JP2012532889A - 創傷治療方法及び傷跡変性方法 - Google Patents

創傷治療方法及び傷跡変性方法 Download PDF

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Publication number
JP2012532889A
JP2012532889A JP2012519777A JP2012519777A JP2012532889A JP 2012532889 A JP2012532889 A JP 2012532889A JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012532889 A JP2012532889 A JP 2012532889A
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JP
Japan
Prior art keywords
wound
scar
pharmaceutical composition
corticosteroid
formulation
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Pending
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JP2012519777A
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English (en)
Japanese (ja)
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JP2012532889A5 (https=
Inventor
ケラー、ブライアン、シー．
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Crescendo Therapeutics LLC
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Crescendo Therapeutics LLC
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Application filed by Crescendo Therapeutics LLC filed Critical Crescendo Therapeutics LLC
Publication of JP2012532889A publication Critical patent/JP2012532889A/ja
Publication of JP2012532889A5 publication Critical patent/JP2012532889A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2012519777A 2009-07-09 2010-07-09 創傷治療方法及び傷跡変性方法 Pending JP2012532889A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22440809P 2009-07-09 2009-07-09
US61/224,408 2009-07-09
US22621609P 2009-07-16 2009-07-16
US61/226,216 2009-07-16
PCT/US2010/041576 WO2011006100A1 (en) 2009-07-09 2010-07-09 Method of wound healing and scar modulation

Publications (2)

Publication Number Publication Date
JP2012532889A true JP2012532889A (ja) 2012-12-20
JP2012532889A5 JP2012532889A5 (https=) 2013-09-05

Family

ID=43427950

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012519777A Pending JP2012532889A (ja) 2009-07-09 2010-07-09 創傷治療方法及び傷跡変性方法

Country Status (10)

Country Link
US (1) US20110009374A1 (https=)
EP (1) EP2451280A4 (https=)
JP (1) JP2012532889A (https=)
CN (1) CN102480969A (https=)
AR (1) AR077410A1 (https=)
AU (1) AU2010271205A1 (https=)
BR (1) BR112012001098A2 (https=)
CA (1) CA2767661A1 (https=)
MX (1) MX2012000434A (https=)
WO (1) WO2011006100A1 (https=)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100322875A1 (en) 2009-06-18 2010-12-23 Advanced Bio-Technologies, Inc. Silicone scar treatment preparation
US8623040B2 (en) 2009-07-01 2014-01-07 Alcon Research, Ltd. Phacoemulsification hook tip
WO2012012390A1 (en) 2010-07-19 2012-01-26 Marvphyt Development Llc Botanical composition and methods of manufacture and use
US10258505B2 (en) 2010-09-17 2019-04-16 Alcon Research, Ltd. Balanced phacoemulsification tip
ITMI20111050A1 (it) 2011-06-10 2012-12-11 Sevecom Spa Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali.
CA2837526C (en) 2011-06-24 2019-07-09 Merz Pharma Gmbh & Co. Kgaa Composition comprising an onion extract and liposomes
US9364510B2 (en) 2011-07-19 2016-06-14 Marvphyt Development Llc Botanical composition and methods of manufacture and use
SMT201800171T1 (it) 2011-07-29 2018-07-17 Karyopharm Therapeutics Inc Modulatori di trasporto nucleare contenenti idrazide e loro usi
CN104080458B (zh) * 2011-09-13 2020-06-02 布莱阿姆青年大学 用于组织创伤的愈合的产品
US9474685B2 (en) 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
GB201120724D0 (en) * 2011-12-01 2012-01-11 Gauthier Rene System and method for alleviating the appearance of scars and/or scar tissue
FR2985064B1 (fr) * 2011-12-23 2016-02-26 Oreal Procede pour delivrer un conseil cosmetique
EP2841106A1 (en) * 2012-04-27 2015-03-04 Dow Corning Corporation Topical formulation compositions containing silicone based excipients to deliver actives to a substrate
CA2872190C (en) 2012-05-09 2024-06-25 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
US11458199B2 (en) * 2012-08-21 2022-10-04 Opko Pharmaceuticals, Llc Liposome formulations
US9808654B2 (en) * 2013-02-11 2017-11-07 Jan Marini Skin Research Post procedure skin care gel and methods of use thereof
US10202366B2 (en) * 2013-03-15 2019-02-12 Karyopharm Therapeutics Inc. Methods of promoting wound healing using CRM1 inhibitors
WO2014175861A1 (en) * 2013-04-23 2014-10-30 Hewlett-Packard Development Company, L.P. Recovering from compromised system boot code
DK3492455T3 (da) 2013-06-21 2023-08-14 Karyopharm Therapeutics Inc 1,2,4-triazoler som nukleare transportmodulatorer og anvendelse til behandling af specifikke former for cancer
US11432990B2 (en) 2013-08-30 2022-09-06 ISOS Solutions, LLC Textured apparatus with therapeutic material incorporated therein and methods of manufacturing same
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
WO2015099660A1 (en) * 2013-12-23 2015-07-02 Intel Corporation Integrated component interconnect
WO2015189712A2 (en) 2014-06-09 2015-12-17 Klox Technologies Inc. Silicone-based biophotonic compositions and uses thereof
MA40433A (fr) 2014-07-21 2017-06-14 Sevecom Spa Émulsion en poudre pour aliments pour animaux
CN111484483B (zh) 2014-08-15 2023-05-26 卡尔约药物治疗公司 赛灵克斯的多晶型物
WO2017117535A1 (en) 2015-12-31 2017-07-06 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
US10526295B2 (en) 2015-12-31 2020-01-07 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
US11602530B2 (en) 2016-11-28 2023-03-14 Biogen Ma Inc. CRM1 inhibitors for treating epilepsy
JP7595413B2 (ja) 2016-11-30 2024-12-06 ケース ウエスタン リザーブ ユニバーシティ １５－ｐｇｄｈ阻害剤とコルチコステロイドおよび／またはｔｎｆ阻害剤との組み合わせならびにその使用
WO2018145080A1 (en) 2017-02-06 2018-08-09 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase activity
CN113453670A (zh) * 2018-09-28 2021-09-28 乔·斯图丁 类固醇和大分子的透孔递送
CN120463721A (zh) 2018-11-21 2025-08-12 卡斯西部储备大学 调节短链脱氢酶活性的组合物和方法
US20200397720A1 (en) * 2019-06-23 2020-12-24 Charles Huntington Gallina Method and formulation for treatment of wounds by new tissue regeneration with reduced trauma and scar tissue formation
CN110368498A (zh) * 2019-08-26 2019-10-25 瑞希(重庆)生物科技有限公司 一种促进伤口愈合的制剂及其制备方法
US20240180812A1 (en) * 2022-07-27 2024-06-06 Bio Med Sciences, Inc. Method of improving outcomes of dermal tattoos and tattoo removal procedures

