JP2013024567A - Automatic analyzer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analyzer which can be prevented from being expanded in size, without polluting a portion of a reaction container washing part.SOLUTION: An automatic analyzer comprises a mechanism part 26 which moves a reaction container 3 by rotating a reaction disc 4, a reaction container washing part 12 which washes the reaction container 3 stopped at a washing position W, an auxiliary storage part 27 which stores a container number identifying the reaction container 3 stopped at a positioning position, and an operation part 50 which performs input for moving the reaction container 3 and executing operation accompanied with washing. In response to input of maintenance start or measurement start from the operation part 50, the reaction container 3 identified from a latest container number stored in the auxiliary storage part 27 is moved to the positioning position before starting washing by the reaction container washing part 12.

Description

  Embodiments described herein relate generally to an automatic analyzer that analyzes components contained in a liquid such as a sample collected from a subject.

  The automatic analyzer is intended for biochemical test items and immunological test items, and has an analysis unit that optically measures changes in color and turbidity caused by the reaction between the test sample collected from the test sample and the reagent. . Analysis data represented by the concentration and enzyme activity of various test item components in the test sample is generated by the measurement in the analysis unit.

  In the analysis unit, the test sample and reagents for each test item are dispensed into a plurality of reaction containers, and the dispensed sample and reagent mixture is measured by the photometry unit. The reaction vessel used for the measurement is repeatedly used for the measurement after being partially washed into the reaction vessel and washed in the reaction vessel washing section for washing.

  By the way, if the measurement operation is started again after a power failure or the like during the measurement operation of the analysis unit, a part of the reaction vessel cleaning unit that has entered due to residual liquid such as a mixed liquid remaining in the reaction vessel is contaminated. Is done. In order to prevent this contamination, an automatic analyzer equipped with a liquid detector that detects the presence or absence of residual liquid in a reaction vessel is known.

JP-A-11-352131

  However, the installation of the liquid detector has a problem that the configuration becomes complicated and the size is increased.

  The embodiment has been made to solve the above-described problems, and an object thereof is to provide an automatic analyzer that can prevent an increase in size without contaminating the reaction vessel cleaning unit.

  In order to achieve the above object, an automatic analyzer according to an embodiment dispenses a sample and a reagent into a reaction container, and in the automatic analyzer that measures the mixed solution, a moving means for moving the reaction container, and the movement Cleaning means for cleaning the reaction container moved by the means and stopped at the cleaning position, storage means for storing a container number for identifying the reaction container moved by the moving means and stopped at the positioning position, and the cleaning means Operation means capable of input for executing the washing operation of the reaction vessel by the operation means, and the moving means is identified by the latest container number stored in the storage means according to the input from the operation means The reaction container to be moved is moved to the positioning position before cleaning by the cleaning means is started.

The block diagram which shows the structure of the automatic analyzer which concerns on embodiment. The perspective view which shows the structure of the analysis part which concerns on embodiment. The figure which shows an example of the movement of each reaction container which concerns on embodiment. The figure which shows the stop position where each reaction container which concerns on embodiment stops. The figure which shows an example of a structure of the reaction container washing | cleaning part which concerns on embodiment. The flowchart which shows operation | movement of the automatic analyzer which concerns on embodiment. The figure which shows an example of the screen of the container number of the reaction container stopped at each stop position displayed on the display part which concerns on embodiment.

  Hereinafter, embodiments will be described with reference to the drawings.

  FIG. 1 is a block diagram illustrating a configuration of an automatic analyzer according to the embodiment. This automatic analyzer 100 includes an analysis unit 24 that measures a standard sample and a test sample, an analysis control unit 25 that drives and controls each analysis unit related to the measurement of the analysis unit 24, and the analysis unit 24 that uses the standard sample and the test sample. A data processing unit 30 for generating calibration data and analysis data for each inspection item based on standard data and test data generated by measuring a test sample, calibration data and analysis data generated by the data processing unit 30, and the like , An input for setting analysis parameters for each inspection item, an input for starting maintenance for causing the analysis unit 24 to perform a cleaning operation for cleaning each analysis unit, An operation unit 50 for inputting measurement start for executing a measurement operation of the test sample, and a system control unit 51 that controls the analysis control unit 25, the data processing unit 30, and the output unit 40 in an integrated manner. It is equipped with a.

