JP2012527887A5 - - Google Patents
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- JP2012527887A5 JP2012527887A5 JP2012512547A JP2012512547A JP2012527887A5 JP 2012527887 A5 JP2012527887 A5 JP 2012527887A5 JP 2012512547 A JP2012512547 A JP 2012512547A JP 2012512547 A JP2012512547 A JP 2012512547A JP 2012527887 A5 JP2012527887 A5 JP 2012527887A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- group
- cells
- clone
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000623 proteins and genes Proteins 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 10
- 101150012532 NANOG gene Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 101150033839 4 gene Proteins 0.000 claims 2
- 101100510267 Mus musculus Klf4 gene Proteins 0.000 claims 2
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 2
- 101150086694 SLC22A3 gene Proteins 0.000 claims 2
- 101150037203 Sox2 gene Proteins 0.000 claims 2
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 101150008417 LIN gene Proteins 0.000 claims 1
- 102000006830 Luminescent Proteins Human genes 0.000 claims 1
- 108010047357 Luminescent Proteins Proteins 0.000 claims 1
- 101150039798 MYC gene Proteins 0.000 claims 1
- 208000002352 blister Diseases 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 102000034287 fluorescent proteins Human genes 0.000 claims 1
- 108091006047 fluorescent proteins Proteins 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 101150111214 lin-28 gene Proteins 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108700024542 myc Genes Proteins 0.000 claims 1
- 238000010187 selection method Methods 0.000 claims 1
- 210000001082 somatic cell Anatomy 0.000 claims 1
- 230000005740 tumor formation Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21736209P | 2009-05-29 | 2009-05-29 | |
| US61/217,362 | 2009-05-29 | ||
| PCT/JP2010/003620 WO2010137348A1 (en) | 2009-05-29 | 2010-05-28 | Method for selecting clone of induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012527887A JP2012527887A (ja) | 2012-11-12 |
| JP2012527887A5 true JP2012527887A5 (enExample) | 2013-08-08 |
| JP5777113B2 JP5777113B2 (ja) | 2015-09-09 |
Family
ID=43222474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012512547A Expired - Fee Related JP5777113B2 (ja) | 2009-05-29 | 2010-05-28 | 人工多能性幹細胞のクローンの選択方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9005975B2 (enExample) |
| EP (1) | EP2438159B1 (enExample) |
| JP (1) | JP5777113B2 (enExample) |
| WO (1) | WO2010137348A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2690554T3 (es) | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| EP2321406B1 (en) * | 2008-08-05 | 2014-12-10 | Keio University | Method for selecting secondary neurosphere derived from induced pluripotent stem cell |
| ES2645869T3 (es) | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| WO2011027908A1 (en) | 2009-09-02 | 2011-03-10 | Kyoto University | Method of selecting safe pluripotent stem cells |
| ES2638464T3 (es) * | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| ES2539487T3 (es) | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| AU2011235212B2 (en) | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| JP5936134B2 (ja) | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| CN107988381B (zh) | 2011-07-25 | 2021-05-28 | 国立大学法人京都大学 | 筛选诱导的多能干细胞的方法 |
| EP3095864B1 (en) * | 2014-01-14 | 2020-04-15 | Kagoshima University | Method for labelling cancerization-causing cell in stem cells |
| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| AU2016338680B2 (en) | 2015-10-16 | 2022-11-17 | Fate Therapeutics, Inc. | Platform for the induction and maintenance of ground state pluripotency |
| KR101783977B1 (ko) | 2016-12-30 | 2017-10-10 | 제일약품주식회사 | 기형종 형성이 억제된 전분화능 줄기세포 유래 신경 전구체구의 제조 방법 |
| WO2018232079A1 (en) | 2017-06-14 | 2018-12-20 | Daley George Q | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
| MX2022008648A (es) | 2020-01-23 | 2022-12-15 | The Children´S Medical Center Corp | Diferenciacion de celulas t sin estroma a partir de celulas madre pluripotentes humanas. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3660601B2 (ja) | 2001-03-30 | 2005-06-15 | 独立行政法人科学技術振興機構 | 胚性幹細胞からの神経幹細胞、運動ニューロン及びgaba作動性ニューロンの製造法 |
| AUPS225402A0 (en) | 2002-05-10 | 2002-06-13 | Bresagen Limited | Modified cell production |
| US7964401B2 (en) | 2004-02-19 | 2011-06-21 | Kyoto University | Screening method for somatic cell nuclear reprogramming substance affecting ECAT2 and ECAT3 |
| AU2006304390A1 (en) | 2005-10-17 | 2007-04-26 | Academia Sinica | Pulmonary stem cells, related methods and kits |
| US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US8129187B2 (en) * | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
| KR101420740B1 (ko) | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| KR100794362B1 (ko) | 2006-02-27 | 2008-01-15 | 주식회사 임젠 | Nanog를 이용한 아스트로사이트의 신경줄기세포로의역분화 |
| EP2137296A2 (en) | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| KR101564044B1 (ko) | 2007-10-31 | 2015-10-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 핵초기화 방법 |
| EP2072618A1 (en) * | 2007-12-14 | 2009-06-24 | Johannes Gutenberg-Universität Mainz | Use of RNA for reprogramming somatic cells |
| ES2690554T3 (es) | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| EP2321406B1 (en) | 2008-08-05 | 2014-12-10 | Keio University | Method for selecting secondary neurosphere derived from induced pluripotent stem cell |
| JP5936134B2 (ja) | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
-
2010
- 2010-05-28 EP EP10780308.2A patent/EP2438159B1/en not_active Not-in-force
- 2010-05-28 WO PCT/JP2010/003620 patent/WO2010137348A1/en not_active Ceased
- 2010-05-28 JP JP2012512547A patent/JP5777113B2/ja not_active Expired - Fee Related
- 2010-05-28 US US13/375,099 patent/US9005975B2/en not_active Expired - Fee Related
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