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010068955A (ko) * 2000-01-11 2001-07-23 조용준 외피용약제 조성물
JP2003081812A (ja) * 2001-07-05 2003-03-19 Rohto Pharmaceut Co Ltd エアゾール製剤
JP2003514835A (ja) * 1999-11-17 2003-04-22 ディ・エスジー・ライセンシング・コーポレイション 瘢痕を治療する方法と組成物
JP2003321347A (ja) * 2002-05-07 2003-11-11 Rohto Pharmaceut Co Ltd ゲル軟膏
JP2006521356A (ja) * 2003-03-28 2006-09-21 ファルマシア・コーポレーション シクロオキシゲナーゼ−２阻害薬を使用することによるステロイド節約効果をもたらす方法、およびシクロオキシゲナーゼ−２阻害薬を含む組成物
JP2008502647A (ja) * 2004-06-17 2008-01-31 ガルデルマ・ソシエテ・アノニム シリコーン剤、コルチコステロイドおよびビタミンｄまたはその誘導体を含む乾癬治療用組成物
WO2008109887A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089464A1 (en) * 2000-05-23 2001-11-29 Unilever Plc Deodorant and/or antiperspirant compositions
GB0018466D0 (en) * 2000-07-27 2000-09-13 Strakan Pharm Ltd Keloid Treatment
US6610322B1 (en) * 2000-12-20 2003-08-26 Brian Charles Keller Self forming, thermodynamically stable liposomes and their applications
US6495596B1 (en) * 2001-03-23 2002-12-17 Biozibe Laboratories, Inc. Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2
US6998421B2 (en) * 2001-06-07 2006-02-14 Biozone Laboratories, Inc. Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase - 2
GB0216427D0 (en) * 2002-07-16 2002-08-21 Advanced Biotechnologies Inter Wound dressing
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
CN101247787B (zh) * 2005-06-10 2011-10-05 盖尔德玛公司 以包含药物、成膜聚硅氧烷和至少一种挥发性溶剂为基础的经皮药物的控制释放
US20080317830A1 (en) * 2007-06-25 2008-12-25 Liolabs Llc Compositions and Methods for the Treatment of Wounds and Scar Tissue
DE102009030931A1 (de) * 2009-06-24 2010-12-30 Eberhard-Karls-Universität Tübingen Universitätsklinikum Chirurgisches Wundverschlusselement

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003514835A (ja) * 1999-11-17 2003-04-22 ディ・エスジー・ライセンシング・コーポレイション 瘢痕を治療する方法と組成物
KR20010068955A (ko) * 2000-01-11 2001-07-23 조용준 외피용약제 조성물
JP2003081812A (ja) * 2001-07-05 2003-03-19 Rohto Pharmaceut Co Ltd エアゾール製剤
JP2003321347A (ja) * 2002-05-07 2003-11-11 Rohto Pharmaceut Co Ltd ゲル軟膏
JP2006521356A (ja) * 2003-03-28 2006-09-21 ファルマシア・コーポレーション シクロオキシゲナーゼ−２阻害薬を使用することによるステロイド節約効果をもたらす方法、およびシクロオキシゲナーゼ−２阻害薬を含む組成物
JP2008502647A (ja) * 2004-06-17 2008-01-31 ガルデルマ・ソシエテ・アノニム シリコーン剤、コルチコステロイドおよびビタミンｄまたはその誘導体を含む乾癬治療用組成物
WO2008109887A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VOENNO-MEDITSINSKII ZHURNAL, vol. 2, JPN7014002301, 1982, pages 26 - 30, ISSN: 0002865321 *

Also Published As

Publication number Publication date
AU2010271205A1 (en) 2012-02-09
CA2767661A1 (en) 2011-01-13
US20110009374A1 (en) 2011-01-13
MX2012000434A (es) 2012-04-11
EP2451280A1 (en) 2012-05-16
BR112012001098A2 (pt) 2015-09-01
CN102480969A (zh) 2012-05-30
WO2011006100A1 (en) 2011-01-13
AR077410A1 (es) 2011-08-24
EP2451280A4 (en) 2012-12-26

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