JP2013137311A5 - - Google Patents

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Publication number
JP2013137311A5
JP2013137311A5 JP2012273726A JP2012273726A JP2013137311A5 JP 2013137311 A5 JP2013137311 A5 JP 2013137311A5 JP 2012273726 A JP2012273726 A JP 2012273726A JP 2012273726 A JP2012273726 A JP 2012273726A JP 2013137311 A5 JP2013137311 A5 JP 2013137311A5
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JP
Japan
Prior art keywords
receptor
cell
protein
transmembrane protein
nls
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Application number
JP2012273726A
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English (en)
Japanese (ja)
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JP5870016B2 (ja
JP2013137311A (ja
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Publication of JP2013137311A publication Critical patent/JP2013137311A/ja
Publication of JP2013137311A5 publication Critical patent/JP2013137311A5/ja
Application granted granted Critical
Publication of JP5870016B2 publication Critical patent/JP5870016B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2012273726A 2002-04-12 2012-12-14 膜貫通型タンパク質と相互作用する化合物の同定法 Expired - Lifetime JP5870016B2 (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US37170402P 2002-04-12 2002-04-12
US60/371,704 2002-04-12
US37941902P 2002-05-13 2002-05-13
US60/379,419 2002-05-13
US38757002P 2002-06-12 2002-06-12
US60/387,570 2002-06-12
US42289102P 2002-11-01 2002-11-01
US60/422,891 2002-11-01
US44255603P 2003-01-27 2003-01-27
US60/442,556 2003-01-27

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2009267007A Division JP5187910B2 (ja) 2002-04-12 2009-11-25 膜貫通型タンパク質と相互作用する化合物の同定法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015190891A Division JP6168669B2 (ja) 2002-04-12 2015-09-29 膜貫通型タンパク質と相互作用する化合物の同定法

Publications (3)

Publication Number Publication Date
JP2013137311A JP2013137311A (ja) 2013-07-11
JP2013137311A5 true JP2013137311A5 (https=) 2014-05-22
JP5870016B2 JP5870016B2 (ja) 2016-02-24

Family

ID=29255685

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2003584728A Expired - Lifetime JP4542342B2 (ja) 2002-04-12 2003-04-11 膜貫通型タンパク質と相互作用する化合物の同定法
JP2009267007A Expired - Lifetime JP5187910B2 (ja) 2002-04-12 2009-11-25 膜貫通型タンパク質と相互作用する化合物の同定法
JP2012273726A Expired - Lifetime JP5870016B2 (ja) 2002-04-12 2012-12-14 膜貫通型タンパク質と相互作用する化合物の同定法
JP2015190891A Expired - Lifetime JP6168669B2 (ja) 2002-04-12 2015-09-29 膜貫通型タンパク質と相互作用する化合物の同定法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2003584728A Expired - Lifetime JP4542342B2 (ja) 2002-04-12 2003-04-11 膜貫通型タンパク質と相互作用する化合物の同定法
JP2009267007A Expired - Lifetime JP5187910B2 (ja) 2002-04-12 2009-11-25 膜貫通型タンパク質と相互作用する化合物の同定法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015190891A Expired - Lifetime JP6168669B2 (ja) 2002-04-12 2015-09-29 膜貫通型タンパク質と相互作用する化合物の同定法

Country Status (16)

Country Link
US (8) US7309576B2 (https=)
EP (3) EP1495330B1 (https=)
JP (4) JP4542342B2 (https=)
CN (1) CN100399028C (https=)
AT (1) ATE421697T1 (https=)
AU (2) AU2003218586B2 (https=)
CA (1) CA2521946C (https=)
CY (1) CY1108997T1 (https=)
DE (1) DE60325953D1 (https=)
DK (1) DK1495330T3 (https=)
ES (2) ES2321704T3 (https=)
MX (1) MXPA04011134A (https=)
NZ (2) NZ536063A (https=)
PT (1) PT1495330E (https=)
SI (1) SI1495330T1 (https=)
WO (1) WO2003087836A1 (https=)