  FIG. 2 is a perspective view showing the configuration of the analysis unit 24. The analysis unit 24 includes a sample container 17 for storing each sample such as a standard sample and a test sample, a sample disk 5 for holding the sample container 17, and a plurality (m pieces) arranged at equal intervals on the circumference. In addition, a reaction disk 4 that rotatably holds the reaction container 3 identified by the container number, and a dispenser that sucks each sample in the sample container 17 held on the sample disk 5 and discharges it into the reaction container 3. The sample dispensing probe 16 that performs the above operation every cycle and the sample dispensing arm 10 that supports the sample dispensing probe 16 so as to be rotatable and vertically movable are provided.

  In addition, the reagent container 6 that stores the first reagent or the two reagent system of the first reagent that reacts with the component of the test item included in each sample, the reagent container 1 that stores the reagent container 6, and the reagent container 1 are stored. And a reagent rack 1a for rotatably holding the reagent container 6. In addition, a first reagent dispensing probe 14 that performs dispensing for each cycle by sucking the first reagent in the reagent container 6 held in the reagent rack 1a and discharging the reagent into the reaction container 3 from which each sample is discharged; And a first reagent dispensing arm 8 that supports the first reagent dispensing probe 14 so as to be rotatable and vertically movable. In addition, a first stirrer 18 that stirs the mixed solution of each sample and the first reagent discharged into the reaction container 3 for each cycle, and a first stirrer 18 that holds the first stirrer 18 so as to be rotatable and vertically movable. And a stirring arm 19.

  In addition, a reagent container 7 that houses a second reagent that forms a pair with the first reagent of the two-reagent system, a reagent container 2 that stores the reagent container 7, and a reagent container 7 that is stored in the reagent container 2 can be rotated. And a reagent rack 2a for holding. Further, the second reagent dispensing probe 15 that performs dispensing for every cycle by sucking the second reagent in the reagent container 7 held in the reagent rack 2a and discharging the second reagent into the reaction container 3 from which the first reagent has been discharged. And a second reagent dispensing arm 9 that supports the second reagent dispensing probe 15 so as to be rotatable and vertically movable. In addition, the second stirrer 20 that stirs the mixed solution of each sample, the first reagent, and the second reagent discharged into the reaction vessel 3 every cycle, and the second stirrer 20 can be rotated and moved up and down. And a second agitation arm 21 that is held in the chamber.

  Moreover, the photometry part 13 which measures the liquid mixture in the reaction container 3 and the reaction container washing | cleaning part 12 which wash | cleans the inside of the reaction container 3 after measuring by the photometry part 13 are provided. And the photometry part 13 irradiates light to the liquid mixture containing the standard sample and test sample in the reaction container 3 which rotates, and detects the light which permeate | transmitted the liquid mixture. Then, standard data and test data are generated based on the detected light, and the generated standard data and test data are output to the data processing unit 30.

  The analysis control unit 25 stores a container number for identifying the mechanism unit 26 having a mechanism for driving each analysis unit of the analysis unit 24 and the reaction container 3 stopped at a preset positioning position of the analysis unit 24. And a mechanism control unit 28 that controls each mechanism of the mechanism unit 26 and causes the analysis unit 24 to perform a maintenance operation and a measurement operation.

  The mechanism unit 26 includes a mechanism for rotating and driving the disk sampler 5, the reagent rack 1a, and the reagent rack 2a of the analysis unit 24 for each cycle. In addition, a mechanism for rotating the reaction disk 4 every cycle is provided. In addition, a mechanism for rotating and vertically driving the sample dispensing arm 10, the first reagent dispensing arm 8, the second reagent dispensing arm 9, the first stirring arm 19, and the second stirring arm 21 in each cycle is provided. I have. Moreover, the reaction container washing | cleaning part 12 is equipped with the mechanism which carries out washing | cleaning drive for every cycle.

