JP2012524766A5 - - Google Patents
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- Publication number
- JP2012524766A5 JP2012524766A5 JP2012506551A JP2012506551A JP2012524766A5 JP 2012524766 A5 JP2012524766 A5 JP 2012524766A5 JP 2012506551 A JP2012506551 A JP 2012506551A JP 2012506551 A JP2012506551 A JP 2012506551A JP 2012524766 A5 JP2012524766 A5 JP 2012524766A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- hydrogen
- cyano
- atom
- halogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR09/01995 | 2009-04-24 | ||
| FR0901995A FR2944792B1 (fr) | 2009-04-24 | 2009-04-24 | Derives de 1h-pyrazolo[4,3-c]isoquinoleines, leur preparation et leur application en therapeutique |
| PCT/FR2010/050773 WO2010122272A1 (fr) | 2009-04-24 | 2010-04-22 | DERIVES DE 1-PYRAZOLO[4,3-c]ISOQUINOLEINES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524766A JP2012524766A (ja) | 2012-10-18 |
| JP2012524766A5 true JP2012524766A5 (enExample) | 2014-12-18 |
| JP5722880B2 JP5722880B2 (ja) | 2015-05-27 |
Family
ID=41259738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012506551A Expired - Fee Related JP5722880B2 (ja) | 2009-04-24 | 2010-04-22 | １Ｈ−ピラゾロ［４，３−ｃ］イソキノリン誘導体、これらの調製およびこれらの治療上の使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8461175B2 (enExample) |
| EP (1) | EP2421864B1 (enExample) |
| JP (1) | JP5722880B2 (enExample) |
| KR (1) | KR101675609B1 (enExample) |
| CN (1) | CN102459260B (enExample) |
| AR (1) | AR076393A1 (enExample) |
| AU (1) | AU2010240742B2 (enExample) |
| BR (1) | BRPI1013724A2 (enExample) |
| CA (1) | CA2791947A1 (enExample) |
| CY (1) | CY1115678T1 (enExample) |
| DK (1) | DK2421864T3 (enExample) |
| ES (1) | ES2515240T3 (enExample) |
| FR (1) | FR2944792B1 (enExample) |
| HR (1) | HRP20141058T1 (enExample) |
| IL (1) | IL215733A (enExample) |
| MX (1) | MX2011011246A (enExample) |
| MY (1) | MY156362A (enExample) |
| PL (1) | PL2421864T3 (enExample) |
| PT (1) | PT2421864E (enExample) |
| RU (1) | RU2530775C2 (enExample) |
| SG (1) | SG175338A1 (enExample) |
| SI (1) | SI2421864T1 (enExample) |
| TW (1) | TWI468405B (enExample) |
| UY (1) | UY32575A (enExample) |
| WO (1) | WO2010122272A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109020972B (zh) * | 2018-10-08 | 2021-03-09 | 广东石油化工学院 | 一种三唑并[1，5-a]喹啉衍生物的制备方法 |
| WO2023039510A1 (en) * | 2021-09-10 | 2023-03-16 | The Trustees Of Columbia University In The City Of New York | Gpx4 inhibitors and uses thereof |
| CN116535356A (zh) * | 2023-03-06 | 2023-08-04 | 中国药科大学 | 3-氨基-5-苯基-吡唑类衍生物微管蛋白抑制剂及其制备和医药用途 |
| EP4506003A1 (en) | 2023-08-07 | 2025-02-12 | S.Yu Yunusov Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan | Halogen derivatives of (4´,5´- methylenedioxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline for use in the treatment of leukemia |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8600752D0 (en) * | 1986-01-14 | 1986-02-19 | Roussel Lab Ltd | Chemical compounds |
| DE10229762A1 (de) * | 2002-07-03 | 2004-01-22 | Aventis Pharma Deutschland Gmbh | Pyrazoloisoquinolinenderivaten zur Inhibierung von NFkappaB-induzierende Kinase |
| MXPA05013485A (es) * | 2003-07-03 | 2006-04-05 | Aventis Pharma Inc | Derivados de pirazoloisoquinolina como inhibidores de cinasa. |
| US7132428B2 (en) * | 2003-07-03 | 2006-11-07 | Aventis Pharmaceuticals Inc. | Pyrazoloisoquinoline derivative as kinase inhibitors for the treatment of various disorders |
| US7872014B2 (en) * | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| AR058223A1 (es) * | 2005-11-25 | 2008-01-23 | Palau Pharma Sa | Un comuesto de derivados de pirazoloisoquinolina, un procedimiento para l a preparacion de dicho compuesto y una composicion farmaceutica que comprende dicho compuesto |
-
2009
- 2009-04-24 FR FR0901995A patent/FR2944792B1/fr not_active Expired - Fee Related
-
2010
- 2010-04-22 AU AU2010240742A patent/AU2010240742B2/en not_active Ceased
- 2010-04-22 EP EP10723723.2A patent/EP2421864B1/fr active Active
- 2010-04-22 CN CN201080028355.1A patent/CN102459260B/zh not_active Expired - Fee Related
- 2010-04-22 WO PCT/FR2010/050773 patent/WO2010122272A1/fr not_active Ceased
- 2010-04-22 ES ES10723723.2T patent/ES2515240T3/es active Active
- 2010-04-22 CA CA2791947A patent/CA2791947A1/fr not_active Abandoned
- 2010-04-22 MY MYPI2011005108A patent/MY156362A/en unknown
- 2010-04-22 SG SG2011077963A patent/SG175338A1/en unknown
- 2010-04-22 RU RU2011147658/04A patent/RU2530775C2/ru not_active IP Right Cessation
- 2010-04-22 US US13/265,981 patent/US8461175B2/en not_active Expired - Fee Related
- 2010-04-22 PT PT107237232T patent/PT2421864E/pt unknown
- 2010-04-22 DK DK10723723.2T patent/DK2421864T3/da active
- 2010-04-22 JP JP2012506551A patent/JP5722880B2/ja not_active Expired - Fee Related
- 2010-04-22 BR BRPI1013724A patent/BRPI1013724A2/pt not_active IP Right Cessation
- 2010-04-22 KR KR1020117027900A patent/KR101675609B1/ko not_active Expired - Fee Related
- 2010-04-22 HR HRP20141058AT patent/HRP20141058T1/hr unknown
- 2010-04-22 SI SI201030757T patent/SI2421864T1/sl unknown
- 2010-04-22 PL PL10723723T patent/PL2421864T3/pl unknown
- 2010-04-22 MX MX2011011246A patent/MX2011011246A/es active IP Right Grant
- 2010-04-23 TW TW99112914A patent/TWI468405B/zh not_active IP Right Cessation
- 2010-04-23 AR ARP100101357A patent/AR076393A1/es unknown
- 2010-04-23 UY UY0001032575A patent/UY32575A/es not_active Application Discontinuation
-
2011
- 2011-10-11 IL IL215733A patent/IL215733A/en not_active IP Right Cessation
-
2014
- 2014-10-30 CY CY20141100897T patent/CY1115678T1/el unknown
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