JP2012532134A5 - - Google Patents
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- Publication number
- JP2012532134A5 JP2012532134A5 JP2012518575A JP2012518575A JP2012532134A5 JP 2012532134 A5 JP2012532134 A5 JP 2012532134A5 JP 2012518575 A JP2012518575 A JP 2012518575A JP 2012518575 A JP2012518575 A JP 2012518575A JP 2012532134 A5 JP2012532134 A5 JP 2012532134A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- amino acid
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 30
- 239000012634 fragment Substances 0.000 claims 29
- 229920001184 polypeptide Polymers 0.000 claims 29
- 102000004196 processed proteins & peptides Human genes 0.000 claims 29
- 108090000765 processed proteins & peptides Proteins 0.000 claims 29
- 238000009472 formulation Methods 0.000 claims 28
- 229960005486 vaccine Drugs 0.000 claims 28
- 230000002163 immunogen Effects 0.000 claims 27
- 125000003275 alpha amino acid group Chemical group 0.000 claims 18
- 239000003937 drug carrier Substances 0.000 claims 5
- 239000002671 adjuvant Substances 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 229940123384 Toll-like receptor (TLR) agonist Drugs 0.000 claims 1
- 229940037003 alum Drugs 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22154109P | 2009-06-29 | 2009-06-29 | |
| US61/221,541 | 2009-06-29 | ||
| US24059809P | 2009-09-08 | 2009-09-08 | |
| US24061609P | 2009-09-08 | 2009-09-08 | |
| US61/240,598 | 2009-09-08 | ||
| US61/240,616 | 2009-09-08 | ||
| US31626710P | 2010-03-22 | 2010-03-22 | |
| US61/316,267 | 2010-03-22 | ||
| PCT/US2010/040406 WO2011008548A1 (en) | 2009-06-29 | 2010-06-29 | Vaccines and compositions against streptococcus pneumoniae |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532134A JP2012532134A (ja) | 2012-12-13 |
| JP2012532134A5 true JP2012532134A5 (enExample) | 2014-04-03 |
| JP5931724B2 JP5931724B2 (ja) | 2016-06-08 |
Family
ID=43449681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012518575A Expired - Fee Related JP5931724B2 (ja) | 2009-06-29 | 2010-06-29 | ＳｔｒｅｐｔｏｃｏｃｃｕｓＰｎｅｕｍｏｎｉａｅに対するワクチンおよび組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10105412B2 (enExample) |
| EP (1) | EP2448592B1 (enExample) |
| JP (1) | JP5931724B2 (enExample) |
| KR (1) | KR101748453B1 (enExample) |
| CN (2) | CN102548572A (enExample) |
| AU (1) | AU2010273708B2 (enExample) |
| BR (1) | BRPI1011919A2 (enExample) |
| CA (1) | CA2803061A1 (enExample) |
| IL (1) | IL217166A0 (enExample) |
| IN (1) | IN2012DN00791A (enExample) |
| MX (1) | MX2012000158A (enExample) |
| NZ (1) | NZ597858A (enExample) |
| RU (1) | RU2580299C2 (enExample) |
| SG (2) | SG177402A1 (enExample) |
| WO (1) | WO2011008548A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1011919A2 (pt) | 2009-06-29 | 2017-09-26 | Childrens Medical Center | vacinas e composições contra streptococcus pneumoniae |
| EP2550289A4 (en) | 2010-03-12 | 2013-11-27 | Childrens Medical Center | NEW IMMUNOGENES AND METHODS FOR IDENTIFICATION AND SCREENING THEREOF |
| WO2012085099A1 (en) * | 2010-12-21 | 2012-06-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Determination of the efficacy of an anti-mycobacterial vaccination |
| EP2665490B1 (en) | 2011-01-20 | 2020-03-04 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
| TW201249824A (en) | 2011-03-09 | 2012-12-16 | Glaxosmithkline Llc | Peptide deformylase inhibitors |
| AU2012253327B2 (en) | 2011-05-11 | 2017-05-25 | Children's Medical Center Corporation | Modified biotin-binding protein, fusion proteins thereof and applications |
| AU2013209513B2 (en) * | 2012-01-20 | 2017-10-05 | Children's Medical Center Corporation | Fused antigen vaccines and compositions against Streptococcus pneumoniae |
| WO2014018904A1 (en) * | 2012-07-26 | 2014-01-30 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| WO2014124228A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US20150079132A1 (en) * | 2013-09-17 | 2015-03-19 | Path | Evoking protection against streptotoccus pneumoniae incorporating b-cell and t-cell pneumococcal protein antigens and pneumococcal polysaccharides delivered concomitantly |