  The auxiliary storage unit 27 includes, for example, a non-volatile storage medium, and is moved by the rotation of the reaction disk 4 in the analysis unit 24 according to the maintenance start or measurement start input from the operation unit 50 and stopped at the positioning position. Save the 3 container number.

  The mechanism control unit 28 calculates the stop position of each reaction vessel 3 based on information on a rotation angle from, for example, a rotary encoder attached to a motor that rotationally drives the reaction disk 4 of the mechanism unit 26. Then, the container number of the reaction container 3 stopped at the positioning position by the maintenance operation or the measurement operation based on the maintenance start or measurement start input from the operation unit 50 is stored in the auxiliary storage unit 27.

  Further, the latest container number stored in the auxiliary storage unit 27 is read before the movement of the reaction container 3 is started in response to the maintenance start or measurement start input from the operation unit 50. When the read container number is a preset container number (fixed number), all the reaction containers 3 have been cleaned in the previous maintenance operation or measurement operation, and are set in a normal position (end position) determined in advance. Judge that it has stopped at. Next, after moving all analysis units including each reaction vessel 3 to the home position, maintenance operation and measurement operation are started, and all analysis units cleaned by the end of maintenance operation and measurement operation are returned to normal positions (end Stop).

  If the read container number is a number other than the fixed number, it is determined that each reaction container 3 is stopped at an abnormal position other than the end position. Next, the reaction disk 4 is rotated before the reaction container cleaning unit 12 starts cleaning, and the reaction container 3 with the read container number is stopped at the positioning position. Next, after moving the analysis units other than the reaction containers 3 to the home position, the maintenance operation and the measurement operation are started, and all the analysis units cleaned by the end of the maintenance operation and the measurement operation are stopped at the end position.

  In the maintenance operation of the analysis unit 24, maintenance cleaning solutions such as an alkaline cleaning solution and an acidic cleaning solution for cleaning contained in the reagent containers 6 and 7 held in the reagent racks 1a and 2a are distributed to each reaction container 3. Noted. In the reaction container 3 into which the maintenance cleaning liquid is dispensed, the maintenance cleaning liquid is washed off by the reaction container cleaning unit 12. Further, in the measurement operation, in the reaction container 3 into which the sample and the reagent are dispensed, the liquid mixture that is no longer needed by the reaction container cleaning unit 12 is washed away.

  Therefore, during the maintenance operation or the measurement operation, the interruption of the power supplied to the automatic analyzer 100 due to a power failure or the like, or the emergency stop due to the occurrence of a hardware error or the like in the analysis unit 24 or the analysis control unit 25 If there is an abrupt stop such as a forced stop by an input from the operation unit 50, a reaction vessel 3 in which the maintenance cleaning liquid remains or a reaction vessel 3 in which a sample or a mixed solution remains is generated. It stops at the position of, i.e. an abnormal position.

  A data processing unit 30 shown in FIG. 1 includes a calculation unit 31 that generates calibration data and analysis data of each inspection item from standard data and test data output from the photometry unit 13 of the analysis unit 24, and a calculation unit 31. And a data storage unit 32 for storing calibration data and analysis data of each generated inspection item. And the calculating part 31 produces | generates calibration data based on the standard data of each test | inspection item produced | generated by the analysis part 24. FIG. Further, analysis data represented by activity values, concentration values, and the like is generated from the test data generated by the analysis unit 24 based on the calibration data of the test items. The generated calibration data and analysis data are stored in the data storage unit 32 and output to the output unit 40.

  The output unit 40 includes a printing unit 41 that prints out calibration data, analysis data, and the like output from the data processing unit 30 and a display unit 42 that performs display output. The printing unit 41 includes a printer and prints and outputs calibration data, analysis data, and the like output from the data processing unit 30 on printer paper according to a preset format. The display unit 42 includes a monitor such as a CRT or a liquid crystal panel, displays an analysis parameter setting screen for setting an analysis parameter of each inspection item, calibration data output from the data processing unit 30, analysis data, and the like. Is displayed.

