JP2002345468A5 - - Google Patents
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- Publication number
- JP2002345468A5 JP2002345468A5 JP2001123210A JP2001123210A JP2002345468A5 JP 2002345468 A5 JP2002345468 A5 JP 2002345468A5 JP 2001123210 A JP2001123210 A JP 2001123210A JP 2001123210 A JP2001123210 A JP 2001123210A JP 2002345468 A5 JP2002345468 A5 JP 2002345468A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- salt
- amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 description 41
- 229920001184 polypeptide Polymers 0.000 description 22
- 102000004196 processed proteins & peptides Human genes 0.000 description 22
- 108090000765 processed proteins & peptides Proteins 0.000 description 22
- 150000001408 amides Chemical class 0.000 description 19
- 150000002148 esters Chemical class 0.000 description 19
- 150000003839 salts Chemical class 0.000 description 19
- 229910019142 PO4 Inorganic materials 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 6
- 125000004122 cyclic group Chemical group 0.000 description 6
- 230000003834 intracellular effect Effects 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 6
- 239000010452 phosphate Substances 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 238000007792 addition Methods 0.000 description 3
- 238000012217 deletion Methods 0.000 description 3
- 230000037430 deletion Effects 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000004408 hybridoma Anatomy 0.000 description 3
- 238000006467 substitution reaction Methods 0.000 description 3
- 206010016654 Fibrosis Diseases 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000000032 diagnostic agent Substances 0.000 description 2
- 229940039227 diagnostic agent Drugs 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- -1 Amino Chemical group 0.000 description 1
- 208000017701 Endocrine disease Diseases 0.000 description 1
- 208000005764 Peripheral Arterial Disease Diseases 0.000 description 1
- 208000030831 Peripheral arterial occlusive disease Diseases 0.000 description 1
- 206010039710 Scleroderma Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 230000007882 cirrhosis Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000010120 metabolic dysregulation Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 201000002793 renal fibrosis Diseases 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000009772 tissue formation Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001123210A JP4841054B2 (ja) | 2000-04-21 | 2001-04-20 | 新規インスリン／ｉｇｆ／リラキシンファミリーポリペプチドおよびそのｄｎａ |
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000126340 | 2000-04-21 | ||
| JP2000126340 | 2000-04-21 | ||
| JP2000-126340 | 2000-04-21 | ||
| JP2000-205587 | 2000-07-03 | ||
| JP2000205587 | 2000-07-03 | ||
| JP2000205587 | 2000-07-03 | ||
| JP2000247962 | 2000-08-10 | ||
| JP2000-247962 | 2000-08-10 | ||
| JP2000247962 | 2000-08-10 | ||
| JP2000-395050 | 2000-12-22 | ||
| JP2000395050 | 2000-12-22 | ||
| JP2000395050 | 2000-12-22 | ||
| JP2001123210A JP4841054B2 (ja) | 2000-04-21 | 2001-04-20 | 新規インスリン／ｉｇｆ／リラキシンファミリーポリペプチドおよびそのｄｎａ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002345468A JP2002345468A (ja) | 2002-12-03 |
| JP2002345468A5 true JP2002345468A5 (https=) | 2008-05-29 |
| JP4841054B2 JP4841054B2 (ja) | 2011-12-21 |
Family
ID=27481250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001123210A Expired - Fee Related JP4841054B2 (ja) | 2000-04-21 | 2001-04-20 | 新規インスリン／ｉｇｆ／リラキシンファミリーポリペプチドおよびそのｄｎａ |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7049403B2 (https=) |
| EP (1) | EP1283260A4 (https=) |
| JP (1) | JP4841054B2 (https=) |
| KR (1) | KR20020093053A (https=) |
| CN (1) | CN1633498A (https=) |
| AU (2) | AU2001248809B2 (https=) |
| CA (1) | CA2406855A1 (https=) |
| WO (1) | WO2001081562A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9261901A (en) * | 2000-09-13 | 2002-03-26 | Smithkline Beecham Corp | Novel compounds |
| AUPR814401A0 (en) * | 2001-10-08 | 2001-11-01 | Howard Florey Institute Of Experimental Physiology And Medicine | Human 3 relaxin |
| JP2007524371A (ja) * | 2003-03-04 | 2007-08-30 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | レラキシン３−ｇｐｃｒ１３５複合体ならびにそれらの生産及び使用 |
| US7638490B2 (en) | 2004-02-09 | 2009-12-29 | Eisai R&D Managment Co., Ltd. | Methods of affecting feeding and weight in mammals by administration of relaxin-3 |
| EP1789452B1 (en) * | 2004-08-25 | 2012-04-25 | Janssen Pharmaceutica NV | Relaxin-chimeric polypeptides and their preparation and use |
| EP2129359B1 (en) * | 2007-01-30 | 2012-03-14 | Janssen Pharmaceutica, N.V. | Chimeric peptide antagonist for gpcr135 or gpcr142 |
| US20100161366A1 (en) * | 2008-12-19 | 2010-06-24 | Achim Clemens | Product requirement specification in production model |
| US9767495B2 (en) * | 2008-12-19 | 2017-09-19 | Sap Se | Different sales and planning product options |
| CN116773828B (zh) | 2023-08-21 | 2023-10-31 | 成都大熊猫繁育研究基地 | 一种大熊猫rln3酶联免疫检测方法及单克隆抗体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990013659A1 (en) * | 1989-05-04 | 1990-11-15 | Genentech, Inc. | Processes and compositions for the isolation of human relaxin |
| WO2000021996A2 (en) * | 1998-10-13 | 2000-04-20 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| JP2001517444A (ja) * | 1997-09-24 | 2001-10-09 | ジェネンテック・インコーポレーテッド | インスリン様ポリペプチドとその使用 |
| KR100529270B1 (ko) | 1998-12-01 | 2005-11-21 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
| WO2000047776A2 (en) * | 1999-02-12 | 2000-08-17 | Zymogenetics, Inc. | Insulin-family homolog localized to chromosome 1 |
| US20020012967A1 (en) * | 2000-03-10 | 2002-01-31 | Holloway James L. | Insulin homolog polypeptide zins4 |
| AU2001236817A1 (en) * | 2000-03-10 | 2001-09-24 | Zymogenetics Inc. | Insulin homolog polypeptide zins4 |
| AU9261901A (en) | 2000-09-13 | 2002-03-26 | Smithkline Beecham Corp | Novel compounds |
-
2001
- 2001-04-20 AU AU2001248809A patent/AU2001248809B2/en not_active Ceased
- 2001-04-20 CA CA002406855A patent/CA2406855A1/en not_active Abandoned
- 2001-04-20 JP JP2001123210A patent/JP4841054B2/ja not_active Expired - Fee Related
- 2001-04-20 CN CNA018110762A patent/CN1633498A/zh active Pending
- 2001-04-20 AU AU4880901A patent/AU4880901A/xx active Pending
- 2001-04-20 US US10/257,848 patent/US7049403B2/en not_active Expired - Fee Related
- 2001-04-20 KR KR1020027014048A patent/KR20020093053A/ko not_active Withdrawn
- 2001-04-20 WO PCT/JP2001/003399 patent/WO2001081562A1/ja not_active Ceased
- 2001-04-20 EP EP01921950A patent/EP1283260A4/en not_active Ceased
-
2005
- 2005-11-21 US US11/284,367 patent/US7410641B2/en not_active Expired - Fee Related
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