JP2012520446A5 - - Google Patents

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Publication number
JP2012520446A5
JP2012520446A5 JP2011553450A JP2011553450A JP2012520446A5 JP 2012520446 A5 JP2012520446 A5 JP 2012520446A5 JP 2011553450 A JP2011553450 A JP 2011553450A JP 2011553450 A JP2011553450 A JP 2011553450A JP 2012520446 A5 JP2012520446 A5 JP 2012520446A5
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JP
Japan
Prior art keywords
monitoring
biomarker
cells
methyl
dim
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JP2011553450A
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English (en)
Japanese (ja)
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JP5667581B2 (ja
JP2012520446A (ja
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Priority claimed from PCT/EP2010/053063 external-priority patent/WO2010103058A1/en
Publication of JP2012520446A publication Critical patent/JP2012520446A/ja
Publication of JP2012520446A5 publication Critical patent/JP2012520446A5/ja
Application granted granted Critical
Publication of JP5667581B2 publication Critical patent/JP5667581B2/ja
Expired - Fee Related legal-status Critical Current
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JP2011553450A 2009-03-12 2010-03-11 治療をモニターするためのバイオマーカーを使用した方法またはシステム Expired - Fee Related JP5667581B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09154964 2009-03-12
EP09154964.2 2009-03-12
PCT/EP2010/053063 WO2010103058A1 (en) 2009-03-12 2010-03-11 Method or system using biomarkers for the monitoring of a treatment

Publications (3)

Publication Number Publication Date
JP2012520446A JP2012520446A (ja) 2012-09-06
JP2012520446A5 true JP2012520446A5 (https=) 2013-04-25
JP5667581B2 JP5667581B2 (ja) 2015-02-12

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ID=42129920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011553450A Expired - Fee Related JP5667581B2 (ja) 2009-03-12 2010-03-11 治療をモニターするためのバイオマーカーを使用した方法またはシステム

Country Status (24)

Country Link
US (1) US8802384B2 (https=)
EP (1) EP2406628A1 (https=)
JP (1) JP5667581B2 (https=)
KR (1) KR20110137307A (https=)
CN (1) CN102334030A (https=)
AR (1) AR076113A1 (https=)
AU (1) AU2010223256B2 (https=)
BR (1) BRPI1011688A2 (https=)
CA (1) CA2755055A1 (https=)
CL (1) CL2011002260A1 (https=)
CO (1) CO6430497A2 (https=)
EA (1) EA201101300A1 (https=)
EC (1) ECSP11011323A (https=)
IL (1) IL214747A0 (https=)
MA (1) MA33120B1 (https=)
MX (1) MX2011009482A (https=)
NZ (1) NZ594843A (https=)
PE (1) PE20120592A1 (https=)
SG (1) SG174324A1 (https=)
TN (1) TN2011000457A1 (https=)
TW (1) TW201100802A (https=)
UA (1) UA107789C2 (https=)
UY (1) UY32482A (https=)
WO (1) WO2010103058A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA107560C2 (uk) * 2008-06-06 2015-01-26 Фармацевтична лікарська форма для негайного вивільнення похідної індолінону
MX2010013203A (es) * 2008-06-06 2011-02-25 Boehringer Ingelheim Int Forma de dosificacion farmaceutica en capsula que comprende una formulacion en suspension de un derivado de indolinona.
US20170065529A1 (en) 2015-09-09 2017-03-09 Boehringer Ingelheim International Gmbh Pharmaceutical dosage form for immediate release of an indolinone derivative
US20140350022A1 (en) 2013-05-10 2014-11-27 Boehringer Ingelheim International Gmbh Efficacious treatment of NSCLC and predictive clinical marker of the responsiveness of a tumour to a treatment
CN104003925B (zh) * 2013-06-05 2016-03-30 四川大学 吲哚酮化合物或其衍生物及其用途
JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク. エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
US11397178B2 (en) 2016-10-28 2022-07-26 Cedars-Sinai Medical Center Method of predicting progression of idiopathic pulmonary fibrosis and monitoring of therapeutic efficacy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6762180B1 (en) * 1999-10-13 2004-07-13 Boehringer Ingelheim Pharma Kg Substituted indolines which inhibit receptor tyrosine kinases
UA75054C2 (uk) 1999-10-13 2006-03-15 Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу
DE10233500A1 (de) * 2002-07-24 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel
DE10237423A1 (de) 2002-08-16 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen
US20040204458A1 (en) * 2002-08-16 2004-10-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of Lck inhibitors for treatment of immunologic diseases
US20050043233A1 (en) * 2003-04-29 2005-02-24 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
EP1571225A1 (en) 2004-03-02 2005-09-07 PrimaGen Holding B.V. Diagnosis of a disease and monitoring of therapy using the AC133 gene
PE20060777A1 (es) 2004-12-24 2006-10-06 Boehringer Ingelheim Int Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
EP1777523A1 (en) 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
US8557531B2 (en) 2006-04-18 2013-10-15 Wellstat Biologics Corporation Detection of circulating endothelial cells
EP1870400A1 (en) 2006-06-08 2007-12-26 Boehringer Ingelheim Pharma GmbH & Co. KG Salts and crystalline salt forms of an 2-indolinone derivative
CA2662591A1 (en) * 2006-09-07 2008-03-13 Astrazenca Ab Method for evaluating patients for treatment with drugs targeting ret receptor tyrosine kinase
KR20090128474A (ko) 2007-04-13 2009-12-15 브리스톨-마이어스 스큅 컴퍼니 혈관 내피 성장인자 수용체-2 조절제에 대한 감수성을 판정하기 위한 방법 및 바이오마커
WO2008134526A2 (en) 2007-04-27 2008-11-06 University Of Florida Research Foundation Inc. Glycoprotein profiling of bladder cancer

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