| US10881729B2 (en) | 2014-04-18 | 2021-01-05 | Children's Medical Center Corporation | Vaccine adjuvant compositions |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| KR102459629B1 (ko) | 2017-01-20 | 2022-10-28 | 화이자 인코포레이티드 | 폐렴구균 백신에 사용하기 위한 면역원성 조성물 |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| AU2018243910B2 (en) | 2017-03-28 | 2025-04-10 | The Children's Medical Center Corporation | A multiple antigen presenting system (MAPS)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
| CA3067587A1 (en) | 2017-06-23 | 2018-12-27 | Nosocomial Vaccine Corporation | Immunogenic compositions |
| CN120771270A (zh) | 2017-12-04 | 2025-10-14 | 英特维特国际股份有限公司 | 具有复制子颗粒和油佐剂的疫苗 |
| WO2020056127A1 (en) | 2018-09-12 | 2020-03-19 | The Children's Medical Center Corporation | Pneumococcal fusion protein vaccines |
| TW202019470A (zh) | 2018-09-12 | 2020-06-01 | 美商艾芬尼維克斯公司 | 多價肺炎球菌疫苗 |
| RU2728938C1 (ru) * | 2020-05-06 | 2020-08-03 | Федеральное государственное бюджетное учреждение науки "Научный центр биомедицинских технологий Федерального медико-биологического агентства" (ФГБУН НЦБМТ ФМБА России) | Применение даларгина для производства лекарственных средств профилактики пневмонии |
| CN116390747A (zh) | 2020-07-16 | 2023-07-04 | 扎尔瓦克公司 | 链球菌疫苗 |
| KR20240099160A (ko) | 2021-09-09 | 2024-06-28 | 아피니백스, 인크. | 다가 폐렴구균 백신 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| US5371197A (en) | 1991-09-24 | 1994-12-06 | Merck & Co., Inc. | Protein-dimeric polysaccharide conjugate vaccine |
| US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
| EP0907738A1 (en) | 1996-04-02 | 1999-04-14 | Smithkline Beecham Corporation | Novel compounds |
| ATE348887T1 (de) | 1996-10-31 | 2007-01-15 | Human Genome Sciences Inc | Streptococcus pneumoniae antigene und impfstoffe |
| AU735444B2 (en) | 1997-05-06 | 2001-07-05 | Human Genome Sciences, Inc. | (Enterococcus faecalis) polynucleotides and polypeptides |
| CA2294568A1 (en) | 1997-06-20 | 1998-12-30 | Human Genome Sciences, Inc. | Lyme disease vaccines |
| US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US5882885A (en) | 1997-07-17 | 1999-03-16 | Smithkline Beecham Corporation | Glycogen phosphorylase |
| US5994101A (en) | 1997-07-18 | 1999-11-30 | Smithkline Beecham Corporation | DNA encoding gidA1 polypeptides |
| US6617156B1 (en) | 1997-08-15 | 2003-09-09 | Lynn A. Doucette-Stamm | Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics |
| US6248558B1 (en) | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
| EP1144640A3 (en) | 1998-07-27 | 2001-11-28 | Microbial Technics Limited | Nucleic acids and proteins from streptococcus pneumoniae |
| DE60027890T2 (de) | 1999-06-10 | 2007-04-19 | Human Genome Sciences, Inc. | Streptococcus pneumoniae proteine und impfstoffe |
| US6887480B1 (en) | 1999-06-10 | 2005-05-03 | Medimmune, Inc. | Streptococcus pneumoniae proteins and vaccines |
| US6951732B2 (en) | 1999-12-23 | 2005-10-04 | Vmax Ltd. | Virulence genes, proteins, and their use |
| US6783939B2 (en) | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
| WO2002034771A2 (en) * | 2000-10-27 | 2002-05-02 | Chiron Srl | Nucleic acids and proteins from streptococcus groups a & b |
| GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
| CN1636062A (zh) | 2001-04-16 | 2005-07-06 | 惠氏控股公司 | 编码多肽抗原的新肺炎链球菌可读框及其应用 |
| US20040029129A1 (en) | 2001-10-25 | 2004-02-12 | Liangsu Wang | Identification of essential genes in microorganisms |
| US7314974B2 (en) | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
| US20090252756A1 (en) | 2002-04-02 | 2009-10-08 | Yaffa Mizrachi-Nebenzahl | Protein-based streptococcus pneumoniae vaccines |
| WO2003082183A2 (en) | 2002-04-02 | 2003-10-09 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
| US20070053924A1 (en) | 2002-08-26 | 2007-03-08 | Herve Tettelin | Conserved and specific streptococcal genomes |
| AU2003268353A1 (en) | 2002-08-30 | 2004-03-19 | Tufts University | Streptococcus pneumoniae antigens for diagnosis, treatment and prevention of active infection |
| AU2004230244B2 (en) | 2003-04-15 | 2011-09-22 | Intercell Ag | S. pneumoniae antigens |
| GB0318688D0 (en) | 2003-08-08 | 2003-09-10 | Chiron Srl | Streptococcus pneumoniae knockout mutants |
| WO2006069200A2 (en) | 2004-12-22 | 2006-06-29 | Novartis Vaccines And Diagnostics Inc. | Group b streptococcus |
