JP2012524884A5 - - Google Patents
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- Publication number
- JP2012524884A5 JP2012524884A5 JP2012503715A JP2012503715A JP2012524884A5 JP 2012524884 A5 JP2012524884 A5 JP 2012524884A5 JP 2012503715 A JP2012503715 A JP 2012503715A JP 2012503715 A JP2012503715 A JP 2012503715A JP 2012524884 A5 JP2012524884 A5 JP 2012524884A5
- Authority
- JP
- Japan
- Prior art keywords
- mmp
- positive control
- expression
- matrix metalloproteinases
- test compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013641 positive control Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 10
- 102000002274 Matrix Metalloproteinases Human genes 0.000 claims 8
- 108010000684 Matrix Metalloproteinases Proteins 0.000 claims 8
- 102100027995 Collagenase 3 Human genes 0.000 claims 5
- 108050005238 Collagenase 3 Proteins 0.000 claims 5
- 102100030412 Matrix metalloproteinase-9 Human genes 0.000 claims 5
- 108010015302 Matrix metalloproteinase-9 Proteins 0.000 claims 5
- 102100030411 Neutrophil collagenase Human genes 0.000 claims 4
- 101710118230 Neutrophil collagenase Proteins 0.000 claims 4
- 208000025157 Oral disease Diseases 0.000 claims 4
- 208000030194 mouth disease Diseases 0.000 claims 4
- 230000001105 regulatory effect Effects 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims 1
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000007565 gingivitis Diseases 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 201000001245 periodontitis Diseases 0.000 claims 1
- 229960003500 triclosan Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16568509P | 2009-04-01 | 2009-04-01 | |
| US61/165,685 | 2009-04-01 | ||
| PCT/US2010/029670 WO2010115031A1 (en) | 2009-04-01 | 2010-04-01 | Anti bone-loss and anti attachment-loss effects of an oral composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524884A JP2012524884A (ja) | 2012-10-18 |
| JP2012524884A5 true JP2012524884A5 (enExample) | 2013-07-25 |
| JP5330596B2 JP5330596B2 (ja) | 2013-10-30 |
Family
ID=42328354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012503715A Expired - Fee Related JP5330596B2 (ja) | 2009-04-01 | 2010-04-01 | 口腔用組成物の抗骨喪失および抗付着喪失作用 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8637266B2 (enExample) |
| EP (1) | EP2414838B1 (enExample) |
| JP (1) | JP5330596B2 (enExample) |
| CN (1) | CN102365550B (enExample) |
| AR (1) | AR076177A1 (enExample) |
| AU (1) | AU2010232590B2 (enExample) |
| BR (1) | BRPI1013185A2 (enExample) |
| CA (1) | CA2757317C (enExample) |
| CO (1) | CO6420374A2 (enExample) |
| DK (1) | DK2414838T3 (enExample) |
| ES (1) | ES2432864T3 (enExample) |
| MX (1) | MX2011008438A (enExample) |
| MY (1) | MY158406A (enExample) |
| PL (1) | PL2414838T3 (enExample) |
| RU (1) | RU2524629C2 (enExample) |
| SG (1) | SG173487A1 (enExample) |
| TW (1) | TWI405565B (enExample) |
| WO (1) | WO2010115031A1 (enExample) |
| ZA (1) | ZA201106054B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101745067B1 (ko) * | 2014-12-31 | 2017-06-12 | 서울대학교산학협력단 | 치주질환 예측 시스템 및 이를 이용한 치주질환 예측 방법 |
| KR102098624B1 (ko) * | 2019-09-20 | 2020-04-08 | 서울대학교산학협력단 | 타액 mmp-9 및 il-8를 이용한 치주염 예측 시스템 및 이를 이용한 치주염 예측 방법 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US4358437A (en) | 1978-11-29 | 1982-11-09 | Beecham Group Limited | Compositions |
| US5032386A (en) | 1988-12-29 | 1991-07-16 | Colgate-Palmolive Company | Antiplaque antibacterial oral composition |
| US5288480A (en) | 1987-01-30 | 1994-02-22 | Colgate-Palmolive Co. | Antiplaque antibacterial oral composition |
| US4894220A (en) | 1987-01-30 | 1990-01-16 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| GB9117140D0 (en) | 1991-08-08 | 1991-09-25 | Unilever Plc | Treatment of periodontitis |
| DE4226043A1 (de) | 1992-08-06 | 1994-02-10 | Haarmann & Reimer Gmbh | Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen |
| US5756361A (en) * | 1992-12-17 | 1998-05-26 | Metra Biosystems, Inc. | Screening method for periodontal disease |
| CA2176237A1 (en) | 1993-11-10 | 1995-05-18 | Richard P. Darveau | Treatment of bacterially-induced inflammatory diseases |
| FI98961C (fi) * | 1994-08-26 | 1997-09-10 | Medix Biochemica Ab Oy | Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi |
| US5578295A (en) | 1995-04-28 | 1996-11-26 | The Procter & Gamble Company | Oral care compositions comprising certain substituted diphenyl ethers |
| EP0935454B1 (de) | 1996-06-12 | 2001-08-22 | Cognis Deutschland GmbH | Kosmetische und/oder pharmazeutische zubereitungen |
