JP2012526848A5 - - Google Patents

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Publication number
JP2012526848A5
JP2012526848A5 JP2012511019A JP2012511019A JP2012526848A5 JP 2012526848 A5 JP2012526848 A5 JP 2012526848A5 JP 2012511019 A JP2012511019 A JP 2012511019A JP 2012511019 A JP2012511019 A JP 2012511019A JP 2012526848 A5 JP2012526848 A5 JP 2012526848A5
Authority
JP
Japan
Prior art keywords
ranolazine
composition
nervous system
central nervous
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012511019A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012526848A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/034778 external-priority patent/WO2010132696A1/en
Publication of JP2012526848A publication Critical patent/JP2012526848A/ja
Publication of JP2012526848A5 publication Critical patent/JP2012526848A5/ja
Pending legal-status Critical Current

Links

JP2012511019A 2009-05-14 2010-05-13 Cns障害の治療のためのラノラジン Pending JP2012526848A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17817009P 2009-05-14 2009-05-14
US61/178,170 2009-05-14
US27939509P 2009-10-20 2009-10-20
US61/279,395 2009-10-20
PCT/US2010/034778 WO2010132696A1 (en) 2009-05-14 2010-05-13 Ranolazine for the treatment of cns disorders

Publications (2)

Publication Number Publication Date
JP2012526848A JP2012526848A (ja) 2012-11-01
JP2012526848A5 true JP2012526848A5 (enExample) 2013-06-27

Family

ID=42262042

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012511019A Pending JP2012526848A (ja) 2009-05-14 2010-05-13 Cns障害の治療のためのラノラジン

Country Status (7)

Country Link
US (1) US20100292217A1 (enExample)
EP (1) EP2429526A1 (enExample)
JP (1) JP2012526848A (enExample)
AU (1) AU2010248948A1 (enExample)
CA (1) CA2761771A1 (enExample)
MX (1) MX2011012140A (enExample)
WO (1) WO2010132696A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100551370C (zh) * 2002-05-21 2009-10-21 Cv医药有限公司 雷诺嗪在制备治疗糖尿病的药物组合物中的应用
CN101896181A (zh) * 2007-05-31 2010-11-24 吉利德帕洛阿尔托股份有限公司 用于升高的脑钠肽的雷诺嗪
US20090247535A1 (en) * 2008-03-26 2009-10-01 Duke University Use of ranolazine for non-cardiovascular disorders
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
CN113318111B (zh) * 2021-06-21 2026-02-03 浙江大学 Nav1.1激动剂在制备治疗自闭症的药物中的应用
WO2025078664A1 (en) * 2023-10-12 2025-04-17 Celex Oncology Innovations Limited Treatment of metastatic or invasive brain cancer

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US4173626A (en) * 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
US4326525A (en) * 1980-10-14 1982-04-27 Alza Corporation Osmotic device that improves delivery properties of agent in situ
US5364620A (en) * 1983-12-22 1994-11-15 Elan Corporation, Plc Controlled absorption diltiazem formulation for once daily administration
US5023252A (en) * 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5001139A (en) * 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
US4992445A (en) * 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
US4902514A (en) * 1988-07-21 1990-02-20 Alza Corporation Dosage form for administering nilvadipine for treating cardiovascular symptoms
DK0407780T3 (da) * 1989-06-23 1996-09-30 Syntex Inc Ranolazin og beslægtede piperaziner til anvendelse i behandling af væv, der har været udsat for fysisk eller kemisk skade
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
CA2172513C (en) * 1993-09-24 2008-01-08 Bernard A. Macleod Aminocyclohexylesters and uses thereof
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US6541479B1 (en) * 1997-12-02 2003-04-01 Massachusetts College Of Pharmacy Calcium channel blockers
US6479496B1 (en) * 1998-09-10 2002-11-12 Cv Therapeutics, Inc. Methods for treating angina with ranolazine
US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
EP1259230A2 (en) * 2000-02-18 2002-11-27 Cv Therapeutics, Inc. Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure
US6677336B2 (en) * 2000-02-22 2004-01-13 Cv Therapeutics, Inc. Substituted piperazine compounds
CN103356996A (zh) * 2000-05-19 2013-10-23 埃米林药品公司 Glp-1用于制备治疗急性冠脉综合征的药物的用途
US20020052377A1 (en) * 2000-07-21 2002-05-02 Wolff Andrew A. Method for treating angina
US6573264B1 (en) * 2000-10-23 2003-06-03 Cv Therapeutics, Inc. Heteroaryl alkyl piperazine derivatives
DK1406898T3 (da) * 2001-07-19 2005-05-30 Cv Therapeutics Inc Substituerede piperazinforbindelser og anvendelse af disse som fedtsyreoxidationsinhibitorer
US20080109040A1 (en) * 2002-04-04 2008-05-08 Luiz Belardinelli Method of treating arrhythmias
US20030220344A1 (en) * 2002-04-04 2003-11-27 Luiz Belardinelli Method of treating arrhythmias
CN100551370C (zh) * 2002-05-21 2009-10-21 Cv医药有限公司 雷诺嗪在制备治疗糖尿病的药物组合物中的应用
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
MX2007005367A (es) * 2004-11-09 2007-06-18 Cv Therapeutics Inc Uso de ranolazina en combinacion con por lo menos un agente de remodelacion para revertir la remodelacion ventricular izquierda en el tratamiento de la insuficiencia cardiaca.
JP2008526879A (ja) * 2005-01-06 2008-07-24 シーブイ・セラピューティクス・インコーポレイテッド ラノラジンを含有する徐放性薬学的処方物
JP2010518170A (ja) * 2007-02-13 2010-05-27 ギリアード・パロ・アルト・インコーポレイテッド 冠微小血管疾患の処置のためのラノラジンの使用
US20090312340A1 (en) * 2007-02-13 2009-12-17 Whedy Wang Use of ranolazine for the treatment of cardiovascular diseases
CA2678515A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of cardiovascular diseases
CA2678325A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of non-coronary microvascular diseases
US20090111826A1 (en) * 2007-02-13 2009-04-30 Louis Lange Use of ranolazine for the treatment of cardiovascular diseases
WO2008116083A1 (en) * 2007-03-22 2008-09-25 Cv Therapeutics, Inc. Use of ranolazine for elevated brain-type natriuretic peptide
CN101896181A (zh) * 2007-05-31 2010-11-24 吉利德帕洛阿尔托股份有限公司 用于升高的脑钠肽的雷诺嗪
KR20110013348A (ko) * 2008-02-06 2011-02-09 길리애드 사이언시즈, 인코포레이티드 통증 치료를 위한 라놀라진의 용도
US20090247535A1 (en) * 2008-03-26 2009-10-01 Duke University Use of ranolazine for non-cardiovascular disorders
CA2735653A1 (en) * 2008-09-04 2010-03-11 Gilead Sciences, Inc. Method of treating atrial fibrillation
WO2010068461A1 (en) * 2008-11-25 2010-06-17 Gilead Palo Alto, Inc. Co-administration of ranolazine and cardiac glycosides

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