JP2012532889A - 創傷治療方法及び傷跡変性方法 - Google Patents

創傷治療方法及び傷跡変性方法 Download PDF

Info

Publication number
JP2012532889A
JP2012532889A JP2012519777A JP2012519777A JP2012532889A JP 2012532889 A JP2012532889 A JP 2012532889A JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012532889 A JP2012532889 A JP 2012532889A
Authority
JP
Japan
Prior art keywords
wound
scar
pharmaceutical composition
corticosteroid
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012519777A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012532889A5 (enExample
Inventor
ケラー、ブライアン、シー.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crescendo Therapeutics LLC
Original Assignee
Crescendo Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crescendo Therapeutics LLC filed Critical Crescendo Therapeutics LLC
Publication of JP2012532889A publication Critical patent/JP2012532889A/ja
Publication of JP2012532889A5 publication Critical patent/JP2012532889A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2012519777A 2009-07-09 2010-07-09 創傷治療方法及び傷跡変性方法 Pending JP2012532889A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22440809P 2009-07-09 2009-07-09
US61/224,408 2009-07-09
US22621609P 2009-07-16 2009-07-16
US61/226,216 2009-07-16
PCT/US2010/041576 WO2011006100A1 (en) 2009-07-09 2010-07-09 Method of wound healing and scar modulation

Publications (2)

Publication Number Publication Date
JP2012532889A true JP2012532889A (ja) 2012-12-20
JP2012532889A5 JP2012532889A5 (enExample) 2013-09-05

Family

ID=43427950

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012519777A Pending JP2012532889A (ja) 2009-07-09 2010-07-09 創傷治療方法及び傷跡変性方法

Country Status (10)

