JP2012528858A - O−GlcNAc転移酵素阻害剤およびその使用 - Google Patents

O−GlcNAc転移酵素阻害剤およびその使用 Download PDF

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JP2012528858A
JP2012528858A JP2012513932A JP2012513932A JP2012528858A JP 2012528858 A JP2012528858 A JP 2012528858A JP 2012513932 A JP2012513932 A JP 2012513932A JP 2012513932 A JP2012513932 A JP 2012513932A JP 2012528858 A JP2012528858 A JP 2012528858A
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JP2012528858A5 (enExample
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カーネ,スザンヌ ワルカー
ラザロ,マイケル,ブロック
グロース,ベンジャミン,ジェイ.
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Harvard University
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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JP2012513932A 2009-06-01 2010-06-01 O−GlcNAc転移酵素阻害剤およびその使用 Pending JP2012528858A (ja)

Applications Claiming Priority (3)

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US21751409P 2009-06-01 2009-06-01
US61/217,514 2009-06-01
PCT/US2010/001596 WO2010141074A2 (en) 2009-06-01 2010-06-01 O-glcnac transferase inhibitors and uses thereof

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JP2012528858A true JP2012528858A (ja) 2012-11-15
JP2012528858A5 JP2012528858A5 (enExample) 2014-05-22

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US (1) US8957075B2 (enExample)
EP (1) EP2438046A4 (enExample)
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WO (1) WO2010141074A2 (enExample)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
US8524444B2 (en) 2007-06-15 2013-09-03 President And Fellows Of Harvard College Methods and compositions for detections and modulating O-glycosylation
JP2012528858A (ja) 2009-06-01 2012-11-15 プレジデント アンド フェロウズ オブ ハーバード カレッジ O−GlcNAc転移酵素阻害剤およびその使用
WO2013006758A1 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Diphosphate mimetics and uses thereof
WO2013027168A1 (en) * 2011-08-22 2013-02-28 Pfizer Inc. Novel heterocyclic compounds as bromodomain inhibitors
CN104470515B (zh) 2012-05-03 2016-12-07 圣路易斯药学院 用于增加神经营养肽的组合物和方法
WO2016004180A1 (en) * 2014-07-01 2016-01-07 President And Fellows Of Harvard College O-glcnac transferase (ogt) inhibitors and uses thereof
CN107903185B (zh) * 2017-11-08 2020-05-26 四川大学 新型eEF2K抑制剂的制备及应用
WO2020047251A1 (en) * 2018-08-29 2020-03-05 President And Fellows Of Harvard College O-glcnac transferase inhibitors and uses thereof
TW202130643A (zh) * 2019-10-29 2021-08-16 美商百健Ma公司 螺環o-醣蛋白-2-乙醯胺基-2-去氧-3-d-葡萄哌喃糖苷酶抑制劑
DE102019129527A1 (de) 2019-10-31 2021-05-06 Forschungszentrum Jülich GmbH Inhibitoren für Bromodomänen
KR102571503B1 (ko) * 2020-09-14 2023-08-28 부산대학교 산학협력단 암질환 예방 또는 치료용 조성물

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