BR112012001258A2 - 1h-quinazolina-2,4-dionas para uso no tratamento da lipofuscinose ceroide neuronal - Google Patents

1h-quinazolina-2,4-dionas para uso no tratamento da lipofuscinose ceroide neuronal

Info

Publication number
BR112012001258A2
BR112012001258A2 BR112012001258A BR112012001258A BR112012001258A2 BR 112012001258 A2 BR112012001258 A2 BR 112012001258A2 BR 112012001258 A BR112012001258 A BR 112012001258A BR 112012001258 A BR112012001258 A BR 112012001258A BR 112012001258 A2 BR112012001258 A2 BR 112012001258A2
Authority
BR
Brazil
Prior art keywords
diones
quinazoline
treatment
neuronal ceroid
ceroid lipofuscinosis
Prior art date
Application number
BR112012001258A
Other languages
English (en)
Portuguese (pt)
Inventor
Hans O Kalkman
Henri Mattes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR112012001258A2 publication Critical patent/BR112012001258A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112012001258A 2009-07-23 2010-07-23 1h-quinazolina-2,4-dionas para uso no tratamento da lipofuscinose ceroide neuronal BR112012001258A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22794009P 2009-07-23 2009-07-23
PCT/EP2010/060733 WO2011009951A1 (en) 2009-07-23 2010-07-23 1h-quinazoline-2, 4 -diones for use in the treatment of neuronal ceroid lipofuscinosis

Publications (1)

Publication Number Publication Date
BR112012001258A2 true BR112012001258A2 (pt) 2016-02-10

Family

ID=42671655

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012001258A BR112012001258A2 (pt) 2009-07-23 2010-07-23 1h-quinazolina-2,4-dionas para uso no tratamento da lipofuscinose ceroide neuronal

Country Status (12)

Country Link
US (1) US20120122903A1 (enExample)
EP (1) EP2456442A1 (enExample)
JP (1) JP2012533605A (enExample)
KR (1) KR20120052341A (enExample)
CN (1) CN102470137A (enExample)
AU (1) AU2010274921B2 (enExample)
BR (1) BR112012001258A2 (enExample)
CA (1) CA2768333A1 (enExample)
IN (1) IN2012DN00235A (enExample)
MX (1) MX2012000956A (enExample)
RU (1) RU2012106426A (enExample)
WO (1) WO2011009951A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5976011B2 (ja) * 2011-04-05 2016-08-23 武田薬品工業株式会社 スルホンアミド誘導体およびその用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9400680D0 (en) * 1994-01-14 1994-03-09 Sandoz Ltd Improvements in or relating to organic compounds
GB0416730D0 (en) * 2004-07-27 2004-09-01 Novartis Ag Organic compounds
GB0507298D0 (en) * 2005-04-11 2005-05-18 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
IN2012DN00235A (enExample) 2015-05-01
EP2456442A1 (en) 2012-05-30
RU2012106426A (ru) 2013-08-27
JP2012533605A (ja) 2012-12-27
CN102470137A (zh) 2012-05-23
WO2011009951A1 (en) 2011-01-27
KR20120052341A (ko) 2012-05-23
AU2010274921A1 (en) 2012-02-02
US20120122903A1 (en) 2012-05-17
AU2010274921B2 (en) 2014-08-14
CA2768333A1 (en) 2011-01-27
MX2012000956A (es) 2012-02-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]