JP2012517430A5 - - Google Patents
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- Publication number
- JP2012517430A5 JP2012517430A5 JP2011549205A JP2011549205A JP2012517430A5 JP 2012517430 A5 JP2012517430 A5 JP 2012517430A5 JP 2011549205 A JP2011549205 A JP 2011549205A JP 2011549205 A JP2011549205 A JP 2011549205A JP 2012517430 A5 JP2012517430 A5 JP 2012517430A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer matrix
- bioactive agent
- ultrasound
- bound
- linked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 35
- 239000011159 matrix material Substances 0.000 claims description 34
- 229920000642 polymer Polymers 0.000 claims description 29
- 239000012867 bioactive agent Substances 0.000 claims description 24
- 238000002604 ultrasonography Methods 0.000 claims description 11
- 229920006299 self-healing polymer Polymers 0.000 claims description 5
- 238000009792 diffusion process Methods 0.000 claims description 4
- 230000001939 inductive effect Effects 0.000 claims description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 2
- 229940072056 alginate Drugs 0.000 claims description 2
- 235000010443 alginic acid Nutrition 0.000 claims description 2
- 229920000615 alginic acid Polymers 0.000 claims description 2
- 230000003993 interaction Effects 0.000 claims description 2
- 230000004962 physiological condition Effects 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- -1 cation cation Chemical class 0.000 claims 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15127709P | 2009-02-10 | 2009-02-10 | |
| US61/151,277 | 2009-02-10 | ||
| PCT/US2010/022769 WO2010093528A2 (en) | 2009-02-10 | 2010-02-01 | On-demand and reversible drug release by external cue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012517430A JP2012517430A (ja) | 2012-08-02 |
| JP2012517430A5 true JP2012517430A5 (enExample) | 2013-03-21 |
Family
ID=42562244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549205A Pending JP2012517430A (ja) | 2009-02-10 | 2010-02-01 | 外部からの合図によるオンデマンドで可逆的な薬物放出 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20120035531A1 (enExample) |
| EP (1) | EP2395981A4 (enExample) |
| JP (1) | JP2012517430A (enExample) |
| CN (1) | CN102316855A (enExample) |
| WO (1) | WO2010093528A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8753309B2 (en) | 2011-06-24 | 2014-06-17 | The Invention Science Fund I, Llc | Device, system, and method including micro-patterned cell treatment array |
| WO2013103956A1 (en) * | 2012-01-05 | 2013-07-11 | President And Fellows Of Harvard College | Interpenetrating networks with covalent and ionic crosslinks |
| US12029829B2 (en) | 2016-03-22 | 2024-07-09 | President And Fellows Of Harvard College | Biocompatible adhesives and methods of use thereof |
| EP4031131A4 (en) | 2019-09-20 | 2024-01-03 | President and Fellows of Harvard College | STRONG GEL DRUG DELIVERY COMPOSITIONS AND ASSOCIATED METHODS |
| WO2021174021A1 (en) * | 2020-02-27 | 2021-09-02 | Fred Hutchinson Cancer Research Center | Tunable extended release hydrogels |
| CN114681437A (zh) * | 2020-12-30 | 2022-07-01 | 苏州百迈生物医药有限公司 | 一种米托蒽醌组合物及其制备方法 |
| US20240285764A1 (en) * | 2021-06-21 | 2024-08-29 | Sorbonne Université | Sonosensitive composition |
| CA3231244A1 (en) * | 2021-09-07 | 2023-03-16 | Julien H. ARRIZABALAGA | Methods and systems for ultrasound stimulated structures and delivery of therapeutic species |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657543A (en) * | 1984-07-23 | 1987-04-14 | Massachusetts Institute Of Technology | Ultrasonically modulated polymeric devices for delivering compositions |
| EP1374908A3 (en) * | 1998-10-09 | 2004-03-24 | The Regents Of The University Of Michigan | Polymer-drug conjugates comprising hydrazide linkers |
| US6748954B2 (en) * | 2000-10-27 | 2004-06-15 | The Regents Of The University Of Michigan | Drug release from polymer matrices through mechanical stimulation |
| NL1023720C2 (nl) * | 2003-06-23 | 2004-12-28 | Univ Eindhoven Tech | Werkwijze voor het wijzigen van de transporteigenschappen van een materiaal, werkwijze voor het vrijmaken van een werkstof uit een implantaat, evenals implantaat met werkstof. |
| WO2007024972A2 (en) * | 2005-08-22 | 2007-03-01 | Quick-Med Technologies, Inc. | Non-leaching absorbent wound dressing |
-
2010
- 2010-02-01 WO PCT/US2010/022769 patent/WO2010093528A2/en not_active Ceased
- 2010-02-01 EP EP10741563.0A patent/EP2395981A4/en not_active Withdrawn
- 2010-02-01 US US13/147,870 patent/US20120035531A1/en not_active Abandoned
- 2010-02-01 CN CN2010800072705A patent/CN102316855A/zh active Pending
- 2010-02-01 JP JP2011549205A patent/JP2012517430A/ja active Pending
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