CL2011003191A1 - Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica. - Google Patents
Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica.Info
- Publication number
- CL2011003191A1 CL2011003191A1 CL2011003191A CL2011003191A CL2011003191A1 CL 2011003191 A1 CL2011003191 A1 CL 2011003191A1 CL 2011003191 A CL2011003191 A CL 2011003191A CL 2011003191 A CL2011003191 A CL 2011003191A CL 2011003191 A1 CL2011003191 A1 CL 2011003191A1
- Authority
- CL
- Chile
- Prior art keywords
- propylamino
- benzothiazole
- tetrahydro
- salts
- amino
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un método para tratar la esclerosis lateral amiotrófica (ALS) que comprende administrar una cantidad efectica de (6r)-2-amino-4,5,6,7-tetrahidro-6-(propilamino) benzotiazol o las sales.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21865909P | 2009-06-19 | 2009-06-19 | |
US26794509P | 2009-12-09 | 2009-12-09 | |
US31711810P | 2010-03-24 | 2010-03-24 | |
US35643910P | 2010-06-18 | 2010-06-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2011003191A1 true CL2011003191A1 (es) | 2012-07-20 |
Family
ID=43356795
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2011003191A CL2011003191A1 (es) | 2009-06-19 | 2011-12-16 | Uso de (6r)-2-amino-4,5,6,7- tetrahidro-6- (propilamino)benzotiazol (dexpramipexol) o sus sales para preparar un medicamento util para tratar la esclerosis lateral amiotrofica. |
Country Status (12)
Country | Link |
---|---|
US (2) | US20110009460A1 (es) |
EP (1) | EP2442655A4 (es) |
JP (1) | JP2012530723A (es) |
CN (1) | CN102802418A (es) |
AU (1) | AU2010262970A1 (es) |
BR (1) | BRPI1010084A2 (es) |
CA (1) | CA2765876A1 (es) |
CL (1) | CL2011003191A1 (es) |
CO (1) | CO6480953A2 (es) |
MX (1) | MX2011013577A (es) |
RU (1) | RU2012101792A (es) |
WO (1) | WO2010148409A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
JP2009537565A (ja) | 2006-05-16 | 2009-10-29 | ノップ ニューロサイエンシーズ、インク. | R(+)およびs(−)プラミペキソール組成とそれを利用する方法 |
US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
EP2137171A4 (en) | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE |
EP2334185A4 (en) | 2008-08-19 | 2011-09-21 | Knopp Neurosciences Inc | COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL |
EA028060B1 (ru) | 2011-07-13 | 2017-10-31 | Сайтокинетикс, Инк. | Комбинированная терапия бокового амиотрофического склероза |
US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
WO2013096870A1 (en) * | 2011-12-22 | 2013-06-27 | Knopp Neurosciences Inc | Compositions and methods for treating amyotrophic lateral sclerosis |
WO2014134569A1 (en) * | 2013-02-28 | 2014-09-04 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
JP6329717B2 (ja) * | 2013-07-12 | 2018-05-23 | ノップ バイオサイエンシーズ エルエルシー | 高好酸球値および/または高好塩基球値の治療 |
EP3033081B1 (en) * | 2013-08-13 | 2021-05-12 | Knopp Biosciences LLC | Compositions and methods for treating chronic urticaria |
WO2015023786A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
EA201691057A1 (ru) * | 2013-11-22 | 2016-10-31 | Джензим Корпорейшн | Новые способы лечения нейродегенеративных заболеваний |
US20170248579A1 (en) * | 2014-09-10 | 2017-08-31 | The Uab Research Foundation | Amyotrophic lateral sclerosis (als) biomarkers and uses thereof |
WO2016207924A1 (en) * | 2015-06-25 | 2016-12-29 | Chiarugi Alberto | Dexpramipexole for the treatment of pain |
WO2017103224A1 (en) * | 2015-12-16 | 2017-06-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method of treatment of amyotrophic lateral sclerosis |
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EP2137171A4 (en) * | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE |
-
2010
- 2010-06-21 RU RU2012101792/15A patent/RU2012101792A/ru unknown
- 2010-06-21 AU AU2010262970A patent/AU2010262970A1/en not_active Abandoned
- 2010-06-21 CA CA2765876A patent/CA2765876A1/en not_active Abandoned
- 2010-06-21 JP JP2012516375A patent/JP2012530723A/ja active Pending
- 2010-06-21 CN CN2010800366747A patent/CN102802418A/zh active Pending
- 2010-06-21 US US12/819,990 patent/US20110009460A1/en not_active Abandoned
- 2010-06-21 BR BRPI1010084-9A patent/BRPI1010084A2/pt not_active IP Right Cessation
- 2010-06-21 MX MX2011013577A patent/MX2011013577A/es not_active Application Discontinuation
- 2010-06-21 EP EP10790329A patent/EP2442655A4/en not_active Withdrawn
- 2010-06-21 WO PCT/US2010/039379 patent/WO2010148409A1/en active Application Filing
-
2011
- 2011-12-16 CL CL2011003191A patent/CL2011003191A1/es unknown
- 2011-12-26 CO CO11178793A patent/CO6480953A2/es not_active Application Discontinuation
-
2012
- 2012-12-20 US US13/722,150 patent/US20130245081A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI1010084A2 (pt) | 2015-08-25 |
CA2765876A1 (en) | 2010-12-23 |
CO6480953A2 (es) | 2012-07-16 |
EP2442655A1 (en) | 2012-04-25 |
WO2010148409A1 (en) | 2010-12-23 |
EP2442655A4 (en) | 2013-04-03 |
US20130245081A1 (en) | 2013-09-19 |
JP2012530723A (ja) | 2012-12-06 |
RU2012101792A (ru) | 2013-07-27 |
AU2010262970A1 (en) | 2012-01-12 |
CN102802418A (zh) | 2012-11-28 |
US20110009460A1 (en) | 2011-01-13 |
MX2011013577A (es) | 2012-04-10 |
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