JP2012515170A - 膣上皮境界潤滑の治療的調節 - Google Patents

膣上皮境界潤滑の治療的調節 Download PDF

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JP2012515170A
JP2012515170A JP2011545542A JP2011545542A JP2012515170A JP 2012515170 A JP2012515170 A JP 2012515170A JP 2011545542 A JP2011545542 A JP 2011545542A JP 2011545542 A JP2011545542 A JP 2011545542A JP 2012515170 A JP2012515170 A JP 2012515170A
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pharmaceutical composition
prg4
composition according
vaginal
therapeutic agent
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トゥルイット,エドワード,アール.,サード
サリバン,ベンジャミン
サリバン,デイビッド
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シンギュラリス,インク.
シェペンズ アイ リサーチ インスティテュート
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/19Cytokines; Lymphokines; Interferons
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    • A61K38/22Hormones
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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2011545542A 2009-01-13 2010-01-13 膣上皮境界潤滑の治療的調節 Pending JP2012515170A (ja)

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US14434409P 2009-01-13 2009-01-13
US61/144,344 2009-01-13
US26040209P 2009-11-12 2009-11-12
US61/260,402 2009-11-12
PCT/US2010/020929 WO2010083239A2 (en) 2009-01-13 2010-01-13 Therapeutic modulation of vaginal epithelium boundary lubrication

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JP2012515170A5 JP2012515170A5 (https=) 2012-09-13

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US (1) US8980840B2 (https=)
EP (1) EP2381957B1 (https=)
JP (2) JP2012515170A (https=)
CN (1) CN102438645A (https=)
CA (1) CA2749480C (https=)
ES (1) ES2534082T3 (https=)
WO (1) WO2010083239A2 (https=)

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JP2015180620A (ja) * 2009-01-13 2015-10-15 ルブリス,エルエルシー. 膣上皮境界潤滑の治療的調節
JP2018505867A (ja) * 2015-01-26 2018-03-01 ルブリス,エルエルシー. 抗炎症剤としてのprg4の使用

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US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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WO2015060935A1 (en) 2013-10-22 2015-04-30 Lubris, Llc Control of rheological properties of mixed hyaluronate/lubricin solutions
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RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
CA2965372C (en) 2014-10-22 2023-09-05 Havah Therapeutics Pty Ltd Methods of reducing mammographic breast density and/or breast cancer risk
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP2018534291A (ja) 2015-10-22 2018-11-22 ハバフ セラピューティクス ピーティーワイ エルティーディー マンモグラフィ乳房密度及び/又は乳癌のリスクを低下させる方法
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
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AU2020287392A1 (en) 2019-06-03 2021-12-23 Havah Therapeutics Pty Ltd Pharmaceutical formulations and systems for delivery of an androgenic agent and an aromatase inhibitor and methods for use
WO2023042216A1 (en) * 2021-09-15 2023-03-23 Chemex Global Topical pharmaceutical compositions for treatment of infertility
CN118976097B (zh) * 2024-10-22 2025-01-24 北京岷德生物科技有限公司 一种治疗妇科疾病的组合物及其制备方法和应用

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US7027A (en) * 1850-01-15 Circulak
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JP2015180620A (ja) * 2009-01-13 2015-10-15 ルブリス,エルエルシー. 膣上皮境界潤滑の治療的調節
JP2018505867A (ja) * 2015-01-26 2018-03-01 ルブリス,エルエルシー. 抗炎症剤としてのprg4の使用
JP2020189878A (ja) * 2015-01-26 2020-11-26 ルブリス,エルエルシー. 抗炎症剤としてのprg4の使用
JP7212653B2 (ja) 2015-01-26 2023-01-25 ルブリス,エルエルシー. 抗炎症剤としてのprg4の使用

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US20120052077A1 (en) 2012-03-01
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ES2534082T3 (es) 2015-04-17
EP2381957B1 (en) 2015-01-07
EP2381957A4 (en) 2013-12-25
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