JP5270362B2 - 幹細胞のmntf分化および成長 - Google Patents

幹細胞のmntf分化および成長 Download PDF

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JP5270362B2
JP5270362B2 JP2008540231A JP2008540231A JP5270362B2 JP 5270362 B2 JP5270362 B2 JP 5270362B2 JP 2008540231 A JP2008540231 A JP 2008540231A JP 2008540231 A JP2008540231 A JP 2008540231A JP 5270362 B2 JP5270362 B2 JP 5270362B2
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cells
mntf
cell
peptide
protein
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JP2009515891A5 (enExample
JP2009515891A (ja
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ディーパ・エム・デシュパンデ
ダグラス・エイ・カー
プイ−ユク・ドロシー・コ
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ジェナボン バイオファーマシューティカルズ エルエルシー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008540231A 2005-11-10 2006-11-10 幹細胞のmntf分化および成長 Expired - Fee Related JP5270362B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US73570205P 2005-11-10 2005-11-10
US60/735,702 2005-11-10
US84176606P 2006-09-01 2006-09-01
US60/841,766 2006-09-01
US85802206P 2006-11-10 2006-11-10
PCT/US2006/043874 WO2007058982A2 (en) 2005-11-10 2006-11-10 Mntf differentiation and growth of stem cells
US60/858,022 2006-11-10

Related Child Applications (1)

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JP2013042001A Division JP2013177388A (ja) 2005-11-10 2013-03-04 幹細胞のmntf分化および成長

Publications (3)

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JP2009515891A JP2009515891A (ja) 2009-04-16
JP2009515891A5 JP2009515891A5 (enExample) 2009-09-03
JP5270362B2 true JP5270362B2 (ja) 2013-08-21

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JP2008540231A Expired - Fee Related JP5270362B2 (ja) 2005-11-10 2006-11-10 幹細胞のmntf分化および成長
JP2013042001A Withdrawn JP2013177388A (ja) 2005-11-10 2013-03-04 幹細胞のmntf分化および成長

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JP2013042001A Withdrawn JP2013177388A (ja) 2005-11-10 2013-03-04 幹細胞のmntf分化および成長

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US (1) US8986676B2 (enExample)
EP (1) EP1965826B1 (enExample)
JP (2) JP5270362B2 (enExample)
CN (1) CN101374537B (enExample)
AU (1) AU2006315668B2 (enExample)
CA (1) CA2626728A1 (enExample)
WO (1) WO2007058982A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3536778A1 (en) 2014-11-14 2019-09-11 Regenesis Science Co. Ltd. Method for serum-free culture of chondrocytes and serum-free culture medium

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2028268A1 (en) * 2007-08-20 2009-02-25 Université Libre De Bruxelles Generation of neuronal cells from pluripotent stem cells
CN101951942B (zh) * 2008-02-21 2014-09-03 健能万生物制药公司 Mntf肽组合物及使用方法
JPWO2010137722A1 (ja) * 2009-05-26 2012-11-15 武田薬品工業株式会社 再生医薬のスクリーニング方法
US9770471B2 (en) 2011-08-17 2017-09-26 President And Fellows Of Harvard College Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof
CN110684734A (zh) * 2011-11-04 2020-01-14 纪念斯隆-凯特琳癌症中心 用于植入的中脑多巴胺(da)神经元
CN104073468B (zh) * 2014-07-16 2016-04-27 栾佐 获得人源OPCs的方法和OPCs培养基
WO2016210123A1 (en) 2015-06-26 2016-12-29 Genervon Biopharmaceuticals, LLC Methods of using gm604 in modulating als disease biomarkers leading to prognosis and therapeutic treatment for als disease
CN110381981A (zh) * 2016-12-23 2019-10-25 健能万生物制药公司 在诊断和治疗阿尔茨海默病中使用gm6的方法
US12364985B2 (en) * 2018-05-11 2025-07-22 Georgia Tech Research Corporation Systems and methods for electronic surface antigen expression analysis using magnetophoresis
CN118853569B (zh) * 2024-09-29 2025-03-04 星奕昂(上海)生物科技有限公司 一种拟胚体消化液及其在分离造血干细胞中的应用

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US6841531B2 (en) * 1996-09-27 2005-01-11 Genervon Biopharmaceuticals Llc Methods and use of motoneuronotrophic factors
US6309877B1 (en) * 1996-09-27 2001-10-30 Km Biotech, Inc. Polynucleotides encoding motoneuronotrophic factors
US6300117B1 (en) 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
US7390659B2 (en) * 2002-07-16 2008-06-24 The Trustees Of Columbia University In The City Of New York Methods for inducing differentiation of embryonic stem cells and uses thereof
DK1587526T3 (da) * 2003-01-21 2012-02-06 Genervon Biopharmaceuticals Llc MNTF-peptider og sammensætninger og anvendelsesmåder
CA2544347A1 (en) * 2003-11-07 2005-05-26 Genervon Biopharmaceuticals Llc Motoneuronotrophic factor gene sequences

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3536778A1 (en) 2014-11-14 2019-09-11 Regenesis Science Co. Ltd. Method for serum-free culture of chondrocytes and serum-free culture medium

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Publication number Publication date
AU2006315668B2 (en) 2013-06-20
JP2013177388A (ja) 2013-09-09
EP1965826B1 (en) 2014-12-31
EP1965826A2 (en) 2008-09-10
CN101374537A (zh) 2009-02-25
HK1125824A1 (zh) 2009-08-21
US8986676B2 (en) 2015-03-24
WO2007058982A3 (en) 2008-09-25
CA2626728A1 (en) 2007-05-24
WO2007058982A2 (en) 2007-05-24
JP2009515891A (ja) 2009-04-16
AU2006315668A1 (en) 2007-05-24
US20090117085A1 (en) 2009-05-07
EP1965826A4 (en) 2010-08-25
CN101374537B (zh) 2016-04-20

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