JP2012524902A5 - - Google Patents
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- JP2012524902A5 JP2012524902A5 JP2012507255A JP2012507255A JP2012524902A5 JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5 JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012507255 A JP2012507255 A JP 2012507255A JP 2012524902 A5 JP2012524902 A5 JP 2012524902A5
- Authority
- JP
- Japan
- Prior art keywords
- mer unit
- seq
- identity
- heterodimer
- mer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17197909P | 2009-04-23 | 2009-04-23 | |
| US61/171,979 | 2009-04-23 | ||
| PCT/US2010/030836 WO2010123720A1 (en) | 2009-04-23 | 2010-04-13 | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Division JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524902A JP2012524902A (ja) | 2012-10-18 |
| JP2012524902A5 true JP2012524902A5 (https=) | 2013-04-04 |
| JP5882196B2 JP5882196B2 (ja) | 2016-03-09 |
Family
ID=43011406
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507255A Expired - Fee Related JP5882196B2 (ja) | 2009-04-23 | 2010-04-13 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015209307A Pending JP2016035470A (ja) | 2009-04-23 | 2015-10-23 | アディポネクチン受容体フラグメントの単量体及び二量体形態ならびに使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8865648B2 (https=) |
| EP (2) | EP3444611A1 (https=) |
| JP (2) | JP5882196B2 (https=) |
| CN (1) | CN102388308B (https=) |
| ES (1) | ES2693165T3 (https=) |
| WO (1) | WO2010123720A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010123720A1 (en) | 2009-04-23 | 2010-10-28 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
| CA2735578C (en) | 2008-08-12 | 2018-10-23 | Zinfandel Pharmaceuticals, Inc. | Method of identifying risk factors for alzheimer's disease comprising tomm40 gene variants |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| EP2391377A2 (en) | 2009-02-02 | 2011-12-07 | Ramot at Tel-Aviv University Ltd. | Peptides, pharmaceutical compositions comprising same and uses thereof |
| WO2012017439A2 (en) * | 2010-08-04 | 2012-02-09 | Ramot At Tel-Aviv University Ltd. | Methods of treating autoimmune diseases of the central nervous system (cns) and neurodegenerative diseases |
| EA201391017A1 (ru) | 2011-01-10 | 2014-04-30 | Зинфандел Фармасьютикалз, Инк. | Способы и готовые лекарственные формы для лечения болезни альцгеймера |
| JP2014517911A (ja) * | 2011-04-11 | 2014-07-24 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド | アディポネクチン受容体ｃ末端フラグメント（ｃｔｆ）免疫グロブリン |
| SG11201401422VA (en) * | 2011-10-27 | 2014-09-26 | Genmab As | Production of heterodimeric proteins |
| DE102015201100B4 (de) * | 2015-01-22 | 2018-05-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Antivirale Mittel |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US20020173474A1 (en) | 1993-02-12 | 2002-11-21 | President And Fellows Of Harvard College | Methods & materials involving dimerization-mediated regulation of biological events |
| EP0700521B1 (en) | 1993-05-28 | 2003-06-04 | Baylor College Of Medicine | Method and mass spectrometer for desorption and ionization of analytes |
| SE9400088D0 (sv) | 1994-01-14 | 1994-01-14 | Kabi Pharmacia Ab | Bacterial receptor structures |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| JP3538711B2 (ja) | 1997-10-29 | 2004-06-14 | 大塚製薬株式会社 | 平滑筋増殖抑制組成物、動脈硬化症診断方法及びそのキット |
| CA2323638A1 (en) | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| WO2000056934A1 (en) | 1999-03-24 | 2000-09-28 | Packard Bioscience Company | Continuous porous matrix arrays |
| US20040067490A1 (en) | 2001-09-07 | 2004-04-08 | Mei Zhong | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| CA2382015A1 (en) | 1999-08-17 | 2001-02-22 | Incyte Genomics, Inc. | Membrane associated proteins |