  The operation unit 50 includes input devices such as a keyboard, a mouse, a button, and a touch key panel, and inputs for setting analysis parameters for each test item, inputs for selecting a test item to be analyzed for each test sample, Input of maintenance start for executing a maintenance operation for cleaning each analysis unit of the analysis unit 24, input of measurement start for causing the analysis unit 24 to perform a measurement operation of a standard sample or a test sample, etc. Make various inputs.

  The system control unit 51 includes a CPU and a storage circuit, and various input information such as command signals input from the operation unit 50, analysis parameters of each test item, subject information, and test items selected for each test sample. Save. Based on the input information, the analysis control unit 25, the data processing unit 30, and the output unit 40 are controlled.

  Next, an example of the configuration and cleaning operation of the reaction vessel cleaning unit 12 of the analysis unit 24 will be described with reference to FIGS. FIG. 3 is a diagram illustrating an example of the movement of each reaction vessel 3. FIG. 4 is a diagram showing a stop position where each reaction vessel 3 stops. FIG. 5 is a diagram illustrating an example of the configuration of the reaction container cleaning unit 12.

  In FIG. 3, each of the m reaction vessels 3 in the analysis unit 24 is rotated in the direction opposite to the R1 direction, for example, by the reaction disk 4 rotating at an angle θ in the direction of the arrow R1 every cycle. Move to position. Each reaction vessel 3 is properly stopped at m places including the washing positions W (first to fifth washing positions W1 to W5) where the reaction vessel washing unit 12 performs washing by rotating the reaction disk 4 m times. Stop at position.

  Then, when the measurement start is input from the operation unit 50, as shown in FIG. 4, the measurement starts after each analysis unit moves to the home position. The reaction vessel 3 stopped at the first cleaning position W1 of the cleaning position W in the first cycle of the measurement start is stopped at the second cleaning position W2 in the second cycle and stopped at the third cleaning position W3 in the third cycle. Further, it stops at the fourth cleaning position W4 in the fourth cycle, and stops at the fifth cleaning position W5 in the fifth cycle. Moreover, it stops at the sample discharge position Pa where the sample can be dispensed by the sample dispensing probe 16 in the a-th cycle (m> a> 5).

  Dispensing by the sample dispensing probe 16 is started in the a cycle, and the sample is discharged into the reaction vessel 3 stopped at the first cleaning position W1 in the first cycle. The reaction container 3 from which the sample has been discharged stops at the first reagent discharge position Pb where the first reagent is dispensed by the first reagent dispensing probe 14 in the b-th cycle (m> b> a). Moreover, it stops at the 1st stirring position Pc in which stirring is performed by the 1st stirring element 18 in c cycle (m> c> b), and 2nd reagent dispensing probe 15 is carried out in d cycle (m> d> c). Stops at the second reagent discharge position Pd where the second reagent is dispensed. Moreover, it stops at the 2nd stirring position Pe where stirring is performed by the 2nd stirring element 20 in e cycle (m> e> d). In addition, when washing is performed again at the first to fifth washing positions W1 to W5 in the (m + 1) to (m + 5) cycles, the reaction vessel 3 stopped at the first washing position W1 in the first cycle. The first measurement is completed. When used for the second measurement, the same operation as in the 6th to (m + 5) cycles is repeated.

  FIG. 5 is a diagram showing an example of the configuration of the reaction container cleaning unit 12. The reaction container cleaning unit 12 includes a cleaning pump unit 55 that supplies each of the first cleaning liquid, the second cleaning liquid, and the cleaning water for cleaning the reaction container 3 during maintenance or measurement. In addition, the cleaning liquid for maintenance in the reaction container 3 dispensed at the time of maintenance and the mixed liquid in the reaction container 3 dispensed at the time of measurement, and the cleaning liquid supplied from the washing pump unit 55 into the reaction container 3 are sucked. And a cleaning nozzle portion 70 held by the mechanism portion 26 so as to be movable up and down for discharging each of the discharged cleaning liquids.

  The cleaning pump unit 55 sucks from the cleaning nozzle unit 70 and a first detergent bottle 56 that stores a first cleaning liquid such as an alkaline cleaning liquid, a second detergent bottle 57 that stores a second cleaning liquid such as an acidic cleaning liquid, and the like. The first drainage tank 58 for storing the maintenance cleaning liquid and the mixed liquid and the second drainage tank 59 for storing the cleaning liquid sucked from the cleaning nozzle unit 70 are provided.

