JP2012528641A - 積分流(integralflow)分配システムを有する薬用モジュール - Google Patents
積分流(integralflow)分配システムを有する薬用モジュール Download PDFInfo
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Abstract
【選択図】図5
Description
1.薬用針モジュールを、薬用針の近位端が主化合物と流体連通するよう主注射デバイスの遠位端に取り付けること(例えば、主薬物化合物の3mLのカートリッジを含むカートリッジホルダのネジ山付きハブ)。
2.主化合物の所望用量を投与する準備のために、主注射デバイスをダイアル調整/設定すること。
3.薬用針の遠位端を所望の注射サイトに挿入すること。あるデザインにおいて、薬用針の挿入は、第二化合物の送達を起動することができる。
4.用量ボタンを起動することにより、主化合物を投与すること。これは、また、二次化合物を自動的に投与するのを可能にする。
5.薬用針モジュールを取り外すこと、及び廃棄すること。
1.モジュールが使用され、及び取り外されたとき、薬用モジュールの主薬物送達デバイスへの再装着の物理的阻止;
2.使用済み薬物投与インターフェースの患者への挿入の物理的阻止;
(例、単回使用針ガードタイプの配置)
3.薬物投与インターフェースを通した、それを使用したときの、後続液体流の物理的/水圧的阻止;
4.薬物送達デバイスの用量設定器、及び/又は、用量ボタンの物理的ロッキング;
5.可視的警告(例えば、挿入、及び/又は流体流が発生したとき、モジュール上での表示窓内での色の変化、及び/又は、警告文/表示文字(indicia));
6.触覚的フィードバック(次に使用するモジュールハブの外部表面上での触覚的特徴の有無)。
1.第一の薬剤;
2.第二の薬剤/二次薬剤;
3.針;
4.薬用モジュール;
5.主針/係合針;
6a.上部セプタム/膜/シール;
6b.下部セプタム/膜/シール;
7.薬物送達デバイス;
8.取り付け手段/コネクタ;
9.ネジ山;
10.ハウジング;
11.主リザーバ/カートリッジ;
12.用量設定器;
13.用量ボタン;
15a、15b.保持機構;
16.保持キャップ;
17.モジュールの近位端;
19.バイパスチャンネル;
20a、20b.フェルール(ferule);
22.バイアル;
23.フロー分配器/ピン/環状ピン/円筒状ピン;
24.支持リブ;
25.半径方向の羽根;
27、28.チャンネル;
29、30.薬剤の流れ、矢印;
31.カプセル/第二のリザーバ;
32.デバイスの遠位端;
33.キャビティ;
34.下部キャビティ;
Claims (19)
- 薬物送達デバイスに取り付け可能な薬用モジュールであって:
a.近位端及び遠位端を有するハウジング(10)であって、ここで、近位端は、薬物送達デバイス(7)に取り付けるように構成されたコネクタ(8)を有する、該ハウジング(10);
b.薬剤(2)を含むカプセル(31);及び
c.カプセル(31)内に含まれるフロー分配システム(23);
を含んでなる、上記薬用モジュール。 - カプセル(31)が上部及び底部シール(6a、6b)を有する、請求項1に記載の薬用モジュール。
- 薬物送達デバイスに取り付け可能な請求項2に記載の薬用モジュールであって:
d.ハウジング(10)の近位端に位置する保持キャップ(16)に固定された第一の針(5);及び
e.ハウジング(10)の遠位端内に固定された第二の針(3);
を更に含んでなり、ここで、上部及び底部シール(6a、6b)は、第一及び第二の針(5、3)と流体係合するように構成される、上記薬用モジュール。 - カプセル(31)がバイアル(22)を含んでなる、請求項1〜3のいずれか1項に記載の薬用モジュール。
- フロー分配システム(23)がピン(23)を含んでなる、請求項1〜4のいずれか1項に記載の薬用モジュール。
- フロー分配システム(23)が、一つ、二つ又はそれ以上の薬剤フローチャンネル(27、28)を有する、請求項1〜5のいずれか1項に記載の薬用モジュール。
- フロー分配システム(23)が、薬剤の半径方向の流れ(29、30)を発生するように構成される、請求項1〜6のいずれか1項に記載の薬用モジュール。
- フロー分配システム(23)が、一つ又はそれ以上の半径方向の羽根(25)を含んでなる、請求項1〜7のいずれか1項に記載の薬用モジュール。
- カプセル(31)が交換可能である、請求項1〜8のいずれか1項に記載の薬用モジュール。
- カプセル(31)が液体薬剤(2)を含む、請求項1〜9のいずれか1項に記載の薬用モジュール。
- 主リザーバ(11)からの薬剤(1)を、バイパス(19)を通して流動し、そして第二の針(3)から排出することを可能にするバイパスを更に含んでなる、請求項3〜10のいずれか1項に記載の薬用モジュール。
- フロー分配システム(23)及びバイアル(22)が、一体部材として備えられる、請求項1〜11のいずれか1項に記載の薬用モジュール。
- 一体部材が一体成形部材として備えられる、請求項12に記載の薬用モジュール。
- 単回投与インターフェースを通して操作可能である二つ又はそれ以上の薬剤を送達する薬物送達システムであって:
a.少なくとも一つの薬物作用物質を含む薬剤(1)の主リザーバ(11);
b.薬剤(1)の主リザーバ(11)に機能的に連結された用量ボタン(13);
c.主リザーバ(11)に流体連通するように構成された単回投与インターフェース(3);及び
d.i.一つ、二つ、又はそれ以上の薬剤フローチャンネル(27、28)を有するカプセル(31)内のフロー分配システム(23):及び
ii.少なくとも一つの薬剤;
を含んでなるカプセル(31)を含む薬用モジュール(4);