Country Link
US (1) US20110009374A1 (enExample)
EP (1) EP2451280A4 (enExample)
JP (1) JP2012532889A (enExample)
CN (1) CN102480969A (enExample)
AR (1) AR077410A1 (enExample)
AU (1) AU2010271205A1 (enExample)
BR (1) BR112012001098A2 (enExample)
CA (1) CA2767661A1 (enExample)
MX (1) MX2012000434A (enExample)
WO (1) WO2011006100A1 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100322875A1 (en) 2009-06-18 2010-12-23 Advanced Bio-Technologies, Inc. Silicone scar treatment preparation
US8623040B2 (en) 2009-07-01 2014-01-07 Alcon Research, Ltd. Phacoemulsification hook tip
WO2012012390A1 (en) 2010-07-19 2012-01-26 Marvphyt Development Llc Botanical composition and methods of manufacture and use
US10258505B2 (en) 2010-09-17 2019-04-16 Alcon Research, Ltd. Balanced phacoemulsification tip
ITMI20111050A1 (it) 2011-06-10 2012-12-11 Sevecom Spa Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali.
CA2837526C (en) 2011-06-24 2019-07-09 Merz Pharma Gmbh & Co. Kgaa Composition comprising an onion extract and liposomes
US9364510B2 (en) 2011-07-19 2016-06-14 Marvphyt Development Llc Botanical composition and methods of manufacture and use
TWI574957B (zh) 2011-07-29 2017-03-21 佳佑製藥治療公司 含有醯肼的核運輸調控子及其用途
MX369385B (es) * 2011-09-13 2019-11-07 Univ Brigham Young Productos para cicatrizar heridas tisulares.
US9474685B2 (en) 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
GB201120724D0 (en) * 2011-12-01 2012-01-11 Gauthier Rene System and method for alleviating the appearance of scars and/or scar tissue
FR2985064B1 (fr) * 2011-12-23 2016-02-26 Oreal Procede pour delivrer un conseil cosmetique
US20150141389A1 (en) * 2012-04-27 2015-05-21 Dow Corning Corporation Topical Formulation Compositions Containing Silicone Based Excipients To Deliver Actives To A Substrate
RS58058B1 (sr) 2012-05-09 2019-02-28 Biogen Ma Inc Modulatori nukleusnog transporta i njihove upotrebe
US11458199B2 (en) * 2012-08-21 2022-10-04 Opko Pharmaceuticals, Llc Liposome formulations
US9808654B2 (en) * 2013-02-11 2017-11-07 Jan Marini Skin Research Post procedure skin care gel and methods of use thereof
US10202366B2 (en) * 2013-03-15 2019-02-12 Karyopharm Therapeutics Inc. Methods of promoting wound healing using CRM1 inhibitors
US9880908B2 (en) * 2013-04-23 2018-01-30 Hewlett-Packard Development Company, L.P. Recovering from compromised system boot code
DK3010892T3 (en) 2013-06-21 2019-04-15 Karyopharm Therapeutics Inc 1,2,4-TRIAZOLES AS NUCLEAR TRANSPORT MODULATORS AND APPLICATIONS THEREOF
US11432990B2 (en) 2013-08-30 2022-09-06 ISOS Solutions, LLC Textured apparatus with therapeutic material incorporated therein and methods of manufacturing same
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
US10423552B2 (en) * 2013-12-23 2019-09-24 Intel Corporation Integrated component interconnect
CA2951513A1 (en) 2014-06-09 2015-12-17 Klox Technologies Inc. Silicone-based biophotonic compositions and uses thereof
AU2015293628B2 (en) 2014-07-21 2019-06-20 Sevecom S.P.A. Powdered emulsion for animal feed
KR102608259B1 (ko) 2014-08-15 2023-11-29 카리오팜 쎄라퓨틱스, 인코포레이티드 셀리넥소의 다형태
EP3397633A1 (en) 2015-12-31 2018-11-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
WO2017117535A1 (en) 2015-12-31 2017-07-06 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
US11602530B2 (en) 2016-11-28 2023-03-14 Biogen Ma Inc. CRM1 inhibitors for treating epilepsy
WO2018102552A1 (en) * 2016-11-30 2018-06-07 Case Western Reserve University Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof
JP2020514323A (ja) 2017-02-06 2020-05-21 ケース ウエスタン リザーブ ユニバーシティ 短鎖デヒドロゲナーゼ活性を調節する組成物と方法
WO2020069448A1 (en) * 2018-09-28 2020-04-02 Joel Studin Transpore delivery of steroids and large molecules
EA202191422A1 (ru) 2018-11-21 2021-10-21 Кейс Вестерн Ризерв Юниверсити Композиции и способы модулирования активности короткоцепочечной дегидрогеназы
US20200397720A1 (en) * 2019-06-23 2020-12-24 Charles Huntington Gallina Method and formulation for treatment of wounds by new tissue regeneration with reduced trauma and scar tissue formation
CN110368498A (zh) * 2019-08-26 2019-10-25 瑞希(重庆)生物科技有限公司 一种促进伤口愈合的制剂及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010068955A (ko) * 2000-01-11 2001-07-23 조용준 외피용약제 조성물
JP2003081812A (ja) * 2001-07-05 2003-03-19 Rohto Pharmaceut Co Ltd エアゾール製剤
JP2003514835A (ja) * 1999-11-17 2003-04-22 ディ・エスジー・ライセンシング・コーポレイション 瘢痕を治療する方法と組成物
JP2003321347A (ja) * 2002-05-07 2003-11-11 Rohto Pharmaceut Co Ltd ゲル軟膏
JP2006521356A (ja) * 2003-03-28 2006-09-21 ファルマシア・コーポレーション シクロオキシゲナーゼ−2阻害薬を使用することによるステロイド節約効果をもたらす方法、およびシクロオキシゲナーゼ−2阻害薬を含む組成物
JP2008502647A (ja) * 2004-06-17 2008-01-31 ガルデルマ・ソシエテ・アノニム シリコーン剤、コルチコステロイドおよびビタミンdまたはその誘導体を含む乾癬治療用組成物
WO2008109887A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02011440A (es) * 2000-05-23 2003-04-25 Unilever Nv Composiciones desodorantes y/o antitranspirantes.
GB0018466D0 (en) * 2000-07-27 2000-09-13 Strakan Pharm Ltd Keloid Treatment
US6610322B1 (en) * 2000-12-20 2003-08-26 Brian Charles Keller Self forming, thermodynamically stable liposomes and their applications
US6998421B2 (en) * 2001-06-07 2006-02-14 Biozone Laboratories, Inc. Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase - 2
US6495596B1 (en) * 2001-03-23 2002-12-17 Biozibe Laboratories, Inc. Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2
GB0216427D0 (en) * 2002-07-16 2002-08-21 Advanced Biotechnologies Inter Wound dressing
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
RU2008100037A (ru) * 2005-06-10 2009-07-20 Галдерма С.А. (Ch) Способ регулируемого высвобождения лекарственного средства через кожу
US20080317830A1 (en) * 2007-06-25 2008-12-25 Liolabs Llc Compositions and Methods for the Treatment of Wounds and Scar Tissue
DE102009030931A1 (de) * 2009-06-24 2010-12-30 Eberhard-Karls-Universität Tübingen Universitätsklinikum Chirurgisches Wundverschlusselement