  In addition, the cleaning pump unit 55 sucks the first cleaning liquid from the first detergent bottle 56 and sucks the second cleaning liquid from the first supply pump 60 and the second detergent bottle 57 that supply the cleaning nozzle unit 70 with the first cleaning liquid. The second supply pump 61 that supplies the cleaning nozzle 70 to the cleaning nozzle 70 and the cleaning nozzle for sucking cleaning water such as pure water for washing away the second cleaning liquid remaining in the reaction vessel 3 from the pure water device 110. And a third supply pump 62 that supplies the unit 70.

  Further, the cleaning pump unit 55 includes a first drain pump 63 that causes the cleaning nozzle unit 70 to suck the mixed liquid, and the first to third supply pumps 60 and 61 that discharge the cleaning liquid discharged into the reaction vessel 3. , 62, a second drain pump 64 that causes the cleaning nozzle unit 70 to suck in a suction amount that is larger than the supply amount that is supplied, and a drying pump 65 that causes the cleaning nozzle unit 70 to suck the cleaning water remaining in the reaction vessel 3. It has.

  The cleaning nozzle unit 70 includes a first cleaning nozzle 71 that sucks the maintenance cleaning liquid and the residual liquid of the mixed liquid that are no longer necessary in the reaction vessel 3 stopped at the first cleaning position W1. In addition, the discharge of the first cleaning liquid for washing off the residual liquid adhering to the inner surface of the reaction vessel 3 which stops at the second cleaning position W2 after the residual liquid is sucked at the first cleaning position W1, and the residual liquid after the discharge A second cleaning nozzle 72 for sucking a first cleaning liquid containing In addition, the second cleaning liquid is discharged for further cleaning the inner surface of the reaction vessel 3 that has been cleaned at the second cleaning position W2 and then stopped at the third cleaning position W3, and the discharged residual liquid and the first cleaning liquid are included. And a third cleaning nozzle 73 for sucking the second cleaning liquid.

  In addition, the cleaning nozzle unit 70 discharges cleaning water for cleaning off the second cleaning liquid adhering to the inner surface of the reaction vessel 3 that has been cleaned at the third cleaning position W3 and then stopped at the fourth cleaning position W4, and the discharged first nozzle A fourth cleaning nozzle 74 is provided for sucking cleaning water containing the second cleaning liquid. Further, a fifth cleaning nozzle 75 is provided for sucking and drying the cleaning water remaining in the reaction vessel 3 stopped at the fifth cleaning position W5 after being cleaned at the fourth cleaning position W4. Further, a support body 76 is provided that is held by the mechanism unit 26 that supports the first to fifth cleaning nozzles 71 to 75 so as to be vertically movable.

  Here, operation | movement of 1 cycle of the reaction container washing | cleaning part 12 is demonstrated. After the cleaning nozzle 70 is stopped at the upper stop position above each reaction container 3 at the cleaning position W by driving the mechanism section 26, each reaction container 3 is moved by the rotation of the reaction disk 4 and stopped at each stop position. . After each reaction vessel 3 is stopped, the cleaning nozzle portion 70 is moved downward by driving the mechanism portion 26, and the lower end portions of the first to fifth nozzles 71 to 75 are moved into the respective reaction vessels 3 at the washing position W. Stop at the position where you entered. Next, the inside of the reaction vessel 3 is cleaned by the suction operation and the discharge operation of each pump of the cleaning pump unit 55. After the suction operation and the discharge operation of each pump are stopped, the cleaning nozzle unit 70 moves to the upper side of each reaction vessel 3. This series of operations is repeated every cycle.

Hereinafter, an example of the operation of the automatic analyzer 100 will be described with reference to FIGS. 1 to 7.
FIG. 6 is a flowchart showing the operation of the automatic analyzer 100. The auxiliary storage unit 27 of the analysis control unit 25 stores the container number of the reaction container 3 stopped at the positioning position by the previous measurement operation, for example. For example, when an input for starting measurement of a test sample is performed from the operation unit 50, the automatic analyzer 100 starts operation (step S1).

