PT2323642E - Utilização de edta+trometamina ou de fotoiativadores, associados a riboflavina para reticulação da córnea no tratamento de ceratocone ou de outros distúrbios ectásicos da córnea - Google Patents
Utilização de edta+trometamina ou de fotoiativadores, associados a riboflavina para reticulação da córnea no tratamento de ceratocone ou de outros distúrbios ectásicos da córnea Download PDFInfo
- Publication number
- PT2323642E PT2323642E PT97484943T PT09748494T PT2323642E PT 2323642 E PT2323642 E PT 2323642E PT 97484943 T PT97484943 T PT 97484943T PT 09748494 T PT09748494 T PT 09748494T PT 2323642 E PT2323642 E PT 2323642E
- Authority
- PT
- Portugal
- Prior art keywords
- corneal
- photoenhancers
- keratoconus
- tromethamine
- riboflavin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM2008A000472A IT1393402B1 (it) | 2008-08-28 | 2008-08-28 | Uso di enhancer eventualmente con riboflavina, nonche' relative composizioni oftalmiche per cross-linking corneale del cheratocono o di altre patologie ectasiche corneali |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2323642E true PT2323642E (pt) | 2014-05-15 |
Family
ID=40679354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97484943T PT2323642E (pt) | 2008-08-28 | 2009-08-27 | Utilização de edta+trometamina ou de fotoiativadores, associados a riboflavina para reticulação da córnea no tratamento de ceratocone ou de outros distúrbios ectásicos da córnea |
Country Status (18)
Country | Link |
---|---|
US (1) | US20110152219A1 (pt) |
EP (1) | EP2323642B1 (pt) |
JP (1) | JP2012500844A (pt) |
KR (1) | KR20110046567A (pt) |
CN (1) | CN102164592B (pt) |
AU (1) | AU2009286285B2 (pt) |
BR (1) | BRPI0910368B8 (pt) |
CL (1) | CL2011000378A1 (pt) |
DK (1) | DK2323642T3 (pt) |
EA (2) | EA022055B1 (pt) |
ES (1) | ES2460578T3 (pt) |
IL (1) | IL211448A (pt) |
IT (1) | IT1393402B1 (pt) |
MX (2) | MX2011002234A (pt) |
PE (1) | PE20110287A1 (pt) |
PL (1) | PL2323642T3 (pt) |
PT (1) | PT2323642E (pt) |
WO (1) | WO2010023705A1 (pt) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009073213A1 (en) | 2007-12-05 | 2009-06-11 | Avedro, Inc. | Eye therapy system |
WO2010039854A1 (en) | 2008-09-30 | 2010-04-08 | Neal Marshall | Eye therapy system |
US9707126B2 (en) | 2009-10-21 | 2017-07-18 | Avedro, Inc. | Systems and methods for corneal cross-linking with pulsed light |
WO2011050164A1 (en) | 2009-10-21 | 2011-04-28 | Avedro, Inc. | Eye therapy |
JP6377906B2 (ja) | 2010-03-19 | 2018-08-22 | アヴェドロ・インコーポレーテッドAvedro,Inc. | 眼治療を適用およびモニターするためのシステム |
US20120289886A1 (en) * | 2010-04-13 | 2012-11-15 | Avedro, Inc. | Controlled application of cross-linking agent |
US20110280763A1 (en) * | 2010-05-17 | 2011-11-17 | Abbott Medical Optics Inc. | Light-activated disinfection system |
IT1400982B1 (it) | 2010-07-05 | 2013-07-05 | Pinelli | Collirio osmotico trans-epiteliale per la cura del cheratocono. |
US9622911B2 (en) | 2010-09-30 | 2017-04-18 | Cxl Ophthalmics, Llc | Ophthalmic treatment device, system, and method of use |
EA022306B1 (ru) | 2011-01-12 | 2015-12-30 | Соофт Италия Спа | Устройство и способ подачи рибофлавина в роговицу путем ионофореза для лечения кератоконуса |
MX2013008042A (es) | 2011-01-12 | 2013-09-16 | Sooft Italia Spa | Suministro a la cornea de agentes de reticulacion mediante iontoforesis, para el tratamiento del queratocono y composiciones oftalmicas relacionadas. |
