AU2010223256B2 - Method or system using biomarkers for the monitoring of a treatment - Google Patents
Method or system using biomarkers for the monitoring of a treatment Download PDFInfo
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- AU2010223256B2 AU2010223256B2 AU2010223256A AU2010223256A AU2010223256B2 AU 2010223256 B2 AU2010223256 B2 AU 2010223256B2 AU 2010223256 A AU2010223256 A AU 2010223256A AU 2010223256 A AU2010223256 A AU 2010223256A AU 2010223256 B2 AU2010223256 B2 AU 2010223256B2
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5064—Endothelial cells
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- A—HUMAN NECESSITIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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Landscapes
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09154964 | 2009-03-12 | ||
| EP09154964.2 | 2009-03-12 | ||
| PCT/EP2010/053063 WO2010103058A1 (en) | 2009-03-12 | 2010-03-11 | Method or system using biomarkers for the monitoring of a treatment |
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| AU2010223256A1 AU2010223256A1 (en) | 2011-09-15 |
| AU2010223256B2 true AU2010223256B2 (en) | 2014-08-21 |
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| JP (1) | JP5667581B2 (https=) |
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| PE (1) | PE20120592A1 (https=) |
| SG (1) | SG174324A1 (https=) |
| TN (1) | TN2011000457A1 (https=) |
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| UA (1) | UA107789C2 (https=) |
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| MX2010013203A (es) * | 2008-06-06 | 2011-02-25 | Boehringer Ingelheim Int | Forma de dosificacion farmaceutica en capsula que comprende una formulacion en suspension de un derivado de indolinona. |
| US20170065529A1 (en) | 2015-09-09 | 2017-03-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical dosage form for immediate release of an indolinone derivative |
| US20140350022A1 (en) | 2013-05-10 | 2014-11-27 | Boehringer Ingelheim International Gmbh | Efficacious treatment of NSCLC and predictive clinical marker of the responsiveness of a tumour to a treatment |
| CN104003925B (zh) * | 2013-06-05 | 2016-03-30 | 四川大学 | 吲哚酮化合物或其衍生物及其用途 |
| JP6799201B2 (ja) | 2013-07-31 | 2020-12-16 | アヴァリン ファーマ インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
| US11397178B2 (en) | 2016-10-28 | 2022-07-26 | Cedars-Sinai Medical Center | Method of predicting progression of idiopathic pulmonary fibrosis and monitoring of therapeutic efficacy |
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| UA75054C2 (uk) | 1999-10-13 | 2006-03-15 | Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг | Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу |
| DE10237423A1 (de) | 2002-08-16 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen |
| US20040204458A1 (en) * | 2002-08-16 | 2004-10-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of Lck inhibitors for treatment of immunologic diseases |
| US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| EP1571225A1 (en) | 2004-03-02 | 2005-09-07 | PrimaGen Holding B.V. | Diagnosis of a disease and monitoring of therapy using the AC133 gene |
| PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| US8557531B2 (en) | 2006-04-18 | 2013-10-15 | Wellstat Biologics Corporation | Detection of circulating endothelial cells |
| EP1870400A1 (en) | 2006-06-08 | 2007-12-26 | Boehringer Ingelheim Pharma GmbH & Co. KG | Salts and crystalline salt forms of an 2-indolinone derivative |
| CA2662591A1 (en) * | 2006-09-07 | 2008-03-13 | Astrazenca Ab | Method for evaluating patients for treatment with drugs targeting ret receptor tyrosine kinase |
| KR20090128474A (ko) | 2007-04-13 | 2009-12-15 | 브리스톨-마이어스 스큅 컴퍼니 | 혈관 내피 성장인자 수용체-2 조절제에 대한 감수성을 판정하기 위한 방법 및 바이오마커 |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004013099A1 (en) * | 2002-07-24 | 2004-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate and the use thereof as a pharmaceutical composition |
Non-Patent Citations (2)
| Title |
|---|
| Bertolini, F. et al (2006) Nature Reviews 6: 835-845 * |
| Vroling, L. et al (2009) Angiogenesis 12: 69-79 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100233705A1 (en) | 2010-09-16 |
| JP5667581B2 (ja) | 2015-02-12 |
| EP2406628A1 (en) | 2012-01-18 |
| AU2010223256A1 (en) | 2011-09-15 |
| CA2755055A1 (en) | 2010-09-16 |
| CO6430497A2 (es) | 2012-04-30 |
| IL214747A0 (en) | 2011-11-30 |
| ECSP11011323A (es) | 2011-10-31 |
| EA201101300A1 (ru) | 2012-04-30 |
| AR076113A1 (es) | 2011-05-18 |
| PE20120592A1 (es) | 2012-06-09 |
| UY32482A (es) | 2010-10-29 |
| SG174324A1 (en) | 2011-10-28 |
| NZ594843A (en) | 2014-03-28 |
| CN102334030A (zh) | 2012-01-25 |
| TN2011000457A1 (en) | 2013-03-27 |
| MA33120B1 (fr) | 2012-03-01 |
| UA107789C2 (en) | 2015-02-25 |
| US8802384B2 (en) | 2014-08-12 |
| WO2010103058A1 (en) | 2010-09-16 |
| TW201100802A (en) | 2011-01-01 |
| KR20110137307A (ko) | 2011-12-22 |
| CL2011002260A1 (es) | 2012-03-23 |
| MX2011009482A (es) | 2011-09-27 |
| JP2012520446A (ja) | 2012-09-06 |
| BRPI1011688A2 (pt) | 2016-03-22 |
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