JP2012530723A - 筋萎縮性側索硬化症を治療するための組成物及び方法 - Google Patents
筋萎縮性側索硬化症を治療するための組成物及び方法 Download PDFInfo
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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| PCT/US2010/039379 WO2010148409A1 (en) | 2009-06-19 | 2010-06-21 | Compositions and methods for treating amyotrophic lateral sclerosis |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016523981A (ja) * | 2013-07-12 | 2016-08-12 | ノップ バイオサイエンシーズ エルエルシー | 高好酸球値および／または高好塩基球値の治療 |
| US9956206B2 (en) | 2013-02-28 | 2018-05-01 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US10028940B2 (en) | 2013-08-13 | 2018-07-24 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| US10195183B2 (en) | 2013-08-13 | 2019-02-05 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| KR20090021169A (ko) | 2006-05-16 | 2009-02-27 | 크놉 뉴로사이언시스 인코포레이티드 | Ｒ(+) 및 ｓ(-) 프라미펙솔을 포함하는 조성물 및 이의 사용 방법 |
| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| EP2137171A4 (en) | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE |
| US20110190356A1 (en) * | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
| KR101951220B1 (ko) | 2011-07-13 | 2019-02-22 | 싸이토키네틱스, 인코포레이티드 | 조합 als 치료법 |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| WO2013096870A1 (en) * | 2011-12-22 | 2013-06-27 | Knopp Neurosciences Inc | Compositions and methods for treating amyotrophic lateral sclerosis |
| WO2014134569A1 (en) * | 2013-02-28 | 2014-09-04 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| JP2016537360A (ja) * | 2013-11-22 | 2016-12-01 | ジェンザイム・コーポレーション | 神経変性疾患を治療するための新規な方法 |
| US20170248579A1 (en) * | 2014-09-10 | 2017-08-31 | The Uab Research Foundation | Amyotrophic lateral sclerosis (als) biomarkers and uses thereof |
| WO2016207924A1 (en) * | 2015-06-25 | 2016-12-29 | Chiarugi Alberto | Dexpramipexole for the treatment of pain |
| WO2017103224A1 (en) * | 2015-12-16 | 2017-06-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method of treatment of amyotrophic lateral sclerosis |
| WO2021178734A1 (en) * | 2020-03-05 | 2021-09-10 | Biohaven Therapeutics Ltd. | Method of treating amyotrophic lateral sclerosis with myeloperoxidase inhibitor |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005516911A (ja) * | 2001-12-11 | 2005-06-09 | ユニバーシティ オブ バージニア パテント ファウンデーション | 筋萎縮性側索硬化症を処置するためのプラミペキソールの使用 |
| WO2008074033A1 (en) * | 2006-12-14 | 2008-06-19 | Knopp Neurosciences, Inc. | Compositions and methods of using (r)-pramipexole |
| WO2008113003A1 (en) * | 2007-03-14 | 2008-09-18 | Knopp Neurosciences, Inc. | Modified release formulations of (6r)-4,5,6,7-tetrahydro-n6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| JP2009504748A (ja) * | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | Ｒ（＋）プラミペキソールを用いた神経回復 |
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| US4568343A (en) * | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
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| US9956206B2 (en) | 2013-02-28 | 2018-05-01 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US10285981B2 (en) | 2013-02-28 | 2019-05-14 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| JP2016523981A (ja) * | 2013-07-12 | 2016-08-12 | ノップ バイオサイエンシーズ エルエルシー | 高好酸球値および／または高好塩基球値の治療 |
| US10383857B2 (en) | 2013-07-12 | 2019-08-20 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to elevated levels of eosinophils and/or basophils |
| US10028940B2 (en) | 2013-08-13 | 2018-07-24 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| US10195183B2 (en) | 2013-08-13 | 2019-02-05 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| US10456381B2 (en) | 2013-08-13 | 2019-10-29 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2011013577A (es) | 2012-04-10 |
| AU2010262970A1 (en) | 2012-01-12 |
| WO2010148409A1 (en) | 2010-12-23 |
| CL2011003191A1 (es) | 2012-07-20 |
| EP2442655A4 (en) | 2013-04-03 |
| CO6480953A2 (es) | 2012-07-16 |
| CA2765876A1 (en) | 2010-12-23 |
| BRPI1010084A2 (pt) | 2015-08-25 |
| US20130245081A1 (en) | 2013-09-19 |
| US20110009460A1 (en) | 2011-01-13 |
| CN102802418A (zh) | 2012-11-28 |
| RU2012101792A (ru) | 2013-07-27 |
| EP2442655A1 (en) | 2012-04-25 |
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