を含んでなり、
ここで、用量ボタン(13)の単回作動が、主リザーバ(11)からの薬剤(1)及びカプセル(31)からの薬剤の少なくとも一回投与量を、単回投与インターフェース(3)を通して放出させる;
上記システム。 - カプセル(31)が少なくとも一つの薬剤の単回用量を含む、請求項14に記載のシステム。
- 用量ボタン(13)の単回起動が、カプセル(31)からの薬剤の使用者設定不可能用量を放出させる、請求項14又は15に記載のシステム。
- 主リザーバ(11)及びカプセル(31)の少なくとも一つが液体薬剤(1、2)を含む、請求項14〜16のいずれか1項に記載の薬用モジュール。
- 主リザーバ(11)がカプセル(31)と流体連通する、請求項14〜17のいずれか1項に記載の薬物送達システム。
- 用量ボタン(13)の作動が、主リザーバ(11)からの薬剤(1)を、カプセル(31)内へ流動させ、そしてそれにより、カプセル(31)からの薬剤を押し出す、請求項18に記載の薬物送達システム。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
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US18345609P | 2009-06-02 | 2009-06-02 | |
US61/183,456 | 2009-06-02 | ||
EP09009656.1 | 2009-07-25 | ||
EP09009656 | 2009-07-25 | ||
US33191310P | 2010-05-06 | 2010-05-06 | |
US61/331,913 | 2010-05-06 | ||
PCT/EP2010/057586 WO2010139676A1 (en) | 2009-06-02 | 2010-06-01 | Medicated module with integral flow distribution system |
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JP2012528641A true JP2012528641A (ja) | 2012-11-15 |
JP5823956B2 JP5823956B2 (ja) | 2015-11-25 |
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JP2012513589A Expired - Fee Related JP5823956B2 (ja) | 2009-06-02 | 2010-06-01 | 積分流(integralflow)分配システムを有する薬用モジュール |
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US (1) | US9352092B2 (ja) |
EP (1) | EP2437807B1 (ja) |
JP (1) | JP5823956B2 (ja) |
CN (1) | CN102458518B (ja) |
AR (1) | AR076721A1 (ja) |
AU (1) | AU2010255762B2 (ja) |
BR (1) | BRPI1013757A2 (ja) |
CA (1) | CA2763069A1 (ja) |
DK (1) | DK2437807T3 (ja) |
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WO (1) | WO2010139676A1 (ja) |
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- 2010-06-01 CN CN2010800320669A patent/CN102458518B/zh not_active Expired - Fee Related
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- 2010-06-01 US US13/322,092 patent/US9352092B2/en active Active
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IL216574A0 (en) | 2012-03-01 |
IL216574A (en) | 2013-12-31 |
CA2763069A1 (en) | 2010-12-09 |
US20120220949A1 (en) | 2012-08-30 |
US9352092B2 (en) | 2016-05-31 |
EP2437807B1 (en) | 2017-07-26 |
AU2010255762B2 (en) | 2015-01-22 |
CN102458518B (zh) | 2013-10-23 |
JP5823956B2 (ja) | 2015-11-25 |
CN102458518A (zh) | 2012-05-16 |
AR076721A1 (es) | 2011-06-29 |
DK2437807T3 (en) | 2017-10-30 |
TW201103590A (en) | 2011-02-01 |
AU2010255762A1 (en) | 2011-12-22 |
EP2437807A1 (en) | 2012-04-11 |
WO2010139676A1 (en) | 2010-12-09 |
BRPI1013757A2 (pt) | 2016-04-05 |
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