| WO2006084467A1 (en) | 2005-02-11 | 2006-08-17 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides |
| WO2007106407A2 (en) | 2006-03-10 | 2007-09-20 | Wyeth | Microarray for monitoring gene expression in multiple strains of streptococcus pneumoniae |
| ATE522541T1 (de) | 2006-06-09 | 2011-09-15 | Novartis Ag | Bakterielle adhäsine konformere |
| GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
| WO2008119358A2 (en) | 2007-03-30 | 2008-10-09 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides for use in vaccine compositions |
| CN101855362A (zh) | 2007-05-18 | 2010-10-06 | 美国政府健康及人类服务部，疾病控制和预防中心 | 用于检测肺炎链球菌的引物和探针 |
| ES2381613T3 (es) | 2007-05-25 | 2012-05-29 | Novartis Ag | Antígenos de pilus de streptococcus pneumoniae |
| US20100247547A1 (en) | 2007-05-29 | 2010-09-30 | Chen Dong | Modulation of the th-17 cell mediated immune responses |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| CA2699225A1 (en) | 2007-09-14 | 2009-03-19 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
| US7833776B2 (en) | 2007-12-12 | 2010-11-16 | National Health Research Institutes | Lipidating sequences and use thereof for producing lipidated proteins in E. coli |
| US8466259B2 (en) | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| BRPI0908936A2 (pt) * | 2008-03-14 | 2017-03-28 | Sanofi Pasteur Biologics Co | vacinas de flavivírus de replicação defeituosa e vetores de vacina |
| EP3839512A1 (en) | 2008-07-01 | 2021-06-23 | Genocea Biosciences, Inc. | Methods of identifying infections and related conditions |
| WO2010064243A1 (en) | 2008-12-03 | 2010-06-10 | Protea Vaccine Technologies Ltd. | GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS |
| US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| EP2445927B1 (en) | 2009-06-22 | 2014-04-23 | National Health Research Institutes | Lipidated tumor- associated antigens and immunotherapeutic compositions |
| US20120100172A1 (en) | 2009-06-25 | 2012-04-26 | Michael Tal | Immunogenic streptococcus pneumoniae peptides and peptide-multimers |
| BRPI1011919A2 (pt) | 2009-06-29 | 2017-09-26 | Childrens Medical Center | vacinas e composições contra streptococcus pneumoniae |
| WO2011064781A1 (en) | 2009-11-30 | 2011-06-03 | Ben-Gurion University Of The Negev Research And Development Authority | S. pneumoniae adhesins |
| WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
| JP5065434B2 (ja) | 2010-04-06 | 2012-10-31 | 株式会社日立製作所 | 管理方法及び管理装置 |
| WO2011128892A2 (en) | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Modified forms of pneumococcal surface immunogenic protein b (psipb) |
| WO2011141968A1 (en) | 2010-05-14 | 2011-11-17 | Hitachi, Ltd. | Storage apparatus and data retaining method for storage apparatus |
| EP2665490B1 (en) | 2011-01-20 | 2020-03-04 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
-
2010
- 2010-06-29 BR BRPI1011919A patent/BRPI1011919A2/pt not_active IP Right Cessation
- 2010-06-29 SG SG2011096898A patent/SG177402A1/en unknown
- 2010-06-29 CA CA2803061A patent/CA2803061A1/en not_active Abandoned
- 2010-06-29 SG SG10201403702SA patent/SG10201403702SA/en unknown
- 2010-06-29 AU AU2010273708A patent/AU2010273708B2/en not_active Ceased
- 2010-06-29 CN CN2010800388746A patent/CN102548572A/zh active Pending
- 2010-06-29 CN CN201710169055.9A patent/CN107126557A/zh active Pending
- 2010-06-29 EP EP10800303.9A patent/EP2448592B1/en active Active
- 2010-06-29 MX MX2012000158A patent/MX2012000158A/es unknown
- 2010-06-29 JP JP2012518575A patent/JP5931724B2/ja not_active Expired - Fee Related
- 2010-06-29 KR KR1020127001971A patent/KR101748453B1/ko not_active Expired - Fee Related
- 2010-06-29 RU RU2011153032/15A patent/RU2580299C2/ru not_active IP Right Cessation
- 2010-06-29 WO PCT/US2010/040406 patent/WO2011008548A1/en not_active Ceased
- 2010-06-29 NZ NZ597858A patent/NZ597858A/en not_active IP Right Cessation
- 2010-06-29 IN IN791DEN2012 patent/IN2012DN00791A/en unknown
- 2010-06-29 US US12/826,084 patent/US10105412B2/en active Active
-
2011
- 2011-12-22 IL IL217166A patent/IL217166A0/en unknown
-
2018
- 2018-09-17 US US16/133,590 patent/US11207375B2/en active Active
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