JP2012533605A - 神経セロイドリポフスチン症の治療における使用のための１ｈ−キナゾリン−２，４−ジオン - Google Patents
神経セロイドリポフスチン症の治療における使用のための１ｈ−キナゾリン−２，４−ジオン Download PDFInfo
- Publication number
- JP2012533605A JP2012533605A JP2012521055A JP2012521055A JP2012533605A JP 2012533605 A JP2012533605 A JP 2012533605A JP 2012521055 A JP2012521055 A JP 2012521055A JP 2012521055 A JP2012521055 A JP 2012521055A JP 2012533605 A JP2012533605 A JP 2012533605A
- Authority
- JP
- Japan
- Prior art keywords
- dioxo
- dihydro
- quinazolin
- methanesulfonamide
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22794009P | 2009-07-23 | 2009-07-23 | |
| US61/227,940 | 2009-07-23 | ||
| PCT/EP2010/060733 WO2011009951A1 (en) | 2009-07-23 | 2010-07-23 | 1h-quinazoline-2, 4 -diones for use in the treatment of neuronal ceroid lipofuscinosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2012533605A true JP2012533605A (ja) | 2012-12-27 |
Family
ID=42671655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521055A Pending JP2012533605A (ja) | 2009-07-23 | 2010-07-23 | 神経セロイドリポフスチン症の治療における使用のための１ｈ−キナゾリン−２，４−ジオン |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20120122903A1 (enExample) |
| EP (1) | EP2456442A1 (enExample) |
| JP (1) | JP2012533605A (enExample) |
| KR (1) | KR20120052341A (enExample) |
| CN (1) | CN102470137A (enExample) |
| AU (1) | AU2010274921B2 (enExample) |
| BR (1) | BR112012001258A2 (enExample) |
| CA (1) | CA2768333A1 (enExample) |
| IN (1) | IN2012DN00235A (enExample) |
| MX (1) | MX2012000956A (enExample) |
| RU (1) | RU2012106426A (enExample) |
| WO (1) | WO2011009951A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5976011B2 (ja) * | 2011-04-05 | 2016-08-23 | 武田薬品工業株式会社 | スルホンアミド誘導体およびその用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019346A1 (en) * | 1994-01-14 | 1995-07-20 | Sandoz Ltd. | Quinazoline-2,4-diones |
| WO2006108591A1 (en) * | 2005-04-11 | 2006-10-19 | Novartis Ag | 1h-quinaz0line-2,4-diones and their use as ampa-receptor ligands |
| JP2008508216A (ja) * | 2004-07-27 | 2008-03-21 | ノバルティス アクチエンゲゼルシャフト | キナゾリン誘導体 |
-
2010
- 2010-07-23 CN CN2010800334750A patent/CN102470137A/zh active Pending
- 2010-07-23 RU RU2012106426/04A patent/RU2012106426A/ru not_active Application Discontinuation
- 2010-07-23 MX MX2012000956A patent/MX2012000956A/es not_active Application Discontinuation
- 2010-07-23 IN IN235DEN2012 patent/IN2012DN00235A/en unknown
- 2010-07-23 BR BR112012001258A patent/BR112012001258A2/pt not_active IP Right Cessation
- 2010-07-23 US US13/384,280 patent/US20120122903A1/en not_active Abandoned
- 2010-07-23 AU AU2010274921A patent/AU2010274921B2/en not_active Expired - Fee Related
- 2010-07-23 WO PCT/EP2010/060733 patent/WO2011009951A1/en not_active Ceased
- 2010-07-23 KR KR1020127004575A patent/KR20120052341A/ko not_active Withdrawn
- 2010-07-23 EP EP10734746A patent/EP2456442A1/en not_active Withdrawn
- 2010-07-23 JP JP2012521055A patent/JP2012533605A/ja active Pending
- 2010-07-23 CA CA2768333A patent/CA2768333A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995019346A1 (en) * | 1994-01-14 | 1995-07-20 | Sandoz Ltd. | Quinazoline-2,4-diones |
| JP2008508216A (ja) * | 2004-07-27 | 2008-03-21 | ノバルティス アクチエンゲゼルシャフト | キナゾリン誘導体 |
| WO2006108591A1 (en) * | 2005-04-11 | 2006-10-19 | Novartis Ag | 1h-quinaz0line-2,4-diones and their use as ampa-receptor ligands |
Non-Patent Citations (2)
| Title |
|---|
| JPN5012014296; ＫＯＶＡＣＳ Ａ Ｄ: 'ＡＴＴＥＮＵＡＴＩＯＮ ＯＦ ＡＭＰＡ ＲＥＣＥＰＴＯＲ ＡＣＴＩＶＩＴＹ ＩＭＰＲＯＶＥＳ ＭＯＴＯＲ ＳＫＩＬＬＳ ＩＮ Ａ ＭＯＵＳＥ ＭＯＤＥＬ 以下備考' ＥＸＰＥＲＩＭＥＮＴＡＬ ＮＥＵＲＯＬＯＧＹ Ｖ２０９ Ｎ１, 20080101, Ｐ２８８-２９１, ＡＣＡＤＥＭＩＣ ＰＲＥＳＳ * |
| JPN5012014297; ＥＬＧＥＲ ＢＥＲＮＤ: 'ＯＰＴＩＭＩＺＥＤ ＳＹＮＴＨＥＳＩＳ ＯＦ ＡＭＰＡ ＲＥＣＥＰＴＯＲ ＡＮＴＡＧＯＮＩＳＴ ＺＫ １８７６３８ ＡＮＤ ＮＥＵＲＯＢＥＨＡＶＩＯＲＡＬ ＡＣＴＩＶＩＴＹ 以下備考' ＣＨＥＭＭＥＤＣＨＥＭ Ｖ１ Ｎ１０, 200610, Ｐ１１４２-１１４８ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102470137A (zh) | 2012-05-23 |
| KR20120052341A (ko) | 2012-05-23 |
| AU2010274921A1 (en) | 2012-02-02 |
| BR112012001258A2 (pt) | 2016-02-10 |
| CA2768333A1 (en) | 2011-01-27 |
| EP2456442A1 (en) | 2012-05-30 |
| MX2012000956A (es) | 2012-02-28 |
| AU2010274921B2 (en) | 2014-08-14 |
| IN2012DN00235A (enExample) | 2015-05-01 |
| RU2012106426A (ru) | 2013-08-27 |
| US20120122903A1 (en) | 2012-05-17 |
| WO2011009951A1 (en) | 2011-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20130723 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20141009 |
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| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20141014 |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20150519 |