JP2012522756A5 - - Google Patents

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Publication number
JP2012522756A5
JP2012522756A5 JP2012502710A JP2012502710A JP2012522756A5 JP 2012522756 A5 JP2012522756 A5 JP 2012522756A5 JP 2012502710 A JP2012502710 A JP 2012502710A JP 2012502710 A JP2012502710 A JP 2012502710A JP 2012522756 A5 JP2012522756 A5 JP 2012522756A5
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JP
Japan
Prior art keywords
cancer
lif
inhibitor
gene
glioma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012502710A
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English (en)
Japanese (ja)
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JP2012522756A (ja
JP6207836B2 (ja
Filing date
Publication date
Priority claimed from ES200900928A external-priority patent/ES2363358B1/es
Application filed filed Critical
Publication of JP2012522756A publication Critical patent/JP2012522756A/ja
Publication of JP2012522756A5 publication Critical patent/JP2012522756A5/ja
Application granted granted Critical
Publication of JP6207836B2 publication Critical patent/JP6207836B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012502710A 2009-04-03 2010-04-06 望ましくない細胞増殖と関連する疾患の治療のための治療剤 Expired - Fee Related JP6207836B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200900928 2009-04-03
ES200900928A ES2363358B1 (es) 2009-04-03 2009-04-03 Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
PCT/EP2010/054499 WO2010115868A2 (en) 2009-04-03 2010-04-06 Therapeutic agents for the treatment of diseases associated with undesired cell proliferation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015178986A Division JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Publications (3)

Publication Number Publication Date
JP2012522756A JP2012522756A (ja) 2012-09-27
JP2012522756A5 true JP2012522756A5 (enExample) 2013-05-23
JP6207836B2 JP6207836B2 (ja) 2017-10-04

Family

ID=42342718

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2012502710A Expired - Fee Related JP6207836B2 (ja) 2009-04-03 2010-04-06 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2015178986A Pending JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2018152551A Pending JP2019006784A (ja) 2009-04-03 2018-08-14 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2020016672A Pending JP2020090522A (ja) 2009-04-03 2020-02-04 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2021186785A Active JP7197665B2 (ja) 2009-04-03 2021-11-17 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2015178986A Pending JP2016040255A (ja) 2009-04-03 2015-09-11 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2018152551A Pending JP2019006784A (ja) 2009-04-03 2018-08-14 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2020016672A Pending JP2020090522A (ja) 2009-04-03 2020-02-04 望ましくない細胞増殖と関連する疾患の治療のための治療剤
JP2021186785A Active JP7197665B2 (ja) 2009-04-03 2021-11-17 望ましくない細胞増殖と関連する疾患の治療のための治療剤

Country Status (24)

Country Link
US (4) US10100112B2 (enExample)
EP (2) EP3045474B1 (enExample)
JP (5) JP6207836B2 (enExample)
KR (6) KR20220035978A (enExample)
CN (2) CN107964043A (enExample)
AU (1) AU2010233791B2 (enExample)
BR (1) BRPI1015369A2 (enExample)
CA (1) CA2757680C (enExample)
CY (1) CY1124148T1 (enExample)
DK (1) DK3045474T3 (enExample)
EA (1) EA201101450A1 (enExample)
ES (2) ES2363358B1 (enExample)
HR (1) HRP20210352T1 (enExample)
HU (1) HUE054196T2 (enExample)
IL (1) IL215467A (enExample)
LT (1) LT3045474T (enExample)
MX (1) MX336903B (enExample)
PL (1) PL3045474T3 (enExample)
PT (1) PT3045474T (enExample)
SG (2) SG175032A1 (enExample)
SI (1) SI3045474T1 (enExample)
SM (1) SMT202100153T1 (enExample)
WO (1) WO2010115868A2 (enExample)
ZA (1) ZA201107215B (enExample)

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EP2371860A1 (en) 2010-04-05 2011-10-05 Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation
JP2015071566A (ja) * 2013-10-03 2015-04-16 住友ベークライト株式会社 Fgf4遺伝子増幅腫瘍の医薬組成物
EP3116867A4 (en) * 2014-03-11 2017-10-18 Godavari Biorefineries Ltd. Cancer stem cell targeting compounds
CA2953816C (en) * 2014-06-30 2022-03-15 Altor Bioscience Corporation Il-15-based molecules and methods of use thereof
AU2015314980A1 (en) * 2014-09-10 2017-03-02 The Regents Of The University Of California Targeting K-Ras-mediated signaling pathways and malignancy by anti-hLIF antibodies
EP3067422B1 (en) * 2015-03-13 2024-07-31 Sabanci Üniversitesi Ct-1 inhibitors
EP3273983B1 (en) 2015-03-23 2021-05-05 Evestra, Inc. Novel cytotoxic agents that preferentially target leukemia inhibitory factor (lif) for the treatment of malignancies and as new contraceptive agents
EP3173483A1 (en) 2015-11-27 2017-05-31 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Agents for the treatment of diseases associated with undesired cell proliferation
EP4321219A3 (en) 2016-12-19 2024-05-15 Medimmune Limited Antibodies against lif and uses thereof
US10583191B2 (en) 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
EP3794031A2 (en) * 2018-05-14 2021-03-24 MedImmune Limited Antibodies against lif and dosage forms thereof
US20210253691A1 (en) * 2018-06-18 2021-08-19 Medimmune Limited Methods for improving response to anti-lif antibody treatment in individuals with cancer
JP7379390B2 (ja) * 2018-06-18 2023-11-14 メドイミューン・リミテッド 癌の治療に使用するためのlif阻害剤と白金系抗悪性腫瘍剤の組み合わせ
WO2020056349A2 (en) * 2018-09-13 2020-03-19 Evestra, Inc. Lif/lifr antagonist oncology and nonmalignant diseases
AU2020259884A1 (en) * 2019-04-17 2021-10-07 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
CN111020030A (zh) * 2019-12-03 2020-04-17 中山大学 一种骨肉瘤干细胞标志物及其应用、试剂盒
EP3988116A1 (en) * 2020-10-23 2022-04-27 Consejo Superior De Investigaciones Científicas (CSIC) Methods and compositions for the treatment of hematologic malignancies
CN120507517B (zh) * 2025-05-21 2026-04-10 浙江省肿瘤医院 用于评估宫颈癌鳞癌和腺癌特异性的预后分子标记物及其应用

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US10583191B2 (en) * 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof

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