JP2012520446A5 - - Google Patents
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- Publication number
- JP2012520446A5 JP2012520446A5 JP2011553450A JP2011553450A JP2012520446A5 JP 2012520446 A5 JP2012520446 A5 JP 2012520446A5 JP 2011553450 A JP2011553450 A JP 2011553450A JP 2011553450 A JP2011553450 A JP 2011553450A JP 2012520446 A5 JP2012520446 A5 JP 2012520446A5
- Authority
- JP
- Japan
- Prior art keywords
- monitoring
- biomarker
- cells
- methyl
- dim
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09154964 | 2009-03-12 | ||
| EP09154964.2 | 2009-03-12 | ||
| PCT/EP2010/053063 WO2010103058A1 (en) | 2009-03-12 | 2010-03-11 | Method or system using biomarkers for the monitoring of a treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012520446A JP2012520446A (ja) | 2012-09-06 |
| JP2012520446A5 true JP2012520446A5 (https=) | 2013-04-25 |
| JP5667581B2 JP5667581B2 (ja) | 2015-02-12 |
Family
ID=42129920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553450A Expired - Fee Related JP5667581B2 (ja) | 2009-03-12 | 2010-03-11 | 治療をモニターするためのバイオマーカーを使用した方法またはシステム |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8802384B2 (https=) |
| EP (1) | EP2406628A1 (https=) |
| JP (1) | JP5667581B2 (https=) |
| KR (1) | KR20110137307A (https=) |
| CN (1) | CN102334030A (https=) |
| AR (1) | AR076113A1 (https=) |
| AU (1) | AU2010223256B2 (https=) |
| BR (1) | BRPI1011688A2 (https=) |
| CA (1) | CA2755055A1 (https=) |
| CL (1) | CL2011002260A1 (https=) |
| CO (1) | CO6430497A2 (https=) |
| EA (1) | EA201101300A1 (https=) |
| EC (1) | ECSP11011323A (https=) |
| IL (1) | IL214747A0 (https=) |
| MA (1) | MA33120B1 (https=) |
| MX (1) | MX2011009482A (https=) |
| NZ (1) | NZ594843A (https=) |
| PE (1) | PE20120592A1 (https=) |
| SG (1) | SG174324A1 (https=) |
| TN (1) | TN2011000457A1 (https=) |
| TW (1) | TW201100802A (https=) |
| UA (1) | UA107789C2 (https=) |
| UY (1) | UY32482A (https=) |
| WO (1) | WO2010103058A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA104590C2 (ru) * | 2008-06-06 | 2014-02-25 | Берингер Ингельхайм Интернациональ Гмбх | Капсулированная лекарственная форма, содержащая суспензионную композицию производной индолинона |
| UA107560C2 (uk) * | 2008-06-06 | 2015-01-26 | Фармацевтична лікарська форма для негайного вивільнення похідної індолінону | |
| US20170065529A1 (en) | 2015-09-09 | 2017-03-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical dosage form for immediate release of an indolinone derivative |
| US20140350022A1 (en) | 2013-05-10 | 2014-11-27 | Boehringer Ingelheim International Gmbh | Efficacious treatment of NSCLC and predictive clinical marker of the responsiveness of a tumour to a treatment |
| CN104003925B (zh) * | 2013-06-05 | 2016-03-30 | 四川大学 | 吲哚酮化合物或其衍生物及其用途 |
| EP3782604A1 (en) | 2013-07-31 | 2021-02-24 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
| US11397178B2 (en) | 2016-10-28 | 2022-07-26 | Cedars-Sinai Medical Center | Method of predicting progression of idiopathic pulmonary fibrosis and monitoring of therapeutic efficacy |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA75054C2 (uk) | 1999-10-13 | 2006-03-15 | Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг | Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу |
| US6762180B1 (en) * | 1999-10-13 | 2004-07-13 | Boehringer Ingelheim Pharma Kg | Substituted indolines which inhibit receptor tyrosine kinases |
| DE10233500A1 (de) * | 2002-07-24 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel |
| US20040204458A1 (en) * | 2002-08-16 | 2004-10-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of Lck inhibitors for treatment of immunologic diseases |
| DE10237423A1 (de) | 2002-08-16 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| EP1571225A1 (en) | 2004-03-02 | 2005-09-07 | PrimaGen Holding B.V. | Diagnosis of a disease and monitoring of therapy using the AC133 gene |
| PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| JP2009534666A (ja) | 2006-04-18 | 2009-09-24 | ウェルスタット バイオロジックス コーポレイション | 循環内皮細胞の検出 |
| EP1870400A1 (en) * | 2006-06-08 | 2007-12-26 | Boehringer Ingelheim Pharma GmbH & Co. KG | Salts and crystalline salt forms of an 2-indolinone derivative |
| AU2007293280A1 (en) * | 2006-09-07 | 2008-03-13 | Astrazeneca Ab | Method for evaluating patients for treatment with drugs targeting RET receptor tyrosine kinase |
| US20100234381A1 (en) | 2007-04-13 | 2010-09-16 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| WO2008134526A2 (en) | 2007-04-27 | 2008-11-06 | University Of Florida Research Foundation Inc. | Glycoprotein profiling of bladder cancer |
-
2010
- 2010-03-09 US US12/720,663 patent/US8802384B2/en not_active Expired - Fee Related
- 2010-03-10 UY UY0001032482A patent/UY32482A/es not_active Application Discontinuation
- 2010-03-11 BR BRPI1011688A patent/BRPI1011688A2/pt not_active IP Right Cessation
- 2010-03-11 EP EP10709198A patent/EP2406628A1/en not_active Withdrawn
- 2010-03-11 CN CN201080009568XA patent/CN102334030A/zh active Pending
- 2010-03-11 MA MA34165A patent/MA33120B1/fr unknown
- 2010-03-11 PE PE2011001619A patent/PE20120592A1/es not_active Application Discontinuation
- 2010-03-11 EA EA201101300A patent/EA201101300A1/ru unknown
- 2010-03-11 AR ARP100100765A patent/AR076113A1/es unknown
- 2010-03-11 SG SG2011065224A patent/SG174324A1/en unknown
- 2010-03-11 CA CA2755055A patent/CA2755055A1/en not_active Abandoned
- 2010-03-11 JP JP2011553450A patent/JP5667581B2/ja not_active Expired - Fee Related
- 2010-03-11 TW TW099107108A patent/TW201100802A/zh unknown
- 2010-03-11 MX MX2011009482A patent/MX2011009482A/es active IP Right Grant
- 2010-03-11 AU AU2010223256A patent/AU2010223256B2/en not_active Ceased
- 2010-03-11 KR KR1020117021089A patent/KR20110137307A/ko not_active Withdrawn
- 2010-03-11 WO PCT/EP2010/053063 patent/WO2010103058A1/en not_active Ceased
- 2010-03-11 NZ NZ594843A patent/NZ594843A/en not_active IP Right Cessation
- 2010-11-03 UA UAA201111801A patent/UA107789C2/ru unknown
-
2011
- 2011-08-18 IL IL214747A patent/IL214747A0/en unknown
- 2011-09-09 TN TN2011000457A patent/TN2011000457A1/fr unknown
- 2011-09-12 CL CL2011002260A patent/CL2011002260A1/es unknown
- 2011-09-12 CO CO11117849A patent/CO6430497A2/es not_active Application Discontinuation
- 2011-09-13 EC EC2011011323A patent/ECSP11011323A/es unknown
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