JP2013501722A5 - - Google Patents
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- Publication number
- JP2013501722A5 JP2013501722A5 JP2012523949A JP2012523949A JP2013501722A5 JP 2013501722 A5 JP2013501722 A5 JP 2013501722A5 JP 2012523949 A JP2012523949 A JP 2012523949A JP 2012523949 A JP2012523949 A JP 2012523949A JP 2013501722 A5 JP2013501722 A5 JP 2013501722A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- compound
- subject
- formulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 150000001875 compounds Chemical class 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 102000001307 androgen receptors Human genes 0.000 claims 4
- 108010080146 androgen receptors Proteins 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 230000001404 mediated effect Effects 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 201000004384 Alopecia Diseases 0.000 claims 1
- 208000000103 Anorexia Nervosa Diseases 0.000 claims 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010020112 Hirsutism Diseases 0.000 claims 1
- 206010054834 Hypergonadism Diseases 0.000 claims 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 231100000360 alopecia Toxicity 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- -1 glidants Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 239000002966 varnish Substances 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23225709P | 2009-08-07 | 2009-08-07 | |
| US61/232,257 | 2009-08-07 | ||
| US26126509P | 2009-11-13 | 2009-11-13 | |
| US61/261,265 | 2009-11-13 | ||
| PCT/US2010/044570 WO2011017534A2 (en) | 2009-08-07 | 2010-08-05 | Treatment of prostate cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015221564A Division JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013501722A JP2013501722A (ja) | 2013-01-17 |
| JP2013501722A5 true JP2013501722A5 (OSRAM) | 2013-09-19 |
Family
ID=43535282
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523949A Pending JP2013501722A (ja) | 2009-08-07 | 2010-08-05 | 前立腺癌の処置 |
| JP2015221564A Pending JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015221564A Pending JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US8791094B2 (OSRAM) |
| EP (1) | EP2461814A4 (OSRAM) |
| JP (2) | JP2013501722A (OSRAM) |
| KR (1) | KR20120056267A (OSRAM) |
| AU (1) | AU2010279398A1 (OSRAM) |
| BR (1) | BR112012002797A2 (OSRAM) |
| CA (1) | CA2770092A1 (OSRAM) |
| WO (1) | WO2011017534A2 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100048524A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| US8785423B2 (en) * | 2008-04-14 | 2014-07-22 | University Of Maryland, Baltimore | Compositions and methods of inducing endoplasmic reticulum stress response for the treatment of cell proliferative diseases |
| CN102686600A (zh) | 2009-02-05 | 2012-09-19 | 托凯药业股份有限公司 | 甾体cyp17抑制剂/抗雄激素物质的新型药物前体 |
| WO2010149755A1 (en) | 2009-06-26 | 2010-12-29 | Novartis Ag | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17 |
| AU2010279398A1 (en) | 2009-08-07 | 2012-03-08 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
| AU2012249421B9 (en) | 2011-04-28 | 2015-10-22 | Novartis Ag | 17alpha-hydroxylase/C17,20-lyase inhibitors |
| CN103813794A (zh) * | 2011-07-18 | 2014-05-21 | 拓凯制药公司 | 用于治疗前列腺癌的新型组合物及方法 |
| US20130203615A1 (en) * | 2011-08-05 | 2013-08-08 | Gen-Probe Incorporated | Antiandrogen therapy monitoring methods and compositions |
| WO2013071177A1 (en) * | 2011-11-10 | 2013-05-16 | Tokai Pharmaceuticals, Inc. | Methods and compositions for inhibition of androgen receptor activity |