US9044308B2 (en) | 2011-05-24 | 2015-06-02 | Avedro, Inc. | Systems and methods for reshaping an eye feature |
WO2012167260A2 (en) | 2011-06-02 | 2012-12-06 | Avedro, Inc. | Systems and methods for monitoring time based photo active agent delivery or photo active marker presence |
ITRM20110560A1 (it) * | 2011-10-25 | 2013-04-26 | Sooft Italia Spa | Migliorata composizione di cross-linking per il trattamento del cheratocono mediante iontoforesi |
RU2481809C1 (ru) * | 2011-12-21 | 2013-05-20 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ лечения кератэктазии после лазик |
EP2830637A4 (en) | 2012-03-29 | 2016-03-16 | Cxl Ophthalmics Llc | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES RELATED TO OXIDATIVE STRESS |
WO2013148896A1 (en) * | 2012-03-29 | 2013-10-03 | Cxl Ophthalmics, Llc | Ocular treatment solutions, delivery devices and delivery augmentation methods |
WO2013148895A1 (en) | 2012-03-29 | 2013-10-03 | Cxl Ophthalmics, Llc | Ocular cross-linking system and method for sealing corneal wounds |
RU2487691C1 (ru) * | 2012-04-12 | 2013-07-20 | Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения кератоконуса |
WO2014114359A1 (en) * | 2013-01-28 | 2014-07-31 | Wavelight Gmbh | Apparatus for corneal crosslinking |
EP3858356A3 (en) * | 2013-05-19 | 2021-12-01 | Avedro, Inc. | Systems, methods, and compositions for cross-linking |
WO2014205145A1 (en) | 2013-06-18 | 2014-12-24 | Avedro, Inc. | Systems and methods for determining biomechanical properties of the eye for applying treatment |
US9498114B2 (en) | 2013-06-18 | 2016-11-22 | Avedro, Inc. | Systems and methods for determining biomechanical properties of the eye for applying treatment |
RU2542799C1 (ru) * | 2013-10-29 | 2015-02-27 | Игорь Борисович Медведев | Способ лечения кератоконуса роговицы |
US9931199B2 (en) * | 2014-05-05 | 2018-04-03 | Roberto Gustavo ALBERTAZZI | Methods and apparatus for treating keratoconus |
US10195081B1 (en) | 2014-05-12 | 2019-02-05 | Gholam A. Peyman | Method of prevention of capsular opacification and fibrosis after cataract extraction and/or prevention of fibrosis around a shunt or stent after glaucoma surgery |
US10278920B1 (en) | 2014-05-12 | 2019-05-07 | Gholam A. Peyman | Drug delivery implant and a method using the same |
US10314690B1 (en) | 2014-05-12 | 2019-06-11 | Gholam A. Peyman | Method of corneal transplantation or corneal inlay implantation with cross-linking |
US11565023B2 (en) | 2014-05-12 | 2023-01-31 | Gholam A. Peyman | Method of corneal transplantation or corneal inlay implantation with cross-linking |
US11666777B2 (en) | 2014-05-12 | 2023-06-06 | Gholam A. Peyman | Photodynamic therapy technique for preventing damage to the fovea of the eye or another body portion of a patient |
US11648261B2 (en) | 2014-05-12 | 2023-05-16 | Gholam A. Peyman | Method of treating, reducing, or alleviating a medical condition in a patient |
US9427355B1 (en) * | 2014-05-12 | 2016-08-30 | Gholam A. Peyman | Corneal transplantation with a cross-linked cornea |
US10881503B2 (en) | 2014-05-12 | 2021-01-05 | Gholam A. Peyman | Method of corneal transplantation or corneal inlay implantation with cross-linking |
US11045352B2 (en) | 2014-05-12 | 2021-06-29 | Gholam A. Peyman | Methods for treatment of dry eye and other acute or chronic inflammatory processes |
