JP2013179943A5 - - Google Patents
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- JP2013179943A5 JP2013179943A5 JP2013089445A JP2013089445A JP2013179943A5 JP 2013179943 A5 JP2013179943 A5 JP 2013179943A5 JP 2013089445 A JP2013089445 A JP 2013089445A JP 2013089445 A JP2013089445 A JP 2013089445A JP 2013179943 A5 JP2013179943 A5 JP 2013179943A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- influenza
- amino acid
- acid substitution
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37567502P | 2002-04-26 | 2002-04-26 | |
| US60/375,675 | 2002-04-26 | ||
| US39498302P | 2002-07-09 | 2002-07-09 | |
| US60/394,983 | 2002-07-09 | ||
| US41057602P | 2002-09-12 | 2002-09-12 | |
| US60/410,576 | 2002-09-12 | ||
| US41980202P | 2002-10-18 | 2002-10-18 | |
| US60/419,802 | 2002-10-18 | ||
| US42070802P | 2002-10-23 | 2002-10-23 | |
| US60/420,708 | 2002-10-23 | ||
| US45769903P | 2003-03-24 | 2003-03-24 | |
| US60/457,699 | 2003-03-24 | ||
| US46236103P | 2003-04-10 | 2003-04-10 | |
| US60/462,361 | 2003-04-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011103852A Division JP5303603B2 (ja) | 2002-04-26 | 2011-05-06 | インフルエンザウイルスの生産用多重プラスミドシステム |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013131951A Division JP2013230156A (ja) | 2002-04-26 | 2013-06-24 | インフルエンザウイルスの生産用多重プラスミドシステム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013179943A JP2013179943A (ja) | 2013-09-12 |
| JP2013179943A5 true JP2013179943A5 (https=) | 2013-11-21 |
Family
ID=29273967
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003587937A Withdrawn JP2005523698A (ja) | 2002-04-26 | 2003-04-25 | インフルエンザウイルスの生産用多重プラスミドシステム |
| JP2011103852A Expired - Lifetime JP5303603B2 (ja) | 2002-04-26 | 2011-05-06 | インフルエンザウイルスの生産用多重プラスミドシステム |
| JP2013089445A Pending JP2013179943A (ja) | 2002-04-26 | 2013-04-22 | インフルエンザウイルスの生産用多重プラスミドシステム |
| JP2013131951A Pending JP2013230156A (ja) | 2002-04-26 | 2013-06-24 | インフルエンザウイルスの生産用多重プラスミドシステム |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003587937A Withdrawn JP2005523698A (ja) | 2002-04-26 | 2003-04-25 | インフルエンザウイルスの生産用多重プラスミドシステム |
| JP2011103852A Expired - Lifetime JP5303603B2 (ja) | 2002-04-26 | 2011-05-06 | インフルエンザウイルスの生産用多重プラスミドシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013131951A Pending JP2013230156A (ja) | 2002-04-26 | 2013-06-24 | インフルエンザウイルスの生産用多重プラスミドシステム |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8012736B2 (https=) |
| EP (2) | EP1499348B1 (https=) |
| JP (4) | JP2005523698A (https=) |
| KR (2) | KR101169468B1 (https=) |
| CN (4) | CN1678345A (https=) |
| AR (2) | AR039465A1 (https=) |
| AU (2) | AU2003231083A1 (https=) |
| CA (1) | CA2482946C (https=) |
| DK (1) | DK1499348T3 (https=) |
| ES (1) | ES2526191T3 (https=) |
| TW (2) | TWI347363B (https=) |
| WO (1) | WO2003091401A2 (https=) |
Families Citing this family (85)
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| MXPA02010642A (es) * | 2000-04-28 | 2004-05-17 | St Jude Children S Res Hospital | Sistema de transfeccion de adn para la generacion de virus de influenza infeccioso. |
| ATE490267T1 (de) | 2001-06-05 | 2010-12-15 | Curevac Gmbh | Stabilisierte mrna mit erhöhtem g/c-gehalt, kodierend für ein virales antigen |
| ES2526191T3 (es) | 2002-04-26 | 2015-01-08 | Medimmune, Llc | Método para producir virus influenza B infeccioso en cultivo celular |
| US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
| US7262045B2 (en) | 2003-02-25 | 2007-08-28 | Medimmune Vaccines, Inc. | Methods of producing influenza vaccine compositions |
| US20060110406A1 (en) | 2003-02-25 | 2006-05-25 | Medimmune Vaccines, Inc. | Refrigerator-temperature stable influenza vaccine compositions |
