JP2013082720A5 - - Google Patents
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- Publication number
- JP2013082720A5 JP2013082720A5 JP2012272243A JP2012272243A JP2013082720A5 JP 2013082720 A5 JP2013082720 A5 JP 2013082720A5 JP 2012272243 A JP2012272243 A JP 2012272243A JP 2012272243 A JP2012272243 A JP 2012272243A JP 2013082720 A5 JP2013082720 A5 JP 2013082720A5
- Authority
- JP
- Japan
- Prior art keywords
- oxybutynin
- drug
- transdermal
- administered
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 description 11
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 description 10
- 229940079593 drug Drugs 0.000 description 10
- 229960005434 oxybutynin Drugs 0.000 description 9
- 230000036470 plasma concentration Effects 0.000 description 7
- 239000000203 mixture Substances 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002207 metabolite Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000002411 adverse Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 239000000902 placebo Substances 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229940100640 transdermal system Drugs 0.000 description 2
- 206010020853 Hypertonic bladder Diseases 0.000 description 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 230000001078 anti-cholinergic effect Effects 0.000 description 1
- 238000011260 co-administration Methods 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 description 1
- 230000010226 intestinal metabolism Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 229940096978 oral tablet Drugs 0.000 description 1
- 208000020629 overactive bladder Diseases 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55971100A | 2000-04-26 | 2000-04-26 | |
| US09/559,711 | 2000-04-26 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001577898A Division JP2003531157A (ja) | 2000-04-26 | 2001-04-24 | オキシブチニン治療に関連した有害な経験の最小化 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016160805A Division JP6253734B2 (ja) | 2000-04-26 | 2016-08-18 | オキシブチニン治療に関連した有害な経験の最小化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013082720A JP2013082720A (ja) | 2013-05-09 |
| JP2013082720A5 true JP2013082720A5 (https=) | 2016-10-06 |
| JP6077294B2 JP6077294B2 (ja) | 2017-02-08 |
Family
ID=24234699
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001577898A Pending JP2003531157A (ja) | 2000-04-26 | 2001-04-24 | オキシブチニン治療に関連した有害な経験の最小化 |
| JP2012272243A Expired - Lifetime JP6077294B2 (ja) | 2000-04-26 | 2012-12-13 | オキシブチニン治療に関連した有害な経験の最小化 |
| JP2016160805A Expired - Lifetime JP6253734B2 (ja) | 2000-04-26 | 2016-08-18 | オキシブチニン治療に関連した有害な経験の最小化 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001577898A Pending JP2003531157A (ja) | 2000-04-26 | 2001-04-24 | オキシブチニン治療に関連した有害な経験の最小化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016160805A Expired - Lifetime JP6253734B2 (ja) | 2000-04-26 | 2016-08-18 | オキシブチニン治療に関連した有害な経験の最小化 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US6743441B2 (https=) |
| EP (3) | EP1280486B1 (https=) |
| JP (3) | JP2003531157A (https=) |
| CN (4) | CN101843601A (https=) |
| AT (1) | ATE488233T1 (https=) |
| AU (2) | AU2001253782B2 (https=) |
| BR (1) | BR0110381A (https=) |
| CA (1) | CA2406064C (https=) |
| CY (1) | CY1111498T1 (https=) |
| DE (1) | DE60143477D1 (https=) |
| DK (1) | DK1280486T3 (https=) |
| ES (1) | ES2357699T3 (https=) |
| MX (2) | MX342305B (https=) |
| PT (1) | PT1280486E (https=) |
| WO (1) | WO2001080796A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR018321A1 (es) * | 1998-03-26 | 2001-11-14 | Alza Corp | Una forma de dosificacion de liberacion prolongada que comprende oxibutinina y los usos de la oxibutinina y de la forma de dosificacion de liberacionprolongada. |
| US7029694B2 (en) * | 2000-04-26 | 2006-04-18 | Watson Laboratories, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| CN101843601A (zh) * | 2000-04-26 | 2010-09-29 | 沃特森药物公司 | 最小化与奥昔布宁疗法有关的副作用 |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
| ATE485837T1 (de) | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| JP2005513080A (ja) * | 2001-12-20 | 2005-05-12 | フェムファーマ， インコーポレイテッド | 薬物の膣送達 |
| JP4354678B2 (ja) * | 2002-08-28 | 2009-10-28 | 久光製薬株式会社 | 貼付剤 |
| US7276068B2 (en) | 2002-10-04 | 2007-10-02 | Sherwood Services Ag | Vessel sealing instrument with electrical cutting mechanism |
| AU2012216593B2 (en) * | 2002-11-01 | 2014-09-25 | Allergan Sales, Llc | Compositions and methods for transdermal oxybutynin therapy |
| JP2006515026A (ja) * | 2003-01-02 | 2006-05-18 | フェムファーマ ホールディング カンパニー， インコーポレイテッド | 乳房の疾患および障害の処置のための薬学的調製物 |