US9744029B1 (en) | 2014-05-12 | 2017-08-29 | Gholam A. Peyman | Method of preventing capsular opacification and fibrosis utilizing an accommodative intraocular lens implant |
US10709546B2 (en) | 2014-05-12 | 2020-07-14 | Gholam A. Peyman | Intracorneal lens implantation with a cross-linked cornea |
US10583221B2 (en) | 2014-05-12 | 2020-03-10 | Gholam A. Peyman | Method of corneal transplantation or corneal inlay implantation with cross-linking |
US9937033B1 (en) | 2014-05-12 | 2018-04-10 | Gholam A. Peyman | Corneal lenslet implantation with a cross-linked cornea |
US11338059B2 (en) | 2014-05-12 | 2022-05-24 | Gholam A. Peyman | Method of corneal and scleral inlay crosslinking and preservation |
US10206569B1 (en) | 2014-05-12 | 2019-02-19 | Gholam A. Peyman | Corneal intraocular pressure sensor and a surgical method using the same |
US10925889B2 (en) | 2014-05-12 | 2021-02-23 | Gholam A. Peyman | Method of treating, reducing, or alleviating a medical condition in a patient |
US11259914B2 (en) | 2014-05-12 | 2022-03-01 | Gholam A. Peyman | Molding or 3-D printing of a synthetic refractive corneal lenslet |
CN107205845B (zh) | 2014-10-27 | 2020-03-31 | 艾维德洛公司 | 用于眼的交联治疗的系统和方法 |
US10114205B2 (en) | 2014-11-13 | 2018-10-30 | Avedro, Inc. | Multipass virtually imaged phased array etalon |
EP3827792A1 (en) | 2015-04-24 | 2021-06-02 | Avedro, Inc. | Systems and methods for photoactivating a photosensitizer applied to an eye |
PT3288588T (pt) | 2015-04-29 | 2018-11-13 | Sooft Italia Spa | Agentes de reticulação melhorados de fibras de colagénio para uso no tratamento da ectasia corneana |
WO2016191342A1 (en) | 2015-05-22 | 2016-12-01 | Avedro, Inc. | Systems and methods for monitoring cross-linking activity for corneal treatments |
CN108025011A (zh) * | 2015-07-21 | 2018-05-11 | 艾维德洛公司 | 用光敏剂治疗眼睛的系统和方法 |
CN105256059B (zh) * | 2015-11-20 | 2019-01-18 | 山东省眼科研究所 | Tuba3d基因在制备圆锥角膜诊断制品中的应用 |
ITUB20160237A1 (it) | 2016-01-26 | 2017-07-26 | Vision Engineering Italy Soc A Responsabilita Limitata | Apparato di controllo del dosaggio di un agente cromoforo in un tessuto corneale e procedimento per dosare un agente cromoforo in un tessuto corneale |
EP3442481B1 (en) | 2016-04-13 | 2023-06-28 | Avedro, Inc. | Systems for delivering drugs to an eye |
US20180236077A1 (en) * | 2017-02-21 | 2018-08-23 | Avedro, Inc. | Formulations for eye treatments |
AU2019231257A1 (en) | 2018-03-05 | 2020-10-15 | Avedro, Inc. | System for eye tracking during eye treatment |
US11766356B2 (en) | 2018-03-08 | 2023-09-26 | Avedro, Inc. | Micro-devices for treatment of an eye |
US12016794B2 (en) | 2018-10-09 | 2024-06-25 | Avedro, Inc. | Photoactivation systems and methods for corneal cross-linking treatments |
US11707518B2 (en) | 2019-04-28 | 2023-07-25 | Gholam A. Peyman | Method of treating, reducing, or alleviating a medical condition in a patient |
WO2021026405A1 (en) | 2019-08-06 | 2021-02-11 | Avedro, Inc. | Photoactivation systems and methods for corneal cross-linking treatments |
CN110314034B (zh) * | 2019-08-08 | 2021-12-03 | 南京市第一医院 | 一种可实现个性治疗的角膜交联装置 |
US11458220B2 (en) | 2020-11-12 | 2022-10-04 | Singletto Inc. | Microbial disinfection for personal protection equipment |
CN115177729B (zh) * | 2022-08-03 | 2023-09-26 | 山东第一医科大学附属眼科研究所(山东省眼科研究所、山东第一医科大学附属青岛眼科医院) | 肾上腺素受体激动剂在制备圆锥角膜交联促渗剂中的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050002867A1 (en) * | 1997-10-01 | 2005-01-06 | Novadel Pharma Inc. | Buccal, polar and non-polar sprays containing propofol |