  Based on the input information input from the operation unit 50, the system control unit 51 instructs the analysis control unit 25, the data processing unit 30, and the output unit 40 to perform an analysis operation. The mechanism control unit 28 of the analysis control unit 25 reads the latest container number stored in the auxiliary storage unit 27 before starting the operation of each analysis unit of the analysis unit 24 (step S2).

  If the read container number is a number other than the fixed number (No in step S3), it is determined that each reaction container 3 is stopped at an abnormal position other than the end position, and the reaction container cleaning unit 12 is cleaned. Before starting the operation, the reaction disk 4 is rotated, and the reaction container 3 with the read container number is stopped at the positioning position (step S4).

  If the read container number is a fixed number (Yes in step S3), it is determined that each reaction container 3 is stopped at a normal position, and all analysis units including each reaction container 3 are set at the home position. Stop (step S5).

  As described above, when it is determined that each reaction container 3 is stopped at an abnormal position, the reaction container 3 of the read container number is stopped at the positioning position before the cleaning operation of the reaction container cleaning unit 12 is started. Thus, each reaction vessel 3 can be stopped at a normal stop position stopped immediately before a sudden stop occurs.

  After step S4 or step S5, the mechanism control unit 28 sets the sample discharge position Pa and the first reagent discharge position Pb when the reaction container 3 with the read container number is stopped at the positioning position or stopped at the home position. The container number of the reaction container 3 that stops at each stop position of the first stirring position Pc, the second reagent discharge position Pd, the second stirring position Pe, and the washing position W is output to the system control unit 51. The system control unit 51 displays the container number of the reaction vessel 3 that stops at each stop position on the display unit 42 of the output unit 40 (step S6).

  FIG. 7 is a diagram showing an example of a container number screen of the reaction container 3 that stops at each stop position displayed on the display unit 42. This screen 43 includes a “measurement start date and time” field for displaying the time when the measurement start input from the operation unit 50 is performed, and each stop position when the measurement is started according to the measurement start input. And a column of “container number at the start of measurement” for displaying the container number of the reaction container 3 stopped at the above.

  In the column “Measurement start date and time”, for example, “January 10, 2011 10:00:00”, which is the time when measurement start is input from the operation unit 50 on January 10, 2011, “2011/01/10 13:30:30” is displayed.

  The column of “container number at the start of measurement” is stopped at the column of “sample discharge position” for displaying the container number of the reaction vessel 3 stopped at the sample stop position Pa, and at the first reagent discharge position Pb. Consists of a "first reagent discharge position" field for displaying the container number of the reaction container 3 and a "first stirring position" field for displaying the container number of the reaction container 3 stopped at the first stirring position Pc. Is done. Further, the column of “second reagent discharge position” for displaying the container number of the reaction container 3 stopped at the second reagent discharge position Pd, and the container number of the reaction container 3 stopped at the second stirring position Pe are displayed. A “second stirring position” field to be displayed and a “washing position” field to display the container number of the reaction vessel 3 stopped at the washing position W are configured.

  In each column of the “container number at the start of measurement” column, “January 10, 2011 10:00:00” to “January 10 2011” displayed in the “Measurement start date and time” column. The vessel number of the reaction vessel 3 stopped at each stop position is displayed when the measurement is started in response to an input of measurement start at “13:30:30”.

  After step S6 in FIG. 6, the mechanism control unit 28 controls the mechanism unit 26 to start measurement. Then, each analysis unit that has been measured without a sudden stop is stopped at the end position (step S7).

  As described above, when it is determined that each reaction container 3 is stopped at an abnormal position, the reaction container cleaning unit 12 is stopped after each reaction container 3 is stopped at a normal stop position stopped immediately before the sudden stop occurs. By starting the cleaning operation, the maintenance cleaning liquid stopped at an arbitrary position due to a sudden stop in the middle of the previous operation, or the reaction vessel 3 in which the sample or the mixed liquid remains is properly treated immediately before the sudden stop occurs. Cleaning of each reaction vessel 3 can be continued from the position returned to the stop position.