| US5998487A (en) * | 1998-04-08 | 1999-12-07 | Colgate-Palmolive Company | Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions |
| JP3763075B2 (ja) * | 1998-04-24 | 2006-04-05 | サンスター株式会社 | 歯周病の予防又は治療用の食品組成物、口腔用組成物及び医薬組成物 |
| FR2794457B1 (fr) | 1999-06-01 | 2001-08-10 | Oreal | Derives carbonates de retinol, procede de preparation et utilisations |
| US6165447A (en) * | 1999-06-15 | 2000-12-26 | Colgate-Palmolive Company | Synergistic antibacterial combination |
| WO2001048481A1 (en) | 1999-12-03 | 2001-07-05 | Baxter International Inc. | Pyrogenicity test for use with automated immunoassay systems |
| GB0001704D0 (en) | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Protein |
| WO2001078652A2 (en) | 2000-04-14 | 2001-10-25 | Metabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US6500409B1 (en) | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
| DE10059584A1 (de) | 2000-11-30 | 2002-06-06 | Beiersdorf Ag | Kosmetische oder dermatologische getränkte Tücher |
| DOP2002000332A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| AU2003249531A1 (en) * | 2002-08-13 | 2004-02-25 | Warner-Lambert Company Llc | Azaisoquinoline derivatives as matrix metalloproteinase inhibitors |
| US7005225B2 (en) | 2002-11-12 | 2006-02-28 | Samsung Electronics Company | Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications |
| TW200902047A (en) | 2003-02-14 | 2009-01-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| GB2401865A (en) | 2003-05-22 | 2004-11-24 | Givaudan Sa | Antibacterial and antifungal glycerol monocarbonates |
| WO2005039504A2 (en) | 2003-10-24 | 2005-05-06 | Eisai Co., Ltd. | Compounds and methods for treating toll-like receptor 2-related diseases and conditions |
| US20070212686A1 (en) | 2003-12-03 | 2007-09-13 | Whitehead Institute For Biomedical Research | Use Of T-Cadherin As A Target |
| FI20040572A0 (fi) * | 2004-04-23 | 2004-04-23 | Ctt Cancer Targeting Tech Oy | Matriisi-metalloproteinaasin aktiviteetin inhibiittorit |
| JP4662043B2 (ja) * | 2004-09-09 | 2011-03-30 | 国立大学法人東京農工大学 | 歯周病発症の評価システム |
| CN101111288A (zh) * | 2004-12-02 | 2008-01-23 | 高露洁-棕榄公司 | 含酚类化合物和抗氧化剂维生素和维生素衍生物的口腔护理组合物 |
| US20060141421A1 (en) | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | System and method for detecting substances related to oral health |
| WO2006074450A2 (en) | 2005-01-07 | 2006-07-13 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases |
| JP5024506B2 (ja) * | 2005-03-25 | 2012-09-12 | ライオン株式会社 | 歯周組織破壊の抑制・改善剤及び口腔用組成物 |
| RU2431845C2 (ru) | 2006-01-10 | 2011-10-20 | Колгейт-Палмолив Компани | Способы модулирования рецепторов клеточных поверхностей для предотвращения или снижения воспаления |
| US20080161394A1 (en) | 2006-11-23 | 2008-07-03 | Jean-Yves Fouron | Cosmetic composition comprising at least one volatile carbonic acid ester |
| WO2008093072A2 (en) | 2007-01-29 | 2008-08-07 | Paul Webb | Topical composition against contact dermatitis due to water |
| US8333981B2 (en) | 2007-10-09 | 2012-12-18 | Humco Holding Group, Inc. | Antifungal treatment of nails |
| TWI481870B (zh) * | 2009-04-01 | 2015-04-21 | Colgate Palmolive Co | 用於軟組織疾病診斷及作為用於口腔保健干預的標靶之蛋白質生物標記 |
-
2010
- 2010-03-31 TW TW099109773A patent/TWI405565B/zh not_active IP Right Cessation
- 2010-03-31 AR ARP100101094A patent/AR076177A1/es unknown
- 2010-04-01 JP JP2012503715A patent/JP5330596B2/ja not_active Expired - Fee Related
- 2010-04-01 WO PCT/US2010/029670 patent/WO2010115031A1/en not_active Ceased
- 2010-04-01 EP EP10712854.8A patent/EP2414838B1/en not_active Revoked
- 2010-04-01 DK DK10712854.8T patent/DK2414838T3/da active
- 2010-04-01 CN CN201080015649.0A patent/CN102365550B/zh not_active Expired - Fee Related
- 2010-04-01 ES ES10712854T patent/ES2432864T3/es active Active
- 2010-04-01 AU AU2010232590A patent/AU2010232590B2/en not_active Ceased
- 2010-04-01 RU RU2011144028/15A patent/RU2524629C2/ru not_active IP Right Cessation
- 2010-04-01 BR BRPI1013185A patent/BRPI1013185A2/pt not_active IP Right Cessation
- 2010-04-01 MX MX2011008438A patent/MX2011008438A/es active IP Right Grant
- 2010-04-01 CA CA2757317A patent/CA2757317C/en not_active Expired - Fee Related
- 2010-04-01 PL PL10712854T patent/PL2414838T3/pl unknown
- 2010-04-01 US US13/262,027 patent/US8637266B2/en active Active
- 2010-04-01 MY MYPI2011003577A patent/MY158406A/en unknown
- 2010-04-01 SG SG2011055332A patent/SG173487A1/en unknown
-
2011
- 2011-08-17 ZA ZA2011/06054A patent/ZA201106054B/en unknown
- 2011-09-06 CO CO11114807A patent/CO6420374A2/es not_active Application Discontinuation
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