| KR20060026854A (ko) * | 2003-05-28 | 2006-03-24 | 위스콘신 얼럼나이 리서어치 화운데이션 | PolⅡ 프로모터 및 리보자임을 갖는 재조합 인플루엔자벡터 |
| US7566458B2 (en) | 2003-06-16 | 2009-07-28 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
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| EP1797189A4 (en) * | 2004-09-02 | 2010-05-19 | Qun Chen | ENCAPSIDATION SYSTEM FOR THE PRODUCTION OF RECOMBINANT VIRUSELY PARTICLES |
| JP2008512443A (ja) * | 2004-09-09 | 2008-04-24 | カイロン ベーリング ゲーエムベーハー アンド カンパニー | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| RU2420577C2 (ru) * | 2004-11-11 | 2011-06-10 | Эбботт Байолоджикалз Б.В. | Условно дефектная частица вируса гриппа и способы ее получения (варианты) |
| AU2005303817B8 (en) * | 2004-11-11 | 2010-09-30 | Abbott Biologicals B.V. | Defective influenza virus particles |
| CN101103103A (zh) | 2004-11-19 | 2008-01-09 | 威斯康星旧生研究基金会 | 具有串联转录单位的重组流感病毒载体 |
| ES2536745T3 (es) | 2004-12-08 | 2015-05-28 | Medimmune, Llc | Métodos de producción de composiciones de vacuna contra la gripe |
| ATE547511T1 (de) | 2004-12-23 | 2012-03-15 | Medimmune Llc | Nichttumorbildende mdck-zellinie zur vermehrung von viren |
| EP2295542B1 (en) * | 2004-12-24 | 2013-01-30 | Abbott Biologicals B.V. | Rescue of influenza virus |
| EP2441471B1 (en) | 2005-03-08 | 2014-10-08 | MedImmune, LLC | Reassortant influenza viruses |
| US11865172B2 (en) | 2005-04-21 | 2024-01-09 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
| US7959929B2 (en) | 2005-04-21 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
| RU2008101367A (ru) | 2005-06-21 | 2009-08-10 | Медиммун, Ллк (Us) | Способы и композиции для экспрессии отрицательной смысловой вирусной рнк в собачьих клетках |
| US8354114B2 (en) * | 2005-10-17 | 2013-01-15 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
| ES2496315T3 (es) * | 2005-10-19 | 2014-09-18 | University Of Florida Research Foundation, Incorporated | Materiales para el control de la enfermedad respiratoria en caninos |
| CA2627971A1 (en) | 2005-11-01 | 2007-05-10 | Novartis Vaccines And Diagnostics Gmbh & Co Kg. | Cell-derived viral vaccines with low levels of residual cell dna by beta-propiolactone treatment |
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| WO2007126810A2 (en) * | 2006-03-31 | 2007-11-08 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
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| US7507411B2 (en) * | 2006-06-23 | 2009-03-24 | University Of Saskatchewan | Attenuated influenza NS1 variants |
| WO2008133701A1 (en) * | 2006-07-21 | 2008-11-06 | Medimmune, Llc. | Methods and compositions for increasing replication capacity of an influenza virus |
| EP2056872A4 (en) * | 2006-08-09 | 2016-12-21 | Medimmune Llc | INFLUENZA HEMAGGLUTININE AND NEURAMINIDASE VARIANTS |
| WO2008105931A2 (en) | 2006-09-15 | 2008-09-04 | Medimmune Vaccines, Inc. | Mdck cell lines supporting viral growth to high titers and bioreactor process using the same |
| WO2008156778A2 (en) | 2007-06-18 | 2008-12-24 | Tokiko Watanabe | Influenza m2 protein mutant viruses as live influenza attenuated vaccines |
| CA2690196A1 (en) | 2007-06-18 | 2008-12-24 | Medimmune, Llc | Influenza b viruses having alterations in the hemaglutinin polypeptide |
| EP2045323A1 (en) * | 2007-10-05 | 2009-04-08 | Avir Green Hills Biotechnology Research Development Trade Ag | Linear expression constructs for production of influenza virus particles |
| EP2217064A4 (en) * | 2007-11-12 | 2012-10-03 | Univ Pennsylvania | NEW VACCINES FOR FIGHT AGAINST SEVERAL SUBTYPES OF INFLUENZA VIRUSES |
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| JP5686741B2 (ja) | 2008-12-16 | 2015-03-18 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | インフルエンザワクチンの生成 |
