JP2013177388A5 - - Google Patents
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- Publication number
- JP2013177388A5 JP2013177388A5 JP2013042001A JP2013042001A JP2013177388A5 JP 2013177388 A5 JP2013177388 A5 JP 2013177388A5 JP 2013042001 A JP2013042001 A JP 2013042001A JP 2013042001 A JP2013042001 A JP 2013042001A JP 2013177388 A5 JP2013177388 A5 JP 2013177388A5
- Authority
- JP
- Japan
- Prior art keywords
- insulin
- receptor
- composition according
- embryonic stem
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000003746 Insulin Receptor Human genes 0.000 claims 7
- 108010001127 Insulin Receptor Proteins 0.000 claims 7
- 210000001671 embryonic stem cell Anatomy 0.000 claims 7
- 102000004584 Somatomedin Receptors Human genes 0.000 claims 4
- 108010017622 Somatomedin Receptors Proteins 0.000 claims 4
- 230000004913 activation Effects 0.000 claims 3
- 210000002242 embryoid body Anatomy 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 claims 2
- 102000013275 Somatomedins Human genes 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000002161 motor neuron Anatomy 0.000 claims 2
- 102000038455 IGF Type 1 Receptor Human genes 0.000 claims 1
- 108010031794 IGF Type 1 Receptor Proteins 0.000 claims 1
- 102000038460 IGF Type 2 Receptor Human genes 0.000 claims 1
- 108010031792 IGF Type 2 Receptor Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 1
- 230000035578 autophosphorylation Effects 0.000 claims 1
- 210000001178 neural stem cell Anatomy 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 229930002330 retinoic acid Natural products 0.000 claims 1
- 229960001727 tretinoin Drugs 0.000 claims 1
- 230000001228 trophic effect Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73570205P | 2005-11-10 | 2005-11-10 | |
| US60/735,702 | 2005-11-10 | ||
| US84176606P | 2006-09-01 | 2006-09-01 | |
| US60/841,766 | 2006-09-01 | ||
| US85802206P | 2006-11-10 | 2006-11-10 | |
| US60/858,022 | 2006-11-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540231A Division JP5270362B2 (ja) | 2005-11-10 | 2006-11-10 | 幹細胞のｍｎｔｆ分化および成長 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013177388A JP2013177388A (ja) | 2013-09-09 |
| JP2013177388A5 true JP2013177388A5 (enExample) | 2013-12-19 |
Family
ID=38049179
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540231A Expired - Fee Related JP5270362B2 (ja) | 2005-11-10 | 2006-11-10 | 幹細胞のｍｎｔｆ分化および成長 |
| JP2013042001A Withdrawn JP2013177388A (ja) | 2005-11-10 | 2013-03-04 | 幹細胞のｍｎｔｆ分化および成長 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008540231A Expired - Fee Related JP5270362B2 (ja) | 2005-11-10 | 2006-11-10 | 幹細胞のｍｎｔｆ分化および成長 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8986676B2 (enExample) |
| EP (1) | EP1965826B1 (enExample) |
| JP (2) | JP5270362B2 (enExample) |
| CN (1) | CN101374537B (enExample) |
| AU (1) | AU2006315668B2 (enExample) |
| CA (1) | CA2626728A1 (enExample) |
| WO (1) | WO2007058982A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| CN101951942B (zh) * | 2008-02-21 | 2014-09-03 | 健能万生物制药公司 | Mntf肽组合物及使用方法 |
| JPWO2010137722A1 (ja) * | 2009-05-26 | 2012-11-15 | 武田薬品工業株式会社 | 再生医薬のスクリーニング方法 |
| US9770471B2 (en) | 2011-08-17 | 2017-09-26 | President And Fellows Of Harvard College | Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof |
| CN110684734A (zh) * | 2011-11-04 | 2020-01-14 | 纪念斯隆-凯特琳癌症中心 | 用于植入的中脑多巴胺（da）神经元 |
| CN104073468B (zh) * | 2014-07-16 | 2016-04-27 | 栾佐 | 获得人源OPCs的方法和OPCs培养基 |
| CN106459912B (zh) | 2014-11-14 | 2021-05-25 | 再生医科学股份有限公司 | 软骨细胞的无血清培养方法、及无血清培养基 |
| WO2016210123A1 (en) | 2015-06-26 | 2016-12-29 | Genervon Biopharmaceuticals, LLC | Methods of using gm604 in modulating als disease biomarkers leading to prognosis and therapeutic treatment for als disease |
| CN110381981A (zh) * | 2016-12-23 | 2019-10-25 | 健能万生物制药公司 | 在诊断和治疗阿尔茨海默病中使用gm6的方法 |
| US12364985B2 (en) * | 2018-05-11 | 2025-07-22 | Georgia Tech Research Corporation | Systems and methods for electronic surface antigen expression analysis using magnetophoresis |
| CN118853569B (zh) * | 2024-09-29 | 2025-03-04 | 星奕昂(上海)生物科技有限公司 | 一种拟胚体消化液及其在分离造血干细胞中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6841531B2 (en) * | 1996-09-27 | 2005-01-11 | Genervon Biopharmaceuticals Llc | Methods and use of motoneuronotrophic factors |
| US6309877B1 (en) * | 1996-09-27 | 2001-10-30 | Km Biotech, Inc. | Polynucleotides encoding motoneuronotrophic factors |
| US6300117B1 (en) | 1997-09-15 | 2001-10-09 | Genencor International, Inc. | Proteases from gram-positive organisms |
| AU2001263199B2 (en) | 2000-05-17 | 2004-09-16 | Asterias Biotherapeutics, Inc. | Neural progenitor cell populations |
| US7390659B2 (en) * | 2002-07-16 | 2008-06-24 | The Trustees Of Columbia University In The City Of New York | Methods for inducing differentiation of embryonic stem cells and uses thereof |
| DK1587526T3 (da) * | 2003-01-21 | 2012-02-06 | Genervon Biopharmaceuticals Llc | MNTF-peptider og sammensætninger og anvendelsesmåder |
| CA2544347A1 (en) * | 2003-11-07 | 2005-05-26 | Genervon Biopharmaceuticals Llc | Motoneuronotrophic factor gene sequences |
-
2006
- 2006-11-10 JP JP2008540231A patent/JP5270362B2/ja not_active Expired - Fee Related
- 2006-11-10 EP EP06837375.2A patent/EP1965826B1/en not_active Not-in-force
- 2006-11-10 AU AU2006315668A patent/AU2006315668B2/en not_active Ceased
- 2006-11-10 WO PCT/US2006/043874 patent/WO2007058982A2/en not_active Ceased
- 2006-11-10 CN CN200680041827.0A patent/CN101374537B/zh not_active Expired - Fee Related
- 2006-11-10 US US12/093,452 patent/US8986676B2/en not_active Expired - Fee Related
- 2006-11-10 CA CA002626728A patent/CA2626728A1/en not_active Abandoned
-
2013
- 2013-03-04 JP JP2013042001A patent/JP2013177388A/ja not_active Withdrawn
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