| US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
| DE10315878B4 (de) * | 2003-04-08 | 2009-06-04 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Fesoterodin und Verwendung |
| ATE534373T1 (de) | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| TW200514582A (en) * | 2003-10-31 | 2005-05-01 | Hisamitsu Pharmaceutical Co | Transdermal preparation and method for reducing side effect in pergolide therapy |
| US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
| JP5097359B2 (ja) | 2006-05-09 | 2012-12-12 | 久光製薬株式会社 | ドネペジル経皮吸収型製剤 |
| WO2008067991A2 (en) * | 2006-12-08 | 2008-06-12 | Antares Pharma Ipl Ag | Skin-friendly drug complexes for transdermal administration |
| US20080153789A1 (en) * | 2006-12-26 | 2008-06-26 | Femmepharma Holding Company, Inc. | Topical administration of danazol |
| TWI541246B (zh) | 2008-12-08 | 2016-07-11 | 歐陸斯迪公司 | 二氫羥戊甲嗎啡 |
| US8920392B2 (en) | 2009-05-05 | 2014-12-30 | Watson Laboratories, Inc. | Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions |
| US20110003000A1 (en) * | 2009-07-06 | 2011-01-06 | Femmepharma Holding Company, Inc. | Transvaginal Delivery of Drugs |
| WO2011137054A1 (en) | 2010-04-30 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
| US20160151321A1 (en) | 2012-11-13 | 2016-06-02 | Dinesh C. Patel | Methods for the treatment of sialorrhea |
| US20140135392A1 (en) * | 2012-11-13 | 2014-05-15 | NeuRx Pharmaceuticals LLC | Methods for the treatment of sialorrhea |
| GB201309654D0 (en) | 2013-05-30 | 2013-07-17 | Euro Celtique Sa | Method |
| EP3242659A4 (en) | 2015-01-09 | 2018-09-12 | Chase Pharmaceuticals Corporation | Oxybutynin transdermal therapeutic system combination |
| US20170239183A1 (en) * | 2016-02-23 | 2017-08-24 | PixarBio Corporation | COMPOSITIONS COMPRISING NAv1.7 SELECTIVE INHIBITORS FOR TREATING ACUTE, POST-OPERATIVE, OR CHRONIC PAIN AND METHODS OF USING THE SAME |
| CN110719778B (zh) | 2017-04-24 | 2024-06-18 | 才思治疗公司 | 用于治疗抑郁的组合物和方法 |
| EP3662905B1 (en) * | 2017-08-01 | 2022-05-04 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
| US20240315971A1 (en) * | 2023-03-03 | 2024-09-26 | Lotus Biopharma Inc. | Microsphere formulations and methods of preparation thereof |
Family Cites Families (57)
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|---|---|---|---|---|
| US147236A (en) * | 1874-02-10 | Improvement in devices for riveting the teeth of saws | ||
| NL124473C (https=) * | 1960-07-26 | |||
| US5736577A (en) | 1995-01-31 | 1998-04-07 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin |
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| US4959217A (en) | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
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| US5641504A (en) | 1988-06-09 | 1997-06-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolinoleate |
| EP0481007B1 (en) * | 1989-06-07 | 1997-01-22 | BAZZANO, Gail S | SLOW RELEASE VEHICLES FOR MINIMIZING SKIN IRRITANCY OF TOPICAL COMPOSITIONS containing retinoids |
| US5922342A (en) | 1990-10-01 | 1999-07-13 | Pharmacia & Upjohn Company | Lateral edge coated controlled release pharmaceutical compositions |
| US5164190A (en) * | 1990-12-11 | 1992-11-17 | Theratech, Inc. | Subsaturated transdermal drug delivery device exhibiting enhanced drug flux |
| US5152997A (en) | 1990-12-11 | 1992-10-06 | Theratech, Inc. | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels |
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| AU670777B2 (en) * | 1992-04-16 | 1996-08-01 | Ortho Pharmaceutical Corporation | Aqueous gel vehicles for retinoids |
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| JP3277342B2 (ja) | 1992-09-02 | 2002-04-22 | 武田薬品工業株式会社 | 徐放性マイクロカプセルの製造法 |
| JP3688293B2 (ja) | 1993-09-29 | 2005-08-24 | アルザ・コーポレーション | モノグリセリド／乳酸エステル透過促進剤 |
| JP3021661B2 (ja) | 1994-03-07 | 2000-03-15 | セラテック・インコーポレーテッド | 薬剤含有接着複合体の経皮放出デバイス |
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| US5635203A (en) | 1994-09-29 | 1997-06-03 | Alza Corporation | Transdermal device having decreased delamination |
| WO1996011022A1 (en) | 1994-10-05 | 1996-04-18 | Hisamitsu Pharmaceutical Co., Inc. | DRUG COMPOUNDING INGREDIENTS COMPRISING N-SUBSTITUTED-o-TOLUIDINE DERIVATIVE AND PERCUTANEOUSLY ABSORBABLE PREPARATION |
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| US5562917A (en) | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
| US5677346A (en) | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
