效率血细胞重编程同时实现基因编辑的方法
US11884915B2 (en) 2021-09-10 2024-01-30 Agilent Technologies, Inc. Guide RNAs with chemical modification for prime editing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2438159B1 (en) 2009-05-29 2018-10-03 Kyoto University Method for selecting clone of induced pluripotent stem cells
JP5936134B2 (ja) * 2010-06-15 2016-06-15 国立大学法人京都大学 ヒト人工多能性幹細胞の選択方法

Also Published As

Publication number Publication date
US20120171717A1 (en) 2012-07-05
US8871504B2 (en) 2014-10-28
WO2011027908A1 (en) 2011-03-10
JP2013503603A (ja) 2013-02-04

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