JP2013129650A5 - - Google Patents
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- Publication number
- JP2013129650A5 JP2013129650A5 JP2012247143A JP2012247143A JP2013129650A5 JP 2013129650 A5 JP2013129650 A5 JP 2013129650A5 JP 2012247143 A JP2012247143 A JP 2012247143A JP 2012247143 A JP2012247143 A JP 2012247143A JP 2013129650 A5 JP2013129650 A5 JP 2013129650A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- optionally substituted
- independently represent
- heterocyclic carbene
- substituted alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ADLVDYMTBOSDFE-UHFFFAOYSA-N 5-chloro-6-nitroisoindole-1,3-dione Chemical group C1=C(Cl)C([N+](=O)[O-])=CC2=C1C(=O)NC2=O ADLVDYMTBOSDFE-UHFFFAOYSA-N 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 125000001072 heteroaryl group Chemical group 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR11/03933 | 2011-12-20 | ||
| FR1103933A FR2984319B1 (fr) | 2011-12-20 | 2011-12-20 | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013129650A JP2013129650A (ja) | 2013-07-04 |
| JP2013129650A5 true JP2013129650A5 (enExample) | 2014-08-28 |
| JP5670406B2 JP5670406B2 (ja) | 2015-02-18 |
Family
ID=47115640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012247143A Active JP5670406B2 (ja) | 2011-12-20 | 2012-11-09 | イバブラジン及び薬学的に許容しうる酸とのその付加塩の新規合成方法 |
Country Status (34)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2988720B1 (fr) * | 2012-03-27 | 2014-03-14 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| CN105669554A (zh) * | 2016-02-22 | 2016-06-15 | 徐建立 | 一种盐酸伊伐布雷定杂质及其制备方法和应用 |
| FR3071833B1 (fr) * | 2017-09-29 | 2020-01-03 | Universite Paris-Sud | Nouveau procede de synthese d'amines tertiaires dissymetriques |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681862B1 (fr) * | 1991-09-27 | 1993-11-12 | Adir Cie | Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent. |
| US6225487B1 (en) * | 1998-04-17 | 2001-05-01 | Symyx Technologies, Inc. | Ancillary ligands and metal complexes, catalysts and compositions using same and methods of testing |
| US6521793B1 (en) * | 1998-10-08 | 2003-02-18 | Symyx Technologies, Inc. | Catalyst ligands, catalytic metal complexes and processes using same |
| FR2868777B1 (fr) * | 2004-04-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| EP1595888A1 (en) * | 2004-05-11 | 2005-11-16 | Degussa AG | Cycloolefin phosphine ligands and their use in catalysis |
| EP2097383B1 (en) * | 2006-11-30 | 2012-02-08 | Cadila Healthcare Limited | Process for preparation of ivabradine hydrochloride |
| PT2471780E (pt) * | 2007-05-30 | 2015-02-24 | Ind Swift Lab Ltd | Sais oxalato de ivabradina cristalinos e seus polimorfos |
| US7857994B2 (en) | 2007-05-30 | 2010-12-28 | GE Lighting Solutions, LLC | Green emitting phosphors and blends thereof |
| FR2920773B1 (fr) | 2007-09-11 | 2009-10-23 | Servier Lab | Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2933975B1 (fr) * | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| FR2935381B1 (fr) * | 2008-08-29 | 2010-12-17 | Servier Lab | Nouveau procede de resolution des enantiomerees du (3,4-dimethoxy-bicyclo°4.2.0!octa-1,3,5-trien-7-yl)nitrile et application a la synthese de l'ivabradine |
| FR2940287B1 (fr) * | 2008-12-24 | 2010-12-24 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| FR2941695B1 (fr) * | 2009-02-04 | 2011-02-18 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
-
2011
- 2011-12-20 FR FR1103933A patent/FR2984319B1/fr not_active Expired - Fee Related
-
2012
- 2012-10-23 SG SG2012078705A patent/SG191471A1/en unknown
- 2012-10-23 JO JOP/2012/0320A patent/JO3031B1/ar active
- 2012-10-24 AU AU2012244188A patent/AU2012244188B2/en not_active Ceased
- 2012-10-24 CA CA2795741A patent/CA2795741C/fr not_active Expired - Fee Related
- 2012-10-25 PE PE2012002077A patent/PE20131097A1/es active IP Right Grant
- 2012-10-30 ZA ZA2012/08160A patent/ZA201208160B/en unknown
- 2012-10-30 UY UY0001034423A patent/UY34423A/es not_active Application Discontinuation
- 2012-10-30 MY MYPI2012700844A patent/MY170662A/en unknown
- 2012-10-31 MD MDA20120094A patent/MD4336C1/ro not_active IP Right Cessation
- 2012-11-06 TW TW101141192A patent/TWI440627B/zh not_active IP Right Cessation
- 2012-11-07 MX MX2012012938A patent/MX2012012938A/es active IP Right Grant
- 2012-11-07 AR ARP120104179A patent/AR088678A1/es unknown
- 2012-11-07 MA MA35353A patent/MA34276B1/fr unknown
- 2012-11-08 CN CN201210443036.8A patent/CN103172566B/zh not_active Expired - Fee Related
- 2012-11-08 BR BR102012028614-9A patent/BR102012028614A2/pt not_active IP Right Cessation
- 2012-11-08 KR KR1020120126314A patent/KR101470879B1/ko not_active Expired - Fee Related
- 2012-11-08 UA UAA201212746A patent/UA111329C2/uk unknown
- 2012-11-08 GE GEAP201212889A patent/GEP20156350B/en unknown
- 2012-11-08 CL CL2012003136A patent/CL2012003136A1/es unknown
- 2012-11-09 RS RSP20140509 patent/RS53541B1/sr unknown
- 2012-11-09 EA EA201201385A patent/EA026510B1/ru not_active IP Right Cessation
- 2012-11-09 WO PCT/FR2012/000451 patent/WO2013093220A1/fr not_active Ceased
- 2012-11-09 PL PL12191902T patent/PL2607353T3/pl unknown
- 2012-11-09 US US13/673,145 patent/US8513410B2/en not_active Expired - Fee Related
- 2012-11-09 EP EP12191902.1A patent/EP2607353B1/fr active Active
- 2012-11-09 SI SI201230089T patent/SI2607353T1/sl unknown
- 2012-11-09 PT PT121919021T patent/PT2607353E/pt unknown
- 2012-11-09 DK DK12191902.1T patent/DK2607353T3/en active
- 2012-11-09 ES ES12191902.1T patent/ES2525032T3/es active Active
- 2012-11-09 JP JP2012247143A patent/JP5670406B2/ja active Active
- 2012-11-10 SA SA112330994A patent/SA112330994B1/ar unknown
-
2014
- 2014-10-14 CY CY20141100832T patent/CY1115682T1/el unknown
- 2014-10-23 HR HRP20141023AT patent/HRP20141023T1/hr unknown
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