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| US5862555A (en) | 1995-04-06 | 1999-01-26 | Furuhashi; Masanobu | System and method for manufacturing shoes using a wooden mold |
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| US5674895A (en) | 1995-05-22 | 1997-10-07 | Alza Corporation | Dosage form comprising oxybutynin |
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| IT1283102B1 (it) | 1996-06-06 | 1998-04-07 | Permatec Nv | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
| US5783208A (en) | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
| US5762953A (en) | 1996-08-22 | 1998-06-09 | Theratech, Inc. | Transdermal propentofylline compositions for the treatment of Alzheimers disease |
| US5985317A (en) | 1996-09-06 | 1999-11-16 | Theratech, Inc. | Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents |
| US5769683A (en) * | 1997-02-10 | 1998-06-23 | Park; Young-Ho | Attachment for balloon tether |
| US6203817B1 (en) | 1997-02-19 | 2001-03-20 | Alza Corporation | Reduction of skin reactions caused by transdermal drug delivery |
| US6479373B2 (en) * | 1997-02-20 | 2002-11-12 | Infineon Technologies Ag | Method of structuring layers with a polysilicon layer and an overlying metal or metal silicide layer using a three step etching process with fluorine, chlorine, bromine containing gases |
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| KR20010006027A (ko) * | 1997-04-03 | 2001-01-15 | 포인트 바이오메디칼 코퍼레이션 | 방광내 약물 송달 시스템 |
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| US5891888A (en) * | 1998-01-14 | 1999-04-06 | Strahl; Robert Charles | Physical endurance drink |
| DE29823343U1 (de) * | 1998-03-20 | 1999-07-15 | Schwarz Pharma Ag, 40789 Monheim | Transdermales Therapeutisches System (TTS) Oxybutynin enthaltend |
| AR018321A1 (es) | 1998-03-26 | 2001-11-14 | Alza Corp | Una forma de dosificacion de liberacion prolongada que comprende oxibutinina y los usos de la oxibutinina y de la forma de dosificacion de liberacionprolongada. |
| US5986305A (en) * | 1998-03-30 | 1999-11-16 | Texas Instruments - Acer Incorporated | Semiconductor device with an inverse-T gate lightly-doped drain structure |
| FR2779438B1 (fr) | 1998-06-03 | 2004-12-24 | Jean Marc Aiache | Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant |
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-
2001
- 2001-04-24 CN CN201010112972A patent/CN101843601A/zh active Pending
- 2001-04-24 EP EP01927318A patent/EP1280486B1/en not_active Expired - Lifetime
- 2001-04-24 EP EP08008334A patent/EP1992342A1/en not_active Ceased
- 2001-04-24 JP JP2001577898A patent/JP2003531157A/ja active Pending
- 2001-04-24 AU AU2001253782A patent/AU2001253782B2/en not_active Expired
- 2001-04-24 DE DE60143477T patent/DE60143477D1/de not_active Expired - Lifetime
- 2001-04-24 ES ES01927318T patent/ES2357699T3/es not_active Expired - Lifetime
- 2001-04-24 CA CA2406064A patent/CA2406064C/en not_active Expired - Lifetime
- 2001-04-24 EP EP20100184172 patent/EP2322170A1/en not_active Ceased
- 2001-04-24 CN CN01809980A patent/CN1438861A/zh active Pending
- 2001-04-24 CN CN2011102128311A patent/CN102327253A/zh active Pending
- 2001-04-24 DK DK01927318.4T patent/DK1280486T3/da active
- 2001-04-24 CN CNA2008100986227A patent/CN101305994A/zh active Pending
- 2001-04-24 AT AT01927318T patent/ATE488233T1/de active
- 2001-04-24 AU AU5378201A patent/AU5378201A/xx active Pending
- 2001-04-24 WO PCT/US2001/013135 patent/WO2001080796A1/en not_active Ceased
- 2001-04-24 PT PT01927318T patent/PT1280486E/pt unknown
- 2001-04-24 MX MX2011013180A patent/MX342305B/es unknown
- 2001-04-24 MX MXPA02010542A patent/MXPA02010542A/es active IP Right Grant
- 2001-04-24 BR BR0110381-4A patent/BR0110381A/pt not_active Application Discontinuation
-
2002
- 2002-03-15 US US10/098,752 patent/US6743441B2/en not_active Expired - Lifetime
-
2003
- 2003-12-08 US US10/731,040 patent/US7081250B2/en not_active Expired - Lifetime
- 2003-12-08 US US10/731,041 patent/US7081251B2/en not_active Expired - Lifetime
- 2003-12-08 US US10/731,824 patent/US7081252B2/en not_active Expired - Lifetime
- 2003-12-08 US US10/731,039 patent/US7081249B2/en not_active Expired - Lifetime
-
2005
- 2005-10-07 US US11/246,558 patent/US7087241B2/en not_active Expired - Lifetime
-
2011
- 2011-02-16 CY CY20111100189T patent/CY1111498T1/el unknown
-
2012
- 2012-12-13 JP JP2012272243A patent/JP6077294B2/ja not_active Expired - Lifetime
-
2016
- 2016-08-18 JP JP2016160805A patent/JP6253734B2/ja not_active Expired - Lifetime
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