JP2012530683A5 - - Google Patents
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- Publication number
- JP2012530683A5 JP2012530683A5 JP2011553179A JP2011553179A JP2012530683A5 JP 2012530683 A5 JP2012530683 A5 JP 2012530683A5 JP 2011553179 A JP2011553179 A JP 2011553179A JP 2011553179 A JP2011553179 A JP 2011553179A JP 2012530683 A5 JP2012530683 A5 JP 2012530683A5
- Authority
- JP
- Japan
- Prior art keywords
- skin
- moisture permeability
- function
- agent according
- improving agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000003491 Skin Anatomy 0.000 claims 17
- 230000035699 permeability Effects 0.000 claims 10
- 239000003795 chemical substances by application Substances 0.000 claims 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 229960003190 Adenosine Monophosphate Drugs 0.000 claims 2
- UDMBCSSLTHHNCD-KQYNXXCUSA-N Adenosine monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 claims 2
- 229950006790 Adenosine phosphate Drugs 0.000 claims 2
- 102000011782 Keratins Human genes 0.000 claims 2
- 108010076876 Keratins Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- -1 purine nucleic acid Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 208000003251 Pruritus Diseases 0.000 claims 1
- 208000006641 Skin Disease Diseases 0.000 claims 1
- 206010048218 Xeroderma Diseases 0.000 claims 1
- 206010048222 Xerosis Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 238000005336 cracking Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000005068 transpiration Effects 0.000 claims 1
- 231100001002 xerosis Toxicity 0.000 claims 1
Claims (9)
- アデノシン一リン酸及びその塩からなる群より選択される少なくとも１種のプリン系核酸を有効成分とする皮膚水分透過機能改善剤。
- 皮膚水分透過機能の改善がＴＥＷＬ（経表皮水分蒸散量）の調節によってもたらされることを特徴とする、請求項１に記載の皮膚水分透過機能改善剤。
- ＴＥＷＬが正常でない状態の皮膚症状及び皮膚疾患の予防又は治療用である、請求項１または２に記載の皮膚水分透過機能改善剤。
- 皮膚水分透過機能の異常が老化によるものである、請求項１〜３のいずれかに記載の皮膚水分透過機能改善剤。
- 皮膚水分透過機能の異常が肌荒れ、痒み、ひび割れ、角質肥厚、又は老人性乾皮症である、請求項１〜４のいずれかに記載の皮膚水分透過機能改善剤。
- 皮膚水分透過機能の異常が角質肥厚、又は老人性乾皮症である、請求項１〜５のいずれかに記載の皮膚水分透過機能改善剤。
- 請求項１〜６のいずれかに記載の皮膚水分透過機能改善剤を０．１〜２０重量％含有する、皮膚水分透過機能改善用外用組成物。
- 化粧品、皮膚外用医薬品又は皮膚外用医薬部外品である、請求項７に記載の外用組成物。
- 皮膚水分透過機能を改善するための外用組成物を製造するための、アデノシン一リン酸及びその塩からなる群より選択される少なくとも１種のプリン系核酸の使用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011553179A JP2012530683A (ja) | 2009-06-19 | 2010-06-18 | 皮膚水分透過機能異常の予防又は治療剤 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009146051 | 2009-06-19 | ||
| JP2009146051 | 2009-06-19 | ||
| PCT/JP2010/060796 WO2010147238A1 (en) | 2009-06-19 | 2010-06-18 | Agent for preventing or treating abnormality in skin water permeation function |
| JP2011553179A JP2012530683A (ja) | 2009-06-19 | 2010-06-18 | 皮膚水分透過機能異常の予防又は治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012530683A JP2012530683A (ja) | 2012-12-06 |
| JP2012530683A5 true JP2012530683A5 (ja) | 2013-08-01 |
Family
ID=42752972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553179A Pending JP2012530683A (ja) | 2009-06-19 | 2010-06-18 | 皮膚水分透過機能異常の予防又は治療剤 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2442785A1 (ja) |
| JP (1) | JP2012530683A (ja) |
| KR (1) | KR20120032009A (ja) |
| CN (1) | CN102458351B (ja) |
| HK (1) | HK1166705A1 (ja) |
| WO (1) | WO2010147238A1 (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201607269YA (en) * | 2012-03-05 | 2016-10-28 | Otsuka Pharma Co Ltd | Sunscreen composition |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2844103B2 (ja) * | 1990-02-09 | 1999-01-06 | 株式会社コーセー | 皮膚外用剤 |
| JP3413220B2 (ja) * | 1992-08-17 | 2003-06-03 | 株式会社コーセー | 肌荒れ改善剤 |
| JP3172599B2 (ja) * | 1992-10-16 | 2001-06-04 | 株式会社コーセー | 細胞賦活剤 |
| JP3578858B2 (ja) * | 1995-12-11 | 2004-10-20 | 株式会社ノエビア | 皮膚外用剤 |
| JPH1129457A (ja) * | 1997-07-04 | 1999-02-02 | Kanebo Ltd | 皮膚化粧料 |
| JP2001503447A (ja) * | 1998-04-27 | 2001-03-13 | カラー アクセス，インコーポレイティド | 老化皮膚の処置用組成物および方法 |
| JP4164683B2 (ja) * | 2000-11-22 | 2008-10-15 | 大塚製薬株式会社 | Ｏ／ｗ型乳化組成物及びその調製方法 |
| JP2003206224A (ja) * | 2002-01-08 | 2003-07-22 | Otsuka Pharmaceut Co Ltd | 外用組成物 |
| CA2480080C (en) * | 2002-04-09 | 2010-08-03 | Otsuka Pharmaceutical Co., Ltd. | Composition for cell proliferation |
| JP4084726B2 (ja) * | 2003-09-30 | 2008-04-30 | 丸善製薬株式会社 | コラーゲン合成促進剤、線維芽細胞増殖促進剤、サイクリックａｍｐホスホジエステラーゼ阻害剤、チロシナーゼ阻害剤、及び血小板凝集抑制剤、並びに化粧料及び飲食品。 |
| JP2006225271A (ja) * | 2005-02-15 | 2006-08-31 | Otsuka Pharmaceut Co Ltd | シワの予防又は改善剤 |
| JP4980634B2 (ja) * | 2006-03-17 | 2012-07-18 | ポーラ化成工業株式会社 | 肌荒れの予防、改善に好適な皮膚外用剤 |
| CA2694061C (en) * | 2007-08-06 | 2015-11-03 | Otsuka Pharmaceutical Co., Ltd. | Gel composition for external application containing an adenine compound |
| US9084904B2 (en) * | 2008-01-11 | 2015-07-21 | Otsuka Pharmaceutical Co., Ltd. | Composition for external application |
-
2010
- 2010-06-18 EP EP10728911A patent/EP2442785A1/en not_active Withdrawn
- 2010-06-18 JP JP2011553179A patent/JP2012530683A/ja active Pending
- 2010-06-18 CN CN201080027081.4A patent/CN102458351B/zh not_active Expired - Fee Related
- 2010-06-18 KR KR1020127001387A patent/KR20120032009A/ko not_active Application Discontinuation
- 2010-06-18 WO PCT/JP2010/060796 patent/WO2010147238A1/en active Application Filing
-
2012
- 2012-07-31 HK HK12107452.2A patent/HK1166705A1/xx not_active IP Right Cessation
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