JP2012513472A5 - - Google Patents
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- Publication number
- JP2012513472A5 JP2012513472A5 JP2011543616A JP2011543616A JP2012513472A5 JP 2012513472 A5 JP2012513472 A5 JP 2012513472A5 JP 2011543616 A JP2011543616 A JP 2011543616A JP 2011543616 A JP2011543616 A JP 2011543616A JP 2012513472 A5 JP2012513472 A5 JP 2012513472A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- group
- mmp
- disease
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*(cc1)ccc1C#Cc([s]1)ccc1S(*[C@](CCc1c[n]c2c1c(F)c(*)c(F)c2F)C(O)=O)(=*)=O Chemical compound C*(cc1)ccc1C#Cc([s]1)ccc1S(*[C@](CCc1c[n]c2c1c(F)c(*)c(F)c2F)C(O)=O)(=*)=O 0.000 description 19
- TZCPFFOTNVEILK-UHFFFAOYSA-N CC(c1c(c(O)c2O)O)=C(O)S(C)c1c2O Chemical compound CC(c1c(c(O)c2O)O)=C(O)S(C)c1c2O TZCPFFOTNVEILK-UHFFFAOYSA-N 0.000 description 1
- HHRDFEPCDXCTJB-UHFFFAOYSA-N OC(CNC1C2C1C2)=O Chemical compound OC(CNC1C2C1C2)=O HHRDFEPCDXCTJB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20354808P | 2008-12-23 | 2008-12-23 | |
| US61/203,548 | 2008-12-23 | ||
| US21486309P | 2009-04-29 | 2009-04-29 | |
| US61/214,863 | 2009-04-29 | ||
| PCT/US2009/069005 WO2010075287A2 (en) | 2008-12-23 | 2009-12-21 | Compounds and methods for the treatment of pain and other diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015015025A Division JP5913651B2 (ja) | 2008-12-23 | 2015-01-29 | 疼痛および他の疾患の処置のための化合物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012513472A JP2012513472A (ja) | 2012-06-14 |
| JP2012513472A5 true JP2012513472A5 (https=) | 2013-02-14 |
| JP5710498B2 JP5710498B2 (ja) | 2015-04-30 |
Family
ID=42288397
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543616A Expired - Fee Related JP5710498B2 (ja) | 2008-12-23 | 2009-12-21 | 疼痛および他の疾患の処置のための化合物および方法 |
| JP2015015025A Active JP5913651B2 (ja) | 2008-12-23 | 2015-01-29 | 疼痛および他の疾患の処置のための化合物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015015025A Active JP5913651B2 (ja) | 2008-12-23 | 2015-01-29 | 疼痛および他の疾患の処置のための化合物および方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8765953B2 (https=) |
| EP (1) | EP2382206B1 (https=) |
| JP (2) | JP5710498B2 (https=) |
| KR (1) | KR101682427B1 (https=) |
| CN (1) | CN102325768B (https=) |
| AU (2) | AU2009330131B2 (https=) |
| BR (1) | BRPI0923688A2 (https=) |
| CA (1) | CA2747957C (https=) |
| ES (1) | ES2575689T3 (https=) |
| IL (1) | IL213703A (https=) |
| MX (1) | MX339096B (https=) |
| RU (1) | RU2528333C2 (https=) |
| WO (1) | WO2010075287A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8530453B2 (en) | 2009-09-28 | 2013-09-10 | Aquilus Pharmaceuticals, Inc. | Compounds and methods for the treatment of pain and other diseases |
| EP2681209B1 (en) * | 2011-03-02 | 2018-05-09 | Aquilus Pharmaceuticals, Inc | Compounds and methods for the treatment of pain and other disorders |
| JP2015166385A (ja) * | 2015-05-29 | 2015-09-24 | アクイラス ファーマシューティカルズ， インコーポレイテッド | 疼痛および他の障害の処置のための化合物および方法 |
| ES2974634T3 (es) | 2018-12-21 | 2024-06-28 | Celgene Corp | Inhibidores de tienopiridinas de RIPK2 |
| WO2020154243A1 (en) * | 2019-01-24 | 2020-07-30 | Aquilus Pharmaceuticals, Inc. | Compounds and methods for the treatment of degenerative disorders |
