JP2012511917A5 - - Google Patents
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- Publication number
- JP2012511917A5 JP2012511917A5 JP2011541165A JP2011541165A JP2012511917A5 JP 2012511917 A5 JP2012511917 A5 JP 2012511917A5 JP 2011541165 A JP2011541165 A JP 2011541165A JP 2011541165 A JP2011541165 A JP 2011541165A JP 2012511917 A5 JP2012511917 A5 JP 2012511917A5
- Authority
- JP
- Japan
- Prior art keywords
- lymphocytes
- amplification product
- mammal
- seq
- methylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20080021838 EP2199411B1 (en) | 2008-12-16 | 2008-12-16 | Epigenetic markers for the identification of CD3 positive T-lymphocytes |
| EP08021838.1 | 2008-12-16 | ||
| PCT/EP2009/008764 WO2010069499A2 (en) | 2008-12-16 | 2009-12-08 | Epigenetic markers for the identification of blood sub-cells of type 1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012511917A JP2012511917A (ja) | 2012-05-31 |
| JP2012511917A5 true JP2012511917A5 (https=) | 2012-12-20 |
Family
ID=40428037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541165A Pending JP2012511917A (ja) | 2008-12-16 | 2009-12-08 | １型の血液細胞成分の同定のためのエピジェネティックマーカー |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120107810A1 (https=) |
| EP (2) | EP2199411B1 (https=) |
| JP (1) | JP2012511917A (https=) |
| CA (1) | CA2747312C (https=) |
| DK (2) | DK2199411T3 (https=) |
| ES (1) | ES2606350T3 (https=) |
| PL (1) | PL2376648T3 (https=) |
| WO (1) | WO2010069499A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170233807A1 (en) | 2008-12-16 | 2017-08-17 | Epiontis Gmbh | Epigenetic Markers for the Identification of Blood Sub-cells of Type 1 |
| US20130281304A1 (en) * | 2010-08-13 | 2013-10-24 | Andrew P. Feinberg | Comprehensive Methylome Map of Myeloid and Lymphoid Commitment from Hematopoietic Proenitors |
| WO2012045888A1 (en) | 2010-10-08 | 2012-04-12 | Epiontis Gmbh | Method for determining cancer patient survival based on analyzing tumor-infiltrating overall t-lymphocytes |
| JP2014505475A (ja) * | 2011-01-20 | 2014-03-06 | ユニヴェルシテ リブル ドゥ ブリュッセル | ヒトの乳癌のエピジェネティックな肖像 |
| US20140178348A1 (en) | 2011-05-25 | 2014-06-26 | The Regents Of The University Of California | Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies |
| CA2869295A1 (en) * | 2011-05-25 | 2012-11-29 | Brown University | Methods using dna methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies |
| WO2013135454A1 (en) * | 2012-03-12 | 2013-09-19 | Epiontis Gmbh | Epigenetic marker for the identification of cd3cd4 positive t lymphocytes |
| GB201221133D0 (en) * | 2012-11-23 | 2013-01-09 | Epiontis Gmbh | Epigenetic method for the identification of subpopulations of CD8 and T lympocytes, in particular CD8 alpha and beta T lymphocytes |
| JP6590790B2 (ja) | 2013-04-19 | 2019-10-16 | エピオンティス ゲーエムベーハー | 生体サンプルにおける定量的細胞組成を特定する方法 |
| EP3360971A1 (en) * | 2017-02-09 | 2018-08-15 | Epiontis GmbH | Improved method for epigenetic immune cell counting |
| EP3382033B1 (en) * | 2017-03-30 | 2020-08-05 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen | Method for determining blood counts based on dna methylation |
| DE102017125019B4 (de) * | 2017-10-25 | 2019-10-17 | Epiontis Gmbh | PDCD1 als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere PD1+ Zellen |
| DE102018116353B4 (de) * | 2018-07-05 | 2020-06-10 | Epiontis Gmbh | Verfahren zum Nachweis und zur Zählung epigenetischer Immunzellen in humanen Blutproben für Immundiagnostik und Neugeborenen-Screening |
| CN116949156B (zh) * | 2023-09-19 | 2023-12-08 | 美迪西普亚医药科技(上海)有限公司 | 一种基于核酸变体的通用型检测人t细胞的分析方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002171973A (ja) * | 2000-12-07 | 2002-06-18 | Univ Tokyo | Ｄｎａメチル化パターンによる細胞の同定法 |
| WO2004050706A2 (en) | 2002-12-03 | 2004-06-17 | Medical Research Council | Regulatory t-cells |
| ES2367012T3 (es) | 2006-02-28 | 2011-10-27 | Charite-Universitätsmedizin Berlin | Detección y control de calidad de linfocitos t reguladores a través del análisis de metilación del adn del gen foxp3. |
-
2008
- 2008-12-16 DK DK08021838.1T patent/DK2199411T3/en active
- 2008-12-16 EP EP20080021838 patent/EP2199411B1/en active Active
-
2009
- 2009-12-08 CA CA2747312A patent/CA2747312C/en active Active
- 2009-12-08 WO PCT/EP2009/008764 patent/WO2010069499A2/en not_active Ceased
- 2009-12-08 US US13/139,808 patent/US20120107810A1/en not_active Abandoned
- 2009-12-08 DK DK09771304.4T patent/DK2376648T3/da active
- 2009-12-08 EP EP09771304.4A patent/EP2376648B1/en active Active
- 2009-12-08 PL PL09771304T patent/PL2376648T3/pl unknown
- 2009-12-08 ES ES09771304.4T patent/ES2606350T3/es active Active
- 2009-12-08 JP JP2011541165A patent/JP2012511917A/ja active Pending
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