JP2013501722A - 前立腺癌の処置 - Google Patents
前立腺癌の処置 Download PDFInfo
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- JP2013501722A JP2013501722A JP2012523949A JP2012523949A JP2013501722A JP 2013501722 A JP2013501722 A JP 2013501722A JP 2012523949 A JP2012523949 A JP 2012523949A JP 2012523949 A JP2012523949 A JP 2012523949A JP 2013501722 A JP2013501722 A JP 2013501722A
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Landscapes
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Applications Claiming Priority (5)
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| US23225709P | 2009-08-07 | 2009-08-07 | |
| US61/232,257 | 2009-08-07 | ||
| US26126509P | 2009-11-13 | 2009-11-13 | |
| US61/261,265 | 2009-11-13 | ||
| PCT/US2010/044570 WO2011017534A2 (en) | 2009-08-07 | 2010-08-05 | Treatment of prostate cancer |
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| JP (2) | JP2013501722A (OSRAM) |
| KR (1) | KR20120056267A (OSRAM) |
| AU (1) | AU2010279398A1 (OSRAM) |
| BR (1) | BR112012002797A2 (OSRAM) |
| CA (1) | CA2770092A1 (OSRAM) |
| WO (1) | WO2011017534A2 (OSRAM) |
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| US20100048914A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal Cyp17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| US8785423B2 (en) * | 2008-04-14 | 2014-07-22 | University Of Maryland, Baltimore | Compositions and methods of inducing endoplasmic reticulum stress response for the treatment of cell proliferative diseases |
| BRPI1008745A2 (pt) | 2009-02-05 | 2019-09-17 | Tokai Pharmaceuticals Inc | pró-fármacos de inibidores esteroidais de cyp17/antiandrogênios |
| KR101360725B1 (ko) | 2009-06-26 | 2014-02-07 | 노파르티스 아게 | Cyp17의 억제제로서의 1,3-이치환된 이미다졸리딘-2-온 유도체 |
| US8791094B2 (en) | 2009-08-07 | 2014-07-29 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
| JP6002210B2 (ja) | 2011-04-28 | 2016-10-05 | ノバルティス アーゲー | 17α−ヒドロキシラーゼ/C17,20−リアーゼ阻害剤 |
| BR112014001440A2 (pt) * | 2011-07-18 | 2017-02-21 | Tokai Pharmaceuticals Inc | novas composições e métodos para o tratamento de câncer de próstata |
| US20130203615A1 (en) * | 2011-08-05 | 2013-08-08 | Gen-Probe Incorporated | Antiandrogen therapy monitoring methods and compositions |
| WO2013071177A1 (en) * | 2011-11-10 | 2013-05-16 | Tokai Pharmaceuticals, Inc. | Methods and compositions for inhibition of androgen receptor activity |
| SG11201507093WA (en) | 2013-03-14 | 2015-10-29 | Univ Maryland Baltimore Office Of Technology Transfer | Androgen receptor down-regulating agents and uses thereof |
| CA2920317A1 (en) | 2013-08-12 | 2015-02-19 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
| WO2015170336A1 (en) | 2014-05-09 | 2015-11-12 | Council Of Scientific & Industrial Research | 16α-HETEROARYL PREGNENOLONE ACETATE AND A PROCESS FOR PREPARATION THEREOF |
| CN105732759A (zh) * | 2015-01-29 | 2016-07-06 | 苏州晶云药物科技有限公司 | (3β)-17-(1H-苯并咪唑-1-基)雄甾-5,16-二烯-3-醇的盐及其制备方法 |
| ITUA20164043A1 (it) * | 2016-06-01 | 2017-12-01 | Ind Chimica Srl | Processo per la preparazione di 3β-idrossi-17-(1H-benzimidazol-1-il)androsta-5,16-diene |
| WO2017208132A1 (en) * | 2016-06-01 | 2017-12-07 | Industriale Chimica S.R.L. | Process for the preparation of galeterone |
| WO2019241580A1 (en) * | 2018-06-14 | 2019-12-19 | Astrazeneca Uk Limited | Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition |
| WO2020223174A1 (en) * | 2019-04-27 | 2020-11-05 | Health Research, Inc. | Coumarin-modified androgens for the treatment of prostate cancer |
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| JP2008536807A (ja) * | 2005-03-02 | 2008-09-11 | ユニバーシティ、オブ、メリーランド | 新規なc−17−ヘテロアリールステロイドcyp17阻害剤/抗アンドロゲン:合成、インビトロ生物活性、薬物動態および抗腫瘍活性 |
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| CH621803A5 (OSRAM) * | 1974-08-08 | 1981-02-27 | Siphar Sa | |
| US5604213A (en) * | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| AU6823694A (en) * | 1993-04-30 | 1994-11-21 | Pacific Northwest Research Foundation | Dna profiles as an indicator of cellular redox potential and cancer risk |
| US5994335A (en) * | 1997-10-17 | 1999-11-30 | The University Of Maryland, Baltimore | 17-azolyl steroids useful as androgen synthesis inhibitors |
| US20030054053A1 (en) * | 2001-09-20 | 2003-03-20 | Charles Young | Methods and compositions for inhibiting the proliferation of prostate cancer cells |
| DK1660115T3 (da) | 2003-07-29 | 2011-10-10 | Dompe Spa | Farmaceutisk kombination af G-CSF og PLGF anvendelig til blodstamceller |
| JP4585201B2 (ja) * | 2004-01-23 | 2010-11-24 | 丸善製薬株式会社 | アンドロゲン受容体結合阻害剤、養毛剤、皮脂分泌抑制剤及び前立腺肥大抑制剤 |
| WO2008154382A1 (en) * | 2007-06-06 | 2008-12-18 | University Of Maryland, Baltimore | Hdac inhibitors and hormone targeted drugs for the treatment of cancer |
| US20100048914A1 (en) * | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal Cyp17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| US8791094B2 (en) | 2009-08-07 | 2014-07-29 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
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| JP2008536807A (ja) * | 2005-03-02 | 2008-09-11 | ユニバーシティ、オブ、メリーランド | 新規なc−17−ヘテロアリールステロイドcyp17阻害剤/抗アンドロゲン:合成、インビトロ生物活性、薬物動態および抗腫瘍活性 |
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| JPN6014031817; Tadas Vasaitis, et al.: 'Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyas' Mol Cancer Ther 7(8), 2008, 2348-57 * |
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| CA2770092A1 (en) | 2011-02-10 |
| BR112012002797A2 (pt) | 2019-09-24 |
| WO2011017534A3 (en) | 2011-06-30 |
| AU2010279398A1 (en) | 2012-03-08 |
| US20170157148A1 (en) | 2017-06-08 |
| US20150166599A1 (en) | 2015-06-18 |
| KR20120056267A (ko) | 2012-06-01 |
| US9156878B2 (en) | 2015-10-13 |
| US20140343024A1 (en) | 2014-11-20 |
| US20150203528A1 (en) | 2015-07-23 |
| WO2011017534A2 (en) | 2011-02-10 |
| JP2016074687A (ja) | 2016-05-12 |
| US8791094B2 (en) | 2014-07-29 |
| EP2461814A4 (en) | 2012-12-05 |
| US20110034428A1 (en) | 2011-02-10 |
| EP2461814A2 (en) | 2012-06-13 |
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