| CA2904170A1 (en) * | 2013-03-14 | 2014-09-25 | University Of Maryland, Baltimore | Androgen receptor down-regulating agents and uses thereof |
| JP2016528252A (ja) | 2013-08-12 | 2016-09-15 | トーカイ ファーマシューティカルズ, インコーポレイテッド | アンドロゲン標的治療を使用する新生物障害の処置のためのバイオマーカー |
| WO2015170336A1 (en) | 2014-05-09 | 2015-11-12 | Council Of Scientific & Industrial Research | 16α-HETEROARYL PREGNENOLONE ACETATE AND A PROCESS FOR PREPARATION THEREOF |
| CN105732759A (zh) * | 2015-01-29 | 2016-07-06 | 苏州晶云药物科技有限公司 | (3β)-17-(1H-苯并咪唑-1-基)雄甾-5,16-二烯-3-醇的盐及其制备方法 |
| CH714035B1 (it) * | 2016-06-01 | 2021-02-15 | Ind Chimica Srl | Processo per la preparazione di 3Beta-idrossi-17-(1H-benzimidazol-1-il)androsta-5,16-diene. |
| ITUA20164043A1 (it) * | 2016-06-01 | 2017-12-01 | Ind Chimica Srl | Processo per la preparazione di 3β-idrossi-17-(1H-benzimidazol-1-il)androsta-5,16-diene |
| CA3103679A1 (en) * | 2018-06-14 | 2019-12-19 | Astrazeneca Uk Limited | Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition |
| CA3138176A1 (en) * | 2019-04-27 | 2020-11-05 | Health Research, Inc. | Coumarin-modified androgens for the treatment of prostate cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH621803A5 (OSRAM) * | 1974-08-08 | 1981-02-27 | Siphar Sa | |
| US5604213A (en) * | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| CA2161531A1 (en) * | 1993-04-30 | 1994-11-10 | Donald C. Malins | Dna profiles as an indicator of cellular redox potential and cancer risk |
| US5994335A (en) * | 1997-10-17 | 1999-11-30 | The University Of Maryland, Baltimore | 17-azolyl steroids useful as androgen synthesis inhibitors |
| US20030054053A1 (en) * | 2001-09-20 | 2003-03-20 | Charles Young | Methods and compositions for inhibiting the proliferation of prostate cancer cells |
| ATE513555T1 (de) | 2003-07-29 | 2011-07-15 | Dompe Spa | Pharmazeutische kombination aus g-csf und plgf für blutstammzellen |
| JP4585201B2 (ja) * | 2004-01-23 | 2010-11-24 | 丸善製薬株式会社 | アンドロゲン受容体結合阻害剤、養毛剤、皮脂分泌抑制剤及び前立腺肥大抑制剤 |
| NZ561571A (en) * | 2005-03-02 | 2009-09-25 | Univ Maryland | Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity |
| WO2008154382A1 (en) * | 2007-06-06 | 2008-12-18 | University Of Maryland, Baltimore | Hdac inhibitors and hormone targeted drugs for the treatment of cancer |
| US20100048524A1 (en) * | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| AU2010279398A1 (en) | 2009-08-07 | 2012-03-08 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
-
2010
- 2010-08-05 AU AU2010279398A patent/AU2010279398A1/en not_active Abandoned
- 2010-08-05 JP JP2012523949A patent/JP2013501722A/ja active Pending
- 2010-08-05 KR KR1020127006009A patent/KR20120056267A/ko not_active Ceased
- 2010-08-05 CA CA2770092A patent/CA2770092A1/en not_active Abandoned
- 2010-08-05 EP EP10807167A patent/EP2461814A4/en not_active Withdrawn
- 2010-08-05 BR BR112012002797A patent/BR112012002797A2/pt not_active IP Right Cessation
- 2010-08-05 WO PCT/US2010/044570 patent/WO2011017534A2/en not_active Ceased
- 2010-08-05 US US12/851,070 patent/US8791094B2/en not_active Expired - Fee Related
-
2014
- 2014-06-24 US US14/313,894 patent/US9156878B2/en not_active Expired - Fee Related
-
2015
- 2015-03-02 US US14/635,469 patent/US20150166599A1/en not_active Abandoned
- 2015-03-02 US US14/635,415 patent/US20150203528A1/en not_active Abandoned
- 2015-11-11 JP JP2015221564A patent/JP2016074687A/ja active Pending
-
2017
- 2017-02-23 US US15/440,623 patent/US20170157148A1/en not_active Abandoned
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