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JP4929462B2 (ja) 2007-01-29 2012-05-09 国立大学法人高知大学 細胞膜上分子と相互作用する化合物の検出方法
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CN102580091B (zh) * 2011-01-12 2014-12-10 中国科学院上海生命科学研究院 增强阿片镇痛剂的镇痛作用的方法及试剂
US8643360B1 (en) * 2012-09-02 2014-02-04 George S. Cargill, III In-water voltage gradient detector
TWI472617B (zh) * 2012-09-17 2015-02-11 Nat Univ Chung Hsing 調控大分子進入細胞內之蛋白質及其調控大分子進入細胞內之方法
US10513711B2 (en) 2014-08-13 2019-12-24 Dupont Us Holding, Llc Genetic targeting in non-conventional yeast using an RNA-guided endonuclease
JP6823593B2 (ja) 2014-11-06 2021-02-03 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ Ｒｎａ誘導型エンドヌクレアーゼの細胞へのペプチド媒介輸送
AU2016263026A1 (en) 2015-05-15 2017-11-09 Pioneer Hi-Bred International, Inc. Guide RNA/Cas endonuclease systems
EP4144844B1 (en) 2015-10-12 2025-09-10 DuPont US Holding, LLC Protected dna templates for gene modification and increased homologous recombination in cells and methods of use
BR112018008134A2 (pt) 2015-10-20 2018-11-06 Pioneer Hi Bred Int método para restaurar a função de um produto gênico não funcional no genoma de uma célula, método para editar uma sequência nucleotídica no genoma de uma célula, planta ou planta de progênie, método para editar uma sequência nucleotídica no genoma de uma célula sem o uso de um molde polinucleotídico de modificação e método para entregar um complexo de rna guia/endonuclease cas numa célula
WO2017079026A1 (en) 2015-11-06 2017-05-11 E. I. Du Pont De Nemours And Company Generation of complex trait loci in soybean and methods of use
DK3387134T3 (da) 2015-12-11 2020-12-21 Danisco Us Inc Fremgangsmåder og sammensætninger til øget nukleasemedieret genommodifikation og reducerede virkninger uden for målstedet
EP3390631B1 (en) 2015-12-18 2020-04-08 Danisco US Inc. Methods and compositions for t-rna based guide rna expression
WO2017132239A1 (en) 2016-01-26 2017-08-03 Pioneer Hi-Bred International, Inc. Waxy corn
EP3426778A1 (en) 2016-03-11 2019-01-16 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
WO2017155715A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
EP3426780A1 (en) 2016-03-11 2019-01-16 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
MX2018014993A (es) 2016-06-14 2019-09-06 Pioneer Hi Bred Int Uso de endonucleasa cpf1 para modificaciones de genoma de planta.
WO2017222773A1 (en) 2016-06-20 2017-12-28 Pioneer Hi-Bred International, Inc. Novel cas systems and methods of use
US12012605B2 (en) 2016-10-13 2024-06-18 Pioneer Hi-Bred International, Inc. Generating northern leaf blight resistant maize
US11473081B2 (en) * 2016-12-12 2022-10-18 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
JP7208902B2 (ja) 2016-12-30 2023-01-19 エクセラ・バイオサイエンシーズ・インコーポレイテッド マルチステージサンプル回収システム
WO2018129440A1 (en) 2017-01-09 2018-07-12 University Of Massachusetts Complexes for gene deletion and editing
BR112020011011A2 (pt) 2017-12-15 2020-11-17 Danisco Us Inc. variantes de cas9 e métodos de uso
CN108178790B (zh) * 2018-01-18 2021-09-07 上海药明康德新药开发有限公司 一种将细胞膜分离以便对跨膜蛋白进行dna编码化合物库筛选的方法
WO2019165168A1 (en) 2018-02-23 2019-08-29 Pioneer Hi-Bred International, Inc. Novel cas9 orthologs
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MX2021008094A (es) 2019-01-11 2021-09-21 Omeros Corp Metodos y composiciones para el tratamiento del cancer.
KR102931179B1 (ko) 2019-04-05 2026-02-25 다니스코 유에스 인크. 선형 재조합 dna 작제물 및 이의 조성물을 이용하여 공여 dna 서열을 바실러스 게놈 내에 통합시키기 위한 방법
EP3947656A1 (en) 2019-04-05 2022-02-09 Danisco US Inc. Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof
KR102329302B1 (ko) * 2019-09-30 2021-11-22 한국과학기술연구원 도파민 d1형 수용체의 활성 측정용 적색 형광 단백질 기반 바이오센서
US20250064032A1 (en) 2021-12-10 2025-02-27 Pig Improvement Company Uk Limited Editing tmprss2/4 for disease resistance in livestock
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WO2024013514A2 (en) 2022-07-15 2024-01-18 Pig Improvement Company Uk Limited Gene edited livestock animals having coronavirus resistance
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WO2002014475A2 (en) 2000-08-16 2002-02-21 The Trustees Of Columbia University In The City Of New York QUANTITATIVE ASSESSMENT OF erbB/HER RECEPTORS IN BIOLOGICAL FLUIDS
DE60325953D1 (de) 2002-04-12 2009-03-12 Brian F O'dowd Verfahren zur identifizierung von verbindungen, die transmembran-proteine beeinflussen

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