EP1061873B1 (en) * | 1998-03-09 | 2005-11-02 | Ista Pharmaceuticals, Inc | Use of glyceraldehyde as corneal hardening agents |
US6174524B1 (en) | 1999-03-26 | 2001-01-16 | Alcon Laboratories, Inc. | Gelling ophthalmic compositions containing xanthan gum |
AU2001249984B2 (en) * | 2000-02-11 | 2005-05-26 | The General Hospital Corporation | Photochemical tissue bonding |
JP5583310B2 (ja) * | 2002-12-20 | 2014-09-03 | チャクシュ・リサーチ・インコーポレーテッド | 眼球の症状の予防及び治療のための眼科用製剤 |
ITRM20050443A1 (it) * | 2005-08-12 | 2007-02-13 | Opocrin Spa | Preparati oftalmici a base di polisaccaridi mucoadesivi con capacita' riepitelizzante della cornea. |
US20120203161A1 (en) * | 2009-08-12 | 2012-08-09 | Seros Medical, Llc | Deuterated water and riboflavin solution for extending singlet oxygen lifetimes in treatment of ocular tissue and method of use |
-
2008
- 2008-08-28 IT ITRM2008A000472A patent/IT1393402B1/it active
-
2009
- 2009-08-27 EA EA201100393A patent/EA022055B1/ru not_active IP Right Cessation
- 2009-08-27 WO PCT/IT2009/000392 patent/WO2010023705A1/en active Application Filing
- 2009-08-27 CN CN200980138188.3A patent/CN102164592B/zh active Active
- 2009-08-27 EP EP09748494.3A patent/EP2323642B1/en active Active
- 2009-08-27 MX MX2011002234A patent/MX2011002234A/es active IP Right Grant
- 2009-08-27 AU AU2009286285A patent/AU2009286285B2/en active Active
- 2009-08-27 BR BRPI0910368A patent/BRPI0910368B8/pt active IP Right Grant
- 2009-08-27 PL PL09748494T patent/PL2323642T3/pl unknown
- 2009-08-27 DK DK09748494.3T patent/DK2323642T3/da active
- 2009-08-27 JP JP2011524534A patent/JP2012500844A/ja active Pending
- 2009-08-27 KR KR1020117006855A patent/KR20110046567A/ko not_active Application Discontinuation
- 2009-08-27 ES ES09748494.3T patent/ES2460578T3/es active Active
- 2009-08-27 PE PE2011000192A patent/PE20110287A1/es not_active Application Discontinuation
- 2009-08-27 MX MX2013013707A patent/MX358176B/es unknown
- 2009-08-27 PT PT97484943T patent/PT2323642E/pt unknown
- 2009-08-27 EA EA201300272A patent/EA023607B1/ru not_active IP Right Cessation
-
2011
- 2011-02-22 CL CL2011000378A patent/CL2011000378A1/es unknown
- 2011-02-27 IL IL211448A patent/IL211448A/en active IP Right Grant
- 2011-02-28 US US13/036,492 patent/US20110152219A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EA022055B1 (ru) | 2015-10-30 |
MX358176B (es) | 2018-08-08 |
WO2010023705A1 (en) | 2010-03-04 |
EP2323642B1 (en) | 2014-02-19 |
AU2009286285A1 (en) | 2010-03-04 |
IL211448A (en) | 2016-05-31 |
MX2011002234A (es) | 2011-04-05 |
EP2323642A1 (en) | 2011-05-25 |
PL2323642T3 (pl) | 2014-07-31 |
CN102164592B (zh) | 2015-09-23 |
CL2011000378A1 (es) | 2011-06-10 |
EA023607B1 (ru) | 2016-06-30 |
JP2012500844A (ja) | 2012-01-12 |
ITRM20080472A1 (it) | 2010-02-28 |
CN102164592A (zh) | 2011-08-24 |
EA201100393A1 (ru) | 2011-10-31 |
US20110152219A1 (en) | 2011-06-23 |
AU2009286285B2 (en) | 2015-03-26 |
IL211448A0 (en) | 2011-05-31 |
PE20110287A1 (es) | 2011-05-15 |
IT1393402B1 (it) | 2012-04-20 |
BRPI0910368A2 (pt) | 2015-10-13 |
EA201300272A1 (ru) | 2013-07-30 |
DK2323642T3 (da) | 2014-05-05 |
BRPI0910368B8 (pt) | 2021-05-25 |
ES2460578T3 (es) | 2014-05-13 |
KR20110046567A (ko) | 2011-05-04 |
BRPI0910368B1 (pt) | 2020-01-28 |
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