| EP3952882A4 (en) * | 2019-04-09 | 2023-01-18 | Intrinsic Medicine, Inc. | IMMUNO-MODULATORY OLIGOSACCHARIDES FOR PAIN TREATMENT |
| EP3980007A1 (en) * | 2019-06-07 | 2022-04-13 | Selectimmune Pharma AB | Treatment and diagnosis of chronic inflammatory conditions in the lower urinary tract |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| CA2242416C (en) * | 1996-01-23 | 2006-03-21 | Shionogi & Co., Ltd. | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same |
| JP2002514179A (ja) * | 1996-09-04 | 2002-05-14 | ワーナー―ランバート・コンパニー | マトリックスメタロプロテイナーゼの阻害剤としてのビフェニル酪酸およびその誘導体 |
| DE19719621A1 (de) * | 1997-05-09 | 1998-11-12 | Hoechst Ag | Sulfonylaminocarbonsäuren |
| CA2297011C (en) * | 1997-07-22 | 2007-01-30 | Shionogi & Co., Ltd. | Sulfonamide derivatives as therapeutic or prophylactic agent for glomerulopathy |
| WO2000015213A1 (en) * | 1998-09-11 | 2000-03-23 | Shionogi & Co., Ltd. | Remedal or preventive agent for congestive heart failure |
| US6440710B1 (en) * | 1998-12-10 | 2002-08-27 | The Scripps Research Institute | Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds |
| PT1104760E (pt) * | 1999-12-03 | 2003-06-30 | Pfizer Prod Inc | Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios |
| US6727266B2 (en) * | 2000-01-26 | 2004-04-27 | Shionogi & Co., Ltd. | Substituted tryptophan derivatives |
| CA2406401A1 (en) * | 2000-04-19 | 2002-10-16 | Shionogi & Co., Ltd. | Process for preparation of sulfonamide derivatives and crystals thereof |
| AR028606A1 (es) * | 2000-05-24 | 2003-05-14 | Smithkline Beecham Corp | Nuevos inhibidores de mmp-2/mmp-9 |
| TW200413273A (en) * | 2002-11-15 | 2004-08-01 | Wako Pure Chem Ind Ltd | Heavy hydrogenation method of heterocyclic rings |
| JP2007516982A (ja) | 2003-12-15 | 2007-06-28 | 日本たばこ産業株式会社 | シクロプロパン化合物及びその医薬用途 |
| CN101309917B (zh) * | 2005-10-06 | 2013-09-11 | 奥斯拜客斯制药有限公司 | 具有增强治疗性质的胃h+，k+-atp酶氘代抑制剂 |
| US7750168B2 (en) * | 2006-02-10 | 2010-07-06 | Sigma-Aldrich Co. | Stabilized deuteroborane-tetrahydrofuran complex |
| WO2008071453A1 (en) * | 2006-12-13 | 2008-06-19 | Bayer Schering Pharma Aktiengesellschaft | 1,2-diarylacetylene derivatives of acyltryptophanols |
-
2009
- 2009-12-21 KR KR1020117016625A patent/KR101682427B1/ko active Active
- 2009-12-21 AU AU2009330131A patent/AU2009330131B2/en active Active
- 2009-12-21 WO PCT/US2009/069005 patent/WO2010075287A2/en not_active Ceased
- 2009-12-21 CN CN200980157184.XA patent/CN102325768B/zh active Active
- 2009-12-21 RU RU2011130381/04A patent/RU2528333C2/ru active
- 2009-12-21 MX MX2011006791A patent/MX339096B/es active IP Right Grant
- 2009-12-21 JP JP2011543616A patent/JP5710498B2/ja not_active Expired - Fee Related
- 2009-12-21 BR BRPI0923688A patent/BRPI0923688A2/pt not_active Application Discontinuation
- 2009-12-21 US US13/141,384 patent/US8765953B2/en active Active
- 2009-12-21 CA CA2747957A patent/CA2747957C/en active Active
- 2009-12-21 EP EP09835701.5A patent/EP2382206B1/en active Active
- 2009-12-21 ES ES09835701.5T patent/ES2575689T3/es active Active
-
2011
- 2011-06-21 IL IL213703A patent/IL213703A/en active IP Right Grant
-
2015
- 2015-01-29 JP JP2015015025A patent/JP5913651B2/ja active Active
- 2015-07-29 AU AU2015207867A patent/AU2015207867A1/en not_active Abandoned
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