| AU2001274888A1 (en) | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20020102617A1 (en) | 2000-08-03 | 2002-08-01 | Macbeath Gavin | Protein microarrays |
| EP1379554A2 (en) | 2001-02-21 | 2004-01-14 | Curagen Corporation | Proteins, polynucleotides encoding them and methods of using the same |
| US20020132773A1 (en) | 2001-03-14 | 2002-09-19 | Oklahoma Medical Research Foundation | Methods for reducing fat by administration of adiponectin |
| US20030083261A1 (en) | 2001-04-30 | 2003-05-01 | Hongtao Yu | Class of 12mer peptides that inhibit the function of the mitotic check point protein Mad2 |
| DK1426764T3 (da) | 2001-08-17 | 2011-06-27 | Fujirebio Kk | Fremgangsmåde til diagnosticering eller monitorering af fejl i sukkermetabolisme |
| WO2004022596A1 (en) | 2002-09-05 | 2004-03-18 | Komed Co., Ltd. | Monoclonal antibody against adiponectin, preparation method and use thereof |
| US20030153013A1 (en) | 2002-11-07 | 2003-08-14 | Ruo-Pan Huang | Antibody-based protein array system |
| JP4347874B2 (ja) * | 2002-12-29 | 2009-10-21 | 株式会社東京大学Ｔｌｏ | アディポネクチン受容体及びそれをコードする遺伝子 |
| EP2141235B1 (en) | 2002-12-29 | 2014-06-11 | Toudai Tlo, Ltd. | Adiponectin receptor and gene coding for the same |
| WO2004063711A2 (en) | 2003-01-09 | 2004-07-29 | Beth Israel Deaconess Medical Center, Inc. | Use of adiponectin to diagnose and treat malignancy |
| EP1607742B1 (en) | 2003-03-24 | 2011-11-23 | Mitsubishi Chemical Medience Corporation | Latex reagent for adiponectin analysis and method of adiponectin analysis |
| JP4717810B2 (ja) | 2003-06-20 | 2011-07-06 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション インコーポレイテッド | １型糖尿病と２型糖尿病を識別するためのバイオマーカー |
| US7435808B2 (en) * | 2003-06-25 | 2008-10-14 | Bristol-Myers Squibb Company | Polynucleotides encoding novel adiponectin receptor variant, AdipoR2v2 |
| ES2347562T3 (es) | 2003-09-27 | 2010-11-02 | Siemens Healthcare Diagnostics Inc. | Disagnosticos y terapias para enfermedades asociados con receptor emparejado de proteina g adipor1 (adipor1). |
| JP2007506950A (ja) | 2003-09-27 | 2007-03-22 | バイエル・ヘルスケア・エルエルシー | Ｇタンパク質共役受容体ＡｄｉｐｏＲ２（ＡｄｉｐｏＲ２）に関連する疾患の診断および治療 |
| JP4677545B2 (ja) | 2003-10-15 | 2011-04-27 | 積水メディカル株式会社 | 多量体アディポネクチンの分別測定方法 |
| EP1684807B1 (en) | 2003-11-07 | 2009-09-02 | Merck & Co., Inc. | Method of identifying responders to treatment with insulin sensitizers |
| JPWO2005084697A1 (ja) * | 2004-03-04 | 2007-11-29 | 門脇 孝 | アディポネクチン受容体発現制御剤 |
| GB0426798D0 (en) | 2004-12-07 | 2005-01-12 | Emtelle Uk Ltd | Optical fibre tube and method of manufacturing same |
| US8093017B2 (en) | 2005-12-07 | 2012-01-10 | Siemens Heathcare Diagnostics Inc. | Detection of soluble adiponectin receptor peptides and use in diagnostics and therapeutics |
| CN101932728B (zh) * | 2007-11-30 | 2013-06-19 | 西门子医疗保健诊断公司 | 脂连蛋白受体片段和使用方法 |
| WO2010123720A1 (en) | 2009-04-23 | 2010-10-28 | Siemens Healthcare Diagnostics Inc. | Monomeric and dimeric forms of adiponectin receptor fragments and methods of use |
-
2010
- 2010-04-13 WO PCT/US2010/030836 patent/WO2010123720A1/en not_active Ceased
- 2010-04-13 ES ES10767527.4T patent/ES2693165T3/es active Active
- 2010-04-13 EP EP18184946.4A patent/EP3444611A1/en not_active Withdrawn
- 2010-04-13 EP EP10767527.4A patent/EP2422199B1/en not_active Not-in-force
- 2010-04-13 JP JP2012507255A patent/JP5882196B2/ja not_active Expired - Fee Related
- 2010-04-13 US US13/265,968 patent/US8865648B2/en active Active
- 2010-04-13 CN CN201080016065.5A patent/CN102388308B/zh not_active Expired - Fee Related
-
2014
- 2014-10-20 US US14/518,749 patent/US20150038426A1/en not_active Abandoned
-
2015
- 2015-10-23 JP JP2015209307A patent/JP2016035470A/ja active Pending
-
2018
- 2018-08-09 US US16/100,176 patent/US20180346540A1/en not_active Abandoned
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