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003514835A (ja) * 1999-11-17 2003-04-22 ディ・エスジー・ライセンシング・コーポレイション 瘢痕を治療する方法と組成物
KR20010068955A (ko) * 2000-01-11 2001-07-23 조용준 외피용약제 조성물
JP2003081812A (ja) * 2001-07-05 2003-03-19 Rohto Pharmaceut Co Ltd エアゾール製剤
JP2003321347A (ja) * 2002-05-07 2003-11-11 Rohto Pharmaceut Co Ltd ゲル軟膏
JP2006521356A (ja) * 2003-03-28 2006-09-21 ファルマシア・コーポレーション シクロオキシゲナーゼ−2阻害薬を使用することによるステロイド節約効果をもたらす方法、およびシクロオキシゲナーゼ−2阻害薬を含む組成物
JP2008502647A (ja) * 2004-06-17 2008-01-31 ガルデルマ・ソシエテ・アノニム シリコーン剤、コルチコステロイドおよびビタミンdまたはその誘導体を含む乾癬治療用組成物
WO2008109887A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VOENNO-MEDITSINSKII ZHURNAL, vol. 2, JPN7014002301, 1982, pages 26 - 30, ISSN: 0002865321 *

Also Published As

Publication number Publication date
AR077410A1 (es) 2011-08-24
CA2767661A1 (en) 2011-01-13
AU2010271205A1 (en) 2012-02-09
BR112012001098A2 (pt) 2015-09-01
CN102480969A (zh) 2012-05-30
EP2451280A1 (en) 2012-05-16
MX2012000434A (es) 2012-04-11
WO2011006100A1 (en) 2011-01-13
EP2451280A4 (en) 2012-12-26
US20110009374A1 (en) 2011-01-13

Similar Documents

Publication Publication Date Title
JP2012532889A (ja) 創傷治療方法及び傷跡変性方法
US8945636B2 (en) Stabilized formulation comprising omega-3 fatty acids and use of the fatty acids for skin care and/or wound care
CA2891602C (en) Composition comprising an orthosilicate and its use for tissue regeneration
JP5897164B2 (ja) 外用組成物
US20100105644A1 (en) Botanical composition for enhanced skin repair and uses thereof
TW201210601A (en) Compounds and methods for skin repair
US20110189307A1 (en) Methods and compositions for oxygenation of skin to treat skin disorders
AU2012368815B2 (en) A composition and use thereof in the treatment of anal rhagades
US20220105062A1 (en) Transdermal penetrant formulations
US9555053B2 (en) Use of oligosaccharide compounds for the prevention and treatment of pathological scars
US20080220068A1 (en) Treatment and prevention of excessive scarring
EP2046310B1 (en) Treatment and prevention of excessive scarring
US20140350117A1 (en) Topical Scar Treatment Composition and Method of Using Same
WO2020175131A1 (ja) 脈管異常治療用外用剤
TWI899828B (zh) 乳液、醫藥組成物及外用組成物
TWI862350B (zh) 治療表皮分解性水疱症的方法
EP3079691B1 (en) Pharmaceutical composition comprising dantrolene as ryanodine receptor antagonist for facilitating wound healing
WO2011123619A2 (en) Permeable mixtures, methods and compositions for the skin
KR102113317B1 (ko) 흉터의 예방 또는 치료를 위한 조성물
CN110996977A (zh) 用于缓解或治疗灼伤及褥疮的组合物
CN121129869A (zh) 一种用于皮肤修复的组合物及其制备方法和应用
TW202529729A (zh) 乳液、醫藥組成物及外用組成物
RU2578969C1 (ru) Средство для лечения повреждений наружных тканей организма (варианты) и способ его получения
EP1891945A1 (en) Treatment and prevention of excessive scarring
HK1130434B (en) Treatment and prevention of excessive scarring

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130705

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130705

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140729

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141029

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141106

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141118

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141126

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141225

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150407