JP2012532889A5 - - Google Patents
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- JP2012532889A5 JP2012532889A5 JP2012519777A JP2012519777A JP2012532889A5 JP 2012532889 A5 JP2012532889 A5 JP 2012532889A5 JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012519777 A JP2012519777 A JP 2012519777A JP 2012532889 A5 JP2012532889 A5 JP 2012532889A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- silicone
- days
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008194 pharmaceutical composition Substances 0.000 claims description 25
- 229920001296 polysiloxane Polymers 0.000 claims description 10
- 239000003246 corticosteroid Substances 0.000 claims description 7
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 5
- 229940121363 anti-inflammatory agent Drugs 0.000 claims description 5
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 5
- 229940008099 dimethicone Drugs 0.000 claims description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 5
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 5
- 231100000241 scar Toxicity 0.000 claims description 4
- 229940086555 cyclomethicone Drugs 0.000 claims description 3
- 229920002545 silicone oil Polymers 0.000 claims description 3
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical group CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 claims description 2
- 229940093444 Cyclooxygenase 2 inhibitor Drugs 0.000 claims description 2
- 102000015439 Phospholipases Human genes 0.000 claims description 2
- 108010064785 Phospholipases Proteins 0.000 claims description 2
- LRJOMUJRLNCICJ-JZYPGELDSA-N Prednisolone acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O LRJOMUJRLNCICJ-JZYPGELDSA-N 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 claims description 2
- 229960001293 methylprednisolone acetate Drugs 0.000 claims description 2
- PLBHSZGDDKCEHR-LFYFAGGJSA-N methylprednisolone acetate Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)COC(C)=O)CC[C@H]21 PLBHSZGDDKCEHR-LFYFAGGJSA-N 0.000 claims description 2
- 229960002800 prednisolone acetate Drugs 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims 4
- -1 thixocortol Chemical compound 0.000 claims 4
- 239000004744 fabric Substances 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 229960001334 corticosteroids Drugs 0.000 claims 2
- 229960003662 desonide Drugs 0.000 claims 2
- WBGKWQHBNHJJPZ-LECWWXJVSA-N desonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O WBGKWQHBNHJJPZ-LECWWXJVSA-N 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 claims 1
- VHRSUDSXCMQTMA-PJHHCJLFSA-N 6alpha-methylprednisolone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)CO)CC[C@H]21 VHRSUDSXCMQTMA-PJHHCJLFSA-N 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 claims 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 claims 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 claims 1
- WJOHZNCJWYWUJD-IUGZLZTKSA-N Fluocinonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)COC(=O)C)[C@@]2(C)C[C@@H]1O WJOHZNCJWYWUJD-IUGZLZTKSA-N 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- 229960004436 budesonide Drugs 0.000 claims 1
- 229960002842 clobetasol Drugs 0.000 claims 1
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 claims 1
- 229960004544 cortisone Drugs 0.000 claims 1
- 229960002593 desoximetasone Drugs 0.000 claims 1
- VWVSBHGCDBMOOT-IIEHVVJPSA-N desoximetasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@@H]2O VWVSBHGCDBMOOT-IIEHVVJPSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229960002011 fludrocortisone Drugs 0.000 claims 1
- AAXVEMMRQDVLJB-BULBTXNYSA-N fludrocortisone Chemical compound O=C1CC[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 AAXVEMMRQDVLJB-BULBTXNYSA-N 0.000 claims 1
- 229940043075 fluocinolone Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- 229960000785 fluocinonide Drugs 0.000 claims 1
- 229960002714 fluticasone Drugs 0.000 claims 1
- MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 claims 1
- 229940115747 halobetasol Drugs 0.000 claims 1
- 229960000890 hydrocortisone Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229960004584 methylprednisolone Drugs 0.000 claims 1
- 229960001664 mometasone Drugs 0.000 claims 1
- QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 claims 1
- 229940086541 peg-12 glyceryl dimyristate Drugs 0.000 claims 1
- 229960002794 prednicarbate Drugs 0.000 claims 1