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| EP2493912B1 (en) | 2009-10-26 | 2020-07-29 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in vero cells |
| KR101183199B1 (ko) | 2009-11-16 | 2012-09-14 | (주)지노믹트리 | 지노타이핑 방법 |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
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| CN102864127A (zh) * | 2011-09-08 | 2013-01-09 | 中国农业科学院上海兽医研究所 | 高效表达ha蛋白的重组流感病毒及其制备方法和应用 |
| CN102851258A (zh) * | 2011-09-08 | 2013-01-02 | 中国农业科学院上海兽医研究所 | 高效表达ha蛋白的重组流感病毒及其制备方法和应用 |
| US9017694B2 (en) | 2011-10-07 | 2015-04-28 | Medimmune, Llc | Swine influenza hemagglutinin variants |
| US11028408B2 (en) | 2012-05-25 | 2021-06-08 | University Of Maryland, College Park | Recombinant influenza viruses and constructs and uses thereof |
| KR101443983B1 (ko) * | 2012-12-04 | 2014-11-03 | 충북대학교 산학협력단 | Mdck 세포 특이적으로 증식성이 향상된 다중 돌연변이 인플루엔자 a 바이러스 |
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| CN104592367B (zh) * | 2014-12-24 | 2019-01-18 | 中国科学院微生物研究所 | 流感病毒np蛋白突变体及其编码基因与应用 |
| US10323231B2 (en) | 2015-04-24 | 2019-06-18 | University Of Rochester | Attenuated influenza vaccines and uses thereof |
| US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
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| US11596683B2 (en) | 2016-07-12 | 2023-03-07 | Duke University | Engineered influenza polynucleotides, viruses, vaccines and methods of making and using the same |
| WO2019084310A1 (en) | 2017-10-25 | 2019-05-02 | Yoshihiro Kawaoka | HAS RECOMBINANT INFLUENZA VIRUSES STABILIZED FOR EGG REPLICATION |
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| CN111363017B (zh) * | 2018-12-25 | 2022-03-15 | 中国科学院微生物研究所 | A型流感病毒核蛋白s69位突变序列及其突变体与应用 |
| US11241492B2 (en) | 2019-01-23 | 2022-02-08 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to genes in influenza viruses |
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-
2003
- 2003-04-25 ES ES03724208.8T patent/ES2526191T3/es not_active Expired - Lifetime
- 2003-04-25 CN CNA038151952A patent/CN1678345A/zh active Granted
- 2003-04-25 AU AU2003231083A patent/AU2003231083A1/en not_active Abandoned
- 2003-04-25 US US10/423,828 patent/US8012736B2/en active Active
- 2003-04-25 CN CN201310365550.9A patent/CN103540613A/zh active Pending
- 2003-04-25 JP JP2003587937A patent/JP2005523698A/ja not_active Withdrawn
- 2003-04-25 WO PCT/US2003/012728 patent/WO2003091401A2/en not_active Ceased
- 2003-04-25 KR KR20047017199A patent/KR101169468B1/ko not_active Expired - Lifetime
- 2003-04-25 EP EP03724208.8A patent/EP1499348B1/en not_active Expired - Lifetime
- 2003-04-25 KR KR1020117011414A patent/KR101229202B1/ko not_active Expired - Lifetime
- 2003-04-25 CN CN038151952A patent/CN1678345B/zh not_active Expired - Fee Related
- 2003-04-25 CA CA 2482946 patent/CA2482946C/en not_active Expired - Lifetime
- 2003-04-25 EP EP20120168901 patent/EP2497826A1/en not_active Withdrawn
- 2003-04-25 DK DK03724208.8T patent/DK1499348T3/en active
- 2003-04-25 CN CN201310364981.3A patent/CN103540568A/zh active Pending
- 2003-04-28 AR ARP030101459 patent/AR039465A1/es active IP Right Grant
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- 2003-10-28 TW TW92109896A patent/TWI338047B/zh not_active IP Right Cessation
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- 2009-10-09 AU AU2009225296A patent/AU2009225296B2/en not_active Ceased
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- 2013-04-22 JP JP2013089445A patent/JP2013179943A/ja active Pending
- 2013-06-24 JP JP2013131951A patent/JP2013230156A/ja active Pending
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