JP2012532612A5 - - Google Patents
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- JP2012532612A5 JP2012532612A5 JP2012519765A JP2012519765A JP2012532612A5 JP 2012532612 A5 JP2012532612 A5 JP 2012532612A5 JP 2012519765 A JP2012519765 A JP 2012519765A JP 2012519765 A JP2012519765 A JP 2012519765A JP 2012532612 A5 JP2012532612 A5 JP 2012532612A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- slow
- cell
- aptamer
- rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/499,967 | 2009-07-09 | ||
| US12/499,967 US7964356B2 (en) | 2007-01-16 | 2009-07-09 | Method for generating aptamers with improved off-rates |
| PCT/US2010/041540 WO2011006075A1 (en) | 2009-07-09 | 2010-07-09 | Method for generating aptamers with improved off-rates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015215544A Division JP2016065872A (ja) | 2009-07-09 | 2015-11-02 | 向上したオフ速度を有するアプタマーを生成するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532612A JP2012532612A (ja) | 2012-12-20 |
| JP2012532612A5 true JP2012532612A5 (enExample) | 2013-08-29 |
| JP5926178B2 JP5926178B2 (ja) | 2016-05-25 |
Family
ID=43429566
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012519765A Active JP5926178B2 (ja) | 2009-07-09 | 2010-07-09 | 向上したオフ速度を有するアプタマーを生成するための方法 |
| JP2015215544A Pending JP2016065872A (ja) | 2009-07-09 | 2015-11-02 | 向上したオフ速度を有するアプタマーを生成するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015215544A Pending JP2016065872A (ja) | 2009-07-09 | 2015-11-02 | 向上したオフ速度を有するアプタマーを生成するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7964356B2 (enExample) |
| EP (1) | EP2451981B1 (enExample) |
| JP (2) | JP5926178B2 (enExample) |
| AU (1) | AU2010271271B2 (enExample) |
| CA (2) | CA2982304A1 (enExample) |
| ES (1) | ES2610633T3 (enExample) |
| WO (1) | WO2011006075A1 (enExample) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7964356B2 (en) | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US7855054B2 (en) * | 2007-01-16 | 2010-12-21 | Somalogic, Inc. | Multiplexed analyses of test samples |
| US8586303B1 (en) | 2007-01-22 | 2013-11-19 | Steven Albert Benner | In vitro selection with expanded genetic alphabets |
| US9725713B1 (en) | 2007-01-22 | 2017-08-08 | Steven A Benner | In vitro selection with expanded genetic alphabets |
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| US8906700B2 (en) | 2007-11-06 | 2014-12-09 | Ambergen, Inc. | Methods and compositions for phototransfer |
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| WO2016022696A1 (en) | 2014-08-05 | 2016-02-11 | The Trustees Of Columbia University In The City Of New York | Method of isolating aptamers for minimal residual disease detection |
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| US10577609B2 (en) * | 2016-03-07 | 2020-03-03 | Postech Academy—Industry Foundation | Glypican-3 specific aptamer and use thereof |
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| JP2019531351A (ja) | 2016-10-14 | 2019-10-31 | シーエヌエス バイオサイエンシーズ，インコーポレイティド | 脊髄損傷者における神経障害性疼痛の治療 |
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| US20210140977A1 (en) | 2018-04-16 | 2021-05-13 | University Of Cape Town | A three-protein proteomic biomarker for prospective determination of risk for development of active tuberculosis |
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| JP7323162B2 (ja) * | 2019-06-27 | 2023-08-08 | 株式会社アドバンジェン | 核酸アプタマー |
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| IL305336B2 (en) | 2021-03-11 | 2025-09-01 | Nautilus Subsidiary Inc | Systems and methods for preserving biomolecules |
| EP4294920A4 (en) | 2021-04-27 | 2025-01-22 | Singular Genomics Systems, Inc. | HIGH-DENSITY SEQUENCING AND MULTIPLEX PRIMING |
| EP4399528A1 (en) | 2021-09-09 | 2024-07-17 | Nautilus Subsidiary, Inc. | Characterization and localization of protein modifications |
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| WO2023066881A1 (en) | 2021-10-18 | 2023-04-27 | Astrazeneca Ab | Inhibition of map3k15 for treating and preventing diabetes |
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| EP4619766A1 (en) | 2022-11-15 | 2025-09-24 | Nautilus Subsidiary, Inc. | Standard polypeptides |
| EP4630816A1 (en) | 2022-12-09 | 2025-10-15 | Nautilus Subsidiary, Inc. | A method comprising performing on a single-analyte array at least 50 cycles of a process |
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| CN121336096A (zh) | 2023-07-06 | 2026-01-13 | 私募蛋白质体操作有限公司 | 干燥生物基质中的靶分子的检测 |
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| US20250189519A1 (en) | 2023-12-11 | 2025-06-12 | Nautilus Subsidiary, Inc. | Methods and compositions of particle-based arrays |
| WO2025137166A1 (en) | 2023-12-20 | 2025-06-26 | Nautilus Subsidiary, Inc. | Fluidic devices for single-analyte assays |
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| US20250298016A1 (en) | 2024-03-22 | 2025-09-25 | Nautilus Subsidiary, Inc. | Plasmonic particle systems for single-analyte assays |
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-
2009
- 2009-07-09 US US12/499,967 patent/US7964356B2/en active Active
-
2010
- 2010-07-09 CA CA2982304A patent/CA2982304A1/en not_active Abandoned
- 2010-07-09 CA CA2765857A patent/CA2765857C/en active Active
- 2010-07-09 JP JP2012519765A patent/JP5926178B2/ja active Active
- 2010-07-09 AU AU2010271271A patent/AU2010271271B2/en active Active
- 2010-07-09 EP EP10797920.5A patent/EP2451981B1/en active Active
- 2010-07-09 ES ES10797920.5T patent/ES2610633T3/es active Active
- 2010-07-09 WO PCT/US2010/041540 patent/WO2011006075A1/en not_active Ceased
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2015
- 2015-11-02 JP JP2015215544A patent/JP2016065872A/ja active Pending
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