CN102365550B - 口腔组合物的抗骨丢失和抗附着丧失作用 - Google Patents

口腔组合物的抗骨丢失和抗附着丧失作用 Download PDF

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Publication number
CN102365550B
CN102365550B CN201080015649.0A CN201080015649A CN102365550B CN 102365550 B CN102365550 B CN 102365550B CN 201080015649 A CN201080015649 A CN 201080015649A CN 102365550 B CN102365550 B CN 102365550B
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China
Prior art keywords
mmp
positive control
periodontitis
expression
oral
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Expired - Fee Related
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CN201080015649.0A
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English (en)
Chinese (zh)
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CN102365550A (zh
Inventor
V·巴恩斯
H·M·特里维迪
王炜
徐韬
清水映美
N·C·帕特里奇
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Colgate Palmolive Co
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Colgate Palmolive Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56955—Bacteria involved in periodontal diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201080015649.0A 2009-04-01 2010-04-01 口腔组合物的抗骨丢失和抗附着丧失作用 Expired - Fee Related CN102365550B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16568509P 2009-04-01 2009-04-01
US61/165685 2009-04-01
PCT/US2010/029670 WO2010115031A1 (en) 2009-04-01 2010-04-01 Anti bone-loss and anti attachment-loss effects of an oral composition

Publications (2)

Publication Number Publication Date
CN102365550A CN102365550A (zh) 2012-02-29
CN102365550B true CN102365550B (zh) 2014-08-13

Family

ID=42328354

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CN201080015649.0A Expired - Fee Related CN102365550B (zh) 2009-04-01 2010-04-01 口腔组合物的抗骨丢失和抗附着丧失作用

Country Status (19)

Country Link
US (1) US8637266B2 (enExample)
EP (1) EP2414838B1 (enExample)
JP (1) JP5330596B2 (enExample)
CN (1) CN102365550B (enExample)
AR (1) AR076177A1 (enExample)
AU (1) AU2010232590B2 (enExample)
BR (1) BRPI1013185A2 (enExample)
CA (1) CA2757317C (enExample)
CO (1) CO6420374A2 (enExample)
DK (1) DK2414838T3 (enExample)
ES (1) ES2432864T3 (enExample)
MX (1) MX2011008438A (enExample)
MY (1) MY158406A (enExample)
PL (1) PL2414838T3 (enExample)
RU (1) RU2524629C2 (enExample)
SG (1) SG173487A1 (enExample)
TW (1) TWI405565B (enExample)
WO (1) WO2010115031A1 (enExample)
ZA (1) ZA201106054B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101745067B1 (ko) * 2014-12-31 2017-06-12 서울대학교산학협력단 치주질환 예측 시스템 및 이를 이용한 치주질환 예측 방법
KR102098624B1 (ko) * 2019-09-20 2020-04-08 서울대학교산학협력단 타액 mmp-9 및 il-8를 이용한 치주염 예측 시스템 및 이를 이용한 치주염 예측 방법

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DE4226043A1 (de) 1992-08-06 1994-02-10 Haarmann & Reimer Gmbh Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen
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US5578295A (en) 1995-04-28 1996-11-26 The Procter & Gamble Company Oral care compositions comprising certain substituted diphenyl ethers
EP0935454B1 (de) 1996-06-12 2001-08-22 Cognis Deutschland GmbH Kosmetische und/oder pharmazeutische zubereitungen
US5998487A (en) * 1998-04-08 1999-12-07 Colgate-Palmolive Company Anti-inflammatory and antibacterial benzyl phenol agents and their use in oral compositions
JP3763075B2 (ja) * 1998-04-24 2006-04-05 サンスター株式会社 歯周病の予防又は治療用の食品組成物、口腔用組成物及び医薬組成物
FR2794457B1 (fr) 1999-06-01 2001-08-10 Oreal Derives carbonates de retinol, procede de preparation et utilisations
US6165447A (en) * 1999-06-15 2000-12-26 Colgate-Palmolive Company Synergistic antibacterial combination
WO2001048481A1 (en) 1999-12-03 2001-07-05 Baxter International Inc. Pyrogenicity test for use with automated immunoassay systems
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WO2001078652A2 (en) 2000-04-14 2001-10-25 Metabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
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US6500409B1 (en) 2000-05-10 2002-12-31 Colgate Palmolive Company Synergistic antiplaque/antigingivitis oral composition
DE10059584A1 (de) 2000-11-30 2002-06-06 Beiersdorf Ag Kosmetische oder dermatologische getränkte Tücher
DOP2002000332A (es) * 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz
AU2003249531A1 (en) * 2002-08-13 2004-02-25 Warner-Lambert Company Llc Azaisoquinoline derivatives as matrix metalloproteinase inhibitors
US7005225B2 (en) 2002-11-12 2006-02-28 Samsung Electronics Company Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications
TW200902047A (en) 2003-02-14 2009-01-16 Combinatorx Inc Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
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JP4662043B2 (ja) * 2004-09-09 2011-03-30 国立大学法人東京農工大学 歯周病発症の評価システム
CN101111288A (zh) * 2004-12-02 2008-01-23 高露洁-棕榄公司 含酚类化合物和抗氧化剂维生素和维生素衍生物的口腔护理组合物
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Also Published As

Publication number Publication date
TW201039812A (en) 2010-11-16
MY158406A (en) 2016-10-14
CN102365550A (zh) 2012-02-29
PL2414838T3 (pl) 2014-01-31
EP2414838A1 (en) 2012-02-08
RU2011144028A (ru) 2013-05-10
AR076177A1 (es) 2011-05-26
US20120107843A1 (en) 2012-05-03
AU2010232590A1 (en) 2011-08-18
WO2010115031A1 (en) 2010-10-07
DK2414838T3 (da) 2013-11-04
EP2414838B1 (en) 2013-08-28
JP2012524884A (ja) 2012-10-18
CA2757317C (en) 2014-03-11
CA2757317A1 (en) 2010-10-07
HK1167272A1 (en) 2012-11-23
BRPI1013185A2 (pt) 2016-04-12
CO6420374A2 (es) 2012-04-16
TWI405565B (zh) 2013-08-21
ZA201106054B (en) 2014-01-29
JP5330596B2 (ja) 2013-10-30
SG173487A1 (en) 2011-09-29
RU2524629C2 (ru) 2014-07-27
MX2011008438A (es) 2011-09-06
ES2432864T3 (es) 2013-12-05
AU2010232590B2 (en) 2013-03-07
US8637266B2 (en) 2014-01-28

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Granted publication date: 20140813