JP2013503178A - タンパク質キナーゼ調節物質としての縮合キノリン - Google Patents
タンパク質キナーゼ調節物質としての縮合キノリン Download PDFInfo
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Classifications
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
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Landscapes
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- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23722709P | 2009-08-26 | 2009-08-26 | |
| US61/237,227 | 2009-08-26 | ||
| US28931709P | 2009-12-22 | 2009-12-22 | |
| US61/289,317 | 2009-12-22 | ||
| PCT/US2010/046760 WO2011025859A1 (en) | 2009-08-26 | 2010-08-26 | Condensed quinolines as protein kinase modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2013503178A true JP2013503178A (ja) | 2013-01-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012526972A Pending JP2013503178A (ja) | 2009-08-26 | 2010-08-26 | タンパク質キナーゼ調節物質としての縮合キノリン |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20110065698A1 (OSRAM) |
| EP (1) | EP2470544A1 (OSRAM) |
| JP (1) | JP2013503178A (OSRAM) |
| KR (1) | KR20120059571A (OSRAM) |
| CN (1) | CN102596969A (OSRAM) |
| AU (1) | AU2010286691A1 (OSRAM) |
| BR (1) | BR112012004304A2 (OSRAM) |
| CA (1) | CA2771890A1 (OSRAM) |
| IL (1) | IL218280A0 (OSRAM) |
| IN (1) | IN2012DN02596A (OSRAM) |
| MX (1) | MX2012002426A (OSRAM) |
| SG (1) | SG178552A1 (OSRAM) |
| WO (1) | WO2011025859A1 (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6437452B2 (ja) | 2013-01-14 | 2018-12-12 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｐｉｍキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物 |
| ME03780B (me) | 2013-01-15 | 2021-04-20 | Incyte Holdings Corp | Jedinjenja tiazolkarboksamida i piridinkarboksamida korisna kao inhibitori pim kinaze |
| EA201690458A1 (ru) | 2013-08-23 | 2016-07-29 | Инсайт Корпорейшн | Фуро- и тиенопиридинкарбоксамиды, используемые в качестве ингибиторов pim-киназы |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| WO2016196244A1 (en) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Pyridineamine compounds useful as pim kinase inhibitors |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| WO2019007795A1 (en) * | 2017-07-03 | 2019-01-10 | Bayer Cropscience Aktiengesellschaft | SUBSTITUTED ISOTHIAZOLOPYRIDONES, PROCESSES FOR PREPARING THEM AND THEIR USE AS HERBICIDES AND / OR PLANT GROWTH REGULATORS |
| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| US11071727B2 (en) | 2018-01-26 | 2021-07-27 | Northwestern University | Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors |
| CN117120447A (zh) * | 2021-03-18 | 2023-11-24 | 薛定谔公司 | 环状化合物和其使用方法 |
| WO2023126951A1 (en) * | 2022-01-03 | 2023-07-06 | Yeda Research And Development Co. Ltd. | Inhibitors of autophagy-related protein-protein interactions |
| GB202213163D0 (en) * | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Novel compounds, compositions and therapeutic uses thereof |
| GB202213166D0 (en) * | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Novel compounds, compositions and therapeutic uses thereof |
Family Cites Families (13)
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|---|---|---|---|---|
| US5559235A (en) | 1991-10-29 | 1996-09-24 | Glaxo Wellcome Inc. | Water soluble camptothecin derivatives |
| US5342947A (en) | 1992-10-09 | 1994-08-30 | Glaxo Inc. | Preparation of water soluble camptothecin derivatives |
| US5681835A (en) | 1994-04-25 | 1997-10-28 | Glaxo Wellcome Inc. | Non-steroidal ligands for the estrogen receptor |
| US5491237A (en) | 1994-05-03 | 1996-02-13 | Glaxo Wellcome Inc. | Intermediates in pharmaceutical camptothecin preparation |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| GB9716557D0 (en) | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
| WO2001021598A1 (en) | 1999-09-23 | 2001-03-29 | Astrazeneca Ab | Therapeutic quinazoline compounds |
| TW200526626A (en) | 2003-09-13 | 2005-08-16 | Astrazeneca Ab | Chemical compounds |
| WO2006089100A1 (en) | 2005-02-17 | 2006-08-24 | Amr Technology, Inc. | Benzoxazole carboxamides for treating cinv and ibs-d |
| BRPI0719123A2 (pt) * | 2006-09-01 | 2013-12-17 | Cylene Pharmaceuticals Inc | Moduladores de serina-treonina proteína cinase e parp |
| CA2716755A1 (en) * | 2008-02-29 | 2009-09-03 | Peter C. Chua | Protein kinase modulators |
| KR20110095857A (ko) * | 2008-09-10 | 2011-08-25 | 칼립시스, 인코포레이티드 | 질환의 치료를 위한 히스타민 수용체의 헤테로시클릭 억제제 |
| TW201204727A (en) * | 2010-03-10 | 2012-02-01 | Kalypsys Inc | Heterocyclic inhibitors of histamine receptors for the treatment of disease |
-
2010
- 2010-08-26 CN CN2010800474008A patent/CN102596969A/zh active Pending
- 2010-08-26 JP JP2012526972A patent/JP2013503178A/ja active Pending
- 2010-08-26 MX MX2012002426A patent/MX2012002426A/es not_active Application Discontinuation
- 2010-08-26 SG SG2012012845A patent/SG178552A1/en unknown
- 2010-08-26 CA CA2771890A patent/CA2771890A1/en not_active Abandoned
- 2010-08-26 IN IN2596DEN2012 patent/IN2012DN02596A/en unknown
- 2010-08-26 BR BR112012004304A patent/BR112012004304A2/pt not_active Application Discontinuation
- 2010-08-26 US US12/869,335 patent/US20110065698A1/en not_active Abandoned
- 2010-08-26 KR KR1020127007386A patent/KR20120059571A/ko not_active Withdrawn
- 2010-08-26 AU AU2010286691A patent/AU2010286691A1/en not_active Abandoned
- 2010-08-26 WO PCT/US2010/046760 patent/WO2011025859A1/en not_active Ceased
- 2010-08-26 EP EP10749732A patent/EP2470544A1/en not_active Withdrawn
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2012
- 2012-02-23 IL IL218280A patent/IL218280A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20110065698A1 (en) | 2011-03-17 |
| IN2012DN02596A (OSRAM) | 2015-08-28 |
| AU2010286691A1 (en) | 2012-04-19 |
| IL218280A0 (en) | 2012-04-30 |
| CA2771890A1 (en) | 2011-03-03 |
| CN102596969A (zh) | 2012-07-18 |
| MX2012002426A (es) | 2012-06-27 |
| EP2470544A1 (en) | 2012-07-04 |
| BR112012004304A2 (pt) | 2016-03-15 |
| WO2011025859A1 (en) | 2011-03-03 |
| KR20120059571A (ko) | 2012-06-08 |
| SG178552A1 (en) | 2012-03-29 |
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