JP2013234194A5 - - Google Patents
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- Publication number
- JP2013234194A5 JP2013234194A5 JP2013153374A JP2013153374A JP2013234194A5 JP 2013234194 A5 JP2013234194 A5 JP 2013234194A5 JP 2013153374 A JP2013153374 A JP 2013153374A JP 2013153374 A JP2013153374 A JP 2013153374A JP 2013234194 A5 JP2013234194 A5 JP 2013234194A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- magunesato
- iii
- magnesium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 4
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 3
- 229910052749 magnesium Inorganic materials 0.000 claims 3
- 239000011777 magnesium Substances 0.000 claims 3
- UQRKYTFOFYASRJ-UHFFFAOYSA-N [Mg].BrBr Chemical group [Mg].BrBr UQRKYTFOFYASRJ-UHFFFAOYSA-N 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000006198 methoxylation reaction Methods 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 claims 2
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical group [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims 1
- 229910052744 lithium Inorganic materials 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 0 *C(CC1O)(c(cc2Cc3cc4ccccc4[s]3)ccc2F)OC(CO)C1O Chemical compound *C(CC1O)(c(cc2Cc3cc4ccccc4[s]3)ccc2F)OC(CO)C1O 0.000 description 1
- AHFWIQIYAXSLBA-UHFFFAOYSA-N OCC(C(C(C1O)O)O)OC1c(cc1Cc2cc(cccc3)c3[s]2)ccc1F Chemical compound OCC(C(C(C1O)O)O)OC1c(cc1Cc2cc(cccc3)c3[s]2)ccc1F AHFWIQIYAXSLBA-UHFFFAOYSA-N 0.000 description 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013153374A JP5646706B2 (ja) | 2013-07-24 | 2013-07-24 | Ｃ−グリコシド誘導体の製造方法 |
| PCT/JP2014/068386 WO2015012110A1 (ja) | 2013-07-24 | 2014-07-10 | Ｃ－グリコシド誘導体の製造方法 |
| TW103125071A TW201602128A (zh) | 2013-07-24 | 2014-07-22 | Ｃ－糖苷衍生物之製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013153374A JP5646706B2 (ja) | 2013-07-24 | 2013-07-24 | Ｃ−グリコシド誘導体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013234194A JP2013234194A (ja) | 2013-11-21 |
| JP2013234194A5 true JP2013234194A5 (enExample) | 2014-10-30 |
| JP5646706B2 JP5646706B2 (ja) | 2014-12-24 |
Family
ID=49760574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013153374A Expired - Fee Related JP5646706B2 (ja) | 2013-07-24 | 2013-07-24 | Ｃ−グリコシド誘導体の製造方法 |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP5646706B2 (enExample) |
| TW (1) | TW201602128A (enExample) |
| WO (1) | WO2015012110A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9902751B2 (en) | 2013-12-30 | 2018-02-27 | Mylan Laboratories Limited | Process for the preparation of empagliflozin |
| CN106188022A (zh) * | 2015-04-30 | 2016-12-07 | 上海医药工业研究院 | 伊格列净的制备方法 |
| WO2020129899A1 (ja) * | 2018-12-17 | 2020-06-25 | 株式会社トクヤマ | Ｃ－アリールヒドロキシグリコキシド誘導体の製造方法 |
| JP2022028986A (ja) * | 2018-12-17 | 2022-02-17 | 株式会社トクヤマ | Ｃ－アリールヒドロキシグリコキシド誘導体の製造方法 |
| WO2022107463A1 (ja) | 2020-11-18 | 2022-05-27 | 株式会社トクヤマ | ケトン誘導体の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2363941T3 (es) * | 2003-03-14 | 2011-08-19 | Astellas Pharma Inc. | Derivados de c-glucósido para el tratamiento de diabetes. |
| US8198464B2 (en) * | 2006-12-21 | 2012-06-12 | Astellas Pharma Inc. | Method for producing C-glycoside derivative and intermediate for synthesis thereof |
| EP2125768A1 (en) * | 2007-02-21 | 2009-12-02 | Boehringer Ingelheim International GmbH | Tetrasubstituted glucopyranosylated benzene derivatives, medicaments containing such compounds, their use and process for their manufacture |
| MX2011000637A (es) * | 2008-07-15 | 2011-05-02 | Theracos Inc | Derivados deuretados de bencilbenceno y metodos de uso. |
-
2013
- 2013-07-24 JP JP2013153374A patent/JP5646706B2/ja not_active Expired - Fee Related
-
2014
- 2014-07-10 WO PCT/JP2014/068386 patent/WO2015012110A1/ja not_active Ceased
- 2014-07-22 TW TW103125071A patent/TW201602128A/zh unknown