- FNPXMHRZILFCKX-KAJVQRHHSA-N prednicarbate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)CC)(OC(=O)OCC)[C@@]1(C)C[C@@H]2O FNPXMHRZILFCKX-KAJVQRHHSA-N 0.000 claims 1
- 229960005205 prednisolone Drugs 0.000 claims 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims 1
- 229960004618 prednisone Drugs 0.000 claims 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 claims 1
- 229960005294 triamcinolone Drugs 0.000 claims 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 1
- LEHFPXVYPMWYQD-XHIJKXOTSA-N ulobetasol Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]2(C)C[C@@H]1O LEHFPXVYPMWYQD-XHIJKXOTSA-N 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 description 5
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22440809P | 2009-07-09 | 2009-07-09 | |
| US61/224,408 | 2009-07-09 | ||
| US22621609P | 2009-07-16 | 2009-07-16 | |
| US61/226,216 | 2009-07-16 | ||
| PCT/US2010/041576 WO2011006100A1 (en) | 2009-07-09 | 2010-07-09 | Method of wound healing and scar modulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012532889A JP2012532889A (ja) | 2012-12-20 |
| JP2012532889A5 true JP2012532889A5 (enExample) | 2013-09-05 |
Family
ID=43427950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012519777A Pending JP2012532889A (ja) | 2009-07-09 | 2010-07-09 | 創傷治療方法及び傷跡変性方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110009374A1 (enExample) |
| EP (1) | EP2451280A4 (enExample) |
| JP (1) | JP2012532889A (enExample) |
| CN (1) | CN102480969A (enExample) |
| AR (1) | AR077410A1 (enExample) |
| AU (1) | AU2010271205A1 (enExample) |
| BR (1) | BR112012001098A2 (enExample) |
| CA (1) | CA2767661A1 (enExample) |
| MX (1) | MX2012000434A (enExample) |
| WO (1) | WO2011006100A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100322875A1 (en) | 2009-06-18 | 2010-12-23 | Advanced Bio-Technologies, Inc. | Silicone scar treatment preparation |
| US8623040B2 (en) | 2009-07-01 | 2014-01-07 | Alcon Research, Ltd. | Phacoemulsification hook tip |
| WO2012012390A1 (en) | 2010-07-19 | 2012-01-26 | Marvphyt Development Llc | Botanical composition and methods of manufacture and use |
| US10258505B2 (en) | 2010-09-17 | 2019-04-16 | Alcon Research, Ltd. | Balanced phacoemulsification tip |
| ITMI20111050A1 (it) | 2011-06-10 | 2012-12-11 | Sevecom Spa | Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali. |
| CA2837526C (en) | 2011-06-24 | 2019-07-09 | Merz Pharma Gmbh & Co. Kgaa | Composition comprising an onion extract and liposomes |
| US9364510B2 (en) | 2011-07-19 | 2016-06-14 | Marvphyt Development Llc | Botanical composition and methods of manufacture and use |
| TWI574957B (zh) | 2011-07-29 | 2017-03-21 | 佳佑製藥治療公司 | 含有醯肼的核運輸調控子及其用途 |
| MX369385B (es) * | 2011-09-13 | 2019-11-07 | Univ Brigham Young | Productos para cicatrizar heridas tisulares. |
| US9474685B2 (en) | 2011-09-28 | 2016-10-25 | Sure-Shot Medical Device Inc. | Apparatus for localized dermatological treatment |
| GB201120724D0 (en) * | 2011-12-01 | 2012-01-11 | Gauthier Rene | System and method for alleviating the appearance of scars and/or scar tissue |
| FR2985064B1 (fr) * | 2011-12-23 | 2016-02-26 | Oreal | Procede pour delivrer un conseil cosmetique |
| US20150141389A1 (en) * | 2012-04-27 | 2015-05-21 | Dow Corning Corporation | Topical Formulation Compositions Containing Silicone Based Excipients To Deliver Actives To A Substrate |
| RS58058B1 (sr) | 2012-05-09 | 2019-02-28 | Biogen Ma Inc | Modulatori nukleusnog transporta i njihove upotrebe |
| US11458199B2 (en) * | 2012-08-21 | 2022-10-04 | Opko Pharmaceuticals, Llc | Liposome formulations |
| US9808654B2 (en) * | 2013-02-11 | 2017-11-07 | Jan Marini Skin Research | Post procedure skin care gel and methods of use thereof |
| US10202366B2 (en) * | 2013-03-15 | 2019-02-12 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using CRM1 inhibitors |
| US9880908B2 (en) * | 2013-04-23 | 2018-01-30 | Hewlett-Packard Development Company, L.P. | Recovering from compromised system boot code |
| DK3010892T3 (en) | 2013-06-21 | 2019-04-15 | Karyopharm Therapeutics Inc | 1,2,4-TRIAZOLES AS NUCLEAR TRANSPORT MODULATORS AND APPLICATIONS THEREOF |
| US11432990B2 (en) | 2013-08-30 | 2022-09-06 | ISOS Solutions, LLC | Textured apparatus with therapeutic material incorporated therein and methods of manufacturing same |
| US9226890B1 (en) | 2013-12-10 | 2016-01-05 | Englewood Lab, Llc | Polysilicone base for scar treatment |