  As a result, the second to fifth washings are performed before the maintenance washing liquid, or the reaction container 3 in which the sample or the mixed liquid remains, stops at the first washing position W1 and the first washing nozzle 71 sucks the remaining liquid. It can be stopped at the positions W2 to W5 and the fourth and fifth cleaning nozzles 74 and 75 can be prevented from entering the reaction vessel 3 and being contaminated with the maintenance cleaning liquid. Further, it is possible to prevent the second to fifth cleaning nozzles 72 to 75 from entering the reaction vessel 3 and being contaminated with the sample or the mixed solution.

  In addition, since it is possible to avoid re-cleaning the cleaned reaction vessel 3 before sudden stoppage occurs, waste of the first and second cleaning liquids and cleaning water can be prevented.

  After the measurement in the analysis unit 24 is completed and the analysis data is output from the output unit 40, the system control unit 51 instructs the analysis control unit 25, the data processing unit 30, and the output unit 40 to stop the analysis operation. The automatic analyzer 100 ends the operation (step S8).

  According to the embodiment described above, the auxiliary storage unit 27 for storing the container number of the reaction container 3 stopped at the positioning position is provided, and maintenance start or the maintenance operation with the execution of the cleaning operation of the reaction container cleaning unit 12 from the operation unit 50 is performed. The latest container number stored in the auxiliary storage unit 27 is read in response to the measurement start input. When the read container number is a number other than the fixed number, the reaction container 3 with the read container number is stopped at the positioning position before the cleaning operation of the reaction container cleaning unit 12 is started. Each reaction vessel 3 can be stopped at a normal stop position stopped immediately before the occurrence of the occurrence of the reaction.

  Then, after the reaction containers 3 are stopped at the regular stop positions, the cleaning operation of the reaction container cleaning unit 12 is started, so that the maintenance cleaning liquid stopped at an arbitrary position due to the previous rapid stop, or the sample or the mixture Cleaning of each reaction container 3 can be continued from the position where the reaction container 3 in which the liquid remains is returned to the normal stop position immediately before the sudden stop.

  As a result, the second to fifth cleaning liquids are maintained before the maintenance cleaning liquid or the reaction vessel 3 in which the sample or the mixed liquid remains is stopped at the first cleaning position W1 and the first cleaning nozzle 71 sucks the residual liquid. It can be stopped at the positions W2 to W5 and the fourth and fifth cleaning nozzles 74 and 75 can be prevented from entering the reaction vessel 3 and being contaminated with the maintenance cleaning liquid. Further, it is possible to prevent the second to fifth cleaning nozzles 72 to 75 from entering the reaction vessel 3 and being contaminated with the sample or the mixed solution. In addition, since it is possible to avoid re-cleaning the cleaned reaction vessel 3 before sudden stoppage occurs, waste of the first and second cleaning liquids and cleaning water can be prevented.

  As described above, the reaction vessel cleaning unit 12 can be prevented from being enlarged without being contaminated with the residual liquid.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

3 Reaction vessel 4 Reaction disk 12 Reaction vessel washing unit 25 Analysis control unit 26 Mechanism unit 27 Auxiliary storage unit 28 Mechanism control unit

Claims (3)

In an automatic analyzer that dispenses samples and reagents into reaction vessels and measures the mixture,
Moving means for moving the reaction vessel;
Washing means for washing the reaction vessel moved by the moving means and stopped at the washing position;
Storage means for storing a container number for identifying the reaction container moved by the moving means and stopped at the positioning position;
An operation means capable of input for causing the washing means to perform the washing operation of the reaction vessel,
In response to an input from the operation means, the moving means moves the reaction container identified by the latest container number stored in the storage means to the positioning position before the cleaning means starts cleaning. The automatic analyzer characterized by doing.   The moving means moves the reaction container identified by the latest container number to the positioning position when the latest container number is a number other than a fixed number, and the latest container number is the fixed number. 2. The automatic analyzer according to claim 1, wherein in some cases, the reaction vessel is moved to a home position.   3. The automatic analyzer according to claim 1, further comprising display means for displaying a container number for identifying the reaction container stopped at the positioning position or the home position.

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