|
CN104364239B
(zh)
|
2012-06-13 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
二氮杂螺环烷烃和氮杂螺环烷烃
|
|
MX368615B
(es)
*
|
2012-09-25 |
2019-10-09 |
Hoffmann La Roche |
Derivados bicíclicos como inhibidores de la autotaxina (atx) que son inhibidores de la producción de ácido lisofosfatídico (lpa) y el uso de los mismos.
|
|
US9409895B2
(en)
|
2012-12-19 |
2016-08-09 |
Novartis Ag |
Autotaxin inhibitors
|
|
US9630945B2
(en)
|
2012-12-19 |
2017-04-25 |
Novartis Ag |
Autotaxin inhibitors
|
|
AR095079A1
(es)
*
|
2013-03-12 |
2015-09-16 |
Hoffmann La Roche |
Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
|
|
WO2014152725A1
(en)
*
|
2013-03-15 |
2014-09-25 |
Biogen Idec Ma Inc. |
S1p and/or atx modulating agents
|
|
EP3046909A4
(en)
|
2013-09-17 |
2017-03-29 |
Pharmakea, Inc. |
Heterocyclic vinyl autotaxin inhibitor compounds
|
|
US9714240B2
(en)
|
2013-09-17 |
2017-07-25 |
Pharmakea, Inc. |
Vinyl autotaxin inhibitor compounds
|
|
EP3049405A4
(en)
|
2013-09-26 |
2017-03-08 |
Pharmakea Inc. |
Autotaxin inhibitor compounds
|
|
US9926318B2
(en)
|
2013-11-22 |
2018-03-27 |
Pharmakea, Inc. |
Tetracyclic autotaxin inhibitors
|
|
EP3071561B1
(en)
|
2013-11-22 |
2021-03-24 |
Sabre Therapeutics LLC |
Autotaxin inhibitor compounds
|
|
DK3074400T3
(en)
|
2013-11-26 |
2018-01-15 |
Hoffmann La Roche |
Octahydro-cyclobuta [1,2-c; 3,4-c '] dipyrrole derivatives as autotaxin inhibitors
|
|
CA2937616A1
(en)
|
2014-03-26 |
2015-10-01 |
F. Hoffmann-La Roche Ag |
Bicyclic compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
|
|
EA032357B1
(ru)
*
|
2014-03-26 |
2019-05-31 |
Ф. Хоффманн-Ля Рош Аг |
Конденсированные [1,4]диазепиновые соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa)
|
|
CU24442B1
(es)
|
2014-04-04 |
2019-09-04 |
X Rx Inc |
Derivados de n-(1-(espirocíclico)oxo) amida sustituidos como inhibidores de autotaxina
|
|
BR112016024473A2
(pt)
*
|
2014-04-23 |
2018-01-23 |
X Rx Inc |
composto, composição farmacêutica, e, método para tratamento de uma doença e/ou condição
|
|
US9051320B1
(en)
|
2014-08-18 |
2015-06-09 |
Pharmakea, Inc. |
Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor
|
|
GB201501870D0
(en)
|
2015-02-04 |
2015-03-18 |
Cancer Rec Tech Ltd |
Autotaxin inhibitors
|
|
GB201502020D0
(en)
|
2015-02-06 |
2015-03-25 |
Cancer Rec Tech Ltd |
Autotaxin inhibitory compounds
|
|
MA41898A
(fr)
|
2015-04-10 |
2018-02-13 |
Hoffmann La Roche |
Dérivés de quinazolinone bicyclique
|
|
CA2986759C
(en)
|
2015-05-27 |
2025-06-17 |
Sabre Therapeutics Llc |
AUTOTAXIN INHIBITORS AND THEIR USES
|
|
AU2016270373A1
(en)
|
2015-06-05 |
2018-01-04 |
Vertex Pharmaceuticals Incorporated |
Triazoles for the treatment of demyelinating diseases
|
|
GB201510010D0
(en)
|
2015-06-09 |
2015-07-22 |
King S College London |
PDD and BPD compounds
|
|
GB201514928D0
(en)
|
2015-08-21 |
2015-10-07 |
King S College London |
PDD compounds
|
|
US20180339985A1
(en)
|
2015-08-21 |
2018-11-29 |
Femtogenix Limited |
Pdd compounds
|
|
CA2992889A1
(en)
|
2015-09-04 |
2017-03-09 |
F. Hoffmann-La Roche Ag |
Phenoxymethyl derivatives
|
|
AU2016328436B2
(en)
|
2015-09-24 |
2020-05-14 |
F. Hoffmann-La Roche Ag |
New bicyclic compounds as dual ATX/CA inhibitors
|
|
BR112017026682A2
(pt)
|
2015-09-24 |
2018-08-14 |
Hoffmann La Roche |
novos compostos bicíclicos como inibidores de dupla ação de atx/ca
|
|
JP6876685B2
(ja)
|
2015-09-24 |
2021-05-26 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ａｔｘ阻害剤としての二環式化合物
|
|
WO2017050732A1
(en)
|
2015-09-24 |
2017-03-30 |
F. Hoffmann-La Roche Ag |
Bicyclic compounds as atx inhibitors
|
|
WO2018106643A1
(en)
|
2016-12-06 |
2018-06-14 |
Vertex Pharmaceuticals Incorporated |
Heterocyclic azoles for the treatment of demyelinating diseases
|
|
WO2018106641A1
(en)
|
2016-12-06 |
2018-06-14 |
Vertex Pharmaceuticals Incorporated |
Pyrazoles for the treatment of demyelinating diseases
|
|
WO2018106646A1
(en)
|
2016-12-06 |
2018-06-14 |
Vertex Pharmaceuticals Incorporated |
Aminotriazoles for the treatment of demyelinating diseases
|
|
JP7090099B2
(ja)
|
2017-03-16 |
2022-06-23 |
エフ．ホフマン－ラ ロシュ アーゲー |
Ａｔｘインヒビターとしての新規二環式化合物
|
|
RU2019132254A
(ru)
|
2017-03-16 |
2021-04-16 |
Ф. Хоффманн-Ля Рош Аг |
Гетероциклические соединения, пригодные в качестве дуальных ингибиторов atx/ca
|
|
EP3797617B1
(en)
*
|
2018-05-21 |
2026-01-21 |
ASICS Corporation |
Brassiere
|
|
KR102623218B1
(ko)
*
|
2018-08-23 |
2024-01-11 |
가천대학교 산학협력단 |
페닐아세트산 유도체 및 이를 유효성분으로 함유하는 자가면역질환 예방 또는 치료용 조성물
|
|
US12048678B2
(en)
*
|
2018-10-02 |
2024-07-30 |
Case Western Reserve University |
Compounds for treating myelin related disorders
|
|
CA3243968A1
(en)
*
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fused diazepines as insulin-type peptide receptor (INSL3) RXFP2 agonists and their methods of use
|