| US10423552B2 (en) * | 2013-12-23 | 2019-09-24 | Intel Corporation | Integrated component interconnect |
| CA2951513A1 (en) | 2014-06-09 | 2015-12-17 | Klox Technologies Inc. | Silicone-based biophotonic compositions and uses thereof |
| AU2015293628B2 (en) | 2014-07-21 | 2019-06-20 | Sevecom S.P.A. | Powdered emulsion for animal feed |
| KR102608259B1 (ko) | 2014-08-15 | 2023-11-29 | 카리오팜 쎄라퓨틱스, 인코포레이티드 | 셀리넥소의 다형태 |
| EP3397633A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| WO2017117535A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| US11602530B2 (en) | 2016-11-28 | 2023-03-14 | Biogen Ma Inc. | CRM1 inhibitors for treating epilepsy |
| WO2018102552A1 (en) * | 2016-11-30 | 2018-06-07 | Case Western Reserve University | Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof |
| JP2020514323A (ja) | 2017-02-06 | 2020-05-21 | ケース ウエスタン リザーブ ユニバーシティ | 短鎖デヒドロゲナーゼ活性を調節する組成物と方法 |
| WO2020069448A1 (en) * | 2018-09-28 | 2020-04-02 | Joel Studin | Transpore delivery of steroids and large molecules |
| EA202191422A1 (ru) | 2018-11-21 | 2021-10-21 | Кейс Вестерн Ризерв Юниверсити | Композиции и способы модулирования активности короткоцепочечной дегидрогеназы |
| US20200397720A1 (en) * | 2019-06-23 | 2020-12-24 | Charles Huntington Gallina | Method and formulation for treatment of wounds by new tissue regeneration with reduced trauma and scar tissue formation |
| CN110368498A (zh) * | 2019-08-26 | 2019-10-25 | 瑞希(重庆)生物科技有限公司 | 一种促进伤口愈合的制剂及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6337076B1 (en) * | 1999-11-17 | 2002-01-08 | Sg Licensing Corporation | Method and composition for the treatment of scars |
| KR100362924B1 (ko) * | 2000-01-11 | 2002-11-30 | 주식회사 동구약품 | 외피용약제 조성물 |
| MXPA02011440A (es) * | 2000-05-23 | 2003-04-25 | Unilever Nv | Composiciones desodorantes y/o antitranspirantes. |
| GB0018466D0 (en) * | 2000-07-27 | 2000-09-13 | Strakan Pharm Ltd | Keloid Treatment |
| US6610322B1 (en) * | 2000-12-20 | 2003-08-26 | Brian Charles Keller | Self forming, thermodynamically stable liposomes and their applications |
| US6998421B2 (en) * | 2001-06-07 | 2006-02-14 | Biozone Laboratories, Inc. | Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase - 2 |
| US6495596B1 (en) * | 2001-03-23 | 2002-12-17 | Biozibe Laboratories, Inc. | Compounds and methods for inhibition of phospholipase A2 and cyclooxygenase-2 |
| JP4450545B2 (ja) * | 2001-07-05 | 2010-04-14 | ロート製薬株式会社 | エアゾール製剤 |
| JP4549006B2 (ja) * | 2002-05-07 | 2010-09-22 | ロート製薬株式会社 | ゲル軟膏 |
| GB0216427D0 (en) * | 2002-07-16 | 2002-08-21 | Advanced Biotechnologies Inter | Wound dressing |
| US20040220155A1 (en) * | 2003-03-28 | 2004-11-04 | Pharmacia Corporation | Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith |
| WO2005009342A2 (en) * | 2003-07-16 | 2005-02-03 | Pharmacia Corporation | Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith |
| JP2008502647A (ja) * | 2004-06-17 | 2008-01-31 | ガルデルマ・ソシエテ・アノニム | シリコーン剤、コルチコステロイドおよびビタミンｄまたはその誘導体を含む乾癬治療用組成物 |
| RU2008100037A (ru) * | 2005-06-10 | 2009-07-20 | Галдерма С.А. (Ch) | Способ регулируемого высвобождения лекарственного средства через кожу |
| MX2009009557A (es) * | 2007-03-08 | 2010-08-10 | Crescendo Therapeutics Llc | Formulaciones de aposito para prevenir o reducir la cicatrizacion. |
| US20080317830A1 (en) * | 2007-06-25 | 2008-12-25 | Liolabs Llc | Compositions and Methods for the Treatment of Wounds and Scar Tissue |
| DE102009030931A1 (de) * | 2009-06-24 | 2010-12-30 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Chirurgisches Wundverschlusselement |
-
2010
- 2010-07-09 AU AU2010271205A patent/AU2010271205A1/en not_active Abandoned
- 2010-07-09 EP EP10797937A patent/EP2451280A4/en not_active Withdrawn
- 2010-07-09 BR BRBR112012001098-0A patent/BR112012001098A2/pt not_active IP Right Cessation
- 2010-07-09 WO PCT/US2010/041576 patent/WO2011006100A1/en not_active Ceased
- 2010-07-09 CN CN2010800392366A patent/CN102480969A/zh active Pending
- 2010-07-09 US US12/833,902 patent/US20110009374A1/en not_active Abandoned
- 2010-07-09 JP JP2012519777A patent/JP2012532889A/ja active Pending
- 2010-07-09 MX MX2012000434A patent/MX2012000434A/es not_active Application Discontinuation
- 2010-07-09 CA CA2767661A patent/CA2767661A1/en not_active Abandoned
- 2010-07-12 AR ARP100102522A patent/AR077410A1/es unknown
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